Aryl Hydrocarbon receptor plays protective roles against high fat diet (hfd)-induced hepatic steatosis and the subsequent lipotoxicity via direct transcriptional regulation of socs3 gene expression

Journal of Biological Chemistry

Volumn 291, Issue 13, 2016, Pages 7004-7016

  Wada, Taira ^a   Sunaga, Hiroshi ^a   Miyata, Kazuki ^a   Shirasaki, Haruno ^a   Uchiyama, Yuki ^a   Shimba, Shigeki ^a  

^a NIHON UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

DETOXIFICATION; ENZYME INHIBITION; GENE EXPRESSION; GENES; HYDROCARBONS; MAMMALS; METABOLISM; PATHOLOGY; PHYSIOLOGY; TRANSCRIPTION;

ARYL HYDROCARBON RECEPTOR; BIOCHEMICAL STUDIES; ENERGY METABOLISM; GENE EXPRESSION ANALYSIS; HEPATIC STEATOSIS; PROMOTER ANALYSIS; TRANSCRIPTIONAL REGULATION; TRANSCRIPTIONAL TARGETS;

GENE EXPRESSION REGULATION;

AROMATIC HYDROCARBON RECEPTOR; SUPPRESSOR OF CYTOKINE SIGNALING 3; AHR PROTEIN, MOUSE; BASIC HELIX LOOP HELIX TRANSCRIPTION FACTOR; FAT INTAKE; PROTEIN BINDING; SOCS3 PROTEIN, MOUSE; SUPPRESSOR OF CYTOKINE SIGNALING;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DISEASE SEVERITY; FATTY LIVER; GEL MOBILITY SHIFT ASSAY; GENE EXPRESSION; HEPATITIS; HUMAN; HUMAN CELL; KNOCKOUT MOUSE; LIPID DIET; LIPID METABOLISM; LIPOGENESIS; LIPOTOXICITY; LIVER INJURY; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; PROTECTION; PROTEIN ANALYSIS; PROTEIN FUNCTION; SOCS3 GENE; TRANSCRIPTION REGULATION; ADVERSE EFFECTS; ANIMAL; BINDING SITE; C57BL MOUSE; DEFICIENCY; FAT INTAKE; GENE EXPRESSION REGULATION; GENETIC TRANSCRIPTION; GENETICS; LIVER; METABOLISM; PATHOLOGY; SIGNAL TRANSDUCTION;

ANIMALS; BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTORS; BINDING SITES; DIET, HIGH-FAT; DIETARY FATS; FATTY LIVER; GENE EXPRESSION REGULATION; LIPID METABOLISM; LIVER; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; PROMOTER REGIONS, GENETIC; PROTEIN BINDING; RECEPTORS, ARYL HYDROCARBON; SIGNAL TRANSDUCTION; SUPPRESSOR OF CYTOKINE SIGNALING 3 PROTEIN; SUPPRESSOR OF CYTOKINE SIGNALING PROTEINS; TRANSCRIPTION, GENETIC;

EID: 84964807520     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M115.693655     Document Type: Article

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