-
1
-
-
78049485263
-
Estimates of worldwide burden of cancer in 2008: GLOBOCAN 2008
-
Ferlay J,Shin HR,Bray F,Forman D,Mathers C,Parkin DM.Estimates of worldwide burden of cancer in 2008: GLOBOCAN 2008.Int J Cancer. 2010;127:2893-917.
-
(2010)
Int J Cancer
, vol.127
, pp. 2893-2917
-
-
Ferlay, J.1
Shin, H.R.2
Bray, F.3
Forman, D.4
Mathers, C.5
Parkin, D.M.6
-
2
-
-
2942590262
-
Taxane-platinum combinations in advanced non-small cell lung cancer: a review
-
Rigas JR.Taxane-platinum combinations in advanced non-small cell lung cancer: a review.Oncologist. 2004;9:16-23.
-
(2004)
Oncologist
, vol.9
, pp. 16-23
-
-
Rigas, J.R.1
-
3
-
-
60349084045
-
Epidemiology of lung cancer prognosis: quantity and quality of life
-
Yang P.Epidemiology of lung cancer prognosis: quantity and quality of life.Methods Mol Biol. 2009;471:469-86.
-
(2009)
Methods Mol Biol
, vol.471
, pp. 469-486
-
-
Yang, P.1
-
4
-
-
17944366977
-
Heat-shock protein 70 antagonizes apoptosis-inducing factor
-
Ravagnan L,Gurbuxani S,Susin SA,Maisse C,Daugas E,Zamzami N,Mak T,Jäättelä M,Penninger JM,Garrido C,Kroemer G.Heat-shock protein 70 antagonizes apoptosis-inducing factor.Nat Cell Biol. 2001;3:839-43.
-
(2001)
Nat Cell Biol
, vol.3
, pp. 839-843
-
-
Ravagnan, L.1
Gurbuxani, S.2
Susin, S.A.3
Maisse, C.4
Daugas, E.5
Zamzami, N.6
Mak, T.7
Jäättelä, M.8
Penninger, J.M.9
Garrido, C.10
Kroemer, G.11
-
5
-
-
0028961801
-
Over-expression of hsp70 confers tumorigenicity to mouse fibrosarcoma cells
-
Jaattela M.Over-expression of hsp70 confers tumorigenicity to mouse fibrosarcoma cells.Int J Cancer. 1995;60:689-93.
-
(1995)
Int J Cancer
, vol.60
, pp. 689-693
-
-
Jaattela, M.1
-
6
-
-
0030823752
-
Heat shock proteins and cell proliferation in human breast cancer biopsy samples
-
Vargas-Roig LM,Fanelli MA,Lopez LA,Gago FE,Tello O,Aznar JC,Ciocca DR.Heat shock proteins and cell proliferation in human breast cancer biopsy samples.Cancer Detect Prev. 1997;21:441-51.
-
(1997)
Cancer Detect Prev
, vol.21
, pp. 441-451
-
-
Vargas-Roig, L.M.1
Fanelli, M.A.2
Lopez, L.A.3
Gago, F.E.4
Tello, O.5
Aznar, J.C.6
Ciocca, D.R.7
-
7
-
-
0030596112
-
Expression of resistance-related proteins in tumoral and peritumoral tissues of patients with lung cancer
-
Koomagi R,Stammler G,Manegold C,Mattern J,Volm M.Expression of resistance-related proteins in tumoral and peritumoral tissues of patients with lung cancer.Cancer Lett. 1996;110:129-36.
-
(1996)
Cancer Lett
, vol.110
, pp. 129-136
-
-
Koomagi, R.1
Stammler, G.2
Manegold, C.3
Mattern, J.4
Volm, M.5
-
8
-
-
84860377679
-
Discrimination of clinical stages in non-small cell lung cancer patients by serum HSP27 and HSP70: a multi-institutional case-control study
-
Zimmermann M,Nickl S,Lambers C,Hacker S,Mitterbauer A,Hoetzenecker K,Rozsas A,Ostoros G,Laszlo V,Hofbauer H,Renyi-Vamos F,Klepetko W,Dome B,Ankersmit HJ.Discrimination of clinical stages in non-small cell lung cancer patients by serum HSP27 and HSP70: a multi-institutional case-control study.Clin Chim Acta. 2012;413:1115-20.
