Obesity promotes breast cancer by CCL2-mediated macrophage recruitment and angiogenesis

Cancer Research

Volumn 73, Issue 19, 2013, Pages 6080-6093

  Arendt, Lisa M ^a,b   McCready, Jessica ^a,b,d   Keller, Patricia J ^a,b   Baker, Dana D ^b   Naber, Stephen P ^b   Seewaldt, Victoria ^c   Kuperwasser, Charlotte ^a,b  

^a TUFTS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b TUFTS MEDICAL CENTER   (United States)

^c DUKE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d ASSUMPTION COLLEGE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CD31 ANTIGEN; GLYCOPROTEIN P 15095; INDUCIBLE NITRIC OXIDE SYNTHASE; INTERLEUKIN 1BETA; MONOCYTE CHEMOTACTIC PROTEIN 1; STROMAL CELL DERIVED FACTOR 1;

ADIPOCYTE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BREAST CANCER; BREAST CARCINOGENESIS; CANCER GRADING; CANCER GROWTH; CONTROLLED STUDY; DISEASE ASSOCIATION; FEMALE; HUMAN; HUMAN CELL; IN VIVO STUDY; INTRACELLULAR SIGNALING; MACROPHAGE ACTIVATION; MACROPHAGE FUNCTION; MACROPHAGE RECRUITMENT; MALIGNANT TRANSFORMATION; MOUSE; NONHUMAN; OBESITY; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; SUBCUTANEOUS FAT; TUMOR VASCULARIZATION;

ADIPOCYTES; ANIMALS; APOPTOSIS; BLOTTING, WESTERN; BREAST; BREAST NEOPLASMS; CATTLE; CELL DIFFERENTIATION; CELL MOVEMENT; CELL PROLIFERATION; CELLS, CULTURED; CHEMOKINE CCL2; CHEMOKINE CXCL12; ENDOTHELIUM, VASCULAR; FEMALE; FLUORESCENT ANTIBODY TECHNIQUE; HUMANS; IMMUNOENZYME TECHNIQUES; IMMUNOPRECIPITATION; INTERLEUKIN-1BETA; MACROPHAGES; MAMMARY GLANDS, ANIMAL; MICE; MICE, INBRED C57BL; MICE, INBRED NOD; MICE, SCID; NEOVASCULARIZATION, PATHOLOGIC; OBESITY; RETINA; TUMOR MICROENVIRONMENT;

EID: 84885045471     PISSN: 00085472     EISSN: 15387445     Source Type: Journal    
DOI: 10.1158/0008-5472.CAN-13-0926     Document Type: Article

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