메뉴 건너뛰기




Volumn 3, Issue 3, 2015, Pages 230-238

Treatment of nonalcoholic fatty liver disease: The role of medical, surgical, and endoscopic weight loss

Author keywords

Bariatric surgery; Endoscopic therapy; Exercise; Fatty liver; Nonalcoholic steatohepatitis; Pharmacotherapy; Weight loss

Indexed keywords


EID: 84969997322     PISSN: 22250719     EISSN: 23108819     Source Type: Journal    
DOI: 10.14218/JCTH.2015.00019     Document Type: Review
Times cited : (39)

References (82)
  • 1
    • 34248394769 scopus 로고    scopus 로고
    • Nonalcoholic fatty liver disease
    • Angulo P. Nonalcoholic fatty liver disease. Rev Gastroenterol Mex 2005;70: 52–56.
    • (2005) Rev Gastroenterol Mex , vol.70 , pp. 52-56
    • Angulo, P.1
  • 2
    • 10644220306 scopus 로고    scopus 로고
    • Prevalence of hepatic steatosis in an urban population in the United States: impact of ethnicity
    • Browning JD, Szczepaniak LS, Dobbins R, Nuremberg P, Horton JD, Cohen JC, et al. Prevalence of hepatic steatosis in an urban population in the United States: impact of ethnicity. Hepatology 2004;40:1387–1395. doi: 10. 1002/hep.20466.
    • (2004) Hepatology , vol.40 , pp. 1387-1395
    • Browning, JD1    Szczepaniak, LS2    Dobbins, R3    Nuremberg, P4    Horton, JD5    Cohen, JC6
  • 3
    • 36348935004 scopus 로고    scopus 로고
    • Incidence and natural course of fatty liver in the general population: the Dionysos study
    • Bedogni G, Miglioli L, Masutti F, Castiglione A, Crocè LS, Tiribelli C, et al. Incidence and natural course of fatty liver in the general population: the Dionysos study. Hepatology 2007;46:1387–1391. doi: 10.1002/hep.21827.
    • (2007) Hepatology , vol.46 , pp. 1387-1391
    • Bedogni, G1    Miglioli, L2    Masutti, F3    Castiglione, A4    Crocè, LS5    Tiribelli, C6
  • 4
    • 79960029926 scopus 로고    scopus 로고
    • Systematic review: the epidemiology and natural history of non-alcoholic fatty liver disease and non-alcoholic steatohepatitis in adults
    • Vernon G, Baranova A, Younossi ZM. Systematic review: the epidemiology and natural history of non-alcoholic fatty liver disease and non-alcoholic steatohepatitis in adults. Aliment Pharmacol Ther 2011;34:274–285. doi: 10.1111/j.1365-2036.2011.04724.x.
    • (2011) Aliment Pharmacol Ther , vol.34 , pp. 274-285
    • Vernon, G1    Baranova, A2    Younossi, ZM.3
  • 6
    • 22344452893 scopus 로고    scopus 로고
    • The natural history of nonalcoholic fatty liver disease: a population-based cohort study
    • Adams LA, Lymp JF, St Sauver J, Sanderson SO, Lindor KD, Feldstein A, et al. The natural history of nonalcoholic fatty liver disease: a population-based cohort study. Gastroenterology 2005;129:113–121. doi: 10.1053/j.gastro. 2005.04.014.
    • (2005) Gastroenterology , vol.129 , pp. 113-121
    • Adams, LA1    Lymp, JF2    St Sauver, J3    Sanderson, SO4    Lindor, KD5    Feldstein, A6
  • 7
    • 0036302288 scopus 로고    scopus 로고
    • Expanding the natural history of nonalcoholic steatohepatitis: from crypto-genic cirrhosis to hepatocellular carcinoma
    • Bugianesi E, Leone N, Vanni E, Marchesini G, Brunello F, Carucci P, et al. Expanding the natural history of nonalcoholic steatohepatitis: from crypto-genic cirrhosis to hepatocellular carcinoma. Gastroenterology 2002;123: 134–140. doi: 10.1053/gast.2002.34168.
    • (2002) Gastroenterology , vol.123 , pp. 134-140
    • Bugianesi, E1    Leone, N2    Vanni, E3    Marchesini, G4    Brunello, F5    Carucci, P6
  • 8
    • 84861543083 scopus 로고    scopus 로고
    • The diagnosis and management of non-alcoholic fatty liver disease: practice Guideline by the American Association for the Study of Liver Diseases, American College of Gastroenterology, and the American Gastroenterological Association
    • Chalasani N, Younossi Z, Lavine JE, Diehl AM, Brunt EM, Cusi K, et al. The diagnosis and management of non-alcoholic fatty liver disease: practice Guideline by the American Association for the Study of Liver Diseases, American College of Gastroenterology, and the American Gastroenterological Association. Hepatology 2012;55:2005–2023. doi: 10.1002/hep.25762.
    • (2012) Hepatology , vol.55 , pp. 2005-2023
    • Chalasani, N1    Younossi, Z2    Lavine, JE3    Diehl, AM4    Brunt, EM5    Cusi, K6
  • 9
    • 70349770695 scopus 로고    scopus 로고
    • Epidemiology and natural history of non-alcoholic steatohepatitis
    • Argo CK, Caldwell SH. Epidemiology and natural history of non-alcoholic steatohepatitis. Clin Liver Dis 2009;13:511–531. doi: 10.1016/j.cld.2009. 07.005.
    • (2009) Clin Liver Dis , vol.13 , pp. 511-531
    • Argo, CK1    Caldwell, SH.2
  • 10
    • 0038805259 scopus 로고    scopus 로고
    • The prevalence and etiology of elevated aminotransferase levels in the United States
    • Clark JM, Brancati FL, Diehl AM. The prevalence and etiology of elevated aminotransferase levels in the United States. Am J Gastroenterol 2003;98: 960–967. doi: 10.1111/j.1572-0241.2003.07486.x.
