AS160 deficiency causes whole-body insulin resistance via composite effects in multiple tissues

Biochemical Journal

Volumn 449, Issue 2, 2013, Pages 479-489

  Wang, Hong Yu ^a   Ducommun, Serge ^b,c   Quan, Chao ^a   Xie, Bingxian ^a   Li, Min ^a   Wasserman, David H ^d   Sakamoto, Kei ^b,c   Mackintosh, Carol ^b   Chen, Shuai ^a  

^a NANJING UNIVERSITY   (China)

^b UNIVERSITY OF DUNDEE   (United Kingdom)

^c NESTLÉ RESEARCH CENTER   (Switzerland)

^d VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Akt substrate of 160 kDa (AS160); Glucose transport; Insulin resistance; Liver; Muscle

Indexed keywords

ADIPONECTIN; FATTY ACID; GLUCOSE; GLYCOGEN; GUANOSINE TRIPHOSPHATASE ACTIVATING PROTEIN; PHOSPHOENOLPYRUVATE CARBOXYKINASE (GTP); PROTEIN AS160; TRIACYLGLYCEROL; UNCLASSIFIED DRUG;

ADIPOCYTE; ADIPOSE TISSUE; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL FRACTIONATION; CONTROLLED STUDY; DIET RESTRICTION; EXTENSOR DIGITORUM LONGUS MUSCLE; GLUCOSE BLOOD LEVEL; GLUCOSE HOMEOSTASIS; GLUCOSE TOLERANCE TEST; GLUCOSE TRANSPORT; GLYCOGEN MUSCLE LEVEL; IMMUNOPRECIPITATION; INSULIN RESISTANCE; LIVER; LIVER FUNCTION; MOUSE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN DEFICIENCY; PROTEIN EXPRESSION; SOLEUS MUSCLE;

ADIPOCYTES; ADIPOSE TISSUE; ANIMALS; BLOOD GLUCOSE; BLOTTING, WESTERN; CELLS, CULTURED; FEMALE; GLUCOSE; GLUCOSE TOLERANCE TEST; GLUCOSE TRANSPORTER TYPE 4; GLYCOGEN SYNTHASE KINASE 3; GTPASE-ACTIVATING PROTEINS; HUMANS; HYPOGLYCEMIC AGENTS; INSULIN; INSULIN RESISTANCE; LIVER; MALE; MICE; MICE, KNOCKOUT; MUSCLE, SKELETAL; PHOSPHOENOLPYRUVATE CARBOXYKINASE (GTP); PHOSPHORYLATION;

MUS;

EID: 84871447109     PISSN: 02646021     EISSN: 14708728     Source Type: Journal    
DOI: 10.1042/BJ20120702     Document Type: Article

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