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Volumn 27, Issue 9, 2016, Pages 1420-1430

Tension on JAM-A activates RhoA via GEF-H1 and p115 RhoGEF

Author keywords

[No Author keywords available]

Indexed keywords

FOCAL ADHESION KINASE; JUNCTIONAL ADHESION MOLECULE A; MITOGEN ACTIVATED PROTEIN KINASE; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN TYROSINE KINASE; RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR; RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR H1; RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR P115; RHOA GUANINE NUCLEOTIDE BINDING PROTEIN; SERINE; UNCLASSIFIED DRUG; ARHGEF1 PROTEIN, HUMAN; ARHGEF2 PROTEIN, HUMAN; CELL ADHESION MOLECULE; GUANINE NUCLEOTIDE EXCHANGE FACTOR;

EID: 84964859117     PISSN: 10591524     EISSN: 19394586     Source Type: Journal    
DOI: 10.1091/mbc.E15-12-0833     Document Type: Article
Times cited : (39)

References (74)
  • 1
    • 38749148787 scopus 로고    scopus 로고
    • Interaction of transient receptor potential vanilloid 4, integrin, and SRC tyrosine kinase in mechanical hyperalgesia
    • Alessandri-Haber N, Dina OA, Joseph EK, Reichling DB, Levine JD (2008). Interaction of transient receptor potential vanilloid 4, integrin, and SRC tyrosine kinase in mechanical hyperalgesia. J Neurosci 28, 1046-1057.
    • (2008) J Neurosci , vol.28 , pp. 1046-1057
    • Alessandri-Haber, N.1    Dina, O.A.2    Joseph, E.K.3    Reichling, D.B.4    Levine, J.D.5
  • 2
    • 0035951873 scopus 로고    scopus 로고
    • JAM-2, a novel immunoglobulin superfamily molecule, expressed by endothelial and lymphatic cells
    • Aurrand-Lions M, Duncan L, Ballestrem C, Imhof BA (2001a). JAM-2, a novel immunoglobulin superfamily molecule, expressed by endothelial and lymphatic cells. J Biol Chem 276, 2733-2741.
    • (2001) J Biol Chem , vol.276 , pp. 2733-2741
    • Aurrand-Lions, M.1    Duncan, L.2    Ballestrem, C.3    Imhof, B.A.4
  • 3
    • 0035895050 scopus 로고    scopus 로고
    • Heterogeneity of endothelial junctions is refected by differential expression and specifc subcellular localization of the three JAM family members
    • Aurrand-Lions M, Johnson-Leger C, Wong C, Du Pasquier L, Imhof BA (2001b). Heterogeneity of endothelial junctions is refected by differential expression and specifc subcellular localization of the three JAM family members. Blood 98, 3699-3707.
    • (2001) Blood , vol.98 , pp. 3699-3707
    • Aurrand-Lions, M.1    Johnson-Leger, C.2    Wong, C.3    Du Pasquier, L.4    Imhof, B.A.5
  • 4
    • 84928662556 scopus 로고    scopus 로고
    • Local VE-cadherin mechanotrans-duction triggers long-ranged remodeling of endothelial monolayers
    • Barry AK, Wang N, Leckband DE (2015). Local VE-cadherin mechanotrans-duction triggers long-ranged remodeling of endothelial monolayers. J Cell Sci 128, 1341-1351.
    • (2015) J Cell Sci , vol.128 , pp. 1341-1351
    • Barry, A.K.1    Wang, N.2    De, L.3
  • 7
    • 0034458943 scopus 로고    scopus 로고
    • SU6656, a selective src family kinase inhibitor, used to probe growth factor signaling
    • Blake RA, Broome MA, Liu X, Wu J, Gishizky M, Sun L, Courtneidge SA (2000). SU6656, a selective src family kinase inhibitor, used to probe growth factor signaling. Mol Cell Biol 20, 9018-9027.
