-
1
-
-
0026075305
-
Use and specificity of genistein as inhibitor of protein-tyrosine kinases
-
Akiyama, T., and H. Ogawara. 1991. Use and specificity of genistein as inhibitor of protein-tyrosine kinases. Methods Enzymol. 201:362-370.
-
(1991)
Methods Enzymol
, vol.201
, pp. 362-370
-
-
Akiyama, T.1
Ogawara, H.2
-
2
-
-
23244440759
-
PECAM-1 mediates NO-dependent dilation of arterioles to high temporal gradients of shear stress
-
Bagi, Z., J.A. Frangos, J.C. Yeh, C.R. White, G. Kaley, and A. Koller. 2005. PECAM-1 mediates NO-dependent dilation of arterioles to high temporal gradients of shear stress. Arterioscler. Thromb. Vasc. Biol. 25: 1590-1595.
-
(2005)
Arterioscler. Thromb. Vasc. Biol
, vol.25
, pp. 1590-1595
-
-
Bagi, Z.1
Frangos, J.A.2
Yeh, J.C.3
White, C.R.4
Kaley, G.5
Koller, A.6
-
3
-
-
0034458943
-
SU6656, a selective src family kinase inhibitor, used to probe growth factor signaling
-
Blake, R.A., M.A. Broome, X. Liu, J. Wu, M. Gishizky, L. Sun, and S.A. Courtneidge. 2000. SU6656, a selective src family kinase inhibitor, used to probe growth factor signaling. Mol. Cell. Biol. 20:9018-9027.
-
(2000)
Mol. Cell. Biol
, vol.20
, pp. 9018-9027
-
-
Blake, R.A.1
Broome, M.A.2
Liu, X.3
Wu, J.4
Gishizky, M.5
Sun, L.6
Courtneidge, S.A.7
-
4
-
-
0032547053
-
Regulation of mouse PECAM-1 tyrosine phosphorylation by the Src and Csk families of protein-tyrosine kinases
-
Cao, M.Y., M. Huber, N. Beauchemin, J. Famiglietti, S.M. Albelda, and A. Veillette. 1998. Regulation of mouse PECAM-1 tyrosine phosphorylation by the Src and Csk families of protein-tyrosine kinases. J. Biol. Chem. 273:15765-15772.
-
(1998)
J. Biol. Chem
, vol.273
, pp. 15765-15772
-
-
Cao, M.Y.1
Huber, M.2
Beauchemin, N.3
Famiglietti, J.4
Albelda, S.M.5
Veillette, A.6
-
5
-
-
0037069931
-
Coordinating Etk/Bmx activation and VEGF upregulation to promote cell survival and proliferation
-
Chau, C.H., K.Y. Chen, H.T. Deng, K.J. Kim, K. Hosoya, T. Terasaki, H.M. Shih, and D.K. Ann. 2002. Coordinating Etk/Bmx activation and VEGF upregulation to promote cell survival and proliferation. Oncogene. 21:8817-8829.
-
(2002)
Oncogene
, vol.21
, pp. 8817-8829
-
-
Chau, C.H.1
Chen, K.Y.2
Deng, H.T.3
Kim, K.J.4
Hosoya, K.5
Terasaki, T.6
Shih, H.M.7
Ann, D.K.8
-
6
-
-
1842535477
-
Endothelial cell-cell adhesion and mechanosignal transduction
-
Chiu, Y.J., K. Kusano, T.N. Thomas, and K. Fujiwara. 2004. Endothelial cell-cell adhesion and mechanosignal transduction. Endothelium. 11:59-73.