    • (2003) Am J Gastroenterol , vol.98 , pp. 960-967
    • Clark, JM1    Brancati, FL2    Diehl, AM.3
  • 11
    • 0037221394 scopus 로고    scopus 로고
    • Determinants of the association of overweight with elevated serum alanine aminotransferase activity in the United States
    • Ruhl CE, Everhart JE. Determinants of the association of overweight with elevated serum alanine aminotransferase activity in the United States. Gas-troenterology 2003;124:71–79. doi: 10.1053/gast.2003.50004.
    • (2003) Gas-troenterology , vol.124 , pp. 71-79
    • Ruhl, CE1    Everhart, JE.2
  • 12
    • 0037566201 scopus 로고    scopus 로고
    • Clinical and histologic spectrum of nonalcoholic fatty liver disease associated with normal ALT values
    • Mofrad P, Contos MJ, Haque M, Sargeant C, Fisher RA, Luketic VA, et al. Clinical and histologic spectrum of nonalcoholic fatty liver disease associated with normal ALT values. Hepatology 2003;37:1286–1292. doi: 10.1053/jhep.2003.50229.
    • (2003) Hepatology , vol.37 , pp. 1286-1292
    • Mofrad, P1    Contos, MJ2    Haque, M3    Sargeant, C4    Fisher, RA5    Luketic, VA6
  • 13
    • 84899649362 scopus 로고    scopus 로고
    • Comparison of liver fat indices for the diagnosis of hepatic steatosis and insulin resistance
    • Kahl S, Straßburger K, Nowotny B, Livingstone R, Klüppelholz B, Keßel K, et al. Comparison of liver fat indices for the diagnosis of hepatic steatosis and insulin resistance. PLoS One 2014;9:e94059. doi: 10.1371/journal.pone. 0094059.
    • (2014) PLoS One , vol.9 , pp. e94059
    • Kahl, S1    Straßburger, K2    Nowotny, B3    Livingstone, R4    Klüppelholz, B5    Keßel, K6
  • 14
    • 33751246499 scopus 로고    scopus 로고
    • The Fatty Liver Index: a simple and accurate predictor of hepatic stea-tosis in the general population
    • Bedogni G, Bellentani S, Miglioli L, Masutti F, Passalacqua M, Castiglione A, et al. The Fatty Liver Index: a simple and accurate predictor of hepatic stea-tosis in the general population. BMC Gastroenterol 2006;6:33. doi: 10.1186/1471-230X-6-33.
    • (2006) BMC Gastroenterol , vol.6 , pp. 33
    • Bedogni, G1    Bellentani, S2    Miglioli, L3    Masutti, F4    Passalacqua, M5    Castiglione, A6
  • 15
    • 84884419004 scopus 로고    scopus 로고
    • From NAFLD in clinical practice to answers from guidelines
    • Nascimbeni F, Pais R, Bellentani S, Day CP, Ratziu V, Loria P, et al. From NAFLD in clinical practice to answers from guidelines. J Hepatol 2013;59: 859–871. doi: 10.1016/j.jhep.2013.05.044.
    • (2013) J Hepatol , vol.59 , pp. 859-871
    • Nascimbeni, F1    Pais, R2    Bellentani, S3    Day, CP4    Ratziu, V5    Loria, P6
  • 16
    • 20444443042 scopus 로고    scopus 로고
    • Sampling variability of liver biopsy in nonalcoholic fatty liver disease
    • Ratziu V, Charlotte F, Heurtier A, Gombert S, Giral P, Bruckert E, et al. Sampling variability of liver biopsy in nonalcoholic fatty liver disease. Gastro-enterology 2005;128:1898–1906. doi: 10.1053/j.gastro.2005.03.084.
    • (2005) Gastro-enterology , vol.128 , pp. 1898-1906
    • Ratziu, V1    Charlotte, F2    Heurtier, A3    Gombert, S4    Giral, P5    Bruckert, E6
  • 17
    • 84930788424 scopus 로고    scopus 로고
    • Nonalcoholic fatty liver disease: a systematic review
    • Rinella ME. Nonalcoholic fatty liver disease: a systematic review. JAMA 2015; 313:2263–2273. doi: 10.1001/jama.2015.5370.
    • (2015) JAMA , vol.313 , pp. 2263-2273
    • Rinella, ME.1
  • 18
    • 20044374023 scopus 로고    scopus 로고
    • Design and validation of a histological scoring system for nonalcoholic fatty liver disease
    • Kleiner DE, Brunt EM, Van Natta M, Behling C, Contos MJ, Cummings OW, et al. Design and validation of a histological scoring system for nonalcoholic fatty liver disease. Hepatology 2005;41:1313–1321. doi: 10.1002/hep. 20701.
    • (2005) Hepatology , vol.41 , pp. 1313-1321
    • Kleiner, DE1    Brunt, EM2    Van Natta, M3    Behling, C4    Contos, MJ5    Cummings, OW6
  • 19
    • 80555136061 scopus 로고    scopus 로고
    • Meta-analysis: natural history of non-alcoholic fatty liver disease (NAFLD) and diagnostic accuracy of non-invasive tests for liver disease severity
    • Musso G, Gambino R, Cassader M, Pagano G. Meta-analysis: natural history of non-alcoholic fatty liver disease (NAFLD) and diagnostic accuracy of non-invasive tests for liver disease severity. Ann Med 2011;43:617–649. doi: 10.3109/07853890.2010.518623.
    • (2011) Ann Med , vol.43 , pp. 617-649
    • Musso, G1    Gambino, R2    Cassader, M3    Pagano, G.4
  • 20
    • 84876293750 scopus 로고    scopus 로고
    • Non-invasive diagnosis of non-alcoholic fatty liver disease. A critical appraisal
    • Machado MV, Cortez-Pinto H. Non-invasive diagnosis of non-alcoholic fatty liver disease. A critical appraisal. J Hepatol 2013;58:1007–1019. doi: 10.1016/j.jhep.2012.11.021.
