Glucocorticoid impairs cell-cell communication by autophagymediated degradation of connexin 43 in osteocytes

Oncotarget

Volumn 7, Issue 19, 2016, Pages 26966-26978

  Gao, Junjie ^a   Cheng, Tak Sum ^a   Qin, An ^b   Pavlos, Nathan J ^a   Wang, Tao ^a,c   Song, Kai ^a   Wang, Yan ^d   Chen, Lianzhi ^a   Zhou, Lin ^d   Jiang, Qing ^e   Takayanagi, Hiroshi ^a,f   Yan, Sheng ^c,d   Zheng, Minghao ^a,c,d  

^a UNIVERSITY OF WESTERN AUSTRALIA   (Australia)

^b SHANGHAI JIAO TONG UNIVERSITY SCHOOL OF MEDICINE   (China)

^c GUANGDONG PROVINCIAL PEOPLE'S HOSPITAL   (China)

^d ZHEJIANG UNIVERSITY   (China)

^e MEDICAL SCHOOL OF NANJING UNIVERSITY   (China)

^f UNIVERSITY OF TOKYO   (Japan)

Author keywords

Autophagy; Connexin 43; Gerotarget; Glucocorticoid; mTORC1; Osteocyte

Indexed keywords

AUTOPHAGY PROTEIN 5; CHLOROQUINE; CONNEXIN 43; DEXAMETHASONE; MAMMALIAN TARGET OF RAPAMYCIN COMPLEX 1; PROTEIN KINASE B; SMALL INTERFERING RNA; SOMATOMEDIN C; GJA1 PROTEIN, MOUSE; GLUCOCORTICOID;

ANIMAL CELL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; AUTOLYSOSOME; AUTOPHAGOSOME; AUTOPHAGY; CALVARIA; CELL COMMUNICATION; CONTROLLED STUDY; CYTOSKELETON; CYTOTOXICITY; DRUG EFFECT; ENZYME PHOSPHORYLATION; EX VIVO STUDY; GENE SILENCING; IN VITRO STUDY; IN VIVO STUDY; INTERNALIZATION; MALE; MOUSE; NONHUMAN; OSTEOCYTE; OSTEOLYSIS; PROTEIN DEGRADATION; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; ANIMAL; CELL CULTURE; CELL LINE; CONFOCAL MICROSCOPY; CYTOLOGY; DRUG EFFECTS; LYSOSOME; METABOLISM; TRANSGENIC MOUSE; WESTERN BLOTTING;

ANIMALS; AUTOPHAGOSOMES; AUTOPHAGY; BLOTTING, WESTERN; CELL COMMUNICATION; CELL LINE; CELLS, CULTURED; CONNEXIN 43; DEXAMETHASONE; GLUCOCORTICOIDS; LYSOSOMES; MICE, TRANSGENIC; MICROSCOPY, CONFOCAL; OSTEOCYTES; PROTEOLYSIS; SIGNAL TRANSDUCTION;

EID: 84968735303     PISSN: None     EISSN: 19492553     Source Type: Journal    
DOI: 10.18632/oncotarget.9034     Document Type: Article

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