-
(2004)
Endothelium
, vol.11
, pp. 59-73
-
-
Chiu, Y.J.1
Kusano, K.2
Thomas, T.N.3
Fujiwara, K.4
-
7
-
-
0034282684
-
Collagen, convulxin, and thrombin stimulate aggregation- independent tyrosine phosphorylation of CD31 in platelets. Evidence for the involvement of Src family kinases
-
Cicmil, M., J.M. Thomas, T. Sage, F.A. Barry, M. Leduc, C. Bon, and J.M. Gibbins. 2000. Collagen, convulxin, and thrombin stimulate aggregation- independent tyrosine phosphorylation of CD31 in platelets. Evidence for the involvement of Src family kinases. J. Biol. Chem. 275:27339-27347.
-
(2000)
J. Biol. Chem
, vol.275
, pp. 27339-27347
-
-
Cicmil, M.1
Thomas, J.M.2
Sage, T.3
Barry, F.A.4
Leduc, M.5
Bon, C.6
Gibbins, J.M.7
-
8
-
-
13644252212
-
SRC family kinases in cell volume regulation
-
Cohen, D.M. 2005. SRC family kinases in cell volume regulation. Am. J. Physiol. Cell Physiol. 288:C483-C493.
-
(2005)
Am. J. Physiol. Cell Physiol
, vol.288
-
-
Cohen, D.M.1
-
9
-
-
4644240387
-
Prediction of resistance to small molecule FLT3 inhibitors: Implications for molecularly targeted therapy of acute leukemia
-
Cools, J., N. Mentens, P. Furet, D. Fabbro, J.J. Clark, J.D. Griffin, P. Marynen, and D.G. Gilliland. 2004. Prediction of resistance to small molecule FLT3 inhibitors: implications for molecularly targeted therapy of acute leukemia. Cancer Res. 64:6385-6389.
-
(2004)
Cancer Res
, vol.64
, pp. 6385-6389
-
-
Cools, J.1
Mentens, N.2
Furet, P.3
Fabbro, D.4
Clark, J.J.5
Griffin, J.D.6
Marynen, P.7
Gilliland, D.G.8
-
10
-
-
0029072762
-
Flow-mediated endothelial mechanotransduction
-
Davies, P.F. 1995. Flow-mediated endothelial mechanotransduction. Physiol. Rev. 75:519-560.
-
(1995)
Physiol. Rev
, vol.75
, pp. 519-560
-
-
Davies, P.F.1
-
11
-
-
0037423813
-
Spatial microstimuli in endothelial mechanosignaling
-
Davies, P.F., J. Zilberberg, and B.P. H elmke. 2003. Spatial microstimuli in endothelial mechanosignaling. Circ. Res. 92:359-370.
-
(2003)
Circ. Res
, vol.92
, pp. 359-370
-
-
Davies, P.F.1
Zilberberg, J.2
elmke, B.P.H.3
-
12
-
-
18644368173
-
Synthesis and initial SAR studies of 3,6-disubstituted pyrazolo[ 1,5-a]pyrimidines: A new class of KDR kinase inhibitors
-
Fraley, M.E., W.F. Hoffman, R.S. Rubino, R.W. Hungate, A.J. Tebben, R.Z. Rutledge, R.C. McFall, W.R. Huckle, R.L. Kendall, K.E. Coll, and K.A. Thomas. 2002. Synthesis and initial SAR studies of 3,6-disubstituted pyrazolo[ 1,5-a]pyrimidines: a new class of KDR kinase inhibitors. Bioorg. Med. Chem. Lett. 12:2767-2770.
-
(2002)
Bioorg. Med. Chem. Lett
, vol.12
, pp. 2767-2770
-
-
Fraley, M.E.1
Hoffman, W.F.2
Rubino, R.S.3
Hungate, R.W.4
Tebben, A.J.5
Rutledge, R.Z.6
McFall, R.C.7
Huckle, W.R.8
Kendall, R.L.9
Coll, K.E.10
Thomas, K.A.11
-
13
-
-
24644497547
-
The Src family kinase c-Yes is required for maturation of West Nile virus particles
-
Hirsch, A.J., G.R. Medigeshi, H.L. Meyers, V. DeFilippis, K. Fruh, T. Briese, W.I. Lipkin, and J.A. Nelson. 2005. The Src family kinase c-Yes is required for maturation of West Nile virus particles. J. Virol. 79:11943-11951.
