Protein stability, conformational change and binding mechanism of human serum albumin upon binding of embelin and its role in disease control

Journal of Photochemistry and Photobiology B: Biology

Volumn 160, Issue , 2016, Pages 248-259

  Yeggoni, Daniel Pushparaju ^a   Rachamallu, Aparna ^a   Subramanyam, Rajagopal ^a  

^a UNIVERSITY OF HYDERABAD   (India)

Author keywords

Free energy; MicroTOF Q; Molecular docking; Molecular dynamics simulations; Protein conformation; Protein ligand interaction

Indexed keywords

EMBELIN; HUMAN SERUM ALBUMIN; BENZOQUINONE DERIVATIVE; PROTEIN BINDING; SERUM ALBUMIN;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; BINDING AFFINITY; CANCER CONTROL; CANCER INHIBITION; CIRCULAR DICHROISM; COMPLEX FORMATION; CONFORMATIONAL TRANSITION; DOSE RESPONSE; DRUG PROTEIN BINDING; FEMALE; HELA CELL LINE; HUMAN; HUMAN CELL; HUMAN CELL CULTURE; IC50; MOLECULAR DYNAMICS; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN FOLDING; PROTEIN STABILITY; UTERINE CERVIX CANCER; BINDING SITE; CHEMISTRY; DRUG EFFECTS; ELECTROSPRAY MASS SPECTROMETRY; METABOLISM; MOLECULAR DOCKING; PROTEIN TERTIARY STRUCTURE; SPECTROFLUOROMETRY; THERMODYNAMICS; TRANSMISSION ELECTRON MICROSCOPY;

APOPTOSIS; BENZOQUINONES; BINDING SITES; CIRCULAR DICHROISM; HELA CELLS; HUMANS; MICROSCOPY, ELECTRON, TRANSMISSION; MOLECULAR DOCKING SIMULATION; MOLECULAR DYNAMICS SIMULATION; PROTEIN BINDING; PROTEIN STABILITY; PROTEIN STRUCTURE, TERTIARY; SERUM ALBUMIN; SPECTROMETRY, FLUORESCENCE; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION; THERMODYNAMICS;

EID: 84964824807     PISSN: 10111344     EISSN: 18732682     Source Type: Journal    
DOI: 10.1016/j.jphotobiol.2016.04.012     Document Type: Article

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