    • (2000) Mol Cell Biol , vol.20 , pp. 9018-9027
    • Blake, R.A.1    Ma, B.2    Liu, X.3    Wu, J.4    Gishizky, M.5    Sun, L.6    Courtneidge, S.A.7
  • 10
    • 34250671560 scopus 로고    scopus 로고
    • Src and focal adhesion kinase mediate mechanical strain-induced proliferation and ERK1/2 phos-phorylation in human H441 pulmonary epithelial cells
    • Chaturvedi LS, Marsh HM, Basson MD (2007). Src and focal adhesion kinase mediate mechanical strain-induced proliferation and ERK1/2 phos-phorylation in human H441 pulmonary epithelial cells. Am J Physiol Cell Physiol 292, C1701-C1713.
    • (2007) Am J Physiol Cell Physiol , vol.292 , pp. C1701-C1713
    • Chaturvedi, L.S.1    Marsh, H.M.2    Basson, M.D.3
  • 11
    • 50249131363 scopus 로고    scopus 로고
    • Mechanotransduction in an extracted cell model: Fyn drives stretch-And fow-elicited PECAM-1 phosphorylation
    • Chiu YJ, McBeath E, Fujiwara K (2008). Mechanotransduction in an extracted cell model: Fyn drives stretch-And fow-elicited PECAM-1 phosphorylation. J Cell Biol 182, 753-763.
    • (2008) J Cell Biol , vol.182 , pp. 753-763
    • Chiu, Y.J.1    McBeath, E.2    Fujiwara, K.3
  • 12
    • 32144460477 scopus 로고    scopus 로고
    • C-terminal Src kinase (CSK) and CSK-homologous kinase (CHK)-endogenous negative regulators of Src-family protein kinases
    • Chong YP, Mulhern TD, Cheng HC (2005). C-terminal Src kinase (CSK) and CSK-homologous kinase (CHK)-endogenous negative regulators of Src-family protein kinases. Growth Factors 23, 233-244.
    • (2005) Growth Factors , vol.23 , pp. 233-244
    • Chong, Y.P.1    Mulhern, T.D.2    Cheng, H.C.3
  • 13
    • 0029995797 scopus 로고    scopus 로고
    • Rho-stimulated contractility drives the formation of stress fbers and focal adhesions
    • Chrzanowska-Wodnicka M, Burridge K (1996). Rho-stimulated contractility drives the formation of stress fbers and focal adhesions. J Cell Biol 133, 1403-1415.
    • (1996) J Cell Biol , vol.133 , pp. 1403-1415
    • Chrzanowska-Wodnicka, M.1    Burridge, K.2
  • 14
    • 84869500245 scopus 로고    scopus 로고
    • Localized tensional forces on PECAM-1 elicit a global mechanotransduction response via the integrin-RhoA pathway
    • Collins C, Guilluy C, Welch C, O'Brien ET, Hahn K, Superfne R, Burridge K, Tzima E (2012). Localized tensional forces on PECAM-1 elicit a global mechanotransduction response via the integrin-RhoA pathway. Curr Biol 22, 2087-2094.
    • (2012) Curr Biol , vol.22 , pp. 2087-2094
    • Collins, C.1    Guilluy, C.2    Welch, C.3    O'Brien, E.T.4    Hahn, K.5    Superfne, R.6    Burridge, K.7    Tzima, E.8
  • 16
    • 0037092517 scopus 로고    scopus 로고
    • Sequential activation of individual PKC isozymes in integrin-mediated muscle cell spreading: A role for MARCKS in an integrin signaling pathway
    • Disatnik MH, Boutet SC, Lee CH, Mochly-Rosen D, Rando TA (2002). Sequential activation of individual PKC isozymes in integrin-mediated muscle cell spreading: a role for MARCKS in an integrin signaling pathway. J Cell Sci 115, 2151-2163.
    • (2002) J Cell Sci , vol.115 , pp. 2151-2163
    • Disatnik, M.H.1    Boutet, S.C.2    Ch, L.3    Mochly-Rosen, D.4    Rando, T.A.5
  • 17
    • 33746918654 scopus 로고    scopus 로고
    • PKCbeta-dependent activation of RhoA by syndecan-4 during focal adhesion formation
    • Dovas A, Yoneda A, Couchman JR (2006). PKCbeta-dependent activation of RhoA by syndecan-4 during focal adhesion formation. J Cell Sci 119, 2837-2846.