-
(2012)
Clin Chim Acta
, vol.413
, pp. 1115-1120
-
-
Zimmermann, M.1
Nickl, S.2
Lambers, C.3
Hacker, S.4
Mitterbauer, A.5
Hoetzenecker, K.6
Rozsas, A.7
Ostoros, G.8
Laszlo, V.9
Hofbauer, H.10
Renyi-Vamos, F.11
Klepetko, W.12
Dome, B.13
Ankersmit, H.J.14
-
9
-
-
0034608892
-
Selective depletion of heat shock protein 70 (Hsp70) activates a tumor-specific death program that is independent of caspases and bypasses Bcl-2
-
Nylandsted J,Rohde M,Brand K,Bastholm L,Elling F,Jaattela M.Selective depletion of heat shock protein 70 (Hsp70) activates a tumor-specific death program that is independent of caspases and bypasses Bcl-2.Proc Natl Acad Sci U S A. 2000;97:7871-6.
-
(2000)
Proc Natl Acad Sci U S A
, vol.97
, pp. 7871-7876
-
-
Nylandsted, J.1
Rohde, M.2
Brand, K.3
Bastholm, L.4
Elling, F.5
Jaattela, M.6
-
10
-
-
0141519224
-
Cell death induced by down-regulation of heat shock protein 70 in lung cancer cell lines is p53-independent and does not require DNA cleavage
-
Frese S,Schaper M,Kuster JR,Miescher D,Jaattela M,Buehler T,Schmid RA.Cell death induced by down-regulation of heat shock protein 70 in lung cancer cell lines is p53-independent and does not require DNA cleavage.Journal Thorac Cardiovasc Surg. 2003;126:748-54.
-
(2003)
Journal Thorac Cardiovasc Surg
, vol.126
, pp. 748-754
-
-
Frese, S.1
Schaper, M.2
Kuster, J.R.3
Miescher, D.4
Jaattela, M.5
Buehler, T.6
Schmid, R.A.7
-
11
-
-
0031443856
-
Induction of PBP74/mortalin/Grp75, a member of the hsp70 family, by low doses of ionizing radiation: a possible role in induced radioresistance
-
Sadekova S,Lehnert S,Chow TY.Induction of PBP74/mortalin/Grp75, a member of the hsp70 family, by low doses of ionizing radiation: a possible role in induced radioresistance.International J Radiat Biol. 1997;72:653-60.
-
(1997)
International J Radiat Biol
, vol.72
, pp. 653-660
-
-
Sadekova, S.1
Lehnert, S.2
Chow, T.Y.3
-
12
-
-
0034053245
-
Inducible heat-shock protein 70 is involved in the radioadaptive response
-
Park SH,Lee SJ,Chung HY,Kim TH,Cho CK,Yoo SY,Lee YS.Inducible heat-shock protein 70 is involved in the radioadaptive response.Radiat Res. 2000;153:318-26.
-
(2000)
Radiat Res
, vol.153
, pp. 318-326
-
-
Park, S.H.1
Lee, S.J.2
Chung, H.Y.3
Kim, T.H.4
Cho, C.K.5
Yoo, S.Y.6
Lee, Y.S.7
-
13
-
-
15944427810
-
Clonogenicity of human leukemic cells protected from cell-lethal agents by heat shock protein 70
-
Bases R.Clonogenicity of human leukemic cells protected from cell-lethal agents by heat shock protein 70.Cell Stress Chaperones. 2005;10:37-45.
-
(2005)
Cell Stress Chaperones
, vol.10
, pp. 37-45
-
-
Bases, R.1
-
14
-
-
0242330183
-
Overexpression of HSP70 is induced by ionizing radiation in C3H 10T1/2 cells and protects from DNA damage
-
Calini V,Urani C,Camatini M.Overexpression of HSP70 is induced by ionizing radiation in C3H 10T1/2 cells and protects from DNA damage.Toxicol In Vitro. 2003;17:561-6.