-
(2005)
J. Virol
, vol.79
, pp. 11943-11951
-
-
Hirsch, A.J.1
Medigeshi, G.R.2
Meyers, H.L.3
DeFilippis, V.4
Fruh, K.5
Briese, T.6
Lipkin, W.I.7
Nelson, J.A.8
-
14
-
-
0030936012
-
The protein-tyrosine phosphatase SHP-2 binds platelet/endothelial cell adhesion molecule-1 (PECAM-1) and forms a distinct signaling complex during platelet aggregation. Evidence for a mechanistic link between PECAM-1- and integrin-mediated cellular signaling
-
Jackson, D.E., C.M. Ward, R. Wang, and P.J. Newman. 1997. The protein-tyrosine phosphatase SHP-2 binds platelet/endothelial cell adhesion molecule-1 (PECAM-1) and forms a distinct signaling complex during platelet aggregation. Evidence for a mechanistic link between PECAM-1- and integrin-mediated cellular signaling. J. Biol. Chem. 272:6986-6993.
-
(1997)
J. Biol. Chem
, vol.272
, pp. 6986-6993
-
-
Jackson, D.E.1
Ward, C.M.2
Wang, R.3
Newman, P.J.4
-
15
-
-
0034644776
-
Cell volume-dependent phosphorylation of proteins of the cortical cytoskeleton and cell-cell contact sites. The role of Fyn and FER kinases
-
Kapus, A., C. Di Ciano, J. Sun, X. Zhan, L. Kim, T.W. Wong, and O.D. Rotstein. 2000. Cell volume-dependent phosphorylation of proteins of the cortical cytoskeleton and cell-cell contact sites. The role of Fyn and FER kinases. J. Biol. Chem. 275:32289-32298.
-
(2000)
J. Biol. Chem
, vol.275
, pp. 32289-32298
-
-
Kapus, A.1
Di Ciano, C.2
Sun, J.3
Zhan, X.4
Kim, L.5
Wong, T.W.6
Rotstein, O.D.7
-
16
-
-
0141632825
-
Identification of Fer tyrosine kinase localized on microtubules as a platelet endothelial cell adhesion molecule-1 phosphorylating kinase in vascular endothelial cells
-
Kogata, N., M. Masuda, Y. Kamioka, A. Yamagishi, A. Endo, M. Okada, and N. Mochizuki. 2003. Identification of Fer tyrosine kinase localized on microtubules as a platelet endothelial cell adhesion molecule-1 phosphorylating kinase in vascular endothelial cells. Mol. Biol. Cell. 14:3553-3564.
-
(2003)
Mol. Biol. Cell
, vol.14
, pp. 3553-3564
-
-
Kogata, N.1
Masuda, M.2
Kamioka, Y.3
Yamagishi, A.4
Endo, A.5
Okada, M.6
Mochizuki, N.7
-
17
-
-
23444452042
-
Molecular basis of the effects of shear stress on vascular endothelial cells
-
Li, Y.S., J.H. Haga, and S. Chien. 2005. Molecular basis of the effects of shear stress on vascular endothelial cells. J. Biomech. 38:1949-1971.
-
(2005)
J. Biomech
, vol.38
, pp. 1949-1971
-
-
Li, Y.S.1
Haga, J.H.2
Chien, S.3
-
19
-
-
0030923190
-
Platelet endothelial cell adhesion molecule-1 is phosphorylatable by c-Src, binds Src-Src homology 2 domain, and exhibits immunoreceptor tyrosine-based activation motif-like properties
-
Lu, T.T., M. Barreuther, S. Davis, and J.A. Madri. 1997. Platelet endothelial cell adhesion molecule-1 is phosphorylatable by c-Src, binds Src-Src homology 2 domain, and exhibits immunoreceptor tyrosine-based activation motif-like properties. J. Biol. Chem. 272:14442-14446.
