Lung tumor exosomes induce a pro-inflammatory phenotype in mesenchymal stem cells via NFκB-TLR signaling pathway

Journal of Hematology and Oncology

Volumn 9, Issue 1, 2016, Pages

  Li, Xiaoxia ^a   Wang, Shihua ^a   Zhu, Rongjia ^a   Li, Hongling ^a   Han, Qin ^a   Zhao, Robert Chunhua ^a,b  

^a PEKING UNION MEDICAL COLLEGE   (China)

^b PEKING UNION MEDICAL COLLEGE HOSPITAL   (China)

Author keywords

Exosomes; HSP70; Inflammation; MSCs; NF B; TLR2; Tumor supportive

Indexed keywords

HEAT SHOCK PROTEIN 70; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 6; INTERLEUKIN 8; MONOCYTE CHEMOTACTIC PROTEIN 1; NEUTRALIZING ANTIBODY; SMALL INTERFERING RNA; TOLL LIKE RECEPTOR; TOLL LIKE RECEPTOR 2; AUTACOID; CCL2 PROTEIN, HUMAN;

A549 CELL LINE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOKINE RELEASE; EXOME; HUMAN; HUMAN CELL; INFLAMMATION; LUNG TUMOR; MESENCHYMAL STEM CELL; MOUSE; NONHUMAN; SIGNAL TRANSDUCTION; TUMOR GROWTH; TUMOR XENOGRAFT; ANIMAL; CELL CULTURE; DRUG EFFECTS; EXOSOME; FLUORESCENT ANTIBODY TECHNIQUE; GENETICS; IMMUNOLOGY; MESENCHYMAL STROMA CELL; METABOLISM; NUDE MOUSE; PATHOLOGY; PHENOTYPE; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA INTERFERENCE; TRANSMISSION ELECTRON MICROSCOPY; TUMOR CELL LINE; ULTRASTRUCTURE; WESTERN BLOTTING; XENOGRAFT;

ANIMALS; ANTIBODIES, NEUTRALIZING; BLOTTING, WESTERN; CELL LINE, TUMOR; CELLS, CULTURED; CHEMOKINE CCL2; EXOSOMES; FLUORESCENT ANTIBODY TECHNIQUE; HUMANS; INFLAMMATION MEDIATORS; INTERLEUKIN-6; INTERLEUKIN-8; LUNG NEOPLASMS; MESENCHYMAL STROMAL CELLS; MICE, NUDE; MICROSCOPY, ELECTRON, TRANSMISSION; NF-KAPPA B; PHENOTYPE; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA INTERFERENCE; SIGNAL TRANSDUCTION; TOLL-LIKE RECEPTOR 2; TRANSPLANTATION, HETEROLOGOUS;

EID: 84966351812     PISSN: None     EISSN: 17568722     Source Type: Journal    
DOI: 10.1186/s13045-016-0269-y     Document Type: Article

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