    • (2013) J Hepatol , vol.58 , pp. 1007-1019
    • Machado, MV1    Cortez-Pinto, H.2
  • 21
    • 6944227798 scopus 로고    scopus 로고
    • Metabolic significance of nonalcoholic fatty liver disease in nonobese, nondiabetic adults
    • Kim HJ, Lee KE, Kim DJ, Kim SK, Ahn CW, Lim SK, et al. Metabolic significance of nonalcoholic fatty liver disease in nonobese, nondiabetic adults. Arch Intern Med 2004;164:2169–2175. doi: 10.1001/archinte.164.19.2169.
    • (2004) Arch Intern Med , vol.164 , pp. 2169-2175
    • Kim, HJ1    Lee, KE2    Kim, DJ3    Kim, SK4    Ahn, CW5    Lim, SK6
  • 22
    • 20944450486 scopus 로고    scopus 로고
    • Insulin resistance in non-diabetic patients with non-alcoholic fatty liver disease: sites and mechanisms
    • Bugianesi E, Gastaldelli A, Vanni E, Gambino R, Cassader M, Baldi S, et al. Insulin resistance in non-diabetic patients with non-alcoholic fatty liver disease: sites and mechanisms. Diabetologia 2005;48:634–642. doi: 10. 1007/s00125-005-1682-x.
    • (2005) Diabetologia , vol.48 , pp. 634-642
    • Bugianesi, E1    Gastaldelli, A2    Vanni, E3    Gambino, R4    Cassader, M5    Baldi, S6
  • 23
    • 18244382304 scopus 로고    scopus 로고
    • Sources of fatty acids stored in liver and secreted via lipoproteins in patients with nonalcoholic fatty liver disease
    • Donnelly KL, Smith CI, Schwarzenberg SJ, Jessurun J, Boldt MD, Parks EJ. Sources of fatty acids stored in liver and secreted via lipoproteins in patients with nonalcoholic fatty liver disease. J Clin Invest 2005;115:1343–1351. doi: 10.1172/JCI200523621.
    • (2005) J Clin Invest , vol.115 , pp. 1343-1351
    • Donnelly, KL1    Smith, CI2    Schwarzenberg, SJ3    Jessurun, J4    Boldt, MD5    Parks, EJ.6
  • 24
    • 84859404868 scopus 로고    scopus 로고
    • Role of obesity and lipotoxicity in the development of nonalcoholic steatohepatitis: pathophysiology and clinical implications
    • e6
    • Cusi K. Role of obesity and lipotoxicity in the development of nonalcoholic steatohepatitis: pathophysiology and clinical implications. Gastroenterology 2012;142:711–725, e6. doi: 10.1053/j.gastro.2012.02.003.
    • (2012) Gastroenterology , vol.142 , pp. 711-725
    • Cusi, K.1
  • 25
    • 33746536677 scopus 로고    scopus 로고
    • Carbohydrate response element binding protein, ChREBP, a transcription factor coupling hepatic glucose utilization and lipid synthesis
    • Uyeda K, Repa JJ. Carbohydrate response element binding protein, ChREBP, a transcription factor coupling hepatic glucose utilization and lipid synthesis. Cell Metab 2006;4:107–110. doi: 10.1016/j.cmet.2006.06.008.
    • (2006) Cell Metab , vol.4 , pp. 107-110
    • Uyeda, K1    Repa, JJ.2
  • 26
    • 84860497397 scopus 로고    scopus 로고
    • Diacylglycerol activation of protein kinase Cepsilon and hepatic insulin resistance
    • Jornayvaz FR, Shulman GI. Diacylglycerol activation of protein kinase Cepsilon and hepatic insulin resistance. Cell Metab 2012;15:574–584. doi: 10.1016/j.cmet.2012.03.005.
    • (2012) Cell Metab , vol.15 , pp. 574-584
    • Jornayvaz, FR1    Shulman, GI.2
  • 27
    • 0031947715 scopus 로고    scopus 로고
    • Steatohepatitis: a tale of two “hits”?
    • Day CP, James OF. Steatohepatitis: a tale of two “hits”? Gastroenterology 1998;114:842–845.
    • (1998) Gastroenterology , vol.114 , pp. 842-845
    • Day, CP1    James, OF.2
  • 28
    • 78049522194 scopus 로고    scopus 로고
    • Evolution of inflammation in nonalcoholic fatty liver disease: the multiple parallel hits hypothesis
    • Tilg H, Moschen AR. Evolution of inflammation in nonalcoholic fatty liver disease: the multiple parallel hits hypothesis. Hepatology 2010;52: 1836–1846. doi: 10.1002/hep.24001.
    • (2010) Hepatology , vol.52 , pp. 1836-1846
    • Tilg, H1    Moschen, AR.2
  • 29
    • 67649306197 scopus 로고    scopus 로고
    • Systematic review of risk factors for fibrosis progression in non-alcoholic steatohepatitis
    • Argo CK, Northup PG, Al-Osaimi AM, Caldwell SH. Systematic review of risk factors for fibrosis progression in non-alcoholic steatohepatitis. J Hepatol 2009;51:371–379. doi: 10.1016/j.jhep.2009.03.019.
    • (2009) J Hepatol , vol.51 , pp. 371-379
    • Argo, CK1    Northup, PG2    Al-Osaimi, AM3    Caldwell, SH.4
  • 30
    • 0028875908 scopus 로고
    • The natural history of nonalcoholic fatty liver: a follow-up study
    • Teli MR, James OF, Burt AD, Bennett MK, Day CP. The natural history of nonalcoholic fatty liver: a follow-up study. Hepatology 1995;22:1714–1719.
    • (1995) Hepatology , vol.22 , pp. 1714-1719
    • Teli, MR1    James, OF2    Burt, AD3    Bennett, MK4    Day, CP.5
  • 31
    • 75449088414 scopus 로고    scopus 로고
    • Decreased survival of subjects with elevated liver function tests during a 28-year follow-up
    • Söderberg C, Stål P, Askling J, Glaumann H, Lindberg G, Marmur J, et al. Decreased survival of subjects with elevated liver function tests during a 28-year follow-up. Hepatology 2010;51:595–602. doi: 10.1002/hep.23314.
