Ectodomain cleavage of FLT1 regulates receptor activation and function and is not required for its downstream intracellular cleavage

Experimental Cell Research

Volumn 344, Issue 1, 2016, Pages 103-111

  Raikwar, Nandita S ^a   Liu, Kang Z ^a   Thomas, Christie P ^a,b  

^a UNIVERSITY OF IOWA   (United States)

^b VETERANS AFFAIRS MEDICAL CENTER   (United States)

Author keywords

MAP kinase; Proteolytic cleavage; Soluble receptor

Indexed keywords

GAMMA SECRETASE; GAMMA SECRETASE INHIBITOR; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; PRESENILIN 1; VALINE; VASCULOTROPIN; VASCULOTROPIN RECEPTOR 1; MUTANT PROTEIN; SECRETASE;

ANIMAL CELL; ARTICLE; CARBOXY TERMINAL SEQUENCE; CONDITIONED MEDIUM; CONTROLLED STUDY; COS 7 CELL LINE; DIMERIZATION; EMBRYO; ENZYME ACTIVATION; ENZYME ACTIVE SITE; HEK293 CELL LINE; HUMAN; HUMAN CELL; NONHUMAN; PEPTIDE MAPPING; PRIORITY JOURNAL; PROTEIN CLEAVAGE; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN PROCESSING; AMINO ACID SEQUENCE; ANIMAL; ANTAGONISTS AND INHIBITORS; CHEMISTRY; CHLOROCEBUS AETHIOPS; COS CELL LINE; INTRACELLULAR SPACE; METABOLISM; PROTEIN MULTIMERIZATION;

AMINO ACID SEQUENCE; AMYLOID PRECURSOR PROTEIN SECRETASES; ANIMALS; CERCOPITHECUS AETHIOPS; COS CELLS; ENZYME ACTIVATION; HEK293 CELLS; HUMANS; INTRACELLULAR SPACE; MUTANT PROTEINS; PRESENILIN-1; PROTEIN DOMAINS; PROTEIN MULTIMERIZATION; VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR-1;

EID: 84968820936     PISSN: 00144827     EISSN: 10902422     Source Type: Journal    
DOI: 10.1016/j.yexcr.2016.03.020     Document Type: Article

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