    • (2006) J Cell Sci , vol.119 , pp. 2837-2846
    • Dovas, A.1    Yoneda, A.2    Couchman, J.R.3
  • 18
    • 37249071435 scopus 로고    scopus 로고
    • A novel role for Lsc/p115 RhoGEF and LARG in regulating RhoA activity downstream of adhesion to fbronectin
    • Dubash AD, Wennerberg K, Garcia-Mata R, Menold MM, Arthur WT, Burridge K (2007). A novel role for Lsc/p115 RhoGEF and LARG in regulating RhoA activity downstream of adhesion to fbronectin. J Cell Sci 120, 3989-3998.
    • (2007) J Cell Sci , vol.120 , pp. 3989-3998
    • Dubash, A.D.1    Wennerberg, K.2    Garcia-Mata, R.3    Menold, M.M.4    Arthur, W.T.5    Burridge, K.6
  • 19
    • 84980383740 scopus 로고    scopus 로고
    • Conformational coupling of integrin and Thy-1 regulates Fyn priming and fbroblast mechanotransduction
    • Fiore VF, Strane PW, Bryksin AV, White ES, Hagood JS, Barker TH (2015). Conformational coupling of integrin and Thy-1 regulates Fyn priming and fbroblast mechanotransduction. J Cell Biol 211, 173-190.
    • (2015) J Cell Biol , vol.211 , pp. 173-190
    • Fiore, V.F.1    Strane, P.W.2    Bryksin, A.V.3    White, E.S.4    Hagood, J.S.5    Barker, T.H.6
  • 23
    • 84861738385 scopus 로고    scopus 로고
    • Analysis of RhoA and Rho GEF activity in whole cells and the cell nucleus
    • Guilluy C, Dubash AD, Garcia-Mata R (2011a). Analysis of RhoA and Rho GEF activity in whole cells and the cell nucleus. Nat Protoc 6, 2050-2060.
    • (2011) Nat Protoc , vol.6 , pp. 2050-2060
    • Guilluy, C.1    Dubash, A.D.2    Garcia-Mata, R.3
  • 25
    • 84901457450 scopus 로고    scopus 로고
    • Rho-GTPase signaling in leukocyte extravasation: An endothelial point of view
    • Heemskerk N, van Rijssel J, van Buul JD (2014). Rho-GTPase signaling in leukocyte extravasation: an endothelial point of view. Cell Adh Migr 8, 67-75.
    • (2014) Cell Adh Migr , vol.8 , pp. 67-75
    • Heemskerk, N.1    Van Rijssel, J.2    Van Buul, J.D.3
  • 27
    • 84912102132 scopus 로고    scopus 로고
    • Low junctional adhesion molecule A expression correlates with poor prognosis in gastric cancer
    • Huang JY, Xu YY, Sun Z, Wang ZN, Zhu Z, Song YX, Luo Y, Zhang X, Xu HM (2014). Low junctional adhesion molecule A expression correlates with poor prognosis in gastric cancer. J Surg Res 192, 494-502.
    • (2014) J Surg Res , vol.192 , pp. 494-502
    • Huang, J.Y.1    Xu, Y.Y.2    Sun, Z.3    Wang, Z.N.4    Zhu, Z.5    Song, Y.X.6    Luo, Y.7    Zhang, X.8    Xu, H.M.9
  • 30
    • 33744772918 scopus 로고    scopus 로고
    • Fibronectin rigidity response through Fyn and p130Cas recruitment to the leading edge
    • Kostic A, Sheetz MP (2006). Fibronectin rigidity response through Fyn and p130Cas recruitment to the leading edge. Mol Biol Cell 17, 2684-2695.
    • (2006) Mol Biol Cell , vol.17 , pp. 2684-2695
    • Kostic, A.1    Sheetz, M.P.2
  • 31
    • 84868348777 scopus 로고    scopus 로고
    • Effects of JAMA defciency or blocking antibodies on neutrophil migration and lung injury in a murine model of ALI
    • Lakshmi S P, Reddy AT, Naik MU, Naik U P, Reddy RC (2012). Effects of JAMA defciency or blocking antibodies on neutrophil migration and lung injury in a murine model of ALI. Am J Physiol Lung Cell Mol Physiol 303, L758-L766.
