Heterogeneity of endothelial junctions is reflected by differential expression and specific subcellular localization of the three JAM family members

Blood

Volumn 98, Issue 13, 2001, Pages 3699-3707

  Aurrand Lions, Michel ^a,b   Johnson Leger, Caroline ^a,b   Wong, Cindy ^a,b   Du Pasquier, Louis ^a,b   Imhof, Beat A ^a,b  

^a UNIVERSITY OF GENEVA MEDICAL SCHOOL   (Switzerland)

^b BASEL INSTITUTE FOR IMMUNOLOGY   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMAL CELL; ANTIBODY SPECIFICITY; ARTICLE; BLOOD BRAIN BARRIER; BLOOD VESSEL WALL; CELLULAR DISTRIBUTION; ENDOTHELIUM CELL; GENE DISRUPTION; GENETIC HETEROGENEITY; LEUKOCYTE MIGRATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FAMILY; TISSUE SPECIFICITY; VASCULAR ENDOTHELIUM;

EID: 0035895050     PISSN: 00064971     EISSN: None     Source Type: Journal    
DOI: 10.1182/blood.V98.13.3699     Document Type: Article

References (55)

1. Girard JP, Springer TA. High endothelial venules (HEV): specialized endothelium for lymphocyte migration. Immunol Today. 1995;16:449-457.
2. Picker LJ, Butcher EC. Physiological and molecular mechanisms of lymphocyte homing. Annu Rev Immunol. 1992;10:561-591.
3. Springer TA. Traffic signals for lymphocyte recirculation and leukocyte emigration: the multistep paradigm. Cell. 1994;76:301-314.
4. Bevilacqua M, Butcher E, Furie B, et al. Selectins: a family of adhesion receptors. Cell. 1991;67:233.
5. Butcher EC. Leukocyte-endothelial cell recognition: three (or more) steps to specificity and diversity. Cell. 1991;67:1033-1036.
6. Feng D, Nagy JA, Pyne K, Dvorak HF, Dvorak AM. Neutrophils emigrate from venules by a transendothelial cell pathway in response to FMLP. J Exp Med. 1998;187:903-915.
7. Pawlowski NA, Kaplan G, Abraham E, Cohn ZA. The selective binding and transmigration of monocytes through the junctional complexes of human endothelium. J Exp Med. 1988;168:1865-1882.
8. Allport JR, Ding H, Collins T, Gerritsen ME, Luscinskas FW. Endothelial-dependent mechanisms regulate leukocyte transmigration: a process involving the proteasome and disruption of the vascular endothelial-cadherin complex at endothelial cell-to-cell junctions. J Exp Med. 1997;186:517-527.
9. Allport JR, Muller WA, Luscinskas FW. Monocytes induce reversible focal changes in vascular endothelial cadherin complex during transendothelial migration under flow. J Cell Biol. 2000;148:203-216.
10. Moll T, Dejana E, Vestweber D. In vitro degradation of endothelial catenins by a neutrophil protease. J Cell Biol. 1998;140:403-407.
11. Burns AR, Walker DC, Brown ES, et al. Neutrophil transendothelial migration is independent of tight junctions and occurs preferentially at tricellular corners. J Immunol. 1997;159:2893-2903.
12. Vestweber D. Molecular mechanisms that control endothelial cell contacts. J Pathol. 2000;190:281-291.
13. Johnson-Leger C, Aurrand-Lions M, Imhof BA. The parting of the endothelium: miracle, or simply a junctional affair? J Cell Sci. 2000;113:921-933.
14. Simionescu M, Simionescu N, Palade GE. Segmental differentiations of cell junctions in the vascular endothelium: the microvasculature. J Cell Biol. 1975;67:863-885.
15. Karnovsky MJ. The ultrastructural basis of capillary permeability studied with peroxidase as a tracer. J Cell Biol. 1967;35:213-236.
16. Furuse M, Hirase T, Itoh M, Nagafuchi A, Yonemura S, Tsukita S. Occludin: a novel integral membrane protein localizing at tight junctions [see comments]. J Cell Biol. 1993;123:1777-1788.
