LRH-1 drives colon cancer cell growth by repressing the expression of the CDKN1A gene in a p53-dependent manner

Nucleic Acids Research

Volumn 44, Issue 2, 2016, Pages 582-594

  Kramer, Holly B ^a   Lai, Chun Fui ^a   Patel, Hetal ^a   Periyasamy, Manikandan ^a   Lin, Meng Lay ^a   Feller, Stephan M ^b   Fuller Pace, Frances V ^c   Meek, David W ^c   Ali, Simak ^a   Buluwela, Laki ^a  

^a HAMMERSMITH HOSPITAL   (United Kingdom)

^b MARTIN LUTHER UNIVERSITY HALLE WITTENBERG   (Germany)

^c UNIVERSITY OF DUNDEE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIN DEPENDENT KINASE INHIBITOR 1A; LIVER RECEPTOR HOMOLOG 1; PROTEIN P21; PROTEIN P53; SMALL INTERFERING RNA; CDKN1A PROTEIN, HUMAN; CELL RECEPTOR; NR5A2 PROTEIN, HUMAN; PROTEIN BINDING;

ARTICLE; CANCER GROWTH; CDKN1A GENE; COLORECTAL CANCER; CONTROLLED STUDY; GENE EXPRESSION; GENE EXPRESSION PROFILING; GENE SILENCING; GENETIC REGULATION; HCT116 CELL LINE; HT 29 CELL LINE; HUMAN; HUMAN CELL; MICROARRAY ANALYSIS; MUTATION; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN PHOSPHORYLATION; ANTAGONISTS AND INHIBITORS; ANTIBODY SPECIFICITY; BINDING SITE; CELL PROLIFERATION; CHROMATIN ASSEMBLY AND DISASSEMBLY; GENE DELETION; GENE EXPRESSION REGULATION; GENETICS; HCT 116 CELL LINE; HT-29 CELL LINE; METABOLISM; PHOSPHORYLATION; SIGNAL TRANSDUCTION;

BINDING SITES; CELL PROLIFERATION; CHROMATIN ASSEMBLY AND DISASSEMBLY; CYCLIN-DEPENDENT KINASE INHIBITOR P21; GENE DELETION; GENE EXPRESSION REGULATION, NEOPLASTIC; HCT116 CELLS; HT29 CELLS; HUMANS; MUTATION; ORGAN SPECIFICITY; PHOSPHORYLATION; PROMOTER REGIONS, GENETIC; PROTEIN BINDING; RECEPTORS, CYTOPLASMIC AND NUCLEAR; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION; TUMOR SUPPRESSOR PROTEIN P53;

EID: 84966415487     PISSN: 03051048     EISSN: 13624962     Source Type: Journal    
DOI: 10.1093/nar/gkv948     Document Type: Article

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