    • (2012) Am J Physiol Lung Cell Mol Physiol , vol.303 , pp. L758-L766
    • Lakshmi, S.P.1    Reddy, A.T.2    Naik, M.U.3    Naik, U.P.4    Reddy, R.C.5
  • 32
    • 84866680424 scopus 로고    scopus 로고
    • From mechanical force to RhoA activation
    • Lessey EC, Guilluy C, Burridge K (2012). From mechanical force to RhoA activation. Biochemistry 51, 7420-7432.
    • (2012) Biochemistry , vol.51 , pp. 7420-7432
    • Lessey, E.C.1    Guilluy, C.2    Burridge, K.3
  • 33
    • 84897551177 scopus 로고    scopus 로고
    • The RhoA guanine nucleotide exchange factor, LARG, mediates ICAM-1-dependent mechanotrans-duction in endothelial cells to stimulate transendothelial migration
    • Lessey-Morillon EC, Osborne LD, Monaghan-Benson E, Guilluy C, O'Brien ET, Superfne R, Burridge K (2014). The RhoA guanine nucleotide exchange factor, LARG, mediates ICAM-1-dependent mechanotrans-duction in endothelial cells to stimulate transendothelial migration. J Immunol 192, 3390-3398.
    • (2014) J Immunol , vol.192 , pp. 3390-3398
    • Lessey-Morillon, E.C.1    Osborne, L.D.2    Monaghan-Benson, E.3    Guilluy, C.4    O'Brien, E.T.5    Superfne, R.6    Burridge, K.7
  • 34
    • 77950189784 scopus 로고    scopus 로고
    • Mechanical forces in endothelial cells during frm adhesion and early transmigration of human monocytes
    • Liu Z, Sniadecki NJ, Chen CS (2010). Mechanical forces in endothelial cells during frm adhesion and early transmigration of human monocytes. Cell Mol Bioeng 3, 50-59.
    • (2010) Cell Mol Bioeng , vol.3 , pp. 50-59
    • Liu, Z.1    Sniadecki, N.J.2    Chen, C.S.3
  • 35
    • 1942501686 scopus 로고    scopus 로고
    • Involvement of the junctional adhesion molecule-1 (JAM1) homodimer interface in regulation of epithelial barrier function
    • Mandell KJ, McCall IC, Parkos CA (2004). Involvement of the junctional adhesion molecule-1 (JAM1) homodimer interface in regulation of epithelial barrier function. J Biol Chem 279, 16254-16262.
    • (2004) J Biol Chem , vol.279 , pp. 16254-16262
    • Mandell, K.J.1    McCall, I.C.2    Parkos, C.A.3
  • 36
    • 84896699258 scopus 로고    scopus 로고
    • Regulation of RhoA activity by adhesion molecules and mechanotransduction
    • Marjoram RJ, Lessey EC, Burridge K (2014). Regulation of RhoA activity by adhesion molecules and mechanotransduction. Curr Mol Med 14, 199-208.
    • (2014) Curr Mol Med , vol.14 , pp. 199-208
    • Marjoram, R.J.1    Lessey, E.C.2    Burridge, K.3
  • 37
    • 2642614521 scopus 로고    scopus 로고
    • Junctional adhesion molecule, a novel member of the immunoglobulin superfamily that distributes at intercellular junctions and modulates monocyte transmigration
    • Martin-Padura I, Lostaglio S, Schneemann M, Williams L, Romano M, Fruscella P, Panzeri C, Stoppacciaro A, Ruco L, Villa A, et al. (1998). Junctional adhesion molecule, a novel member of the immunoglobulin superfamily that distributes at intercellular junctions and modulates monocyte transmigration. J Cell Biol 142, 117-127.
