-
1
-
-
0037142071
-
Crystal structure of parallel quadruplexes from human telomeric DNA
-
Parkinson, G. N., Lee, M. P. & Neidle, S. Crystal structure of parallel quadruplexes from human telomeric DNA. Nature 417, 876-880 (2002).
-
(2002)
Nature
, vol.417
, pp. 876-880
-
-
Parkinson, G.N.1
Lee, M.P.2
Neidle, S.3
-
2
-
-
20144364292
-
Prevalence of quadruplexes in the human genome
-
Huppert, J. L. & Balasubramanian, S. Prevalence of quadruplexes in the human genome. Nucleic Acids Res. 33, 2908-2916 (2005).
-
(2005)
Nucleic Acids Res.
, vol.33
, pp. 2908-2916
-
-
Huppert, J.L.1
Balasubramanian, S.2
-
3
-
-
20144369806
-
Highly prevalent putative quadruplex sequence motifs in human DNA
-
Todd, A. K., Johnston, M. & Neidle, S. Highly prevalent putative quadruplex sequence motifs in human DNA. Nucleic Acids Res. 33, 2901-2907 (2005).
-
(2005)
Nucleic Acids Res.
, vol.33
, pp. 2901-2907
-
-
Todd, A.K.1
Johnston, M.2
Neidle, S.3
-
4
-
-
84890958553
-
Visualization and selective chemical targeting of RNA G-quadruplex structures in the cytoplasm of human cells
-
Biffi, G., Di Antonio, M., Tannahill, D. & Balasubramanian, S. Visualization and selective chemical targeting of RNA G-quadruplex structures in the cytoplasm of human cells. Nat. Chem. 6, 75-80 (2014).
-
(2014)
Nat. Chem.
, vol.6
, pp. 75-80
-
-
Biffi, G.1
Di Antonio, M.2
Tannahill, D.3
Balasubramanian, S.4
-
5
-
-
84875464903
-
Quantitative visualization of DNA G-quadruplex structures in human cells
-
Biffi, G., Tannahill, D., McCafferty, J. & Balasubramanian, S. Quantitative visualization of DNA G-quadruplex structures in human cells. Nat. Chem. 5, 182-186 (2013).
-
(2013)
Nat. Chem.
, vol.5
, pp. 182-186
-
-
Biffi, G.1
Tannahill, D.2
McCafferty, J.3
Balasubramanian, S.4
-
6
-
-
84877768759
-
G-quadruplex structures are stable and detectable in human genomic DNA
-
Lam, E. Y., Beraldi, D., Tannahill, D. & Balasubramanian, S. G-quadruplex structures are stable and detectable in human genomic DNA. Nat. Commun. 4, 1796 (2013).
-
(2013)
Nat. Commun.
, vol.4
, pp. 1796
-
-
Lam, E.Y.1
Beraldi, D.2
Tannahill, D.3
Balasubramanian, S.4
-
7
-
-
84857163904
-
Small-molecule-induced DNA damage identifies alternative DNA structures in human genes
-
Rodriguez, R. et al. Small-molecule-induced DNA damage identifies alternative DNA structures in human genes. Nat. Chem. Biol. 8, 301-310 (2012).
-
(2012)
Nat. Chem. Biol.
, vol.8
, pp. 301-310
-
-
Rodriguez, R.1
-
8
-
-
79953313413
-
Targeting G-quadruplexes in gene promoters: A novel anticancer strategy?
-
Balasubramanian, S., Hurley, L. H. & Neidle, S. Targeting G-quadruplexes in gene promoters: a novel anticancer strategy? Nat. Rev. Drug Discov. 10, 261-275 (2011).
-
(2011)
Nat. Rev. Drug Discov.
, vol.10
, pp. 261-275
-
-
Balasubramanian, S.1
Hurley, L.H.2
Neidle, S.3
-
9
-
-
81455140677
-
The application of DNA and RNA G-quadruplexes to therapeutic medicines
-
Collie, G. W. & Parkinson, G. N. The application of DNA and RNA G-quadruplexes to therapeutic medicines. Chem. Soc. Rev. 40, 5867-5892 (2011).
-
(2011)
Chem. Soc. Rev.
, vol.40
, pp. 5867-5892
-
-
Collie, G.W.1
Parkinson, G.N.2
-
10
-
-
84890516811
-
Exploring the chemical space of G-quadruplex binders: Discovery of a novel chemotype targeting the human telomeric sequence
-
Di Leva, F. S. et al. Exploring the chemical space of G-quadruplex binders: discovery of a novel chemotype targeting the human telomeric sequence. J. Med. Chem. 56, 9646-9654 (2013).
