An antibody biosensor establishes the activation of the M1 muscarinic acetylcholine receptor during learning and memory

Journal of Biological Chemistry

Volumn 291, Issue 17, 2016, Pages 8862-8875

  Butcher, Adrian J ^a,c   Bradley, Sophie J ^a   Prihandoko, Rudi ^a   Brooke, Simon M ^a   Mogg, Adrian ^b   Bourgognon, Julie Myrtille ^a   Macedo Hatch, Timothy ^a   Edwards, Jennifer M ^a   Bottrill, Andrew R ^a   Challiss, R A John ^a   Broad, Lisa M ^b   Felder, Christian C ^b   Tobin, Andrew B ^a  

^a UNIVERSITY OF LEICESTER   (United Kingdom)

^b ELI LILLY AND COMPANY   (United States)

^c UNIVERSITY OF GLASGOW   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVATION ANALYSIS; AMINO ACIDS; BIOSENSORS; CHEMICAL ACTIVATION; DRUG PRODUCTS; DRUG THERAPY; MASS SPECTROMETRY; MODULATORS; PHOSPHORYLATION;

G PROTEIN COUPLED RECEPTORS; LEARNING AND MEMORY; MEMORY ACQUISITIONS; MUSCARINIC ACETYLCHOLINE RECEPTORS; NEURONAL ACTIVITIES; PHOSPHOSPECIFIC ANTIBODIES; PHYSIOLOGICAL ROLES; POSITIVE ALLOSTERIC MODULATOR;

ANTIBODIES;

MUSCARINIC M1 RECEPTOR; MONOCLONAL ANTIBODY; PHOSPHOPROTEIN;

ALLOSTERISM; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTIBODY BIOSENSOR; ARTICLE; BIOSENSOR; CHO CELL LINE; CONTROLLED STUDY; FEMALE; HIPPOCAMPAL CA1 REGION; IMMUNOREACTIVITY; IN VITRO STUDY; IN VIVO STUDY; LEARNING; MALE; MASS SPECTROMETRY; MEMORY; MEMORY CONSOLIDATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN PHOSPHORYLATION; RECEPTOR UPREGULATION; ANIMAL; CHEMISTRY; CRICETULUS; CYTOLOGY; GENETIC PROCEDURES; GENETICS; HAMSTER; METABOLISM; PHOSPHORYLATION; PHYSIOLOGY; PROCEDURES;

ANIMALS; ANTIBODIES, MONOCLONAL, MURINE-DERIVED; BIOSENSING TECHNIQUES; CA1 REGION, HIPPOCAMPAL; CHO CELLS; CRICETINAE; CRICETULUS; LEARNING; MEMORY; MICE; PHOSPHOPROTEINS; PHOSPHORYLATION; RECEPTOR, MUSCARINIC M1;

EID: 84964904479     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M115.681726     Document Type: Article

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