메뉴 건너뛰기




Volumn 65, Issue 6, 2016, Pages 1577-1589

Disruption of adipose Rab10-dependent insulin signaling causes hepatic insulin resistance

Author keywords

[No Author keywords available]

Indexed keywords

GLUCOSE TRANSPORTER 4; INSULIN; RAB PROTEIN; RAB10 PROTEIN; UNCLASSIFIED DRUG; GLUCOSE; RAB10 PROTEIN, MOUSE;

EID: 84969749442     PISSN: 00121797     EISSN: 1939327X     Source Type: Journal    
DOI: 10.2337/db15-1128     Document Type: Article
Times cited : (41)

References (52)
  • 1
    • 0028321736 scopus 로고
    • Insulin-stimulated GLUT4 glucose transporter recycling. A problem in membrane protein subcellular trafficking through multiple pools
    • Holman GD, Lo Leggio L, Cushman SW. Insulin-stimulated GLUT4 glucose transporter recycling. A problem in membrane protein subcellular trafficking through multiple pools. J Biol Chem 1994;269:17516-17524
    • (1994) J Biol Chem , vol.269 , pp. 17516-17524
    • Holman, G.D.1    Lo Leggio, L.2    Cushman, S.W.3
  • 2
    • 0028876227 scopus 로고
    • Kinetic analysis of glucose transporter trafficking in fibroblasts and adipocytes
    • Yeh JI, Verhey KJ, Birnbaum MJ. Kinetic analysis of glucose transporter trafficking in fibroblasts and adipocytes. Biochemistry 1995;34:15523-15531
    • (1995) Biochemistry , vol.34 , pp. 15523-15531
    • Yeh, J.I.1    Verhey, K.J.2    Birnbaum, M.J.3
  • 3
    • 0742288016 scopus 로고    scopus 로고
    • GLUT4 is retained by an intracellular cycle of vesicle formation and fusion with endosomes
    • Karylowski O, Zeigerer A, Cohen A, McGraw TE. GLUT4 is retained by an intracellular cycle of vesicle formation and fusion with endosomes. Mol Biol Cell 2004;15:870-882
    • (2004) Mol Biol Cell , vol.15 , pp. 870-882
    • Karylowski, O.1    Zeigerer, A.2    Cohen, A.3    McGraw, T.E.4
  • 4
    • 0018820017 scopus 로고
    • Potential mechanism of insulin action on glucose transport in the isolated rat adipose cell. Apparent translocation of intracellular transport systems to the plasma membrane
    • Cushman SW, Wardzala LJ. Potential mechanism of insulin action on glucose transport in the isolated rat adipose cell. Apparent translocation of intracellular transport systems to the plasma membrane. J Biol Chem 1980;255:4758-4762
    • (1980) J Biol Chem , vol.255 , pp. 4758-4762
    • Cushman, S.W.1    Wardzala, L.J.2
  • 5
    • 0008385878 scopus 로고
    • Evidence that insulin causes translocation of glucose transport activity to the plasma membrane from an intracellular storage site
    • Suzuki K, Kono T. Evidence that insulin causes translocation of glucose transport activity to the plasma membrane from an intracellular storage site. Proc Natl Acad Sci U S A 1980;77:2542-2545
    • (1980) Proc Natl Acad Sci U S A , vol.77 , pp. 2542-2545
    • Suzuki, K.1    Kono, T.2
  • 6
    • 0033834248 scopus 로고    scopus 로고
    • Targeted disruption of the glucose transporter 4 selectively in muscle causes insulin resistance and glucose intolerance
    • Zisman A, Peroni OD, Abel ED, et al. Targeted disruption of the glucose transporter 4 selectively in muscle causes insulin resistance and glucose intolerance. Nat Med 2000;6:924-928