    • (2010) Hepatology , vol.51 , pp. 595-602
    • Söderberg, C1    Stål, P2    Askling, J3    Glaumann, H4    Lindberg, G5    Marmur, J6
  • 32
    • 72949097025 scopus 로고    scopus 로고
    • Ultra-sonographic hepatic steatosis increases prediction of mortality risk from elevated serum gamma-glutamyl transpeptidase levels
    • Haring R, Wallaschofski H, Nauck M, Dörr M, Baumeister SE, Völzke H. Ultra-sonographic hepatic steatosis increases prediction of mortality risk from elevated serum gamma-glutamyl transpeptidase levels. Hepatology 2009;50: 1403–1411. doi: 10.1002/hep.23135.
    • (2009) Hepatology , vol.50 , pp. 1403-1411
    • Haring, R1    Wallaschofski, H2    Nauck, M3    Dörr, M4    Baumeister, SE5    Völzke, H.6
  • 33
    • 76149092159 scopus 로고    scopus 로고
    • Fatty liver predicts impaired fasting glucose and type 2 diabetes mellitus in Japanese undergoing a health checkup
    • Yamada T, Fukatsu M, Suzuki S, Wada T, Yoshida T, Joh T. Fatty liver predicts impaired fasting glucose and type 2 diabetes mellitus in Japanese undergoing a health checkup. J Gastroenterol Hepatol 2010;25:352–356. doi: 10.1111/j.1440-1746.2009.05998.x.
    • (2010) J Gastroenterol Hepatol , vol.25 , pp. 352-356
    • Yamada, T1    Fukatsu, M2    Suzuki, S3    Wada, T4    Yoshida, T5    Joh, T.6
  • 34
    • 65349101599 scopus 로고    scopus 로고
    • Alanine aminotransferase, gamma-glutamyltransferase, and incident diabetes: the British Women’s Heart and Health Study and meta-analysis
    • Fraser A, Harris R, Sattar N, Ebrahim S, Davey Smith G, Lawlor DA. Alanine aminotransferase, gamma-glutamyltransferase, and incident diabetes: the British Women’s Heart and Health Study and meta-analysis. Diabetes Care 2009;32:741–750. doi: 10.2337/dc08-1870.
    • (2009) Diabetes Care , vol.32 , pp. 741-750
    • Fraser, A1    Harris, R2    Sattar, N3    Ebrahim, S4    Davey Smith, G5    Lawlor, DA.6
  • 35
    • 80053574709 scopus 로고    scopus 로고
    • Risk of all-cause and cardiovascular mortality in patients with chronic liver disease
    • author reply 1603–1604
    • Targher G, Zoppini G, Day CP. Risk of all-cause and cardiovascular mortality in patients with chronic liver disease. Gut 2011;60:1602–1603; author reply 1603–1604. doi: 10.1136/gut.2010.230656.
    • (2011) Gut , vol.60 , pp. 1602-1603
    • Targher, G1    Zoppini, G2    Day, CP.3
  • 36
    • 84861197159 scopus 로고    scopus 로고
    • Hepatocellular carcinoma in non-alcoholic fatty liver disease: an emerging menace
    • Baffy G, Brunt EM, Caldwell SH. Hepatocellular carcinoma in non-alcoholic fatty liver disease: an emerging menace. J Hepatol 2012;56:1384–1391. doi: 10.1016/j.jhep.2011.10.027.
    • (2012) J Hepatol , vol.56 , pp. 1384-1391
    • Baffy, G1    Brunt, EM2    Caldwell, SH.3
  • 38
    • 0025186310 scopus 로고
    • Effect of weight reduction on hepatic abnormalities in overweight patients
    • Palmer M, Schaffner F. Effect of weight reduction on hepatic abnormalities in overweight patients. Gastroenterology 1990;99:1408–1413.
    • (1990) Gastroenterology , vol.99 , pp. 1408-1413
    • Palmer, M1    Schaffner, F.2
  • 39
    • 0030740659 scopus 로고    scopus 로고
    • Therapeutic effects of restricted diet and exercise in obese patients with fatty liver
    • Ueno T, Sugawara H, Sujaku K, Hashimoto O, Tsuji R, Tamaki S, et al. Therapeutic effects of restricted diet and exercise in obese patients with fatty liver. J Hepatol 1997;27:103–107. doi: 10.1016/S0168-8278(97)80287-5.
    • (1997) J Hepatol , vol.27 , pp. 103-107
    • Ueno, T1    Sugawara, H2    Sujaku, K3    Hashimoto, O4    Tsuji, R5    Tamaki, S6
  • 40
    • 33745018473 scopus 로고    scopus 로고
    • Change in liver size and fat content after treatment with Optifast very low calorie diet
    • Lewis MC, Phillips ML, Slavotinek JP, Kow L, Thompson CH, Toouli J. Change in liver size and fat content after treatment with Optifast very low calorie diet. Obes Surg 2006;16:697–701. doi: 10.1381/096089206777346682.
    • (2006) Obes Surg , vol.16 , pp. 697-701
    • Lewis, MC1    Phillips, ML2    Slavotinek, JP3    Kow, L4    Thompson, CH5    Toouli, J.6
  • 41
    • 72449161164 scopus 로고    scopus 로고
    • Diet and exercise interventions reduce intrahepatic fat content and improve insulin sensitivity in obese older adults
    • Shah K, Stufflebam A, Hilton TN, Sinacore DR, Klein S, Villareal DT. Diet and exercise interventions reduce intrahepatic fat content and improve insulin sensitivity in obese older adults. Obesity (Silver Spring) 2009;17:2162– 2168. doi: 10.1038/oby.2009.126.
    • (2009) Obesity (Silver Spring) , vol.17 , pp. 2162-2168
    • Shah, K1    Stufflebam, A2    Hilton, TN3    Sinacore, DR4    Klein, S5    Villareal, DT.6
  • 42
    • 78149283488 scopus 로고    scopus 로고
    • Effect of a 12-month intensive lifestyle intervention on hepatic steatosis in adults with type 2 diabetes
    • Lazo M, Solga SF, Horska A, Bonekamp S, Diehl AM, Brancati FL, et al. Effect of a 12-month intensive lifestyle intervention on hepatic steatosis in adults with type 2 diabetes. Diabetes Care 2010;33:2156–2163. doi: 10.2337/dc10-0856.