-
(1997)
J. Biol. Chem
, vol.272
, pp. 14442-14446
-
-
Lu, T.T.1
Barreuther, M.2
Davis, S.3
Madri, J.A.4
-
20
-
-
0033515450
-
-
Mahajan, S., S. Ghosh, E.A. Sudbeck, Y. Zheng, S. Downs, M. Hupke, and F.M. Uckun. 1999. Rational design and synthesis of a novel anti-leukemic agent targeting Bruton's tyrosine kinase (BTK), LFM-A13. J. Biol. Chem. 274:9587-9599 (alpha-cyano-beta-hydroxy-beta-methyl-N-(2, 5-dibromophenyl) propenamide).
-
Mahajan, S., S. Ghosh, E.A. Sudbeck, Y. Zheng, S. Downs, M. Hupke, and F.M. Uckun. 1999. Rational design and synthesis of a novel anti-leukemic agent targeting Bruton's tyrosine kinase (BTK), LFM-A13. J. Biol. Chem. 274:9587-9599 (alpha-cyano-beta-hydroxy-beta-methyl-N-(2, 5-dibromophenyl) propenamide).
-
-
-
-
21
-
-
0031587031
-
Platelet endothelial cell adhesion molecule-1 is a major SH-PTP2 binding protein in vascular endothelial cells
-
Masuda, M., M. Osawa, H. Shigematsu, N. Harada, and K. Fujiwara. 1997. Platelet endothelial cell adhesion molecule-1 is a major SH-PTP2 binding protein in vascular endothelial cells. FEBS Lett. 408:331-336.
-
(1997)
FEBS Lett
, vol.408
, pp. 331-336
-
-
Masuda, M.1
Osawa, M.2
Shigematsu, H.3
Harada, N.4
Fujiwara, K.5
-
22
-
-
0028136280
-
Expression of catalytically inactive Syp phosphatase in 3T3 cells blocks stimulation of mitogen-activated protein kinase by insulin
-
Milarski, K.L., and A.R. Saltiel. 1994. Expression of catalytically inactive Syp phosphatase in 3T3 cells blocks stimulation of mitogen-activated protein kinase by insulin. J. Biol. Chem. 269:21239-21243.
-
(1994)
J. Biol. Chem
, vol.269
, pp. 21239-21243
-
-
Milarski, K.L.1
Saltiel, A.R.2
-
23
-
-
0035871812
-
Inhibition of antigen-receptor signaling by platelet endothelial cell adhesion molecule-1 (CD31) requires functional ITIMs, SHP-2, and p56(lck)
-
Newman, D.K., C. Hamilton, and P.J. Newman. 2001. Inhibition of antigen-receptor signaling by platelet endothelial cell adhesion molecule-1 (CD31) requires functional ITIMs, SHP-2, and p56(lck). Blood. 97:2351-2357.
-
(2001)
Blood
, vol.97
, pp. 2351-2357
-
-
Newman, D.K.1
Hamilton, C.2
Newman, P.J.3
-
24
-
-
0035980217
-
Wheat germ agglutinin-induced platelet activation via platelet endothelial cell adhesion molecule-1: Involvement of rapid phospholipase C gamma 2 activation by Src family kinases
-
Ohmori, T., Y. Yatomi, Y. Wu, M. Osada, K. Satoh, and Y. Ozaki. 2001. Wheat germ agglutinin-induced platelet activation via platelet endothelial cell adhesion molecule-1: involvement of rapid phospholipase C gamma 2 activation by Src family kinases. Biochemistry. 40:12992-13001.