-
(2003)
Toxicol In Vitro
, vol.17
, pp. 561-566
-
-
Calini, V.1
Urani, C.2
Camatini, M.3
-
15
-
-
33748426037
-
Heat shock protein 70 enhanced deoxyribonucleic acid base excision repair in human leukemic cells after ionizing radiation
-
Bases R.Heat shock protein 70 enhanced deoxyribonucleic acid base excision repair in human leukemic cells after ionizing radiation.Cell Stress Chaperones. 2006;11:240-9.
-
(2006)
Cell Stress Chaperones
, vol.11
, pp. 240-249
-
-
Bases, R.1
-
16
-
-
0347356337
-
Genomic instability and enhanced radiosensitivity in Hsp70.1- and Hsp70.3-deficient mice
-
Hunt CR,Dix DJ,Sharma GG,Pandita RK,Gupta A,Funk M,Pandita TK.Genomic instability and enhanced radiosensitivity in Hsp70.1- and Hsp70.3-deficient mice.Mol Cell Biol. 2004;24:899-911.
-
(2004)
Mol Cell Biol
, vol.24
, pp. 899-911
-
-
Hunt, C.R.1
Dix, D.J.2
Sharma, G.G.3
Pandita, R.K.4
Gupta, A.5
Funk, M.6
Pandita, T.K.7
-
17
-
-
33745330907
-
Overexpressed heat shock protein 70 protects cells against DNA damage caused by ultraviolet C in a dose-dependent manner
-
Niu P,Liu L,Gong Z,Tan H,Wang F,Yuan J,Feng Y,Wei Q,Tanguay RM,Wu T.Overexpressed heat shock protein 70 protects cells against DNA damage caused by ultraviolet C in a dose-dependent manner.Cell Stress Chaperones. 2006;11:162-9.
-
(2006)
Cell Stress Chaperones
, vol.11
, pp. 162-169
-
-
Niu, P.1
Liu, L.2
Gong, Z.3
Tan, H.4
Wang, F.5
Yuan, J.6
Feng, Y.7
Wei, Q.8
Tanguay, R.M.9
Wu, T.10
-
18
-
-
77958516062
-
ATPases as drug targets: insights from heat shock proteins 70 and 90
-
Massey AJ.ATPases as drug targets: insights from heat shock proteins 70 and 90.J Med Chem. 2010;53:7280-6.
-
(2010)
J Med Chem
, vol.53
, pp. 7280-7286
-
-
Massey, A.J.1
-
19
-
-
84864029423
-
Antileukemic activity of the HSP70 inhibitor pifithrin-mu in acute leukemia
-
Kaiser M,Kuhnl A,Reins J,Fischer S,Ortiz-Tanchez J,Schlee C,Mochmann LH,Heesch S,Benlasfer O,Hofmann WK,Thiel E,Baldus CD.Antileukemic activity of the HSP70 inhibitor pifithrin-mu in acute leukemia.Blood Cancer J. 2011;1:e28-e28.
-
(2011)
Blood Cancer J
, vol.1
-
-
Kaiser, M.1
Kuhnl, A.2
Reins, J.3
Fischer, S.4
Ortiz-Tanchez, J.5
Schlee, C.6
Mochmann, L.H.7
Heesch, S.8
Benlasfer, O.9
Hofmann, W.K.10
Thiel, E.11
Baldus, C.D.12
-
20
-
-
64349121987
-
Novel adenosine-derived inhibitors of 70 kDa heat shock protein, discovered through structure-based design
-
Williamson DS,Borgognoni J,Clay A,Daniels Z,Dokurno P,Drysdale MJ,Foloppe N,Francis GL,Graham CJ,Howes R,Macias AT,Murray JB,Parsons R,Shaw T,Surgenor AE,Terry L,Wang Y,Wood M,Massey AJ.Novel adenosine-derived inhibitors of 70 kDa heat shock protein, discovered through structure-based design.J Med Chem. 2009;52:1510-3.
