Structural basis of telomeric RNA quadruplex-acridine ligand recognition

Journal of the American Chemical Society

Volumn 133, Issue 8, 2011, Pages 2721-2728

  Collie, Gavin W ^a   Sparapani, Silvia ^a   Parkinson, Gary N ^a   Neidle, Stephen ^a  

^a UNIVERSITY OF LONDON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ACRIDINE MOLECULE; CONFORMATIONAL CHANGE; FUTURE DESIGNS; HIGHER ORDER; HUMAN TELOMERIC DNA; HYDROXYL GROUPS; LIGAND RECOGNITION; NON-CODING RNAS; QUADRUPLEX STRUCTURES; QUADRUPLEXES; RIBONUCLEOTIDES; SMALL MOLECULES; STRUCTURAL BASIS; TELOMERE FUNCTION; THERAPEUTIC INTERVENTION;

CONFORMATIONS; CRYSTAL STRUCTURE; DNA; DNA SEQUENCES; HYDROGEN BONDS; MOLECULES; PARKS; RNA; SUGARS;

NUCLEIC ACIDS;

ACRIDINE; DNA QUADRUPLEX; HYDROGEN; HYDROXYL GROUP; NUCLEOTIDE DERIVATIVE; OXYGEN; RIBONUCLEOTIDE; RNA; RNA DERIVATIVE; SUGAR; TERRA QUADRUPLEX; UNCLASSIFIED DRUG; UNTRANSLATED RNA;

ARTICLE; BINDING AFFINITY; COMPLEX FORMATION; CONTROLLED STUDY; CRYSTAL STRUCTURE; CRYSTALLIZATION; HYDROGEN BOND; MOLECULAR RECOGNITION; MOLECULE; PROTEIN LOCALIZATION; RNA CONFORMATION; RNA SEQUENCE; TELOMERE;

ACRIDINES; CRYSTALLOGRAPHY, X-RAY; G-QUADRUPLEXES; LIGANDS; MODELS, MOLECULAR; MOLECULAR STRUCTURE; RNA;

EID: 79952269800     PISSN: 00027863     EISSN: 15205126     Source Type: Journal    
DOI: 10.1021/ja109767y     Document Type: Article

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