-
(2001)
Biochemistry
, vol.40
, pp. 12992-13001
-
-
Ohmori, T.1
Yatomi, Y.2
Wu, Y.3
Osada, M.4
Satoh, K.5
Ozaki, Y.6
-
25
-
-
29744458411
-
Mechanisms of mechanotransduction
-
Orr, A.W., B.P. Helmke, B.R. Blackman, and M.A. Schwartz. 2006. Mechanisms of mechanotransduction. Dev. Cell. 10:11-20.
-
(2006)
Dev. Cell
, vol.10
, pp. 11-20
-
-
Orr, A.W.1
Helmke, B.P.2
Blackman, B.R.3
Schwartz, M.A.4
-
26
-
-
0030933717
-
Tyrosine phosphorylation of platelet endothelial cell adhesion molecule-1 (PECAM-1, CD31) in mechanically stimulated vascular endothelial cells
-
Osawa, M., M. Masuda, N. Harada, R.B. Lopes, and K. Fujiwara. 1997. Tyrosine phosphorylation of platelet endothelial cell adhesion molecule-1 (PECAM-1, CD31) in mechanically stimulated vascular endothelial cells. Eur. J. Cell Biol. 72:229-237.
-
(1997)
Eur. J. Cell Biol
, vol.72
, pp. 229-237
-
-
Osawa, M.1
Masuda, M.2
Harada, N.3
Lopes, R.B.4
Fujiwara, K.5
-
27
-
-
0037135988
-
Evidence for a role of platelet endothelial cell adhesion molecule-1 in endothelial cell mechanosignal transduction: Is it a mechanoresponsive molecule?
-
Osawa, M., M. Masuda, K. Kusano, and K. Fujiwara. 2002. Evidence for a role of platelet endothelial cell adhesion molecule-1 in endothelial cell mechanosignal transduction: is it a mechanoresponsive molecule? J. Cell Biol. 158:773-785.
-
(2002)
J. Cell Biol
, vol.158
, pp. 773-785
-
-
Osawa, M.1
Masuda, M.2
Kusano, K.3
Fujiwara, K.4
-
28
-
-
0038364117
-
Fluid shear stress and the vascular endothelium: For better and for worse
-
Resnick, N., H. Yahav, A. Shay-Salit, M. Shushy, S. Schubert, L.C. Zilberman, and E. Wofovitz. 2003. Fluid shear stress and the vascular endothelium: for better and for worse. Prog. Biophys. Mol. Biol. 81:177-199.
-
(2003)
Prog. Biophys. Mol. Biol
, vol.81
, pp. 177-199
-
-
Resnick, N.1
Yahav, H.2
Shay-Salit, A.3
Shushy, M.4
Schubert, S.5
Zilberman, L.C.6
Wofovitz, E.7
-
29
-
-
0037128202
-
Force transduction by Triton cytoskeletons
-
Sawada, Y., and M.P. Sheetz. 2002. Force transduction by Triton cytoskeletons. J. Cell Biol. 156:609-615.
-
(2002)
J. Cell Biol
, vol.156
, pp. 609-615
-
-
Sawada, Y.1
Sheetz, M.P.2
-
30
-
-
33751335857
-
Force sensing by mechanical extension of the Src family kinase substrate p130Cas
-
Sawada, Y., M. Tamada, B.J. Dubin-Thaler, O. Cherniavskaya, R. Sakai, S. Tanaka, and M.P. Sheetz. 2006. Force sensing by mechanical extension of the Src family kinase substrate p130Cas. Cell. 127:1015-1026.
-
(2006)
Cell
, vol.127
, pp. 1015-1026
-
-
Sawada, Y.1
Tamada, M.2
Dubin-Thaler, B.J.3
Cherniavskaya, O.4
Sakai, R.5
Tanaka, S.6
Sheetz, M.P.7
-
31
-
-
33846935230
-
Down-regulation of ERK but not MEK phosphorylation in cultured endothelial cells by repeated changes in cyclic stretch
-
Shi, F., Y.J. Chiu, Y. Cho, T.A. Bullard, M. Sokabe, and K. Fujiwara. 2007. Down-regulation of ERK but not MEK phosphorylation in cultured endothelial cells by repeated changes in cyclic stretch. Cardiovasc. Res. 73:813-822.
