PH-Dependent Activity of Dextran-Coated Cerium Oxide Nanoparticles on Prohibiting Osteosarcoma Cell Proliferation

ACS Biomaterials Science and Engineering

Volumn 1, Issue 11, 2015, Pages 1096-1103

  Alpaslan, Ece ^a   Yazici, Hilal ^a   Golshan, Negar H ^a   Ziemer, Katherine S ^a   Webster, Thomas J ^a,b  

^a Northeastern University   (United States)

^b KING ABDULAZIZ UNIVERSITY   (Saudi Arabia)

Author keywords

and nanoparticle based therapy; bone cancer; cancer treatment; Nanoceria; osteosarcoma

Indexed keywords

CERIUM OXIDE NANOPARTICLE; DEXTRAN;

ARTICLE; BONE CELL; CANCER GROWTH; CELL PROLIFERATION; CELL VIABILITY; CONTROLLED STUDY; DRUG SYNTHESIS; IC50; OSTEOBLAST; OSTEOSARCOMA; OSTEOSARCOMA CELL; PH; PRIORITY JOURNAL;

EID: 84969248541     PISSN: None     EISSN: 23739878     Source Type: Journal    
DOI: 10.1021/acsbiomaterials.5b00194     Document Type: Article

References (48)

1. Siegel, R.; Ma, J.; Zou, Z.; Jemal, A. Cancer statistics, 2014 Ca-Cancer J. Clin. 2014, 64, 9-29 10.3322/caac.21208
2. Chertok, B.; Moffat, B. A.; David, A. E.; Yu, F. Q.; Bergemann, C.; Ross, B. D. et al. Iron oxide nanoparticles as a drug delivery vehicle for mri monitored magnetic targeting of brain tumors Biomaterials 2008, 29, 487-96 10.1016/j.biomaterials.2007.08.050
3. Dhule, S. S.; Penfornis, P.; He, J. B.; Harris, M. R.; Terry, T.; John, V. et al. The combined effect of encapsulating curcumin and c6 ceramide in liposomal nanoparticles against osteosarcoma Mol. Pharmaceutics 2014, 11, 417-27 10.1021/mp400366r
4. Barua, S.; Mitragotri, S. Challenges associated with penetration of nanoparticles across cell and tissue barriers: A review of current status and future prospects Nano Today 2014, 9, 223-43 10.1016/j.nantod.2014.04.008
5. Wilczewska, A. Z.; Niemirowicz, K.; Markiewicz, K. H.; Car, H. Nanoparticles as drug delivery systems Pharmacol. Rep. 2012, 64, 1020-37 10.1016/S1734-1140(12)70901-5
6. Wang, A. Z.; Langer, R.; Farokhzad, O. C. Nanoparticle delivery of cancer drugs Annu. Rev. Med. 2012, 63, 185-98 10.1146/annurev-med-040210-162544
7. Palakurthi, S.; Yellepeddi, V. K.; Vangara, K. K. Recent trends in cancer drug resistance reversal strategies using nanoparticles Expert Opin. Drug Delivery 2012, 9, 287-301 10.1517/17425247.2012.665365
8. Alili, L.; Sack, M.; Karakoti, A. S.; Teuber, S.; Puschmann, K.; Hirst, S. M. et al. Combined cytotoxic and anti-invasive properties of redox-active nanoparticles in tumor-stroma interactions Biomaterials 2011, 32, 2918-29 10.1016/j.biomaterials.2010.12.056
9. Park, E.-J.; Choi, J.; Park, Y.-K.; Park, K. Oxidative stress induced by cerium oxide nanoparticles in cultured beas-2b cells Toxicology 2008, 245, 90-100 10.1016/j.tox.2007.12.022
10. Bouzigues, C.; Gacoin, T.; Alexandrou, A. Biological applications of rare-earth based nanoparticles ACS Nano 2011, 5, 8488-505 10.1021/nn202378b
11. Karakoti, A. S.; Monteiro-Riviere, N. A.; Aggarwal, R.; Davis, J. P.; Narayan, R. J.; Self, W. T. et al. Nanoceria as antioxidant: Synthesis and biomedical applications JOM 2008, 60, 33-7 10.1007/s11837-008-0029-8
12. Lord, M. S.; Tsoi, B.; Gunawan, C.; Teoh, W. Y.; Amal, R.; Whitelock, J. M. Anti-angiogenic activity of heparin functionalised cerium oxide nanoparticles Biomaterials 2013, 34, 8808-18 10.1016/j.biomaterials.2013.07.083
13. Asati, A.; Santra, S.; Kaittanis, C.; Perez, J. M. Surface-charge-dependent cell localization and cytotoxicity of cerium oxide nanoparticles ACS Nano 2010, 4, 5321-31 10.1021/nn100816s