-
(2013)
J. Med. Chem.
, vol.56
, pp. 9646-9654
-
-
Di Leva, F.S.1
-
11
-
-
84869996732
-
Shooting for selective druglike G-quadruplex binders: Evidence for telomeric DNA damage and tumor cell death
-
Cosconati, S. et al. Shooting for selective druglike G-quadruplex binders: evidence for telomeric DNA damage and tumor cell death. J. Med. Chem. 55, 9785-9792 (2012).
-
(2012)
J. Med. Chem.
, vol.55
, pp. 9785-9792
-
-
Cosconati, S.1
-
12
-
-
84872204067
-
Sequence, stability, and structure of G-quadruplexes and their interactions with drugs
-
Chen, Y. & Yang, D. Sequence, stability, and structure of G-quadruplexes and their interactions with drugs. Curr. Protoc. Nucleic Acid Chem. 50, 17.5.1-17.5.17 (2012).
-
(2012)
Curr. Protoc. Nucleic Acid Chem.
, vol.50
, pp. 1-17
-
-
Chen, Y.1
Yang, D.2
-
13
-
-
84867622361
-
G-quadruplexes in RNA biology
-
Millevoi, S., Moine, H. & Vagner, S. G-quadruplexes in RNA biology. Wiley Interdiscip. Rev. RNA 3, 495-507 (2012).
-
(2012)
Wiley Interdiscip. Rev. RNA
, vol.3
, pp. 495-507
-
-
Millevoi, S.1
Moine, H.2
Vagner, S.3
-
14
-
-
77956539976
-
A crystallographic and modelling study of a human telomeric RNA (TERRA) quadruplex
-
Collie, G. W., Haider, S. M., Neidle, S. & Parkinson, G. N. A crystallographic and modelling study of a human telomeric RNA (TERRA) quadruplex. Nucleic Acids Res. 38, 5569-5580 (2010).
-
(2010)
Nucleic Acids Res.
, vol.38
, pp. 5569-5580
-
-
Collie, G.W.1
Haider, S.M.2
Neidle, S.3
Parkinson, G.N.4
-
15
-
-
79952269800
-
Structural basis of telomeric RNA quadruplex-acridine ligand recognition
-
Collie, G. W., Sparapani, S., Parkinson, G. N. & Neidle, S. Structural basis of telomeric RNA quadruplex-acridine ligand recognition. J. Am. Chem. Soc. 133, 2721-2728 (2011).
-
(2011)
J. Am. Chem. Soc.
, vol.133
, pp. 2721-2728
-
-
Collie, G.W.1
Sparapani, S.2
Parkinson, G.N.3
Neidle, S.4
-
16
-
-
84875896821
-
Circular dichroism of quadruplex structures
-
Randazzo, A., Spada, G. P. & da Silva, M. W. Circular dichroism of quadruplex structures. Top. Curr. Chem. 330, 67-86 (2013).
-
(2013)
Top. Curr. Chem.
, vol.330
, pp. 67-86
-
-
Randazzo, A.1
Spada, G.P.2
Da Silva, M.W.3
-
17
-
-
84949957913
-
Directly lighting up RNA G-quadruplexes from test tubes to living human cells
-
Xu, S. et al. Directly lighting up RNA G-quadruplexes from test tubes to living human cells. Nucleic Acids Res. 43, 9575-9586 (2015).
-
(2015)
Nucleic Acids Res.
, vol.43
, pp. 9575-9586
-
-
Xu, S.1
-
18
-
-
78049308448
-
Protein-induced photophysical changes to the amyloid indicator dye thioflavin T
-
Wolfe, L. S. et al. Protein-induced photophysical changes to the amyloid indicator dye thioflavin T. Proc. Natl. Acad. Sci. USA 107, 16863-16868 (2010).
-
(2010)
Proc. Natl. Acad. Sci. USA
, vol.107
, pp. 16863-16868
-
-
Wolfe, L.S.1
-
19
-
-
84866388266
-
Molecular rotors: What lies behind the high sensitivity of the Thioflavin-T fluorescent marker
-
Amdursky, N., Erez, Y. & Huppert, D. Molecular Rotors: What Lies Behind the High Sensitivity of the Thioflavin-T Fluorescent Marker. Acc. Chem. Res. 45, 1548-1557 (2012).
-
(2012)
Acc. Chem. Res.
, vol.45
, pp. 1548-1557
-
-
Amdursky, N.1
Erez, Y.2
Huppert, D.3
-
20
-
-
84893610214
-
+ sensor
-
+ sensor. Anal. Chem. 86, 1622-1631 (2014).
-
(2014)
Anal. Chem.
, vol.86
, pp. 1622-1631
-
-
Liu, L.1
-
21
-
-
84872100978
-
Thioflavin T as an efficient inducer and selective fluorescent sensor for the human telomeric G-quadruplex DNA
-
Mohanty, J. et al. Thioflavin T as an efficient inducer and selective fluorescent sensor for the human telomeric G-quadruplex DNA. J. Am. Chem. Soc. 135, 367-376 (2013).
