Silencing LRH-1 in colon cancer cell lines impairs proliferation and alters gene expression programs

Proceedings of the National Academy of Sciences of the United States of America

Volumn 112, Issue 8, 2015, Pages 2467-2472

  Bayrer, James R ^a   Mukkamala, Sridevi ^a   Sablin, Elena P ^a   Webb, Paul ^b   Fletterick, Robert J ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b HOUSTON METHODIST RESEARCH INSTITUTE   (United States)

Author keywords

Colorectal cancer; Liver receptor homolog 1; LRH 1; NR5A2; Nuclear receptor

Indexed keywords

BILE ACID; LIVER RECEPTOR HOMOLOG 1; MESSENGER RNA; SHORT HAIRPIN RNA; CELL RECEPTOR; NR5A2 PROTEIN, HUMAN; NUCLEAR RECEPTOR SUBFAMILY 0, GROUP B, MEMBER 2;

ARTICLE; CACO 2 CELL LINE; CELL CYCLE REGULATION; CELL PROLIFERATION; CHOLESTEROL METABOLISM; COLORECTAL CANCER CELL LINE; CONTROLLED STUDY; GENE CLUSTER; GENE EXPRESSION; GENE SILENCING; HT 29 CELL LINE; HUMAN; HUMAN CELL; MICROARRAY ANALYSIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; CELL CYCLE; COLON TUMOR; DNA MICROARRAY; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; PATHOLOGY; REPRODUCIBILITY;

MURINAE;

CACO-2 CELLS; CELL CYCLE; CELL PROLIFERATION; COLONIC NEOPLASMS; GENE EXPRESSION REGULATION, NEOPLASTIC; GENE KNOCKDOWN TECHNIQUES; GENE SILENCING; HT29 CELLS; HUMANS; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; RECEPTORS, CYTOPLASMIC AND NUCLEAR; REPRODUCIBILITY OF RESULTS;

EID: 84923676029     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1500978112     Document Type: Article

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