    • (2000) Nat Med , vol.6 , pp. 924-928
    • Zisman, A.1    Peroni, O.D.2    Abel, E.D.3
  • 7
    • 0035825643 scopus 로고    scopus 로고
    • Adipose-selective targeting of the GLUT4 gene impairs insulin action in muscle and liver
    • Abel ED, Peroni O, Kim JK, et al. Adipose-selective targeting of the GLUT4 gene impairs insulin action in muscle and liver. Nature 2001;409:729-733
    • (2001) Nature , vol.409 , pp. 729-733
    • Abel, E.D.1    Peroni, O.2    Kim, J.K.3
  • 9
    • 0030987889 scopus 로고    scopus 로고
    • High-fat feeding impairs insulin-stimulated GLUT4 recruitment via an early insulin-signaling defect
    • Zierath JR, Houseknecht KL, Gnudi L, Kahn BB. High-fat feeding impairs insulin-stimulated GLUT4 recruitment via an early insulin-signaling defect. Diabetes 1997;46:215-223
    • (1997) Diabetes , vol.46 , pp. 215-223
    • Zierath, J.R.1    Houseknecht, K.L.2    Gnudi, L.3    Kahn, B.B.4
  • 10
    • 0035191192 scopus 로고    scopus 로고
    • Adipocytes exhibit abnormal subcellular distribution and translocation of vesicles containing glucose transporter 4 and insulin-regulated aminopeptidase in type 2 diabetes mellitus: Implications regarding defects in vesicle trafficking
    • Maianu L, Keller SR, Garvey WT. Adipocytes exhibit abnormal subcellular distribution and translocation of vesicles containing glucose transporter 4 and insulin-regulated aminopeptidase in type 2 diabetes mellitus: implications regarding defects in vesicle trafficking. J Clin Endocrinol Metab 2001;86:5450-5456
    • (2001) J Clin Endocrinol Metab , vol.86 , pp. 5450-5456
    • Maianu, L.1    Keller, S.R.2    Garvey, W.T.3
  • 11
    • 28544435205 scopus 로고    scopus 로고
    • Full intracellular retention of GLUT4 requires AS160 Rab GTPase activating protein
    • Eguez L, Lee A, Chavez JA, et al. Full intracellular retention of GLUT4 requires AS160 Rab GTPase activating protein. Cell Metab 2005;2:263-272
    • (2005) Cell Metab , vol.2 , pp. 263-272
    • Eguez, L.1    Lee, A.2    Chavez, J.A.3
  • 12
    • 0037677096 scopus 로고    scopus 로고
    • Insulin-stimulated phosphorylation of a Rab GTPase-activating protein regulates GLUT4 translocation
    • Sano H, Kane S, Sano E, et al. Insulin-stimulated phosphorylation of a Rab GTPase-activating protein regulates GLUT4 translocation. J Biol Chem 2003;278:14599-14602
    • (2003) J Biol Chem , vol.278 , pp. 14599-14602
    • Sano, H.1    Kane, S.2    Sano, E.3
  • 13
    • 33947578085 scopus 로고    scopus 로고
    • Rab10, a target of the AS160 Rab GAP, is required for insulin-stimulated translocation of GLUT4 to the adipocyte plasma membrane
    • Sano H, Eguez L, Teruel MN, et al. Rab10, a target of the AS160 Rab GAP, is required for insulin-stimulated translocation of GLUT4 to the adipocyte plasma membrane. Cell Metab 2007;5:293-303
    • (2007) Cell Metab , vol.5 , pp. 293-303
    • Sano, H.1    Eguez, L.2    Teruel, M.N.3
  • 14
    • 27844528870 scopus 로고    scopus 로고
    • Characterization of the role of the Rab GTPase-activating protein AS160 in insulin-regulated GLUT4 trafficking