    • (1998) J Cell Biol , vol.142 , pp. 117-127
    • Martin-Padura, I.1    Lostaglio, S.2    Schneemann, M.3    Williams, L.4    Romano, M.5    Fruscella, P.6    Panzeri, C.7    Stoppacciaro, A.8    Ruco, L.9    Villa, A.10
  • 39
    • 33644967727 scopus 로고    scopus 로고
    • Cellular adaptation to mechanical stress: Role of integrins, Rho, cytoskeletal tension and mechanosensitive ion channels
    • Matthews BD, Overby DR, Mannix R, Ingber DE (2006). Cellular adaptation to mechanical stress: role of integrins, Rho, cytoskeletal tension and mechanosensitive ion channels. J Cell Sci 119, 508-518.
    • (2006) J Cell Sci , vol.119 , pp. 508-518
    • Matthews, B.D.1    Overby, D.R.2    Mannix, R.3    De, I.4
  • 42
    • 84861970173 scopus 로고    scopus 로고
    • Intracellular mediators of JAM-A-depen-dent epithelial barrier function
    • Monteiro AC, Parkos CA (2012). Intracellular mediators of JAM-A-depen-dent epithelial barrier function. Ann NY Acad Sci 1257, 115-124.
    • (2012) Ann NY Acad Sci , vol.1257 , pp. 115-124
    • Monteiro, A.C.1    Parkos, C.A.2
  • 44
    • 84899677468 scopus 로고    scopus 로고
    • Junctional adhesion molecule-A suppresses platelet integrin alphaIIbbeta3 signaling by recruiting Csk to the integrin-c-Src complex
    • Naik MU, Caplan JL, Naik UP (2014). Junctional adhesion molecule-A suppresses platelet integrin alphaIIbbeta3 signaling by recruiting Csk to the integrin-c-Src complex. Blood 123, 1393-1402.
    • (2014) Blood , vol.123 , pp. 1393-1402
    • Naik, M.U.1    Caplan, J.L.2    Naik, U.P.3
  • 45
    • 0029128907 scopus 로고
    • Mechanisms of platelet activation by a stimulatory antibody: Cross-linking of a novel platelet receptor for monoclonal antibody F11 with the Fc gamma RII receptor
    • Naik U P, Ehrlich YH, Kornecki E (1995). Mechanisms of platelet activation by a stimulatory antibody: cross-linking of a novel platelet receptor for monoclonal antibody F11 with the Fc gamma RII receptor. Biochem J 310, 155-162.
    • (1995) Biochem J , vol.310 , pp. 155-162
    • Naik, U.P.1    Ehrlich, Y.H.2    Kornecki, E.3
  • 46
    • 0035114187 scopus 로고    scopus 로고
    • Characterization and chromosomal localization of JAM-1, a platelet receptor for a stimulatory monoclonal antibody
    • Naik U P, Naik MU, Eckfeld K, Martin-DeLeon P, Spychala J (2001). Characterization and chromosomal localization of JAM-1, a platelet receptor for a stimulatory monoclonal antibody. J Cell Sci 114, 539-547.
    • (2001) J Cell Sci , vol.114 , pp. 539-547
    • Naik, U.P.1    Naik, M.U.2    Eckfeld, K.3    Martin-DeLeon, P.4    Spychala, J.5
  • 47
    • 42049113615 scopus 로고    scopus 로고
    • Attenuation of junctional adhesion molecule-A is a contributing factor for breast cancer cell invasion
    • Naik MU, Naik TU, Suckow AT, Duncan MK, Naik UP (2008). Attenuation of junctional adhesion molecule-A is a contributing factor for breast cancer cell invasion. Cancer Res 68, 2194-2203.
    • (2008) Cancer Res , vol.68 , pp. 2194-2203
    • Naik, M.U.1    Naik, T.U.2    Suckow, A.T.3    Duncan, M.K.4    Naik, U.P.5
  • 49
    • 2542467721 scopus 로고    scopus 로고
    • Vascular endothelial-cad-herin regulates cytoskeletal tension, cell spreading, and focal adhesions by stimulating RhoA
    • Nelson CM, Pirone DM, Tan JL, Chen CS (2004). Vascular endothelial-cad-herin regulates cytoskeletal tension, cell spreading, and focal adhesions by stimulating RhoA. Mol Biol Cell 15, 2943-2953.
