Endothelin stimulates transforming growth factor-β1 and collagen synthesis in stellate cells from control but not cirrhotic rat liver

European Journal of Pharmacology

Volumn 406, Issue 3, 2000, Pages 311-318

  Gandhi, Chandrashekhar R ^a,b   Kuddus, Ruhul H ^a   Uemura, Tadahiro ^a   Rao, Abdul S ^a  

^a UNIVERSITY OF PITTSBURGH MEDICAL CENTER   (United States)

^b UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

Author keywords

Cirrhosis; Endothelin; Fibrosis; Liver; Rat; Stellate cell

Indexed keywords

CARBON TETRACHLORIDE; COLLAGEN; COLLAGEN TYPE 1; COMPLEMENTARY DNA; CYCLO(DEXTRO TRYPTOPHYL DEXTRO ASPARTYLPROLYL DEXTRO VALYLLEUCYL); ENDOTHELIN 1; ENDOTHELIN A RECEPTOR; ENDOTHELIN A RECEPTOR ANTAGONIST; ENDOTHELIN B RECEPTOR; IODINE 125; MESSENGER RNA; N (2,6 DIMETHYLPIPERIDINOCARBONYL) 4 METHYLLEUCYL DEXTRO (1 METHOXYCARBONYLTRYPTOPHANYL) DEXTRO NORLEUCINE; PHENOBARBITAL; TRANSFORMING GROWTH FACTOR BETA1;

ANIMAL CELL; ANIMAL MODEL; ARTICLE; COLLAGEN SYNTHESIS; CONTROLLED STUDY; FIBROGENESIS; GENE EXPRESSION; LIVER CELL; LIVER CIRRHOSIS; LIVER DISEASE; LIVER FIBROSIS; NONHUMAN; PRIORITY JOURNAL; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; STELLATE CELL;

ANIMAL; COLLAGEN; ENDOTHELIN-1; LIVER; LIVER CIRRHOSIS, EXPERIMENTAL; MALE; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, ENDOTHELIN; RNA, MESSENGER; SUPPORT, U.S. GOV'T, NON-P.H.S.; SUPPORT, U.S. GOV'T, P.H.S.; TRANSFORMING GROWTH FACTOR BETA;

EID: 0034693155     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0014-2999(00)00683-X     Document Type: Article

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