-
(2009)
J Med Chem
, vol.52
, pp. 1510-1513
-
-
Williamson, D.S.1
Borgognoni, J.2
Clay, A.3
Daniels, Z.4
Dokurno, P.5
Drysdale, M.J.6
Foloppe, N.7
Francis, G.L.8
Graham, C.J.9
Howes, R.10
Macias, A.T.11
Murray, J.B.12
Parsons, R.13
Shaw, T.14
Surgenor, A.E.15
Terry, L.16
Wang, Y.17
Wood, M.18
Massey, A.J.19
-
21
-
-
84879589788
-
The PI3K/Akt signalling pathway regulates the expression of Hsp70, which critically contributes to Hsp90-chaperone function and tumor cell survival in multiple myeloma
-
Chatterjee M,Andrulis M,Stuhmer T,Muller E,Hofmann C,Steinbrunn T,Heimberger T,Schraud H,Kressmann S,Einsele H,Bargou RC.The PI3K/Akt signalling pathway regulates the expression of Hsp70, which critically contributes to Hsp90-chaperone function and tumor cell survival in multiple myeloma.Haematologica. 2012;98:1132-41.
-
(2012)
Haematologica
, vol.98
, pp. 1132-1141
-
-
Chatterjee, M.1
Andrulis, M.2
Stuhmer, T.3
Muller, E.4
Hofmann, C.5
Steinbrunn, T.6
Heimberger, T.7
Schraud, H.8
Kressmann, S.9
Einsele, H.10
Bargou, R.C.11
-
22
-
-
77954662908
-
A novel, small molecule inhibitor of Hsc70/Hsp70 potentiates Hsp90 inhibitor induced apoptosis in HCT116 colon carcinoma cells
-
Massey AJ,Williamson DS,Browne H,Murray JB,Dokurno P,Shaw T,Macias AT,Daniels Z,Geoffroy S,Dopson M,Lavan P,Matassova N,Francis GL,Graham CJ,Parsons R,Wang Y,Padfield A,Comer M,Drysdale MJ,Wood M.A novel, small molecule inhibitor of Hsc70/Hsp70 potentiates Hsp90 inhibitor induced apoptosis in HCT116 colon carcinoma cells.Cancer Chemother Pharmacol. 2010;66:535-45.
-
(2010)
Cancer Chemother Pharmacol
, vol.66
, pp. 535-545
-
-
Massey, A.J.1
Williamson, D.S.2
Browne, H.3
Murray, J.B.4
Dokurno, P.5
Shaw, T.6
Macias, A.T.7
Daniels, Z.8
Geoffroy, S.9
Dopson, M.10
Lavan, P.11
Matassova, N.12
Francis, G.L.13
Graham, C.J.14
Parsons, R.15
Wang, Y.16
Padfield, A.17
Comer, M.18
Drysdale, M.J.19
Wood, M.20
more..
-
23
-
-
0031873752
-
The 90-kDa molecular chaperone family: structure, function, and clinical applications. A Comprehensive Review
-
Csermely P,Schnaider T,Soti C,Prohaszka Z,Nardai G.The 90-kDa molecular chaperone family: structure, function, and clinical applications.A comprehensive review. Pharmacol Ther. 1998;79:129-68.
-
(1998)
Pharmacol Ther
, vol.79
, pp. 129-168
-
-
Csermely, P.1
Schnaider, T.2
Soti, C.3
Prohaszka, Z.4
Nardai, G.5
-
24
-
-
0034957003
-
The Drosophila Dpit47 protein is a nuclear Hsp90 co-chaperone that interacts with DNA polymerase alpha
-
Crevel G,Bates H,Huikeshoven H,Cotterill S.The Drosophila Dpit47 protein is a nuclear Hsp90 co-chaperone that interacts with DNA polymerase alpha.J Cell Sci. 2001;114 (Pt 11): 2015-25.
-
(2001)
J Cell Sci
, vol.114
, Issue.Pt 11
, pp. 2015-2025
-
-
Crevel, G.1
Bates, H.2
Huikeshoven, H.3
Cotterill, S.4
-
25
-
-
84878964181
-
The HSP70 family and cancer
-
Murphy ME.The HSP70 family and cancer.Carcinogenesis. 2013;34:1181-8.
