Sensitization of pancreatic cancer cells to radiation by cerium oxide nanoparticle-induced ROS production

Nanomedicine: Nanotechnology, Biology, and Medicine

Volumn 9, Issue 4, 2013, Pages 558-569

  Wason, Melissa S ^a   Colon, Jimmie ^d   Das, Soumen ^b,c   Seal, Sudipta ^b,c   Turkson, James ^a   Zhao, Jihe ^a   Baker, Cheryl H ^a,d  

^a UNIVERSITY OF CENTRAL FLORIDA COLLEGE OF MEDICINE   (United States)

^b University of Central Florida   (United States)

^c UNIVERSITY OF CENTRAL FLORIDA   (United States)

^d M D ANDERSON CANCER CENTER ORLANDO   (United States)

Author keywords

Cerium oxide nanoparticles; Pancreatic cancer; Radiation; ROS; Sensitizer

Indexed keywords

ACIDIC ENVIRONMENT; CANCER CELL APOPTOSIS; CERIUM OXIDE NANOPARTICLE; PANCREATIC CANCERS; REACTIVE OXYGEN SPECIES; ROS; SENSITIZER; SUPEROXIDE RADICAL;

CELL DEATH; DISEASES; HEAT RADIATION; NANOPARTICLES; OXIDES; OXYGEN; TUMORS;

RADIOTHERAPY;

CERIUM OXIDE; CERIUM OXIDE NANOPARTICLE; NANOPARTICLE; PEROXIDE; REACTIVE OXYGEN METABOLITE; SUPEROXIDE; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; CONTROLLED STUDY; GROWTH; HUMAN; HUMAN CELL; MOUSE; NONHUMAN; PANCREAS CANCER; PANCREAS TUMOR; PH; SENSITIZATION; TRANSMISSION ELECTRON MICROSCOPY;

CELL LINE, TUMOR; CERIUM; HUMANS; HYDROGEN PEROXIDE; METAL NANOPARTICLES; PANCREATIC NEOPLASMS; RADIATION-SENSITIZING AGENTS; REACTIVE OXYGEN SPECIES;

MUS;

EID: 84876707046     PISSN: 15499634     EISSN: 15499642     Source Type: Journal    
DOI: 10.1016/j.nano.2012.10.010     Document Type: Article

References (32)