    • (2010) Diabetes Care , vol.33 , pp. 2156-2163
    • Lazo, M1    Solga, SF2    Horska, A3    Bonekamp, S4    Diehl, AM5    Brancati, FL6
  • 43
    • 84867200413 scopus 로고    scopus 로고
    • Relationship between adipose tissue insulin resistance and liver histology in nonalcoholic steatohepatitis: a pioglitazone versus vitamin E versus placebo for the treatment of nondiabetic patients with nonalcoholic steatohepatitis trial follow-up study
    • Bell LN, Wang J, Muralidharan S, Chalasani S, Fullenkamp AM, Wilson LA, et al. Relationship between adipose tissue insulin resistance and liver histology in nonalcoholic steatohepatitis: a pioglitazone versus vitamin E versus placebo for the treatment of nondiabetic patients with nonalcoholic steatohepatitis trial follow-up study. Hepatology 2012;56:1311–1318. doi: 10.1002/hep.25805.
    • (2012) Hepatology , vol.56 , pp. 1311-1318
    • Bell, LN1    Wang, J2    Muralidharan, S3    Chalasani, S4    Fullenkamp, AM5    Wilson, LA6
  • 44
    • 84882811171 scopus 로고    scopus 로고
    • Community-based lifestyle modification programme for non-alcoholic fatty liver disease: a randomized controlled trial
    • Wong VW, Chan RS, Wong GL, Cheung BH, Chu WC, Yeung DK, et al. Community-based lifestyle modification programme for non-alcoholic fatty liver disease: a randomized controlled trial. J Hepatol 2013;59:536–542. doi: 10.1016/j.jhep.2013.04.013.
    • (2013) J Hepatol , vol.59 , pp. 536-542
    • Wong, VW1    Chan, RS2    Wong, GL3    Cheung, BH4    Chu, WC5    Yeung, DK6
  • 45
    • 83555176039 scopus 로고    scopus 로고
    • Lifestyle interventions for the treatment of nonalcoholic fatty liver disease in adults: a systematic review
    • Thoma C, Day CP, Trenell MI. Lifestyle interventions for the treatment of nonalcoholic fatty liver disease in adults: a systematic review. J Hepatol 2012; 56:255–266. doi: 10.1016/j.jhep.2011.06.010.
    • (2012) J Hepatol , vol.56 , pp. 255-266
    • Thoma, C1    Day, CP2    Trenell, MI.3
  • 46
    • 84895508097 scopus 로고    scopus 로고
    • Diets and nonalcoholic fatty liver disease: the good and the bad
    • Asrih M, Jornayvaz FR. Diets and nonalcoholic fatty liver disease: the good and the bad. Clin Nutr 2014. 33:186–190. doi: 10.1016/j.clnu.2013.11.003.
    • (2014) Clin Nutr , vol.33 , pp. 186-190
    • Asrih, M1    Jornayvaz, FR.2
  • 47
    • 84888018704 scopus 로고    scopus 로고
    • The role of diet and nutritional intervention for the management of patients with NAFLD
    • Barrera F, George J. The role of diet and nutritional intervention for the management of patients with NAFLD. Clin Liver Dis 2014;18:91–112. doi: 10.1016/j.cld.2013.09.009.
    • (2014) Clin Liver Dis , vol.18 , pp. 91-112
    • Barrera, F1    George, J.2
  • 48
    • 61449183682 scopus 로고    scopus 로고
    • Comparison of weight-loss diets with different compositions of fat, protein, and carbohydrates
    • Sacks FM, Bray GA, Carey VJ, Smith SR, Ryan DH, Anton SD, et al. Comparison of weight-loss diets with different compositions of fat, protein, and carbohydrates. N Engl J Med 2009;360:859–873. doi: 10.1056/NEJMoa0804748.
    • (2009) N Engl J Med , vol.360 , pp. 859-873
    • Sacks, FM1    Bray, GA2    Carey, VJ3    Smith, SR4    Ryan, DH5    Anton, SD6
  • 49
    • 79960442493 scopus 로고    scopus 로고
    • The effect of the Spanish Ketogenic Mediterranean Diet on nonalcoholic fatty liver disease: a pilot study
    • Pérez-Guisado J, Muñoz-Serrano A. The effect of the Spanish Ketogenic Mediterranean Diet on nonalcoholic fatty liver disease: a pilot study. J Med Food 2011;14:677–680. doi: 10.1089/jmf.2011.0075.
    • (2011) J Med Food , vol.14 , pp. 677-680
    • Pérez-Guisado, J1    Muñoz-Serrano, A.2
  • 50
    • 47549110641 scopus 로고    scopus 로고
    • Weight loss with a low-carbohydrate, Mediterranean, or low-fat diet
    • Promrat K, Kleiner DE, Niemeier HM, Jackvony E, Kearns M, Wands JR, et al. Weight loss with a low-carbohydrate, Mediterranean, or low-fat diet. N Engl J Med 2008;359:229–241. doi: 10.1056/NEJMoa0708681.
    • (2008) N Engl J Med , vol.359 , pp. 229-241
    • Promrat, K1    Kleiner, DE2    Niemeier, HM3    Jackvony, E4    Kearns, M5    Wands, JR6
  • 51
    • 73449116035 scopus 로고    scopus 로고
    • Randomized controlled trial testing the effects of weight loss on nonalcoholic steatohepatitis
    • Promrat K, Kleiner DE, Niemeier HM, Jackvony E, Kearns M, Wands JR, et al. Randomized controlled trial testing the effects of weight loss on nonalcoholic steatohepatitis. Hepatology 2010;51:121–129. doi: 10.1002/hep.23276.
