P22phox C242T single-nucleotide polymorphism inhibits inflammatory oxidative damage to endothelial cells and vessels

Circulation

Volumn 133, Issue 24, 2016, Pages 2391-2403

  Meijles, Daniel N ^a,b   Fan, Lampson M ^c   Ghazaly, Maziah M ^b   Howlin, Brendan ^b   Krönke, Martin ^d   Brooks, Gavin ^a   Li, Jian Mei ^a  

^a UNIVERSITY OF READING   (United Kingdom)

^b UNIVERSITY OF SURREY   (United Kingdom)

^c ROYAL BERKSHIRE HOSPITAL   (United Kingdom)

^d UNIVERSITY OF COLOGNE   (Germany)

Author keywords

blood vessels; endothelium; genetics; inflammation; NADPH oxidase; structure

Indexed keywords

GLUCOSE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE; PROTEIN P22; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE 2; SHORT HAIRPIN RNA; TUMOR NECROSIS FACTOR ALPHA; CYBA PROTEIN, HUMAN; CYBB PROTEIN, HUMAN; MEMBRANE PROTEIN; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE;

ALLELE; ARTICLE; CAPILLARY ENDOTHELIAL CELL; CONTROLLED STUDY; ENDOTHELIUM CELL; FEMALE; GENETIC TRANSFECTION; HELA CELL LINE; HUMAN; HUMAN CELL; INFLAMMATION; ISCHEMIC HEART DISEASE; MOLECULAR MODEL; PHLEBOTOMY; PRIORITY JOURNAL; PROTEIN EXPRESSION; SAPHENOUS VEIN; SINGLE NUCLEOTIDE POLYMORPHISM; ANIMAL; ENZYMOLOGY; GENETICS; METABOLISM; MOUSE; OXIDATIVE STRESS; PATHOLOGY; PHYSIOLOGY; VASCULAR DISEASE;

ANIMALS; ENDOTHELIAL CELLS; HELA CELLS; HUMANS; INFLAMMATION; MEMBRANE GLYCOPROTEINS; MICE; MODELS, MOLECULAR; NADPH OXIDASE; OXIDATIVE STRESS; POLYMORPHISM, SINGLE NUCLEOTIDE; REACTIVE OXYGEN SPECIES; VASCULAR DISEASES;

EID: 84967166512     PISSN: 00097322     EISSN: 15244539     Source Type: Journal    
DOI: 10.1161/CIRCULATIONAHA.116.021993     Document Type: Article

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