Methylglyoxal-induced endothelial cell loss and inflammation contribute to the development of diabetic cardiomyopathy

Diabetes

Volumn 65, Issue 6, 2016, Pages 1699-1713

  Vulesevic, Branka ^a,b   McNeill, Brian ^a   Giacco, Ferdinando ^c   Maeda, Kay ^a   Blackburn, Nick J R ^a,b   Brownlee, Michael ^c   Milne, Ross W ^a   Suuronen, Erik J ^a,b  

^a UNIVERSITY OF OTTAWA HEART INSTITUTE   (Canada)

^b UNIVERSITY OF OTTAWA   (Canada)

^c ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADVANCED GLYCATION END PRODUCT RECEPTOR; ANGIOPOIETIN 2; ENDOTHELIAL NITRIC OXIDE SYNTHASE; GLYOXALASE; GLYOXALASE 1; METHYLGLYOXAL; NEU DIFFERENTIATION FACTOR; PROTEIN BCL 2; STREPTOZOCIN; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; ADVANCED GLYCATION END PRODUCT; LACTOYLGLUTATHIONE LYASE; TUMOR NECROSIS FACTOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CAPILLARY DENSITY; CARDIAC MUSCLE CELL; CELL COUNT; CELL DEATH; CELL LOSS; CONTROLLED STUDY; DIABETIC CARDIOMYOPATHY; DIMERIZATION; ENDOTHELIAL DYSFUNCTION; ENDOTHELIUM CELL; GENE OVEREXPRESSION; HEART VENTRICLE FAILURE; HYPERGLYCEMIA; IN VITRO STUDY; MACROPHAGE; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; STREPTOZOTOCIN-INDUCED DIABETES MELLITUS; VASCULARIZATION; ANIMAL; C57BL MOUSE; CARDIAC MUSCLE; CASE CONTROL STUDY; COMPLICATION; DIABETIC CARDIOMYOPATHIES; EXPERIMENTAL DIABETES MELLITUS; METABOLISM; MYOCARDITIS; PATHOLOGY; PROTO ONCOGENE;

ANGIOPOIETIN-2; ANIMALS; CASE-CONTROL STUDIES; CELL DEATH; DIABETES MELLITUS, EXPERIMENTAL; DIABETIC CARDIOMYOPATHIES; ENDOTHELIAL CELLS; GENES, BCL-2; GLYCOSYLATION END PRODUCTS, ADVANCED; LACTOYLGLUTATHIONE LYASE; MACROPHAGES; MICE; MICE, INBRED C57BL; MYOCARDITIS; MYOCARDIUM; PYRUVALDEHYDE; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84969856023     PISSN: 00121797     EISSN: 1939327X     Source Type: Journal    
DOI: 10.2337/db15-0568     Document Type: Article

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