17. Furuse M, Fujita K, Hiiragi T, Fujimoto K, Tsukita S. Claudin-1 and -2: novel integral membrane proteins localizing at tight junctions with no sequence similarity to occludin. J Cell Biol. 1998;141:1539-1550.
18. Takeichi M. The cadherins: cell-cell adhesion molecules controlling animal morphogenesis. Development. 1988;102:639-655.
19. Goodenough DA, Goliger JA, Paul DL. Connexins, connexons, and intercellular communication. Annu Rev Biochem. 1996;65:475-502.
20. Lampugnani MG, Corada M, Caveda L, et al. The molecular organization of endothelial cell to cell junctions: differential association of plakoglobin, beta-catenin, and alpha-catenin with vascular endothelial cadherin (VE-cadherin). J Cell Biol. 1995;129:203-217.
21. Morita K, Sasaki H, Furuse M, Tsukita S. Endothelial claudin: claudin-5/TMVCF constitutes tight junction strands in endothelial cells. J Cell Biol. 1999;147:185-194.
22. Corada M, Mariotti M, Thurston G, et al. Vascular endothelial-cadherin is an important determinant of microvascular integrity in vivo. Proc Natl Acad Sci U S A. 1999;96:9815-9820.
23. Liebner S, Fischmann A, Rascher G, et al. Claudin-1 and claudin-5 expression and tight junction morphology are altered in blood vessels of human glioblastoma multiforme. Acta Neuropathol (Berl). 2000;100:323-331.
24. Hirase T, Staddon JM, Saitou M, et al. Occludin as a possible determinant of tight junction permeability in endothelial cells. J Cell Sci. 1997;110:1603-1613.
25. Dejana E, Corada M, Lampugnani MG. Endothelial cell-to-cell junctions. FASEB J. 1995;9:910-918.
26. Aurrand-Lions MA, Duncan L, Ballestrem C, Imhof BA. JAM-2, a novel immunoglobulin superfamily molecule, expressed by endothelial and lymphatic cells. J Biol Chem. 2000;276:2733-2741.
27. Martin-Padura I, Lostaglio S, Schneemann M, et al. Junctional adhesion molecule, a novel member of the immunoglobulin superfamily that distributes at intercellular junctions and modulates monocyte transmigration. J Cell Biol. 1998;142:117-127.
28. Del Maschio A, De Luigi A, Martin-Padura I, et al. Leukocyte recruitment in the cerebrospinal fluid of mice with experimental meningitis is inhibited by an antibody to junctional adhesion molecule (JAM). J Exp Med. 1999;190:11351-1356.
29. Bazzoni G, Martinez-Estrada OM, Orsenigo F, Cordenonsi M, Citi S, Dejana E. Interaction of junctional adhesion molecule with the tight junction components ZO-1, cingulin, and occludin. J Biol Chem. 2000;275:20520-20526.
30. Ebnet K, Schulz CU, Meyer Zu Brickwedde MK, Pendl GG, Vestweber D. Junctional adhesion molecule interacts with the PDZ domain-containing proteins AF-6 and ZO-1. J Biol Chem. 2000;275:27979-27988.
31. Lechner F, Sahrbacher U, Suter T, et al. Antibodies to the junctional adhesion molecule cause disruption of endothelial cells and do not prevent leukocyte influx into the meninges after viral or bacterial infection. J Infect Dis. 2000;182:978-982.
32. Palmeri D, van Zante A, Huang CC, Hemmerich S, Rosen SD. Vascular endothelial junction-associated molecule, a novel member of the immunoglobulin superfamily, is localized to intercellular boundaries of endothelial cells. J Biol Chem. 2000;275:19139-19145.
33. Cunningham SA, Arrate MP, Rodriguez JM, et al. A novel protein with homology to the junctional adhesion molecule: characterization of leukocyte interactions. J Biol Chem. 2000;275:34750-34756.
34. Liu Y, Nusrat A, Schnell FJ, et al. Human junction adhesion molecule regulates tight junction resealing in epithelia. J Cell Sci. 2000;113:2363-2374.
35. Du Pasquier L, Courtet M, Chretien I. Duplication and MHC linkage of the CTX family of genes in Xenopus and in mammals. Eur J Immunol. 1999;29:1729-1739.
