SHP-2 is a dual-specificity phosphatase involved in Stat1 dephosphorylation at both tyrosine and serine residues in nuclei

Journal of Biological Chemistry

Volumn 277, Issue 49, 2002, Pages 47572-47580

  Wu, Tong R ^a   Kate Hong, Y ^a   Wang, Xu Dong ^a   Ling, Mike Y ^a   Dragoi, Ana M ^a   Chung, Alicia S ^a   Campbell, Andrew G ^a   Han, Zhi Yong ^a   Feng, Gen Sheng ^b   Chin, Y Eugene ^a  

^a BROWN UNIVERSITY   (United States)

^b BURNHAM INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBODIES; ASSAYS; ENZYMES; GENES; PROTEINS;

DEPHOSPHORYLATION; SERINE RESIDUES;

BIOCHEMISTRY;

EPIDERMAL GROWTH FACTOR; GAMMA INTERFERON; PHOSPHATASE; PROTEIN; PROTEIN TYROSINE PHOSPHATASE SHP 2; SERINE; STAT1 PROTEIN; TYROSINE; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; BINDING AFFINITY; CARBOXY TERMINAL SEQUENCE; CELL NUCLEUS; CELLULAR DISTRIBUTION; CONTROLLED STUDY; DEPHOSPHORYLATION; ENZYME ACTIVITY; FIBROBLAST; GENE CONTROL; IMMUNOFLUORESCENCE TEST; IMMUNOPRECIPITATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN INDUCTION; PROTEIN MODIFICATION; PROTEIN PROTEIN INTERACTION; SIGNAL TRANSDUCTION; TRANSCRIPTION INITIATION;

ACTIVE TRANSPORT, CELL NUCLEUS; AMINO ACID SEQUENCE; ANIMALS; CELL LINE; CELL NUCLEUS; CELLS, CULTURED; DNA; DNA, COMPLEMENTARY; DNA-BINDING PROTEINS; DOSE-RESPONSE RELATIONSHIP, DRUG; ELECTROPHORESIS, POLYACRYLAMIDE GEL; FIBROBLASTS; GENE EXPRESSION REGULATION; GLUTATHIONE TRANSFERASE; HUMANS; INTERFERON TYPE II; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; LUCIFERASES; MICE; MICROSCOPY, FLUORESCENCE; MOLECULAR SEQUENCE DATA; PHOSPHORYLATION; PRECIPITIN TESTS; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; PROTEIN-TYROSINE-PHOSPHATASE; SEQUENCE HOMOLOGY, AMINO ACID; SERINE; STAT1 TRANSCRIPTION FACTOR; TIME FACTORS; TRANS-ACTIVATORS; TUMOR CELLS, CULTURED; TYROSINE;

ANIMALIA;

EID: 0037033046     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M207536200     Document Type: Article

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