Mechanism of Human Nucleocytoplasmic Hexosaminidase D

Biochemistry

Volumn 55, Issue 19, 2016, Pages 2735-2747

  Alteen, Matthew G ^a,b   Oehler, Verena ^b   Nemčovičová, Ivana ^c,d   Wilson, Iain B H ^c   Vocadlo, David J ^a   Gloster, Tracey M ^b  

^a SIMON FRASER UNIVERSITY   (Canada)

^b UNIVERSITY OF ST ANDREWS   (United Kingdom)

^c UNIVERSITY OF NATURAL RESOURCES AND LIFE SCIENCES   (Austria)

^d Oddelenie glykobiotechnológie   (Slovakia)

Author keywords

[No Author keywords available]

Indexed keywords

CATALYSIS; FREE ENERGY; MAMMALS; PHYSIOLOGY; RATE CONSTANTS; SUBSTRATES;

CATALYTIC MECHANISMS; CELLULAR SUBSTRATES; LINEAR FREE-ENERGY ANALYSIS; MECHANISM OF ACTION; MECHANISTIC STUDIES; N-ACETYLGLUCOSAMINE; PHYSIOLOGICAL ROLES; SECOND-ORDER RATE CONSTANTS;

ENZYME INHIBITION;

BETA N ACETYLHEXOSAMINIDASE; GLUCOSAMINE DERIVATIVE; HEXOSAMINIDASE D; UNCLASSIFIED DRUG; ENZYME INHIBITOR; THIAZOLIDINE DERIVATIVE;

ARTICLE; CATALYSIS; ENZYME ACTIVITY; ENZYME ANALYSIS; ENZYME LOCALIZATION; ENZYME STRUCTURE; HYDROLYSIS; MOLECULAR DYNAMICS; NUCLEAR MAGNETIC RESONANCE; PH; POLARIZATION; PRIORITY JOURNAL; REACTION ANALYSIS; STEREOCHEMISTRY; ANTAGONISTS AND INHIBITORS; CHEMISTRY; GENETICS; HUMAN; KINETICS; METABOLISM;

CATALYSIS; ENZYME INHIBITORS; HEXOSAMINIDASES; HUMANS; HYDROGEN-ION CONCENTRATION; HYDROLYSIS; KINETICS; THIAZOLIDINES;

EID: 84969812041     PISSN: 00062960     EISSN: 15204995     Source Type: Journal    
DOI: 10.1021/acs.biochem.5b01285     Document Type: Article

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