-
(2013)
Carcinogenesis
, vol.34
, pp. 1181-1188
-
-
Murphy, M.E.1
-
26
-
-
75549083827
-
EGFR signaling and drug discovery
-
Lurje G,Lenz HJ.EGFR signaling and drug discovery.Oncology. 2009;77:400-10.
-
(2009)
Oncology
, vol.77
, pp. 400-410
-
-
Lurje, G.1
Lenz, H.J.2
-
27
-
-
0037131187
-
Akt forms an intracellular complex with heat shock protein 90 (Hsp90) and Cdc37 and is destabilized by inhibitors of Hsp90 function
-
Basso AD,Solit DB,Chiosis G,Giri B,Tsichlis P,Rosen N.Akt forms an intracellular complex with heat shock protein 90 (Hsp90) and Cdc37 and is destabilized by inhibitors of Hsp90 function.J Biol Chem. 2002;277:39858-66.
-
(2002)
J Biol Chem
, vol.277
, pp. 39858-39866
-
-
Basso, A.D.1
Solit, D.B.2
Chiosis, G.3
Giri, B.4
Tsichlis, P.5
Rosen, N.6
-
29
-
-
84858290309
-
Disease-stabilizing treatment with all-trans retinoic acid and valproic acid in acute myeloid leukemia: serum hsp70 and hsp90 levels and serum cytokine profiles are determined by the disease, patient age, and anti-leukemic treatment
-
Fredly H,Reikvam H,Gjertsen BT,Bruserud O.Disease-stabilizing treatment with all-trans retinoic acid and valproic acid in acute myeloid leukemia: serum hsp70 and hsp90 levels and serum cytokine profiles are determined by the disease, patient age, and anti-leukemic treatment.Am J Hematol. 2012;87:368-76.
-
(2012)
Am J Hematol
, vol.87
, pp. 368-376
-
-
Fredly, H.1
Reikvam, H.2
Gjertsen, B.T.3
Bruserud, O.4
-
30
-
-
84862883702
-
Immunohistochemical evaluation of expression of heat shock proteins HSP70 and HSP90 in mammary gland neoplasms in bitches
-
Badowska-Kozakiewicz AM,Malicka E.Immunohistochemical evaluation of expression of heat shock proteins HSP70 and HSP90 in mammary gland neoplasms in bitches.Pol J Vet Sci. 2012;15:209-14.
-
(2012)
Pol J Vet Sci
, vol.15
, pp. 209-214
-
-
Badowska-Kozakiewicz, A.M.1
Malicka, E.2
-
31
-
-
84863562310
-
Alterations of the Hsp70/Hsp90 chaperone and the HOP/CHIP co-chaperone system in cancer
-
Ruckova E,Muller P,Nenutil R,Vojtesek B.Alterations of the Hsp70/Hsp90 chaperone and the HOP/CHIP co-chaperone system in cancer.Cell Mol Biol Lett. 2012;17:446-58.
-
(2012)
Cell Mol Biol Lett
, vol.17
, pp. 446-458
-
-
Ruckova, E.1
Muller, P.2
Nenutil, R.3
Vojtesek, B.4
-
32
-
-
84885050263
-
Hsp70 silencing with siRNA in nanocarriers enhances cancer cell death induced by the inhibitor of Hsp90
-
Matokanovic M,Barisic K,Filipovic-Grcic J,Maysinger D.Hsp70 silencing with siRNA in nanocarriers enhances cancer cell death induced by the inhibitor of Hsp90.Eur J Pharm Sci. 2013;50:149-58.
-
(2013)
Eur J Pharm Sci
, vol.50
, pp. 149-158
-
-
Matokanovic, M.1
Barisic, K.2
Filipovic-Grcic, J.3
Maysinger, D.4
-
33
-
-
84861829464
-
Co-inhibition of HSP70/HSP90 synergistically sensitizes nasopharyngeal carcinoma cells to thermotherapy
-
Cui XB,Yu ZY,Wang W,Zheng YQ,Liu W,Li LX.Co-inhibition of HSP70/HSP90 synergistically sensitizes nasopharyngeal carcinoma cells to thermotherapy.Integr Cancer Ther. 2012;11:61-7.