    • (2010) Hepatology , vol.51 , pp. 121-129
    • Promrat, K1    Kleiner, DE2    Niemeier, HM3    Jackvony, E4    Kearns, M5    Wands, JR6
  • 53
    • 70449517253 scopus 로고    scopus 로고
    • 10-year follow-up of diabetes incidence and weight loss in the Diabetes Prevention Program Outcomes Study
    • Diabets prevention program research group, Diabetes Prevention Program Research Group
    • Diabets prevention program research group, Knowler WC, Fowler SE, Hamman RF, Christophi CA, Hoffman HJ, et al. Diabetes Prevention Program Research Group. 10-year follow-up of diabetes incidence and weight loss in the Diabetes Prevention Program Outcomes Study. Lancet 2009;374: 677–686. doi: 10.1016/S0140-6736(09)61457-4.
    • (2009) Lancet , vol.374 , pp. 677-686
    • Knowler, WC1    Fowler, SE2    Hamman, RF3    Christophi, CA4    Hoffman, HJ5
  • 54
    • 77949270804 scopus 로고    scopus 로고
    • Adherence is a multi-dimensional construct in the POUNDS LOST trial
    • Williamson DA, Anton SD, Han H, Champagne CM, Allen R, LeBlanc E, et al. Adherence is a multi-dimensional construct in the POUNDS LOST trial. J Behav Med 2010;33:35–46. doi: 10.1007/s10865-009-9230-7.
    • (2010) J Behav Med , vol.33 , pp. 35-46
    • Williamson, DA1    Anton, SD2    Han, H3    Champagne, CM4    Allen, R5    LeBlanc, E6
  • 55
    • 84922322588 scopus 로고    scopus 로고
    • Orthotopic liver transplantation in non-alcoholic fatty liver disease patients
    • Burra P, Germani G. Orthotopic liver transplantation in non-alcoholic fatty liver disease patients. Rev Recent Clin Trials 2014;9:210–216. doi: 10. 2174/1574887109666141216105224.
    • (2014) Rev Recent Clin Trials , vol.9 , pp. 210-216
    • Burra, P1    Germani, G.2
  • 56
    • 85041823681 scopus 로고    scopus 로고
    • Drugs improving insulin resistance for non-alcoholic fatty liver disease and/or non-alcoholic steatohepatitis
    • Angelico F, Burattin M, Alessandri C, Del Ben M, Lirussi F. Drugs improving insulin resistance for non-alcoholic fatty liver disease and/or non-alcoholic steatohepatitis. Cochrane Database Syst Rev 2007;1:CD005166. doi: 10. 1002/14651858.CD005166.pub2.
    • (2007) Cochrane Database Syst Rev , vol.1 , pp. CD005166
    • Angelico, F1    Burattin, M2    Alessandri, C3    Del Ben, M4    Lirussi, F.5
  • 57
    • 80051791560 scopus 로고    scopus 로고
    • Treatment with insulin sensitizer metformin improves arterial properties, metabolic parameters, and liver function in patients with nonalcoholic fatty liver disease: a random-ized, placebo-controlled trial
    • Sofer E, Boaz M, Matas Z, Mashavi M, Shargorodsky M. Treatment with insulin sensitizer metformin improves arterial properties, metabolic parameters, and liver function in patients with nonalcoholic fatty liver disease: a random-ized, placebo-controlled trial. Metabolism 2011;60:1278–1284. doi: 10. 1016/j.metabol.2011.01.011.
    • (2011) Metabolism , vol.60 , pp. 1278-1284
    • Sofer, E1    Boaz, M2    Matas, Z3    Mashavi, M4    Shargorodsky, M.5
  • 58
    • 58949102847 scopus 로고    scopus 로고
    • Orlistat for overweight subjects with nonalcoholic steatohepatitis: A randomized, prospective trial
    • Harrison SA, Fecht W, Brunt EM, Neuschwander-Tetri BA. Orlistat for overweight subjects with nonalcoholic steatohepatitis: A randomized, prospective trial. Hepatology 2009;49:80–86. doi: 10.1002/hep.22575.
    • (2009) Hepatology , vol.49 , pp. 80-86
    • Harrison, SA1    Fecht, W2    Brunt, EM3    Neuschwander-Tetri, BA.4
  • 59
    • 80055028155 scopus 로고    scopus 로고
    • Pentox-ifylline improves nonalcoholic steatohepatitis: a randomized placebo-controlled trial
    • Zein CO, Yerian LM, Gogate P, Lopez R, Kirwan JP, Feldstein AE, et al. Pentox-ifylline improves nonalcoholic steatohepatitis: a randomized placebo-controlled trial. Hepatology 2011;54:1610–1619. doi: 10.1002/hep.24544.
    • (2011) Hepatology , vol.54 , pp. 1610-1619
    • Zein, CO1    Yerian, LM2    Gogate, P3    Lopez, R4    Kirwan, JP5    Feldstein, AE6
  • 60
    • 85179144562 scopus 로고    scopus 로고
    • Liraglutide is effective in the histological clearance of nonalcoholic steatohepatitis in a multicentre, double-blinded, randomised, placebo-controlled phase II trial
    • Vienna, Austria
    • Armstrong MJ. Liraglutide is effective in the histological clearance of nonalcoholic steatohepatitis in a multicentre, double-blinded, randomised, placebo-controlled phase II trial. In: International Liver Congress, Vienna, Austria, 2015.
    • (2015) International Liver Congress
    • Armstrong, MJ.1
  • 61
    • 84888119563 scopus 로고    scopus 로고
    • Liraglutide efficacy and action in non-alcoholic steatohepatitis (LEAN): study protocol for a phase II multicentre, double-blinded, randomised, controlled trial
    • Armstrong MJ, Barton D, Gaunt P, Hull D, Guo K, Stocken D, et al. Liraglutide efficacy and action in non-alcoholic steatohepatitis (LEAN): study protocol for a phase II multicentre, double-blinded, randomised, controlled trial. BMJ Open 2013;3:e003995. doi: 10.1136/bmjopen-2013-003995.
