Knockout of endothelin type B receptor signaling attenuates bleomycin-induced skin sclerosis in mice

Arthritis Research and Therapy

Volumn 18, Issue 1, 2016, Pages

  Akashi, Kengo ^a   Saegusa, Jun ^a   Sendo, Sho ^a   Nishimura, Keisuke ^a   Okano, Takuya ^a,b   Yagi, Keiko ^b   Yanagisawa, Masashi ^c   Emoto, Noriaki ^a,b   Morinobu, Akio ^a  

^a KOBE UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^b KOBE PHARMACEUTICAL UNIVERSITY   (Japan)

^c UNIVERSITY OF TSUKUBA   (Japan)

Author keywords

Dermal fibroblast; Endothelin type B receptor; Systemic sclerosis

Indexed keywords

ALPHA SMOOTH MUSCLE ACTIN; BLEOMYCIN; DOPAMINE BETA MONOOXYGENASE; ENDOTHELIN RECEPTOR; ENDOTHELIN RECEPTOR TYPE B; UNCLASSIFIED DRUG; ANTINEOPLASTIC ANTIBIOTIC; COLLAGEN TYPE 1; EDNRB PROTEIN, MOUSE; ENDOTHELIN 1; ENDOTHELIN B RECEPTOR;

AGANGLIONOSIS; ALPHASMA GENE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL ACTIVATION; CELL COUNT; CELL ISOLATION; COL1ALPHA1 GENE; COLLAGEN SYNTHESIS; CONTROLLED STUDY; DERMIS; ET 1 GENE; GENE EXPRESSION; HUMAN; IN VITRO STUDY; MOUSE; MYOFIBROBLAST; NONHUMAN; PROMOTER REGION; PROTEIN FUNCTION; SCLERODERMA; SIGNAL TRANSDUCTION; SKINFOLD THICKNESS; SUBCUTANEOUS FAT; TRANSGENE; ANIMAL; C57BL MOUSE; DISEASE MODEL; FIBROBLAST; FIBROSIS; IMMUNOHISTOCHEMISTRY; KNOCKOUT MOUSE; METABOLISM; PATHOLOGY; PHYSIOLOGY; POLYMERASE CHAIN REACTION; SKIN; SYSTEMIC SCLEROSIS;

ANIMALS; ANTIBIOTICS, ANTINEOPLASTIC; BLEOMYCIN; COLLAGEN TYPE I; DISEASE MODELS, ANIMAL; ENDOTHELIN-1; FIBROBLASTS; FIBROSIS; IMMUNOHISTOCHEMISTRY; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; POLYMERASE CHAIN REACTION; RECEPTOR, ENDOTHELIN B; SCLERODERMA, SYSTEMIC; SIGNAL TRANSDUCTION; SKIN;

EID: 84969504557     PISSN: 14786354     EISSN: 14786362     Source Type: Journal    
DOI: 10.1186/s13075-016-1011-4     Document Type: Article

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