-
(2013)
J. Am. Chem. Soc.
, vol.135
, pp. 367-376
-
-
Mohanty, J.1
-
22
-
-
58149175632
-
Thioflavin T as a molecular rotor: Fluorescent properties of thioflavin T in solvents with different viscosity
-
Stsiapura, V. I. et al. Thioflavin T as a molecular rotor: fluorescent properties of thioflavin T in solvents with different viscosity. J. Phys. Chem. B 112, 15893-15902 (2008).
-
(2008)
J. Phys. Chem. B
, vol.112
, pp. 15893-15902
-
-
Stsiapura, V.I.1
-
23
-
-
64849111470
-
Fluorescent sensor for monitoring structural changes of G-quadruplexes and detection of potassium ion
-
Kong, D. M., Ma, Y. E., Guo, J. H., Yang, W. & Shen, H. X. Fluorescent sensor for monitoring structural changes of G-quadruplexes and detection of potassium ion. Anal. Chem. 81, 2678-2684 (2009).
-
(2009)
Anal. Chem.
, vol.81
, pp. 2678-2684
-
-
Kong, D.M.1
Ma, Y.E.2
Guo, J.H.3
Yang, W.4
Shen, H.X.5
-
24
-
-
84857082456
-
Early detection of insulin fibrillation: A fluorescence lifetime assay to probe the pre-fibrillar regime
-
Mohanty, J., Choudhury, S. D., Pal, H. & Bhasikuttan, A. C. Early detection of insulin fibrillation: a fluorescence lifetime assay to probe the pre-fibrillar regime. Chem. Commun. 48, 2403-2405 (2012).
-
(2012)
Chem. Commun.
, vol.48
, pp. 2403-2405
-
-
Mohanty, J.1
Choudhury, S.D.2
Pal, H.3
Bhasikuttan, A.C.4
-
25
-
-
84875800206
-
Bulges in G-quadruplexes: Broadening the definition of G-quadruplex-forming sequences
-
Mukundan, V. T. & Phan, A. T. Bulges in G-quadruplexes: broadening the definition of G-quadruplex-forming sequences. J. Am. Chem. Soc. 135, 5017-5028 (2013).
-
(2013)
J. Am. Chem. Soc.
, vol.135
, pp. 5017-5028
-
-
Mukundan, V.T.1
Phan, A.T.2
-
26
-
-
84905639191
-
Structural basis for activity of highly efficient RNA mimics of green fluorescent protein
-
Warner, K. D. et al. Structural basis for activity of highly efficient RNA mimics of green fluorescent protein. Nat. Struct. Mol. Biol. 21, 658-663 (2014).
-
(2014)
Nat. Struct. Mol. Biol.
, vol.21
, pp. 658-663
-
-
Warner, K.D.1
-
27
-
-
79960959180
-
RNA mimics of green fluorescent protein
-
Paige, J. S., Wu, K. Y. & Jaffrey, S. R. RNA mimics of green fluorescent protein. Science 333, 642-646 (2011).
-
(2011)
Science
, vol.333
, pp. 642-646
-
-
Paige, J.S.1
Wu, K.Y.2
Jaffrey, S.R.3
-
28
-
-
84904731281
-
A G-quadruplex-containing RNA activates fluorescence in a GFP-like fluorophore
-
Huang, H. et al. A G-quadruplex-containing RNA activates fluorescence in a GFP-like fluorophore. Nat. Chem. Biol. 10, 686-691 (2014).
-
(2014)
Nat. Chem. Biol.
, vol.10
, pp. 686-691
-
-
Huang, H.1
-
29
-
-
84919934354
-
G-quadruplex structures contribute to the neuroprotective effects of angiogenin-induced tRNA fragments
-
Ivanov, P. et al. G-quadruplex structures contribute to the neuroprotective effects of angiogenin-induced tRNA fragments. Proc. Natl. Acad. Sci. USA 111, 18201-18206 (2014).
-
(2014)
Proc. Natl. Acad. Sci. USA
, vol.111
, pp. 18201-18206
-
-
Ivanov, P.1
-
30
-
-
84864600748
-
Development of a universal colorimetric indicator for G-Quadruplex structures by the fusion of thiazole orange and isaindigotone skeleton
-
Yan, J. W. et al. Development of a universal colorimetric indicator for G-Quadruplex structures by the fusion of thiazole orange and isaindigotone skeleton. Anal. Chem. 84, 6288-6292 (2012).
-
(2012)
Anal. Chem.
, vol.84
, pp. 6288-6292
-
-
Yan, J.W.1
-
31
-
-
77951780294
-
Viscosity effect on the ultrafast bond twisting dynamics in an amyloid fibril sensor: Thioflavin-T
-
Singh, P. K., Kumbhakar, M., Pal, H. & Nath, S. Viscosity effect on the ultrafast bond twisting dynamics in an amyloid fibril sensor: Thioflavin-T. J. Phys. Chem. B 114, 5920-5927 (2010).
