Cytotoxicity and comparative binding mechanism of piperine with human serum albumin and α-1-acid glycoprotein

Journal of Biomolecular Structure and Dynamics

Volumn 33, Issue 6, 2015, Pages 1336-1351

  Yeggoni, Daniel Pushparaju ^a   Rachamallu, Aparna ^a   Kallubai, Monika ^a   Subramanyam, Rajagopal ^a  

^a UNIVERSITY OF HYDERABAD   (India)

Author keywords

cytotoxicity; drug binding; fluorescence quenching; human serum albumin; molecular dynamics simulation; piperine; 1 acid glycoprotein

Indexed keywords

HUMAN SERUM ALBUMIN; OROSOMUCOID; PIPERINE; 1,3 BENZODIOXOLE DERIVATIVE; ALKALOID; AMIDE; ANTIINFLAMMATORY AGENT; PIPERIDINE DERIVATIVE; PROTEIN BINDING; SERUM ALBUMIN;

ANIMAL CELL; ANTIINFLAMMATORY ACTIVITY; ARTICLE; BINDING AFFINITY; CELL GROWTH; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOTOXICITY; DRUG BINDING SITE; DRUG PROTEIN BINDING; HUMAN; HUMAN CELL; HYDROPHILICITY; HYDROPHOBICITY; MACROPHAGE; MOLECULAR DOCKING; MOLECULAR DYNAMICS; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN SECONDARY STRUCTURE; THERMOSTABILITY; ALGORITHM; ANIMAL; BINDING SITE; CELL LINE; CHEMICAL PHENOMENA; CHEMISTRY; CIRCULAR DICHROISM; DRUG EFFECTS; METABOLISM; PROTEIN CONFORMATION; PROTEIN STABILITY; THEORETICAL MODEL; THERMODYNAMICS;

ALGORITHMS; ALKALOIDS; ANIMALS; ANTI-INFLAMMATORY AGENTS; BENZODIOXOLES; BINDING SITES; CELL LINE; CIRCULAR DICHROISM; HUMANS; HYDROPHOBIC AND HYDROPHILIC INTERACTIONS; MACROPHAGES; MICE; MODELS, THEORETICAL; MOLECULAR DOCKING SIMULATION; MOLECULAR DYNAMICS SIMULATION; OROSOMUCOID; PIPERIDINES; POLYUNSATURATED ALKAMIDES; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN STABILITY; PROTEIN STRUCTURE, SECONDARY; SERUM ALBUMIN; THERMODYNAMICS;

EID: 84925708324     PISSN: 07391102     EISSN: 15380254     Source Type: Journal    
DOI: 10.1080/07391102.2014.947326     Document Type: Article

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