    • Larance M, Ramm G, Stöckli J, et al. Characterization of the role of the Rab GTPase-activating protein AS160 in insulin-regulated GLUT4 trafficking. J Biol Chem 2005;280:37803-37813
    • (2005) J Biol Chem , vol.280 , pp. 37803-37813
    • Larance, M.1    Ramm, G.2    Stöckli, J.3
  • 15
    • 84866347107 scopus 로고    scopus 로고
    • Rab10 and myosin-Va mediate insulin-stimulated GLUT4 storage vesicle translocation in adipocytes
    • Chen Y, Wang Y, Zhang J, et al. Rab10 and myosin-Va mediate insulin-stimulated GLUT4 storage vesicle translocation in adipocytes. J Cell Biol 2012;198:545-560
    • (2012) J Cell Biol , vol.198 , pp. 545-560
    • Chen, Y.1    Wang, Y.2    Zhang, J.3
  • 16
    • 0037151026 scopus 로고    scopus 로고
    • A method to identify serine kinase substrates. Akt phosphorylates a novel adipocyte protein with a Rab GTPase-activating protein (GAP) domain
    • Kane S, Sano H, Liu SC, et al. A method to identify serine kinase substrates. Akt phosphorylates a novel adipocyte protein with a Rab GTPase-activating protein (GAP) domain. J Biol Chem 2002;277:22115-22118
    • (2002) J Biol Chem , vol.277 , pp. 22115-22118
    • Kane, S.1    Sano, H.2    Liu, S.C.3
  • 17
    • 26844573782 scopus 로고    scopus 로고
    • AS160, the Akt substrate regulating GLUT4 translocation, has a functional Rab GTPase-activating protein domain
    • Mîinea CP, Sano H, Kane S, et al. AS160, the Akt substrate regulating GLUT4 translocation, has a functional Rab GTPase-activating protein domain. Biochem J 2005;391:87-93
    • (2005) Biochem J , vol.391 , pp. 87-93
    • Mîinea, C.P.1    Sano, H.2    Kane, S.3
  • 18
    • 1542285451 scopus 로고    scopus 로고
    • Biological studies of radiolabeled glucose analogues iodinated in positions 3, 4 or 6
    • Perret P, Ghezzi C, Ogier L, et al. Biological studies of radiolabeled glucose analogues iodinated in positions 3, 4 or 6. Nucl Med Biol 2004;31:241-250
    • (2004) Nucl Med Biol , vol.31 , pp. 241-250
    • Perret, P.1    Ghezzi, C.2    Ogier, L.3
  • 19
    • 84874607649 scopus 로고    scopus 로고
    • Cellular mechanism by which estradiol protects female ovariectomized mice from high-fat diet-induced hepatic and muscle insulin resistance
    • Camporez JP, Jornayvaz FR, Lee HY, et al. Cellular mechanism by which estradiol protects female ovariectomized mice from high-fat diet-induced hepatic and muscle insulin resistance. Endocrinology 2013;154:1021-1028
    • (2013) Endocrinology , vol.154 , pp. 1021-1028
    • Camporez, J.P.1    Jornayvaz, F.R.2    Lee, H.Y.3
  • 20
  • 21
    • 84928987900 scopus 로고    scopus 로고
    • HTSeq - A Python framework to work with high-throughput sequencing data
    • Anders S, Pyl PT, Huber W. HTSeq - a Python framework to work with high-throughput sequencing data. Bioinformatics 2015;31:166-169
    • (2015) Bioinformatics , vol.31 , pp. 166-169
    • Anders, S.1    Pyl, P.T.2    Huber, W.3
  • 22
    • 77952123055 scopus 로고    scopus 로고
    • Transcript assembly and quantification by RNA-Seq reveals unannotated transcripts and isoform switching during cell differentiation
    • Trapnell C, Williams BA, Pertea G, et al. Transcript assembly and quantification by RNA-Seq reveals unannotated transcripts and isoform switching during cell differentiation. Nat Biotechnol 2010;28:511-515