36. Chretien l, Marcuz A, Courtet M, at al. CTX, a Xenopus thymocyte receptor, defines a molecular family conserved throughout vertebrates. Eur J Immunol. 1998;28:4094-4104.
37. Williams RL, Risau W, Zerwes HG, Drexler H, Aguzzi A, Wagner EF. Endothelioma cells expressing the polyoma middle T oncogene induce hemangiomas by host cell recruitment. Cell. 1989;57:1053-1063.
38. Harder R, Uhlig H, Kashan A, et al. Dissection of murine lymphocyte-endothelial cell interaction mechanisms by SV-40-transformed mouse endothelial cell lines: novel mechanisms mediating basal binding, and alpha 4-integrin-dependent cytokine-induced adhesion. Exp Cell Res. 1991;197:259-267.
39. Berg EL, Mullowney AT, Andrew DP, Goldberg JE, Butcher EC. Complexity and differential expression of carbohydrate epitopes associated with L-selectin recognition of high endothelial venules. Am J Pathol. 1998;152:469-477.
40. Piali L, Hammel P, Uherek C, et al. CD31/PECAM-1 is a ligand for alpha v beta 3 integrin involved in adhesion of leukocytes to endothelium. J Cell Biol. 1995;130:451-460.
41. Malergue F, Galland F, Martin F, Mansuelle P, Aurrand-Lions M, Naquet P. A novel immunoglobulin superfamily junctional molecule expressed by antigen presenting cells, endothelial cells and platelets. Mol Immunol. 1998;35:1111-1119.
42. Stevenson BR, Siliciano JD, Mooseker MS, Goodenough DA. Identification of ZO-1: a high molecular weight polypeptide associated with the tight junction (zonula occludens) in a variety of epithelia. J Cell Biol. 1986;103:755-766.
43. Wiedle G, Johnson-Leger C, Imhof BA. A chimeric cell adhesion molecule mediates homing of lymphocytes to vascularized tumors. Cancer Res. 1999;59:5255-5263.
44. Naik UP, Naik MU, Eckfeld K, Martin-DeLeon P, Spychala J. Characterization and chromosomal localization of JAM-1, a platelet receptor for a stimulatory monoclonal antibody. J Cell Sci. 2001;114:539-547.
45. Leahy DJ. Implications of atomic-resolution structures for cell adhesion. Annu Rev Cell Dev Biol. 1997;13:363-393.
46. Bork P, Holm L, Sander C. The immunoglobulin fold: structural classification, sequence patterns and common core. J Mol Biol. 1994;242:309-320.
47. Kasahara M. Genome dynamics of the major histocompatibility complex: insights from genome paralogy. Immunogenetics. 1999;50:134-145.
48. Williams LA, Martin-Padura I, Dejana E, Hogg N, Simmons DL. Identification and characterisation of human junctional adhesion molecule (JAM). Mol Immunol. 1999;36:1175-1188.
49. Liang TW, DeMarco RA, Mrsny R J, et al. Characterization of huJAM: evidence for involvement in cell-cell contact and tight junction regulation. Am J Physiol Cell Physiol. 2000;279:C1733-1743.
50. Rubin LL. Endothelial cells: adhesion and tight junctions. Curr Opin Cell Biol. 1992;4:830-833.
51. Kniesel U, Wolburg H. Tight junctions of the blood-brain barrier. Cell Mol Neurobiol. 2000;20:57-76.
52. Mikata A, Niki R. Permeability of postcapillary venules of the lymph node: an electron microscopic study. Exp Mol Pathol. 1971;14:289-305.
53. van Deurs B, Ropke C, Westergaard E. Permeability properties of the postcapillary high-endothelial venules in lymph nodes of the mouse. Lab Invest. 1975;32:201-208.
54. Schmelz M, Franke WW. Complexus adhaerentes, a new group of desmoplakin-containing junctions in endothelial cells: the syndesmos connecting retothelial cells of lymph nodes. Eur J Cell Biol. 1993;61:274-289.
55. Schnittler HJ. Structural and functional aspects of intercellular junctions in vascular endothelium. Basic Res Cardiol. 1998;93:30-39.