-
(2010)
J. Phys. Chem. B
, vol.114
, pp. 5920-5927
-
-
Singh, P.K.1
Kumbhakar, M.2
Pal, H.3
Nath, S.4
-
32
-
-
84875046818
-
5′ -UTR RNA G-quadruplexes: Translation regulation and targeting
-
Bugaut, A. & Balasubramanian, S. 5′ -UTR RNA G-quadruplexes: translation regulation and targeting. Nucleic Acids Res. 3, 1-15 (2012).
-
(2012)
Nucleic Acids Res.
, vol.3
, pp. 1-15
-
-
Bugaut, A.1
Balasubramanian, S.2
-
33
-
-
84455173130
-
Translational repression of the disintegrin and metalloprotease ADAM10 by a stable G-quadruplex secondary structure in its 5′ -untranslated region
-
Lammich, S. et al. Translational repression of the disintegrin and metalloprotease ADAM10 by a stable G-quadruplex secondary structure in its 5′ -untranslated region. J. Biol. Chem. 286, 45063-45072 (2011).
-
(2011)
J. Biol. Chem.
, vol.286
, pp. 45063-45072
-
-
Lammich, S.1
-
34
-
-
77957061503
-
The BCL-2 5′ untranslated region contains an RNA G-quadruplex-forming motif that modulates protein expression
-
Shahid, R., Bugaut, A. & Balasubramanian, S. The BCL-2 5′ untranslated region contains an RNA G-quadruplex-forming motif that modulates protein expression. Biochemistry. 49, 8300-8306 (2010).
-
(2010)
Biochemistry
, vol.49
, pp. 8300-8306
-
-
Shahid, R.1
Bugaut, A.2
Balasubramanian, S.3
-
35
-
-
73149103952
-
Repression of translation of human estrogen receptor alpha by G-quadruplex formation
-
Balkwill, G. D. et al. Repression of translation of human estrogen receptor alpha by G-quadruplex formation. Biochemistry. 48, 11487-11495 (2009).
-
(2009)
Biochemistry
, vol.48
, pp. 11487-11495
-
-
Balkwill, G.D.1
-
36
-
-
77957082956
-
A G-quadruplex structure within the 5′ -UTR of TRF2 mRNA represses translation in human cells
-
Gomez, D. et al. A G-quadruplex structure within the 5′ -UTR of TRF2 mRNA represses translation in human cells. Nucleic Acids Res. 38, 7187-7198 (2010).
-
(2010)
Nucleic Acids Res.
, vol.38
, pp. 7187-7198
-
-
Gomez, D.1
-
37
-
-
45749139174
-
Inhibition of translation in living eukaryotic cells by an RNA G-quadruplex motif
-
Arora, A. et al. Inhibition of translation in living eukaryotic cells by an RNA G-quadruplex motif. RNA 14, 1290-1296 (2008).
-
(2008)
RNA
, vol.14
, pp. 1290-1296
-
-
Arora, A.1
-
38
-
-
78650271083
-
An RNA G-quadruplex is essential for cap-independent translation initiation in human VEGF IRES
-
Morris, M. J., Negishi, Y., Pazsint, C., Schonhoft, J. D. & Basu, S. An RNA G-quadruplex is essential for cap-independent translation initiation in human VEGF IRES. J. Am. Chem. Soc. 132, 17831-17839 (2010).
-
(2010)
J. Am. Chem. Soc.
, vol.132
, pp. 17831-17839
-
-
Morris, M.J.1
Negishi, Y.2
Pazsint, C.3
Schonhoft, J.D.4
Basu, S.5
-
39
-
-
84896259966
-
C9orf72 nucleotide repeat structures initiate molecular cascades of disease
-
Haeusler, A. R. et al. C9orf72 nucleotide repeat structures initiate molecular cascades of disease. Nature 507, 195-200 (2014).
-
(2014)
Nature
, vol.507
, pp. 195-200
-
-
Haeusler, A.R.1
-
40
-
-
38549083634
-
RNAJunction: A database of RNA junctions and kissing loops for three-dimensional structural analysis and nanodesign
-
Bindewald, E., Hayes, R., Yingling, Y. G., Kasprzak, W. & Shapiro, B. A. RNAJunction: a database of RNA junctions and kissing loops for three-dimensional structural analysis and nanodesign. Nucleic Acids Res. 36, 392-397 (2008).
-
(2008)
Nucleic Acids Res.
, vol.36
, pp. 392-397
-
-
Bindewald, E.1
Hayes, R.2
Yingling, Y.G.3
Kasprzak, W.4
Shapiro, B.A.5
|