    • (2013) BMJ Open , vol.3 , pp. e003995
    • Armstrong, MJ1    Barton, D2    Gaunt, P3    Hull, D4    Guo, K5    Stocken, D6
  • 62
    • 80052102126 scopus 로고    scopus 로고
    • Weight reduction for non-alcoholic fatty liver disease
    • Peng L, Wang J, Li F. Weight reduction for non-alcoholic fatty liver disease. Cochrane Database Syst Rev 2011:CD003619. doi: 10.1002/14651858. CD003619.pub3.
    • (2011) Cochrane Database Syst Rev , pp. CD003619
    • Peng, L1    Wang, J2    Li, F.3
  • 63
    • 1642479937 scopus 로고    scopus 로고
    • The importance of routine liver biopsy in diagnosing nonalcoholic stea-tohepatitis in bariatric patients
    • Shalhub S, Parsee A, Gallagher SF, Haines KL, Willkomm C, Brantley SG, et al. The importance of routine liver biopsy in diagnosing nonalcoholic stea-tohepatitis in bariatric patients. Obes Surg 2004;14:54–59. doi: 10.1381/096089204772787293
    • (2004) Obes Surg , vol.14 , pp. 54-59
    • Shalhub, S1    Parsee, A2    Gallagher, SF3    Haines, KL4    Willkomm, C5    Brantley, SG6
  • 64
    • 84899652361 scopus 로고    scopus 로고
    • Hepatic pathology among patients without known liver disease undergoing bariatric surgery: observations and a perspective from the longitudinal assessment of bariatric surgery (LABS) study
    • Kleiner DE, Berk PD, Hsu JY, Courcoulas AP, Flum D, Khandelwal S, et al. Hepatic pathology among patients without known liver disease undergoing bariatric surgery: observations and a perspective from the longitudinal assessment of bariatric surgery (LABS) study. Semin Liver Dis 2014;34: 98–107. doi: 10.1055/s-0034-1371083.
    • (2014) Semin Liver Dis , vol.34 , pp. 98-107
    • Kleiner, DE1    Berk, PD2    Hsu, JY3    Courcoulas, AP4    Flum, D5    Khandelwal, S6
  • 65
    • 84874597977 scopus 로고    scopus 로고
    • Bariatric surgery as potential treatment for nonalcoholic fatty liver disease: a future treatment by choice or by chance?
    • Hafeez S, Ahmed MH. Bariatric surgery as potential treatment for nonalcoholic fatty liver disease: a future treatment by choice or by chance? J Obes 2013;2013:839275. doi: 10.1155/2013/839275.
    • (2013) J Obes , vol.2013 , pp. 839275
    • Hafeez, S1    Ahmed, MH.2
  • 66
    • 84857946710 scopus 로고    scopus 로고
    • The impact of bariatric surgery on nonalcoholic steato-hepatitis
    • Rabl C, Campos GM. The impact of bariatric surgery on nonalcoholic steato-hepatitis. Semin Liver Dis 2012;32:80–91. doi: 10.1055/s-0032-1306428.
    • (2012) Semin Liver Dis , vol.32 , pp. 80-91
    • Rabl, C1    Campos, GM.2
  • 68
    • 84925495884 scopus 로고    scopus 로고
    • Bariatric surgery improves histological features of nonalcoholic Fatty liver disease and liver fibrosis
    • Taitano AA, Markow M, Finan JE, Wheeler DE, Gonzalvo JP, Murr MM. Bariatric surgery improves histological features of nonalcoholic Fatty liver disease and liver fibrosis. J Gastrointest Surg 2015;19:429–437. doi: 10.1007/s11605-014-2678-y.
    • (2015) J Gastrointest Surg , vol.19 , pp. 429-437
    • Taitano, AA1    Markow, M2    Finan, JE3    Wheeler, DE4    Gonzalvo, JP5    Murr, MM.6
  • 69
    • 84939995168 scopus 로고    scopus 로고
    • Effect of Roux-en-y Gastric Bypass on Nonalcoholic Fatty Liver Disease Evaluated Through NAFLD Fibrosis Score: a Prospective Study
    • Cazzo E, Jimenez LS, Pareja JC, Chaim EA. Effect of Roux-en-y Gastric Bypass on Nonalcoholic Fatty Liver Disease Evaluated Through NAFLD Fibrosis Score: a Prospective Study. Obes Surg 2015;25:982–985. doi: 10.1007/s11695-014-1489-2.
    • (2015) Obes Surg , vol.25 , pp. 982-985
    • Cazzo, E1    Jimenez, LS2    Pareja, JC3    Chaim, EA.4
  • 70
    • 2542546652 scopus 로고    scopus 로고
    • Nonalcoholic fatty liver disease: Improvement in liver histological analysis with weight loss
    • Dixon JB, Bhathal PS, Hughes NR, O’Brien PE. Nonalcoholic fatty liver disease: Improvement in liver histological analysis with weight loss. Hepa-tology 2004;39:1647–1654. doi: 10.1002/hep.20251.
    • (2004) Hepa-tology , vol.39 , pp. 1647-1654
    • Dixon, JB1    Bhathal, PS2    Hughes, NR3    O’Brien, PE.4
  • 71
    • 80053291979 scopus 로고    scopus 로고
    • Influence of Sleeve Gastrectomy on NASH and Type 2 Diabetes Mellitus
    • Karcz WK, Krawczykowski D, Kuesters S, Marjanovic G, Kulemann B, Grobe H, et al. Influence of Sleeve Gastrectomy on NASH and Type 2 Diabetes Mellitus. J Obes 2011;2011:765473. doi: 10.1155/2011/765473.
    • (2011) J Obes , vol.2011 , pp. 765473
    • Karcz, WK1    Krawczykowski, D2    Kuesters, S3    Marjanovic, G4    Kulemann, B5    Grobe, H6
  • 72
    • 0348047323 scopus 로고    scopus 로고
    • Effects of surgical treatment of the metabolic syndrome on liver fibrosis and cirrhosis
    • Kral JG, Thung SN, Biron S, Hould FS, Lebel S, Marceau S, et al. Effects of surgical treatment of the metabolic syndrome on liver fibrosis and cirrhosis. Surgery 2004;135:48–58. doi: 10.1016/j.surg.2003.10.003.