    • (2004) Mol Biol Cell , vol.15 , pp. 2943-2953
    • Nelson, C.M.1    Pirone, D.M.2    Tan, J.L.3    Chen, C.S.4
  • 50
    • 84855538157 scopus 로고    scopus 로고
    • Cyclic stretch induces reorientation of cells in a Src family kinase-And p130Cas-dependent manner
    • Niediek V, Born S, Hampe N, Kirchgessner N, Merkel R, Hoffmann B (2012). Cyclic stretch induces reorientation of cells in a Src family kinase-And p130Cas-dependent manner. Eur J Cell Biol 91, 118-128.
    • (2012) Eur J Cell Biol , vol.91 , pp. 118-128
    • Niediek, V.1    Born, S.2    Hampe, N.3    Kirchgessner, N.4    Merkel, R.5    Hoffmann, B.6
  • 51
    • 0036008013 scopus 로고    scopus 로고
    • JAM-1 is a ligand of the beta(2) integrin LFA-1 involved in transendothelial migration of leukocytes
    • Ostermann G, Weber KS, Zernecke A, Schroder A, Weber C (2002). JAM-1 is a ligand of the beta(2) integrin LFA-1 involved in transendothelial migration of leukocytes. Nat Immunol 3, 151-158.
    • (2002) Nat Immunol , vol.3 , pp. 151-158
    • Ostermann, G.1    Weber, K.S.2    Zernecke, A.3    Schroder, A.4    Weber, C.5
  • 52
    • 84875465330 scopus 로고    scopus 로고
    • Tetraspanin CD9 links junctional adhesion molecule-A to alphavbeta3 integrin to mediate basic fbroblast growth factor-specifc angiogenic signaling
    • Peddibhotla SS, Brinkmann B F, Kummer D, Tuncay H, Nakayama M, Adams RH, Gerke V, Ebnet K (2013). Tetraspanin CD9 links junctional adhesion molecule-A to alphavbeta3 integrin to mediate basic fbroblast growth factor-specifc angiogenic signaling. Mol Biol Cell 24, 933-944.
    • (2013) Mol Biol Cell , vol.24 , pp. 933-944
    • Peddibhotla, S.S.1    Brinkmann, B.F.2    Kummer, D.3    Tuncay, H.4    Nakayama, M.5    Adams, R.H.6    Gerke, V.7    Ebnet, K.8
  • 53
    • 79953762540 scopus 로고    scopus 로고
    • Protein kinase C-Alpha signals P115RhoGEF phosphorylation and RhoA activation in TNF-Alpha-induced mouse brain microvascular endothelial cell barrier dysfunction
    • Peng J, He F, Zhang C, Deng X, Yin F (2011). Protein kinase C-Alpha signals P115RhoGEF phosphorylation and RhoA activation in TNF-Alpha-induced mouse brain microvascular endothelial cell barrier dysfunction. J Neuroinfammation 8, 28.
    • (2011) J Neuroinfammation , vol.8 , pp. 28
    • Peng, J.1    He, F.2    Zhang, C.3    Deng, X.4    Yin, F.5
  • 54
    • 84942986749 scopus 로고    scopus 로고
    • Feedback regulation through myosin II confers robustness on RhoA signalling at E-cadherin junctions
    • Priya R, Gomez GA, Budnar S, Verma S, Cox HL, Hamilton NA, Yap AS (2015). Feedback regulation through myosin II confers robustness on RhoA signalling at E-cadherin junctions. Nat Cell Biol 17, 1282-1293.
    • (2015) Nat Cell Biol , vol.17 , pp. 1282-1293
    • Priya, R.1    Gomez, G.A.2    Budnar, S.3    Verma, S.4    Cox, H.L.5    Hamilton, N.A.6    Yap, A.S.7
  • 56
    • 33745757459 scopus 로고    scopus 로고
    • PKCzeta is required for microtubule-based motility of vesicles containing the ntcp transporter
    • Sarkar S, Bananis E, Nath S, Anwer MS, Wolkoff AW, Murray JW (2006). PKCzeta is required for microtubule-based motility of vesicles containing the ntcp transporter. Traffc 7, 1078-1091.