14. Sack, M.; Alili, L.; Karaman, E.; Das, S.; Gupta, A.; Seal, S. et al. Combination of conventional chemotherapeutics with redox-active cerium oxide nanoparticles-a novel aspect in cancer therapy Mol. Cancer Ther. 2014, 13, 1740-9 10.1158/1535-7163.MCT-13-0950
15. Alili, L.; Sack, M.; von Montfort, C.; Giri, S.; Das, S.; Carroll, K. S. et al. Downregulation of tumor growth and invasion by redox-active nanoparticles Antioxid. Redox Signaling 2013, 19, 765-78 10.1089/ars.2012.4831
16. Das, S.; Dowding, J. M.; Klump, K. E.; McGinnis, J. F.; Self, W.; Seal, S. Cerium oxide nanoparticles: Applications and prospects in nanomedicine Nanomedicine 2013, 8, 1483-508 10.2217/nnm.13.133
17. Asati, A.; Santra, S.; Kaittanis, C.; Nath, S.; Perez, J. M. Oxidase-like activity of polymer-coated cerium oxide nanoparticles Angew. Chem., Int. Ed. 2009, 48, 2308-12 10.1002/anie.200805279
18. Dowding, J. M.; Das, S.; Kumar, A.; Dosani, T.; McCormack, R.; Gupta, A. et al. Cellular interaction and toxicity depend on physicochemical properties and surface modification of redox-active nanomaterials ACS Nano 2013, 7, 4855-68 10.1021/nn305872d
19. Wason, M. S.; Zhao, J. Cerium oxide nanoparticles: Potential applications for cancer and other diseases Am. J. Transl. Res. 2013, 5, 126-31
20. Waris, G.; Ahsan, H. Reactive oxygen species: Role in the development of cancer and various chronic conditions J. Carcinog. 2006, 5, 14 10.1186/1477-3163-5-14
21. Campbell, C. T.; Peden, C. H. F. Chemistry-oxygen vacancies and catalysis on ceria surfaces Science 2005, 309, 713-714 10.1126/science.1113955
22. Dunnick, K. M.; Pillai, R.; Pisane, K. L.; Stefaniak, A. B.; Sabolsky, E. M.; Leonard, S. S. The effect of cerium oxide nanoparticle valence state on reactive oxygen species and toxicity Biol. Trace Elem. Res. 2015, 166, 96-107 10.1007/s12011-015-0297-4
23. Patil, S.; Sandberg, A.; Heckert, E.; Self, W.; Seal, S. Protein adsorption and cellular uptake of cerium oxide nanoparticles as a function of zeta potential Biomaterials 2007, 28, 4600-7 10.1016/j.biomaterials.2007.07.029
24. Asati, A.; Santra, S.; Kaittanis, C.; Nath, S.; Perez, J. M. Oxidase-like activity of polymer-coated cerium oxide nanoparticles Angew. Chem., Int. Ed. 2009, 48, 2308-12 10.1002/anie.200805279
25. Perez, J. M.; Asati, A.; Nath, S.; Kaittanis, C. Synthesis of biocompatible dextran-coated nanoceria with ph-dependent antioxidant properties Small 2008, 4, 552-6 10.1002/smll.200700824
26. Zhai, Y.; Zhou, K.; Xue, Y.; Qin, F.; Yang, L.; Yao, X. Synthesis of water-soluble chitosan-coated nanoceria with excellent antioxidant properties RSC Adv. 2013, 3, 6833-8 10.1039/c3ra22251a
27. Yazici, H.; Alpaslan, E.; Webster, T. J. The role of dextran coatings on the cytotoxicity properties of ceria nanoparticles toward bone cancer cells JOM 2015, 67, 804-10 10.1007/s11837-015-1336-5
28. Karakoti, A.; Kuchibhatla, S. V.; Babu, K. S.; Seal, S. Direct synthesis of nanoceria in aqueous polyhydroxyl solutions J. Phys. Chem. C 2007, 111, 17232-40 10.1021/jp076164k
29. Lin, W.; Huang, Y.-w.; Zhou, X.-D.; Ma, Y. Toxicity of cerium oxide nanoparticles in human lung cancer cells Int. J. Toxicol. 2006, 25, 451-7 10.1080/10915810600959543
30. Giri, S.; Karakoti, A.; Graham, R. P.; Maguire, J. L.; Reilly, C. M.; Seal, S. Nanoceria: A rare-earth nanoparticle as a novel anti-angiogenic therapeutic agent in ovarian cancer PLoS One 2013, 8, e54578 10.1371/journal.pone.0054578
31. Gao, Y.; Chen, K.; Ma, J.-l.; Gao, F. Cerium oxide nanoparticles in cancer OncoTargets Ther. 2014, 7, 835-40 10.2147/OTT.S62057