    • (2004) Surgery , vol.135 , pp. 48-58
    • Kral, JG1    Thung, SN2    Biron, S3    Hould, FS4    Lebel, S5    Marceau, S6
  • 73
    • 28544448787 scopus 로고    scopus 로고
    • Duodenal switch has no detrimental effects on hepatic function and improves hepatic steatohepatitis after 6 months
    • Keshishian A, Zahriya K, Willes EB. Duodenal switch has no detrimental effects on hepatic function and improves hepatic steatohepatitis after 6 months. Obes Surg 2005;15:1418–1423. doi: 10.1381/096089205774859290.
    • (2005) Obes Surg , vol.15 , pp. 1418-1423
    • Keshishian, A1    Zahriya, K2    Willes, EB.3
  • 74
    • 67650951419 scopus 로고    scopus 로고
    • Prospective study of the long-term effects of bariatric surgery on liver injury in patients without advanced disease
    • Mathurin P, Hollebecque A, Arnalsteen L, Buob D, Leteurtre E, Caiazzo R, et al. Prospective study of the long-term effects of bariatric surgery on liver injury in patients without advanced disease. Gastroenterology 2009;137: 532–540. doi: 10.1053/j.gastro.2009.04.052.
    • (2009) Gastroenterology , vol.137 , pp. 532-540
    • Mathurin, P1    Hollebecque, A2    Arnalsteen, L3    Buob, D4    Leteurtre, E5    Caiazzo, R6
  • 75
    • 33750606061 scopus 로고    scopus 로고
    • Long-term follow-up of patients with NAFLD and elevated liver enzymes
    • Ekstedt M, Franzén LE, Mathiesen UL, Thorelius L, Holmqvist M, Bodemar G, et al. Long-term follow-up of patients with NAFLD and elevated liver enzymes. Hepatology 2006;44:865–873. doi: 10.1002/hep.21327.
    • (2006) Hepatology , vol.44 , pp. 865-873
    • Ekstedt, M1    Franzén, LE2    Mathiesen, UL3    Thorelius, L4    Holmqvist, M5    Bodemar, G6
  • 76
    • 11144351102 scopus 로고    scopus 로고
    • The histological course of nonalcoholic fatty liver disease: a longitudinal study of 103 patients with sequential liver biopsies
    • Adams LA, Sanderson S, Lindor KD, Angulo P. The histological course of nonalcoholic fatty liver disease: a longitudinal study of 103 patients with sequential liver biopsies. J Hepatol 2005;42:132–138. doi: 10.1016/j.jhep.2004. 09.012.
    • (2005) J Hepatol , vol.42 , pp. 132-138
    • Adams, LA1    Sanderson, S2    Lindor, KD3    Angulo, P.4
  • 77
    • 84875436214 scopus 로고    scopus 로고
    • Long-term effect of bariatric surgery on liver enzymes in the Swedish Obese Subjects (SOS) study
    • Burza MA, Romeo S, Kotronen A, Svensson PA, Sjöholm K, Torgerson JS, et al. Long-term effect of bariatric surgery on liver enzymes in the Swedish Obese Subjects (SOS) study. PLoS One 2013;8:e60495. doi: 10.1371/journal.pone.0060495.
    • (2013) PLoS One , vol.8 , pp. e60495
    • Burza, MA1    Romeo, S2    Kotronen, A3    Svensson, PA4    Sjöholm, K5    Torgerson, JS6
  • 78
    • 79955731616 scopus 로고    scopus 로고
    • Current status of endoluminal bariatric procedures for primary and revision indications
    • Ryou M, Ryan MB, Thompson CC. Current status of endoluminal bariatric procedures for primary and revision indications. Gastrointest Endosc Clin N Am 2011;21:315–333. doi: 10.1016/j.giec.2011.02.004.
    • (2011) Gastrointest Endosc Clin N Am , vol.21 , pp. 315-333
    • Ryou, M1    Ryan, MB2    Thompson, CC.3
  • 79
    • 85179147506 scopus 로고    scopus 로고
    • Intragastric balloon as a treatment for nonalcoholic fatty liver disease in adults: a systematic review and meta-anal-ysis
    • Boston, Massachusetts, USA, November
    • Popov V, Kumar N, Thompson CC. Intragastric balloon as a treatment for nonalcoholic fatty liver disease in adults: a systematic review and meta-anal-ysis. In: Obesity Week, Boston, Massachusetts, USA, November 2014.
    • (2014) Obesity Week
    • Popov, V1    Kumar, N2    Thompson, CC.3
  • 80
    • 84866381665 scopus 로고    scopus 로고
    • Intragastric balloon significantly improves nonalcoholic fatty liver disease activity score in obese patients with nonalcoholic steatohepatitis: a pilot study
    • Lee YM, Low HC, Lim LG, Dan YY, Aung MO, Cheng CL, et al. Intragastric balloon significantly improves nonalcoholic fatty liver disease activity score in obese patients with nonalcoholic steatohepatitis: a pilot study. Gastroint-est Endosc 2012;76:756–760. doi: 10.1016/j.gie.2012.05.023.
    • (2012) Gastroint-est Endosc , vol.76 , pp. 756-760
    • Lee, YM1    Low, HC2    Lim, LG3    Dan, YY4    Aung, MO5    Cheng, CL6
  • 82
    • 84885871395 scopus 로고    scopus 로고
    • Endoscopic duodenal-jejunal bypass liner rapidly improves plasma parameters of nonalcoholic fatty liver disease
    • de Jonge C, Rensen SS, Koek GH, Joosten MF, Buurman WA, Bouvy ND, et al. Endoscopic duodenal-jejunal bypass liner rapidly improves plasma parameters of nonalcoholic fatty liver disease. Clin Gastroenterol Hepatol 2013;11: 1517–1520. doi: 10.1016/j.cgh.2013.07.029.
    • (2013) Clin Gastroenterol Hepatol , vol.11 , pp. 1517-1520
    • de Jonge, C1    Rensen, SS2    Koek, GH3    Joosten, MF4    Buurman, WA5    Bouvy, ND6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.