The STAT3 HIES mutation is a gain-of-function mutation that activates genes via AGG-element carrying promoters

Nucleic Acids Research

Volumn 43, Issue 18, 2015, Pages 8898-8912

  Xu, Li ^a   Ji, Jin Jun ^a   Le, Wangping ^b   Xu, Yan S ^c   Dou, Dandan ^c   Pan, Jieli ^a   Jiao, Yifeng ^a   Zhong, Tianfei ^a   Wu, Dehong ^a   Wang, Yumei ^b   Wen, Chengping ^a   Xie, Guan Qun ^a   Yao, Feng ^d   Zhao, Heng ^d   Fan, Yong Sheng ^a   Chin, Y Eugene ^a,b  

^a ZHEJIANG CHINESE MEDICAL UNIVERSITY   (China)

^b SHANGHAI JIAO TONG UNIVERSITY SCHOOL OF MEDICINE   (China)

^c SHANDONG UNIVERSITY SCHOOL OF MEDICINE   (China)

^d SHANGHAI JIAO TONG UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

MYC PROTEIN; STAT3 PROTEIN; TUMOR NECROSIS FACTOR;

AGG ELEMENT; AMINO TERMINAL SEQUENCE; ARTICLE; BINDING SITE; CELLULAR DISTRIBUTION; CONTROLLED STUDY; DNA BINDING DOMAIN; DNA SEQUENCE; GAIN OF FUNCTION MUTATION; GENE ACTIVATION; GENE CONTROL; GENE EXPRESSION; HYPER IGE SYNDROME; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN DNA BINDING; PROTEIN DOMAIN; PROTEIN LOCALIZATION; PROTEIN PROCESSING; PROTEIN STRUCTURE; TRANSCRIPTION INITIATION; TRANSCRIPTION REGULATION; ANIMAL; CELL LINE; CHEMISTRY; CONSENSUS SEQUENCE; GENETICS; HUMAN; METABOLISM; MOUSE; MUTATION; NUCLEOTIDE MOTIF; NUCLEOTIDE SEQUENCE;

ANIMALS; BASE SEQUENCE; BINDING SITES; CELL LINE; CONSENSUS SEQUENCE; HUMANS; JOB SYNDROME; MICE; MUTATION; NUCLEOTIDE MOTIFS; PROMOTER REGIONS, GENETIC; PROTEIN PROCESSING, POST-TRANSLATIONAL; STAT3 TRANSCRIPTION FACTOR; TRANSCRIPTIONAL ACTIVATION; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84965002107     PISSN: 03051048     EISSN: 13624962     Source Type: Journal    
DOI: 10.1093/nar/gkv911     Document Type: Article

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