1. Sharma C., Eltawil K.M., Renfrew P.D., Walsh M.J., Molinari M. Advances in diagnosis, treatment and palliation of pancreatic carcinoma: 1990-2010. World J Gastroenterol 2011, 17:867-897.
2. Kouvaris J.R., Kouloulias V.E., Vlahos L.J. Amifostine: the first selective-target and broad-spectrum radioprotector. Oncologist 2007, 12:738-747.
3. Stolarska M., Mlynarski W., Zalewska-Szewczyk B., Bodalski J. Cytoprotective effect of amifostine in the treatment of childhood neoplastic diseases-a clinical study including the pharmacoeconomic analysis. Pharmacol Rep 2006, 58:30-34.
4. Krug L.M., Curley T., Schwartz L., Richardson S., Marks P., Chiao J., Kelly W.K. Potential role of histone deacetylase inhibitors in mesothelioma: clinical experience with suberoylanilide hydroxamic acid. Clin Lung Cancer 2006, 7:257-261.
5. Huang P., Yang D.P., Zhang C., Lin J., He M., Bao L., Cui D. Protein-directed one-pot synthesis of Ag microspheres with good biocompatibility and enhancement of radiation effects on gastric cancer cells. Nanoscale 2011, 3:3623-3626.
6. Huang P., Bao L., Zhang C., Lin J., Luo T., Yang D., He M., Li Z., Gao G., Gao B., Fu S., Cui D. Folic acid-conjugated silica-modified gold nanorods for X-ray/CT imaging-guided dual-mode radiation and photo-thermal therapy. Biomaterials 2011, 32:9796-9809.
7. Gupta S., Brouwer P., Bandyopadhyay S., Patil S., Briggs R., Jain J., Seal S. TEM/AFM investigation of size and surface properties of nanocrystalline ceria. J Nanosci Nanotechnol 2005, 5:1101-1107.
8. Patil S., Sandberg A., Heckert E., Self W., Seal S. Protein adsorption and cellular uptake of cerium oxide nanoparticles as a function of zeta potential. Biomaterials 2007, 28:4600-4607.
9. Das M., Patil S., Bhargava N., Kang J.F., Riedel L.M., Seal S., Hickman J.J. Auto-catalytic ceria nanoparticles offer neuroprotection to adult rat spinal cord neurons. Biomaterials 2007, 28:1918-1925.
10. Brunner T.J., Wick P., Manser P., Spohn P., Grass R.N., Limbach L.K., Bruinink A., Stark W.J. In vitro cytotoxicity of oxide nanoparticles: comparison to asbestos, silica, and the effect of particle solubility. Environ Sci Technol 2006, 40:4374-4381.
11. Chen J., Patil S., Seal S., McGinnis J.F. Rare earth nanoparticles prevent retinal degeneration induced by intracellular peroxides. Nat Nanotechnol 2006, 1:142-150.
12. Heckert E.G., Karakoti A.S., Seal S., Self W.T. The role of cerium redox state in the SOD mimetic activity of nanoceria. Biomaterials 2008, 29:2705-2709.
13. Pirmohamed T., Dowding J.M., Singh S., Wasserman B., Heckert E., Karakoti A.S., King J.E., Seal S., Self W.T. Nanoceria exhibit redox state-dependent catalase mimetic activity. Chem Commun (Camb) 2010, 46:2736-2738.
14. Colon J., Herrera L., Smith J., Patil S., Komanski C., Kupelian P., Seal S., Jenkins D.W., Baker C.H. Protection from radiation-induced pneumonitis using cerium oxide nanoparticles. Nanomedicine 2009, 5:225-231.
15. Tarnuzzer R.W., Colon J., Patil S., Seal S. Vacancy engineered ceria nanostructures for protection from radiation-induced cellular damage. Nano Lett 2005, 5:2573-2577.
16. Colon J., Hsieh N., Ferguson A., Kupelian P., Seal S., Jenkins D.W., Baker C.H. Cerium oxide nanoparticles protect gastrointestinal epithelium from radiation-induced damage by reduction of reactive oxygen species and upregulation of superoxide dismutase 2. Nanomedicine 2010, 6:698-705.
17. Xue Y., Luan Q.F., Yang D., Yao X., Zhou K.B. Direct evidence for hydroxyl radical scavenging activity of cerium oxide nanoparticles. J Phys Chem C 2011, 115:4433-4438.
18. Asati A., Santra S., Kaittanis C., Nath S., Perez J.M. Oxidase-like activity of polymer-coated cerium oxide nanoparticles. Angew Chem Int Ed Engl 2009, 48:2308-2312.
19. Alili L., Sack M., Karakoti A.S., Teuber S., Puschmann K., Hirst S.M., Reilly C.M., Zanger K., Stahl W., Das S., Seal S., Brenneisen P. Combined cytotoxic and anti-invasive properties of redox-active nanoparticles in tumor-stroma interactions. Biomaterials 2011, 32:2918-2929.
20. Lin W., Huang Y.W., Zhou X.D., Ma Y. Toxicity of cerium oxide nanoparticles in human lung cancer cells. Int J Toxicol 2006, 25:451-457.
21. Park E.J., Choi J., Park Y.K., Park K. Oxidative stress induced by cerium oxide nanoparticles in cultured BEAS-2B cells. Toxicology 2008, 245:90-100.
22. Vincent A., Babu S., Heckert E., Dowding J., Hirst S.M., Inerbaev T.M., Self W.T., Reilly C.M., Masunov A.E., Rahman T.S., Seal S. Protonated nanoparticle surface governing ligand tethering and cellular targeting. ACS Nano 2009, 3:1203-1211.
23. Bruns C.J., Harbison M.T., Kuniyasu H., Eue I., Fidler I.J. In vivo selection and characterization of metastatic variants from human pancreatic adenocarcinoma by using orthotopic implantation in nude mice. Neoplasia 1999, 1:50-62.
24. Karakoti A.S., Kuchibhatla S.V.N.T., Suresh Babu K., Seal S. Direct synthesis of nanoceria in aqueous polyhydroxyl solutions. J Phys Chem C 2007, 111:17232-17240.
25. Deshpande S., Patil S., Kuchibhatla S.T., Seal S. Size dependency variation in lattice parameter and valency states in nanocrystalline cerium oxide. Appl Phys Lett 2005, 87.
26. Oleshko V.P., Howe J.M., Shukla S., Seal S. High-resolution and analytical TEM investigation of metastable-tetragonal phase stabilization in undoped nanocrystalline zirconia. J Nanosci Nanotechnol 2004, 4:867-875.
27. Franken N.A., Rodermond H.M., Stap J., Haveman J., van Bree C. Clonogenic assay of cells in vitro. Nat Protoc 2006, 1:2315-2319.
28. Singh V., Singh S., Das S., Kumar A., Self W.T., Seal S. A facile synthesis of PLGA encapsulated cerium oxide nanoparticles: release kinetics and biological activity. Nanoscale 2012.
29. Baker C.H., Kedar D., McCarty M.F., Tsan R., Weber K.L., Bucana C.D., Fidler I.J. Blockade of epidermal growth factor receptor signaling on tumor cells and tumor-associated endothelial cells for therapy of human carcinomas. Am J Pathol 2002, 161:929-938.
30. Baker C.H., Solorzano C.C., Fidler I.J. Blockade of vascular endothelial growth factor receptor and epidermal growth factor receptor signaling for therapy of metastatic human pancreatic cancer. Cancer Res 2002, 62:1996-2003.
31. Konduri S., Colon J., Baker C.H., Safe S., Abbruzzese J.L., Abudayyeh A., Basha M.R., Abdelrahim M. Tolfenamic acid enhances pancreatic cancer cell and tumor response to radiation therapy by inhibiting survivin protein expression. Mol Cancer Ther 2009, 8:533-542.
32. Singh S., Kumar A., Karakoti A., Seal S., Self W.T. Unveiling the mechanism of uptake and sub-cellular distribution of cerium oxide nanoparticles. Mol Biosyst 2010, 6:1813-1820.