    • (2006) Traffc , vol.7 , pp. 1078-1091
    • Sarkar, S.1    Bananis, E.2    Nath, S.3    Anwer, M.S.4    Wolkoff, A.W.5    Murray, J.W.6
  • 57
    • 84935414352 scopus 로고    scopus 로고
    • Cell-stiffness-induced mechanosignaling-A key driver of leukocyte transendothelial migration
    • Schaefer A, Hordijk PL (2015). Cell-stiffness-induced mechanosignaling-A key driver of leukocyte transendothelial migration. J Cell Sci 128, 2221-2230.
    • (2015) J Cell Sci , vol.128 , pp. 2221-2230
    • Schaefer, A.1    Hordijk, P.L.2
  • 59
    • 0036644975 scopus 로고    scopus 로고
    • Guanine nucleotide exchange factors for Rho GTPases: Turning on the switch
    • Schmidt A, Hall A (2002). Guanine nucleotide exchange factors for Rho GTPases: turning on the switch. Genes Dev 16, 1587-1609.
    • (2002) Genes Dev , vol.16 , pp. 1587-1609
    • Schmidt, A.1    Hall, A.2
  • 61
    • 84878431342 scopus 로고    scopus 로고
    • Phosphatase: PP2A structural importance, regulation and its aberrant expression in cancer
    • Seshacharyulu P, Pandey P, Datta K, Batra SK (2013). Phosphatase: PP2A structural importance, regulation and its aberrant expression in cancer. Cancer Lett 335, 9-18.
    • (2013) Cancer Lett , vol.335 , pp. 9-18
    • Seshacharyulu, P.1    Pandey, P.2    Datta, K.3    Batra, S.K.4
  • 63
    • 67249109157 scopus 로고    scopus 로고
    • Mechanisms of outside-in signaling at the tight junction by junctional adhesion molecule A
    • Severson EA, Parkos CA (2009). Mechanisms of outside-in signaling at the tight junction by junctional adhesion molecule A. Ann NY Acad Sci 1165, 10-18.
    • (2009) Ann NY Acad Sci , vol.1165 , pp. 10-18
    • Severson, E.A.1    Parkos, C.A.2
  • 64
    • 3543025190 scopus 로고    scopus 로고
    • Signaling pathways of the F11 receptor (F11R; A.k.a. JAM-1, JAM-A) in human platelets: F11R dimerization, phosphorylation and complex formation with the integrin GPIIIa
    • Sobocka MB, Sobocki T, Babinska A, Hartwig JH, Li M, Ehrlich YH, Kornecki E (2004). Signaling pathways of the F11 receptor (F11R; a.k.a. JAM-1, JAM-A) in human platelets: F11R dimerization, phosphorylation and complex formation with the integrin GPIIIa. J Recept Signal Transduct Res 24, 85-105.
    • (2004) J Recept Signal Transduct Res , vol.24 , pp. 85-105
    • Sobocka, M.B.1    Sobocki, T.2    Babinska, A.3    Hartwig, J.H.4    Li, M.5    Ehrlich, Y.H.6    Kornecki, E.7
  • 65
    • 80051641129 scopus 로고    scopus 로고
    • Endothelial cell substrate stiffness infuences neutrophil transmigration via myosin light chain kinase-de-pendent cell contraction
    • Stroka KM, Aranda-Espinoza H (2011). Endothelial cell substrate stiffness infuences neutrophil transmigration via myosin light chain kinase-de-pendent cell contraction. Blood 118, 1632-1640.
    • (2011) Blood , vol.118 , pp. 1632-1640
    • Stroka, K.M.1    Aranda-Espinoza, H.2
  • 66
    • 0037059736 scopus 로고    scopus 로고
    • Stretch-induced retinal vascular endothelial growth factor expression is mediated by phosphatidylinositol 3-kinase and protein kinase C (PKC)-zeta but not by stretch-induced ERK1/2, Akt, Ras, or classical/novel PKC pathways
    • Suzuma I, Suzuma K, Ueki K, Hata Y, Feener E P, King GL, Aiello LP (2002). Stretch-induced retinal vascular endothelial growth factor expression is mediated by phosphatidylinositol 3-kinase and protein kinase C (PKC)-zeta but not by stretch-induced ERK1/2, Akt, Ras, or classical/novel PKC pathways. J Biol Chem 277, 1047-1057.
