Knockout of endothelial cell-derived endothelin-1 attenuates skin fibrosis but accelerates cutaneous wound healing

PLoS ONE

Volumn 9, Issue 5, 2014, Pages

  Makino, Katsunari ^a   Jinnin, Masatoshi ^a   Aoi, Jun ^a   Kajihara, Ikko ^a   Makino, Takamitsu ^a   Fukushima, Satoshi ^a   Sakai, Keisuke ^a   Nakayama, Kazuhiko ^b   Emoto, Noriaki ^b   Yanagisawa, Masashi ^c,d   Ihn, Hironobu ^a  

^a KUMAMOTO UNIVERSITY   (Japan)

^b KOBE PHARMACEUTICAL UNIVERSITY   (Japan)

^c UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^d UNIVERSITY OF TSUKUBA   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

COLLAGEN; CONNECTIVE TISSUE GROWTH FACTOR; ENDOTHELIN 1; ENDOTHELIN RECEPTOR; MESSENGER RNA; TRANSFORMING GROWTH FACTOR BETA; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; CTGF GENE; DOWN REGULATION; DRUG TARGETING; ENDOTHELIUM CELL; EPITHELIZATION; FIBROGENESIS; GENE EXPRESSION; GENE SILENCING; GRANULATION TISSUE; KNOCKOUT MOUSE; MOUSE; NONHUMAN; SKIN; SKIN FIBROSIS; SYSTEMIC SCLEROSIS; THICKNESS; TRANSFORMING GROWTH FACTOR BETA GENE; TUMOR NECROSIS FACTOR ALPHA GENE; VASCULAR ENDOTHELIUM; WOUND HEALING; ANIMAL; FIBROSIS; GENETICS; METABOLISM; PATHOPHYSIOLOGY; PHYSIOLOGY; SKIN DISEASE;

ANIMALS; ENDOTHELIN-1; FIBROSIS; MICE; MICE, KNOCKOUT; SKIN DISEASES; WOUND HEALING;

EID: 84901311288     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0097972     Document Type: Article

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