    • (2010) Nat Biotechnol , vol.28 , pp. 511-515
    • Trapnell, C.1    Williams, B.A.2    Pertea, G.3
  • 23
    • 84926507971 scopus 로고    scopus 로고
    • Limma powers differential expression analyses for RNA-sequencing and microarray studies
    • Ritchie ME, Phipson B, Wu D, et al. limma powers differential expression analyses for RNA-sequencing and microarray studies. Nucleic Acids Res 2015;43:e47
    • (2015) Nucleic Acids Res , vol.43 , pp. e47
    • Ritchie, M.E.1    Phipson, B.2    Wu, D.3
  • 24
    • 27344435774 scopus 로고    scopus 로고
    • Gene set enrichment analysis: A knowledge-based approach for interpreting genome-wide expression profiles
    • Subramanian A, Tamayo P, Mootha VK, et al. Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles. Proc Natl Acad Sci U S A 2005;102:15545-15550
    • (2005) Proc Natl Acad Sci U S A , vol.102 , pp. 15545-15550
    • Subramanian, A.1    Tamayo, P.2    Mootha, V.K.3
  • 25
    • 79952155359 scopus 로고    scopus 로고
    • Transcriptional control of adipose lipid handling by IRF4
    • Eguchi J, Wang X, Yu S, et al. Transcriptional control of adipose lipid handling by IRF4. Cell Metab 2011;13:249-259
    • (2011) Cell Metab , vol.13 , pp. 249-259
    • Eguchi, J.1    Wang, X.2    Yu, S.3
  • 26
    • 84929962595 scopus 로고    scopus 로고
    • Targeted disruption of Rab10 causes early embryonic lethality
    • Lv P, Sheng Y, Zhao Z, et al. Targeted disruption of Rab10 causes early embryonic lethality. Protein Cell 2015;6:463-467
    • (2015) Protein Cell , vol.6 , pp. 463-467
    • Lv, P.1    Sheng, Y.2    Zhao, Z.3
  • 27
    • 55249098126 scopus 로고    scopus 로고
    • GLUT4 vesicle recruitment and fusion are differentially regulated by Rac, AS160, and Rab8A in muscle cells
    • Randhawa VK, Ishikura S, Talior-Volodarsky I, et al. GLUT4 vesicle recruitment and fusion are differentially regulated by Rac, AS160, and Rab8A in muscle cells. J Biol Chem 2008;283:27208-27219
    • (2008) J Biol Chem , vol.283 , pp. 27208-27219
    • Randhawa, V.K.1    Ishikura, S.2    Talior-Volodarsky, I.3
  • 28
    • 0035929258 scopus 로고    scopus 로고
    • Insulin-regulated trafficking of dual-labeled glucose transporter 4 in primary rat adipose cells
    • Dawson K, Aviles-Hernandez A, Cushman SW, Malide D. Insulin-regulated trafficking of dual-labeled glucose transporter 4 in primary rat adipose cells. Biochem Biophys Res Commun 2001;287:445-454
    • (2001) Biochem Biophys Res Commun , vol.287 , pp. 445-454
    • Dawson, K.1    Aviles-Hernandez, A.2    Cushman, S.W.3    Malide, D.4
  • 29
    • 0035196362 scopus 로고    scopus 로고
    • Insulin-regulated release from the endosomal recycling compartment is regulated by budding of specialized vesicles
    • Lampson MA, Schmoranzer J, Zeigerer A, Simon SM, McGraw TE. Insulin-regulated release from the endosomal recycling compartment is regulated by budding of specialized vesicles. Mol Biol Cell 2001;12:3489-3501
    • (2001) Mol Biol Cell , vol.12 , pp. 3489-3501
    • Lampson, M.A.1    Schmoranzer, J.2    Zeigerer, A.3    Simon, S.M.4    McGraw, T.E.5
  • 30