    • (2002) J Biol Chem , vol.277 , pp. 1047-1057
    • Suzuma, I.1    Suzuma, K.2    Ueki, K.3    Hata, Y.4    Feener, E.P.5    King, G.L.6    Aiello, L.P.7
  • 67
    • 80054794980 scopus 로고    scopus 로고
    • Nitric oxide and protein phosphatase 2A provide novel therapeutic opportunities in ER-negative breast cancer
    • Switzer CH, Glynn SA, Ridnour LA, Cheng RY, Vitek M P, Ambs S, Wink DA (2011). Nitric oxide and protein phosphatase 2A provide novel therapeutic opportunities in ER-negative breast cancer. Trends Pharmacol Sci 32, 644-651.
    • (2011) Trends Pharmacol Sci , vol.32 , pp. 644-651
    • Ch, S.1    Glynn, S.A.2    Ridnour, L.A.3    Cheng, R.Y.4    Vitek, M.P.5    Ambs, S.6    Wink, D.A.7
  • 69
    • 84940426404 scopus 로고    scopus 로고
    • JAM-A regulates cortical dynein localization through Cdc42 to control planar spindle orientation during mitosis
    • Tuncay H, Brinkmann BF, Steinbacher T, Schurmann A, Gerke V, Iden S, Ebnet K (2015). JAM-A regulates cortical dynein localization through Cdc42 to control planar spindle orientation during mitosis. Nat Commun 6, 8128.
    • (2015) Nat Commun , vol.6 , pp. 8128
    • Tuncay, H.1    Brinkmann, B.F.2    Steinbacher, T.3    Schurmann, A.4    Gerke, V.5    Iden, S.6    Ebnet, K.7
  • 70
    • 34548395902 scopus 로고    scopus 로고
    • Src family tyrosine kinases mediate contraction of rat isolated tail arteries in response to a hyposmotic stimulus
    • Wijetunge S, Hughes AD (2007). Src family tyrosine kinases mediate contraction of rat isolated tail arteries in response to a hyposmotic stimulus. J Hypertens 25, 1871-1878.
    • (2007) J Hypertens , vol.25 , pp. 1871-1878
    • Wijetunge, S.1    Hughes, A.D.2
  • 72
    • 67650413623 scopus 로고    scopus 로고
    • Endothelial cell activation leads to neutrophil transmigration as supported by the sequential roles of ICAM-2, JAM-A, and PECAM-1
    • Woodfn A, Voisin MB, Imhof BA, Dejana E, Engelhardt B, Nourshargh S (2009). Endothelial cell activation leads to neutrophil transmigration as supported by the sequential roles of ICAM-2, JAM-A, and PECAM-1. Blood 113, 6246-6257.
    • (2009) Blood , vol.113 , pp. 6246-6257
    • Woodfn, A.1    Voisin, M.B.2    Imhof, B.A.3    Dejana, E.4    Engelhardt, B.5    Nourshargh, S.6
  • 73
    • 84897148913 scopus 로고    scopus 로고
    • Association of PKCzeta expression with clinicopathological characteristics of breast cancer
    • Yin J, Liu Z, Li H, Sun J, Chang X, Liu J, He S, Li B (2014). Association of PKCzeta expression with clinicopathological characteristics of breast cancer. PloS One 9, e90811.
    • (2014) PloS One , vol.9 , pp. e90811
    • Yin, J.1    Liu, Z.2    Li, H.3    Sun, J.4    Chang, X.5    Liu, J.6    He, S.7    Li, B.8
  • 74
    • 34250625176 scopus 로고    scopus 로고
    • Force activates smooth muscle alpha-Actin promoter activity through the Rho signaling pathway
    • Zhao XH, Laschinger C, Arora P, Szaszi K, Kapus A, McCulloch CA (2007). Force activates smooth muscle alpha-Actin promoter activity through the Rho signaling pathway. J Cell Sci 120, 1801-1809.
    • (2007) J Cell Sci , vol.120 , pp. 1801-1809
    • Zhao, X.H.1    Laschinger, C.2    Arora, P.3    Szaszi, K.4    Kapus, A.5    McCulloch, C.A.6


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