Structural modeling of JAK1 mutations in T-cell acute lymphoblastic leukemia reveals a second contact site between pseudokinase and kinase domains

Haematologica

Volumn 101, Issue 5, 2016, Pages e189-e191

  Canté Barrett, Kirsten ^a   Uitdehaag, Joost C M ^b   Meijerink, Jules P P ^a  

^a SOPHIA CHILDREN S HOSPITAL   (Netherlands)

^b Netherlands Translational Research Center BV   (Netherlands)

Author keywords

Activating mutation; JAK1; Structure; T cell acute lymphoblastic leukemia; TYK2

Indexed keywords

INTERLEUKIN 7; INTERLEUKIN 7 RECEPTOR; JANUS KINASE 1; JANUS KINASE 2; JANUS KINASE 3; PROTEIN KINASE TYK2;

ACUTE LYMPHOBLASTIC LEUKEMIA; B LYMPHOCYTE; CELL MATURATION; CHROMOSOME REARRANGEMENT; HUMAN; LETTER; MUTATION; POLYCYTHEMIA; T LYMPHOCYTE; GENETICS;

HUMANS; JANUS KINASE 1; MUTATION; PRECURSOR T-CELL LYMPHOBLASTIC LEUKEMIA-LYMPHOMA;

EID: 84964787419     PISSN: 03906078     EISSN: 15928721     Source Type: Journal    
DOI: 10.3324/haematol.2015.138248     Document Type: Letter

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