-
(2007)
Cardiovasc. Res
, vol.73
, pp. 813-822
-
-
Shi, F.1
Chiu, Y.J.2
Cho, Y.3
Bullard, T.A.4
Sokabe, M.5
Fujiwara, K.6
-
32
-
-
23844499088
-
Flow activates ERK1/2 and endothelial nitric oxide synthase via a pathway involving PECAM1, SHP2, and Tie2
-
Tai, L.K., Q. Zheng, S. Pan, Z.G. Jin, and B.C. Berk. 2005. Flow activates ERK1/2 and endothelial nitric oxide synthase via a pathway involving PECAM1, SHP2, and Tie2. J. Biol. Chem. 280:29620-29624.
-
(2005)
J. Biol. Chem
, vol.280
, pp. 29620-29624
-
-
Tai, L.K.1
Zheng, Q.2
Pan, S.3
Jin, Z.G.4
Berk, B.C.5
-
33
-
-
7744232293
-
Activation of a signaling cascade by cytoskeleton stretch
-
Tamada, M., M.P. Sheetz, and Y. Sawada. 2004. Activation of a signaling cascade by cytoskeleton stretch. Dev. Cell. 7:709-718.
-
(2004)
Dev. Cell
, vol.7
, pp. 709-718
-
-
Tamada, M.1
Sheetz, M.P.2
Sawada, Y.3
-
34
-
-
25144510997
-
A mechanosensory complex that mediates the endothelial cell response to fluid shear stress
-
Tzima, E., M. Irani-Tehrani, W.B. Kiosses, E. Dejana, D.A. Schultz, B. Engelhardt, G. Cao, H. DeLisser, and M.A. Schwartz. 2005. A mechanosensory complex that mediates the endothelial cell response to fluid shear stress. Nature. 437:426-431.
-
(2005)
Nature
, vol.437
, pp. 426-431
-
-
Tzima, E.1
Irani-Tehrani, M.2
Kiosses, W.B.3
Dejana, E.4
Schultz, D.A.5
Engelhardt, B.6
Cao, G.7
DeLisser, H.8
Schwartz, M.A.9
-
35
-
-
17844388845
-
Visualizing the mechanical activation of Src
-
Wang, Y., E.L. Botvinick, Y. Zhao, M.W. Berns, S. Usami, R.Y. T sien, and S. Chien. 2005. Visualizing the mechanical activation of Src. Nature. 434:1040-1045.
-
(2005)
Nature
, vol.434
, pp. 1040-1045
-
-
Wang, Y.1
Botvinick, E.L.2
Zhao, Y.3
Berns, M.W.4
Usami, S.5
sien, R.Y.T.6
Chien, S.7
-
36
-
-
33644595058
-
Src, Fyn and Yes play differential roles in VEGF-mediated endothelial cell events
-
Werdich, X.Q., and J.S. Penn. 2005. Src, Fyn and Yes play differential roles in VEGF-mediated endothelial cell events. Angiogenesis. 8:315-326.
-
(2005)
Angiogenesis
, vol.8
, pp. 315-326
-
-
Werdich, X.Q.1
Penn, J.S.2
-
37
-
-
36348941771
-
PECAM-1: A multi-functional molecule in inflammation and vascular biology
-
Woodfin, A., M.B. Voisin, and S. Nourshargh. 2007. PECAM-1: a multi-functional molecule in inflammation and vascular biology. Arterioscler. Thromb. Vasc. Biol. 27:2514-2523.
-
(2007)
Arterioscler. Thromb. Vasc. Biol
, vol.27
, pp. 2514-2523
-
-
Woodfin, A.1
Voisin, M.B.2
Nourshargh, S.3
|