    • 0036325425 scopus 로고    scopus 로고
    • GLUT4 retention in adipocytes requires two intracellular insulin-regulated transport steps
    • Zeigerer A, Lampson MA, Karylowski O, et al. GLUT4 retention in adipocytes requires two intracellular insulin-regulated transport steps. Mol Biol Cell 2002;13:2421-2435
    • (2002) Mol Biol Cell , vol.13 , pp. 2421-2435
    • Zeigerer, A.1    Lampson, M.A.2    Karylowski, O.3
  • 31
    • 0025772167 scopus 로고
    • Perilipin, a major hormonally regulated adipocyte-specific phosphoprotein associated with the periphery of lipid storage droplets
    • Greenberg AS, Egan JJ, Wek SA, Garty NB, Blanchette-Mackie EJ, Londos C. Perilipin, a major hormonally regulated adipocyte-specific phosphoprotein associated with the periphery of lipid storage droplets. J Biol Chem 1991;266:11341-11346
    • (1991) J Biol Chem , vol.266 , pp. 11341-11346
    • Greenberg, A.S.1    Egan, J.J.2    Wek, S.A.3    Garty, N.B.4    Blanchette-Mackie, E.J.5    Londos, C.6
  • 32
    • 0028787490 scopus 로고
    • A novel serum protein similar to C1q, produced exclusively in adipocytes
    • Scherer PE, Williams S, Fogliano M, Baldini G, Lodish HF. A novel serum protein similar to C1q, produced exclusively in adipocytes. J Biol Chem 1995;270:26746-26749
    • (1995) J Biol Chem , vol.270 , pp. 26746-26749
    • Scherer, P.E.1    Williams, S.2    Fogliano, M.3    Baldini, G.4    Lodish, H.F.5
  • 33
    • 44049087531 scopus 로고    scopus 로고
    • Inhibition of GLUT4 translocation by Tbc1d1, a Rab GTPase-activating protein abundant in skeletal muscle, is partially relieved by AMP-activated protein kinase activation
    • Chavez JA, Roach WG, Keller SR, Lane WS, Lienhard GE. Inhibition of GLUT4 translocation by Tbc1d1, a Rab GTPase-activating protein abundant in skeletal muscle, is partially relieved by AMP-activated protein kinase activation. J Biol Chem 2008;283:9187-9195
    • (2008) J Biol Chem , vol.283 , pp. 9187-9195
    • Chavez, J.A.1    Roach, W.G.2    Keller, S.R.3    Lane, W.S.4    Lienhard, G.E.5
  • 34
    • 84884745683 scopus 로고    scopus 로고
    • Insulin responsiveness of glucose transporter 4 in 3T3-L1 cells depends on the presence of sortilin
    • Huang G, Buckler-Pena D, Nauta T, et al. Insulin responsiveness of glucose transporter 4 in 3T3-L1 cells depends on the presence of sortilin. Mol Biol Cell 2013;24:3115-3122
    • (2013) Mol Biol Cell , vol.24 , pp. 3115-3122
    • Huang, G.1    Buckler-Pena, D.2    Nauta, T.3
  • 36
    • 0034881391 scopus 로고    scopus 로고
    • The adipocyte-secreted protein Acrp30 enhances hepatic insulin action
    • Berg AH, Combs TP, Du X, Brownlee M, Scherer PE. The adipocyte-secreted protein Acrp30 enhances hepatic insulin action. Nat Med 2001;7:947-953
    • (2001) Nat Med , vol.7 , pp. 947-953
    • Berg, A.H.1    Combs, T.P.2    Du, X.3    Brownlee, M.4    Scherer, P.E.5
  • 37
    • 22944434929 scopus 로고    scopus 로고
    • Serum retinol binding protein 4 contributes to insulin resistance in obesity and type 2 diabetes
    • Yang Q, Graham TE, Mody N, et al. Serum retinol binding protein 4 contributes to insulin resistance in obesity and type 2 diabetes. Nature 2005;436:356-362