-
(2012)
Integr Cancer Ther
, vol.11
, pp. 61-67
-
-
Cui, X.B.1
Yu, Z.Y.2
Wang, W.3
Zheng, Y.Q.4
Liu, W.5
Li, L.X.6
-
34
-
-
33644500163
-
Domain:domain interactions within Hop, the Hsp70/Hsp90 organizing protein, are required for protein stability and structure
-
Carrigan PE,Sikkink LA,Smith DF,Ramirez-Alvarado M.Domain:domain interactions within Hop, the Hsp70/Hsp90 organizing protein, are required for protein stability and structure.Protein Sci. 2006;15:522-32.
-
(2006)
Protein Sci
, vol.15
, pp. 522-532
-
-
Carrigan, P.E.1
Sikkink, L.A.2
Smith, D.F.3
Ramirez-Alvarado, M.4
-
35
-
-
78149465156
-
Increased expression of co-chaperone HOP with HSP90 and HSC70 and complex formation in human colonic carcinoma
-
Kubota H,Yamamoto S,Itoh E,Abe Y,Nakamura A,Izumi Y,Okada H,Iida M,Nanjo H,Itoh H,Yamamoto Y.Increased expression of co-chaperone HOP with HSP90 and HSC70 and complex formation in human colonic carcinoma.Cell Stress Chaperones. 2010;15:1003-11.
-
(2010)
Cell Stress Chaperones
, vol.15
, pp. 1003-1011
-
-
Kubota, H.1
Yamamoto, S.2
Itoh, E.3
Abe, Y.4
Nakamura, A.5
Izumi, Y.6
Okada, H.7
Iida, M.8
Nanjo, H.9
Itoh, H.10
Yamamoto, Y.11
-
36
-
-
35648963627
-
Proteome analysis of hepatocellular carcinoma by two-dimensional difference gel electrophoresis: novel protein markers in hepatocellular carcinoma tissues
-
Sun W,Xing B,Sun Y,Du X,Lu M,Hao C,Lu Z,Mi W,Wu S,Wei H,Gao X,Zhu Y,Jiang Y,Qian X,He F.Proteome analysis of hepatocellular carcinoma by two-dimensional difference gel electrophoresis: novel protein markers in hepatocellular carcinoma tissues.Mol Cell Proteomics. 2007;6:1798-808.
-
(2007)
Mol Cell Proteomics
, vol.6
, pp. 1798-1808
-
-
Sun, W.1
Xing, B.2
Sun, Y.3
Du, X.4
Lu, M.5
Hao, C.6
Lu, Z.7
Mi, W.8
Wu, S.9
Wei, H.10
Gao, X.11
Zhu, Y.12
Jiang, Y.13
Qian, X.14
He, F.15
-
37
-
-
79955478704
-
RNAi knockdown of Hop (Hsp70/Hsp90 organising protein) decreases invasion via MMP-2 down regulation
-
Walsh N,Larkin A,Swan N,Conlon K,Dowling P,McDermott R,Clynes M.RNAi knockdown of Hop (Hsp70/Hsp90 organising protein) decreases invasion via MMP-2 down regulation.Cancer Lett. 2011;306:180-9.
-
(2011)
Cancer Lett
, vol.306
, pp. 180-189
-
-
Walsh, N.1
Larkin, A.2
Swan, N.3
Conlon, K.4
Dowling, P.5
McDermott, R.6
Clynes, M.7
-
38
-
-
84899668980
-
Molecular cochaperones: tumor growth and cancer treatment
-
Calderwood SK.Molecular cochaperones: tumor growth and cancer treatment.Scientifica. 2013;2013:217513-217513.
-
(2013)
Scientifica
, vol.2013
, pp. 217513
-
-
Calderwood, S.K.1
|