32. Wason, M. S.; Colon, J.; Das, S.; Seal, S.; Turkson, J.; Zhao, J. H. et al. Sensitization of pancreatic cancer cells to radiation by cerium oxide nanoparticle-induced ros production Nanomedicine 2013, 9, 558-69 10.1016/j.nano.2012.10.010
33. Hussain, S.; Al-Nsour, F.; Rice, A. B.; Marshburn, J.; Yingling, B.; Ji, Z. et al. Cerium dioxide nanoparticles induce apoptosis and autophagy in human peripheral blood monocytes ACS Nano 2012, 6, 5820-9 10.1021/nn302235u
34. Morton, S. W.; Shah, N. J.; Quadir, M. A.; Deng, Z. J.; Poon, Z.; Hammond, P. T. Osteotropic therapy via targeted layer-by-layer nanoparticles Adv. Healthcare Mater. 2014, 3, 867-75 10.1002/adhm.201300465
35. Marina, N.; Gebhardt, M.; Teot, L.; Gorlick, R. Biology and therapeutic advances for pediatric osteosarcoma Oncologist 2004, 9, 422-441 10.1634/theoncologist.9-4-422
36. Chang, R.; Sun, L. L.; Webster, T. J. Short communication: Selective cytotoxicity of curcumin on osteosarcoma cells compared to healthy osteoblasts Int. J. Nanomed. 2014, 9, 461-465 10.2147/IJN.S55505
37. Dhule, S. S.; Penfornis, P.; Frazier, T.; Walker, R.; Feldman, J.; Tan, G. et al. Curcumin-loaded gamma-cyclodextrin liposomal nanoparticles as delivery vehicles for osteosarcoma Nanomedicine 2012, 8, 440-51 10.1016/j.nano.2011.07.011
38. Yang, S.; Chen, D. Y.; Li, N. J.; Mei, X.; Qi, X. X.; Li, H. et al. A facile preparation of targetable ph-sensitive polymeric nanocarriers with encapsulated magnetic nanoparticles for controlled drug release J. Mater. Chem. 2012, 22, 25354-61 10.1039/c2jm34817a
39. Gerweck, L. E.; Seetharaman, K. Cellular ph gradient in tumor versus normal tissue: Potential exploitation for the treatment of cancer Cancer Res. 1996, 56, 1194-1198
40. Lewinski, N.; Colvin, V.; Drezek, R. Cytotoxicity of nanoparticles Small 2008, 4, 26-49 10.1002/smll.200700595
41. Verma, A.; Stellacci, F. Effect of surface properties on nanoparticle-cell interactions Small 2010, 6, 12-21 10.1002/smll.200901158
42. Nel, A. E.; Madler, L.; Velegol, D.; Xia, T.; Hoek, E. M. V.; Somasundaran, P. et al. Understanding biophysicochemical interactions at the nano-bio interface Nat. Mater. 2009, 8, 543-57 10.1038/nmat2442
43. Qi, L.; Fresnais, J.; Muller, P.; Theodoly, O.; Berret, J.-F.; Chapel, J.-P. Interfacial activity of phosphonated-peg functionalized cerium oxide nanoparticles Langmuir 2012, 28, 11448-56 10.1021/la302173g
44. Safi, M.; Courtois, J.; Seigneuret, M.; Conjeaud, H.; Berret, J.-F. The effects of aggregation and protein corona on the cellular internalization of iron oxide nanoparticles Biomaterials 2011, 32, 9353-63 10.1016/j.biomaterials.2011.08.048
45. Ould-Moussa, N.; Safi, M.; Guedeau-Boudeville, M.-A.; Montero, D.; Conjeaud, H.; Berret, J.-F. In vitro toxicity of nanoceria: Effect of coating and stability in biofluids Nanotoxicology 2014, 8, 799-811 10.3109/17435390.2013.831501
46. Lord, M. S.; Jung, M.; Teoh, W. Y.; Gunawan, C.; Vassie, J. A.; Amal, R. et al. Cellular uptake and reactive oxygen species modulation of cerium oxide nanoparticles in human monocyte cell line u937 Biomaterials 2012, 33, 7915-24 10.1016/j.biomaterials.2012.07.024
47. Das, S.; Chigurupati, S.; Dowding, J.; Munusamy, P.; Baer, D. R.; McGinnis, J. F. et al. Therapeutic potential of nanoceria in regenerative medicine MRS Bull. 2014, 39, 976-83 10.1557/mrs.2014.221
48. Cafun, J. D.; Kvashnina, K. O.; Casals, E.; Puntes, V. F.; Glatzel, P. Absence of ce3+ sites in chemically active colloidal ceria nanoparticles ACS Nano 2013, 7, 10726-32 10.1021/nn403542p