    • (2005) Nature , vol.436 , pp. 356-362
    • Yang, Q.1    Graham, T.E.2    Mody, N.3
  • 38
    • 84859921736 scopus 로고    scopus 로고
    • A novel ChREBP isoform in adipose tissue regulates systemic glucose metabolism
    • Herman MA, Peroni OD, Villoria J, et al. A novel ChREBP isoform in adipose tissue regulates systemic glucose metabolism. Nature 2012;484:333-338
    • (2012) Nature , vol.484 , pp. 333-338
    • Herman, M.A.1    Peroni, O.D.2    Villoria, J.3
  • 39
    • 77951232682 scopus 로고    scopus 로고
    • Adipose tissue branched chain amino acid (BCAA) metabolism modulates circulating BCAA levels
    • Herman MA, She P, Peroni OD, Lynch CJ, Kahn BB. Adipose tissue branched chain amino acid (BCAA) metabolism modulates circulating BCAA levels. J Biol Chem 2010;285:11348-11356
    • (2010) J Biol Chem , vol.285 , pp. 11348-11356
    • Herman, M.A.1    She, P.2    Peroni, O.D.3    Lynch, C.J.4    Kahn, B.B.5
  • 40
    • 84900410413 scopus 로고    scopus 로고
    • Nicotinamide N-methyltransferase knockdown protects against diet-induced obesity
    • Kraus D, Yang Q, Kong D, et al. Nicotinamide N-methyltransferase knockdown protects against diet-induced obesity. Nature 2014;508:258-262
    • (2014) Nature , vol.508 , pp. 258-262
    • Kraus, D.1    Yang, Q.2    Kong, D.3
  • 41
    • 73649149038 scopus 로고    scopus 로고
    • Proteomic analysis of GLUT4 storage vesicles reveals LRP1 to be an important vesicle component and target of insulin signaling
    • Jedrychowski MP, Gartner CA, Gygi SP, et al. Proteomic analysis of GLUT4 storage vesicles reveals LRP1 to be an important vesicle component and target of insulin signaling. J Biol Chem 2010;285:104-114
    • (2010) J Biol Chem , vol.285 , pp. 104-114
    • Jedrychowski, M.P.1    Gartner, C.A.2    Gygi, S.P.3
  • 42
    • 77956358594 scopus 로고    scopus 로고
    • Ras-related protein Rab10 facilitates TLR4 signaling by promoting replenishment of TLR4 onto the plasma membrane
    • Wang D, Lou J, Ouyang C, et al. Ras-related protein Rab10 facilitates TLR4 signaling by promoting replenishment of TLR4 onto the plasma membrane. Proc Natl Acad Sci U S A 2010;107:13806-13811
    • (2010) Proc Natl Acad Sci U S A , vol.107 , pp. 13806-13811
    • Wang, D.1    Lou, J.2    Ouyang, C.3
  • 43
    • 84873813295 scopus 로고    scopus 로고
    • A Rab10-dependent mechanism for polarized basement membrane secretion during organ morphogenesis
    • Lerner DW, McCoy D, Isabella AJ, et al. A Rab10-dependent mechanism for polarized basement membrane secretion during organ morphogenesis. Dev Cell 2013;24:159-168
    • (2013) Dev Cell , vol.24 , pp. 159-168
    • Lerner, D.W.1    McCoy, D.2    Isabella, A.J.3
  • 44
    • 84879658602 scopus 로고    scopus 로고
    • Myosin Vb controls biogenesis of post-Golgi Rab10 carriers during axon development
    • Liu Y, Xu XH, Chen Q, et al. Myosin Vb controls biogenesis of post-Golgi Rab10 carriers during axon development. Nat Commun 2013;4:2005
    • (2013) Nat Commun , vol.4 , pp. 2005
    • Liu, Y.1    Xu, X.H.2    Chen, Q.3
  • 45
    • 84873358822 scopus 로고    scopus 로고
    • Rab10 GTPase regulates ER dynamics and morphology
