One-Step "click Chemistry"-Synthesized Cross-Linked Prodrug Nanogel for Highly Selective Intracellular Drug Delivery and Upregulated Antitumor Efficacy

ACS Applied Materials and Interfaces

Volumn 8, Issue 17, 2016, Pages 10673-10682

  Zhang, Yu ^a   Ding, Jianxun ^a   Li, Mingqiang ^a   Chen, Xin ^a,b   Xiao, Chunsheng ^a   Zhuang, Xiuli ^a   Huang, Yubin ^a   Chen, Xuesi ^a  

^a CHANGCHUN INSTITUTE OF APPLIED CHEMISTRY   (China)

^b UNIVERSITY OF CHINESE ACADEMY OF SCIENCES   (China)

Author keywords

cancer therapy; click chemistry; cross linking; intracellular drug delivery; prodrug; responsiveness

Indexed keywords

CROSSLINKING; DISEASES; DRUG PRODUCTS; NANOSTRUCTURED MATERIALS; ONCOLOGY; PH; POLYMERS; SYNTHESIS (CHEMICAL); TUMORS;

CANCER THERAPY; CLICK CHEMISTRY; INTRACELLULAR DRUG DELIVERY; PRODRUGS; RESPONSIVENESS;

DRUG THERAPY;

ANTINEOPLASTIC ANTIBIOTIC; DOXORUBICIN; MACROGOL DERIVATIVE; NANOGEL; POLYETHYLENEIMINE; PRODRUG;

ANIMAL; CLICK CHEMISTRY; HUMAN; PH; TISSUE DISTRIBUTION;

ANIMALS; ANTIBIOTICS, ANTINEOPLASTIC; CLICK CHEMISTRY; DOXORUBICIN; HUMANS; HYDROGEN-ION CONCENTRATION; POLYETHYLENE GLYCOLS; POLYETHYLENEIMINE; PRODRUGS; TISSUE DISTRIBUTION;

EID: 84969627594     PISSN: 19448244     EISSN: 19448252     Source Type: Journal    
DOI: 10.1021/acsami.6b00426     Document Type: Article

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