    • English AR, Voeltz GK. Rab10 GTPase regulates ER dynamics and morphology. Nat Cell Biol 2013;15:169-178
    • (2013) Nat Cell Biol , vol.15 , pp. 169-178
    • English, A.R.1    Voeltz, G.K.2
  • 46
    • 84869195388 scopus 로고    scopus 로고
    • Deletion of Rab GAP AS160 modifies glucose uptake and GLUT4 translocation in primary skeletal muscles and adipocytes and impairs glucose homeostasis
    • Lansey MN, Walker NN, Hargett SR, Stevens JR, Keller SR. Deletion of Rab GAP AS160 modifies glucose uptake and GLUT4 translocation in primary skeletal muscles and adipocytes and impairs glucose homeostasis. Am J Physiol Endocrinol Metab 2012;303:E1273-E1286
    • (2012) Am J Physiol Endocrinol Metab , vol.303 , pp. E1273-E1286
    • Lansey, M.N.1    Walker, N.N.2    Hargett, S.R.3    Stevens, J.R.4    Keller, S.R.5
  • 47
    • 84871447109 scopus 로고    scopus 로고
    • AS160 deficiency causes wholebody insulin resistance via composite effects in multiple tissues
    • Wang HY, Ducommun S, Quan C, et al. AS160 deficiency causes wholebody insulin resistance via composite effects in multiple tissues. Biochem J 2013;449:479-489
    • (2013) Biochem J , vol.449 , pp. 479-489
    • Wang, H.Y.1    Ducommun, S.2    Quan, C.3
  • 48
    • 84928656678 scopus 로고    scopus 로고
    • PKB-Mediated Thr649 Phosphorylation of AS160/TBC1D4 Regulates the R-Wave Amplitude in the Heart
    • Quan C, Xie B, Wang HY, Chen S. PKB-Mediated Thr649 Phosphorylation of AS160/TBC1D4 Regulates the R-Wave Amplitude in the Heart. PLoS One 2015;10:e0124491
    • (2015) PLoS One , vol.10
    • Quan, C.1    Xie, B.2    Wang, H.Y.3    Chen, S.4
  • 49
    • 84946034775 scopus 로고    scopus 로고
    • Akt substrate of 160 kD regulates Na+,K+-ATPase trafficking in response to energy depletion and renal ischemia
    • Alves DS, Thulin G, Loffing J, Kashgarian M, Caplan MJ. Akt substrate of 160 kD regulates Na+,K+-ATPase trafficking in response to energy depletion and renal ischemia. J Am Soc Nephrol 2015;26:2765-2776
    • (2015) J Am Soc Nephrol , vol.26 , pp. 2765-2776
    • Alves, D.S.1    Thulin, G.2    Loffing, J.3    Kashgarian, M.4    Caplan, M.J.5
  • 50
    • 4644300287 scopus 로고    scopus 로고
    • Insulin stimulation of GLUT4 exocytosis, but not its inhibition of endocytosis, is dependent on RabGAP AS160
    • Zeigerer A, McBrayer MK, McGraw TE. Insulin stimulation of GLUT4 exocytosis, but not its inhibition of endocytosis, is dependent on RabGAP AS160. Mol Biol Cell 2004;15:4406-4415
    • (2004) Mol Biol Cell , vol.15 , pp. 4406-4415
    • Zeigerer, A.1    McBrayer, M.K.2    McGraw, T.E.3
  • 52
    • 33947592425 scopus 로고    scopus 로고
    • The glucose transporter 4-regulating protein TUG is essential for highly insulin-responsive glucose uptake in 3T3-L1 adipocytes
    • Yu C, Cresswell J, Löffler MG, Bogan JS. The glucose transporter 4-regulating protein TUG is essential for highly insulin-responsive glucose uptake in 3T3-L1 adipocytes. J Biol Chem 2007;282:7710-7722
    • (2007) J Biol Chem , vol.282 , pp. 7710-7722
    • Yu, C.1    Cresswell, J.2    Löffler, M.G.3    Bogan, J.S.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.