Synthetic Toll-like receptor 7 ligand inhibits porcine reproductive and respiratory syndrome virus infection in primary porcine alveolar macrophages

Antiviral Research

Volumn 131, Issue , 2016, Pages 9-18

  Du, Yongkun ^a,b   Du, Taofeng ^a,b   Shi, Yunpeng ^a,b   Zhang, Angke ^a,b   Zhang, Chong ^a,b   Diao, Yuwen ^c,d   Jin, Guangyi ^c,d   Zhou, En Min ^a,b  

^a NORTHWEST A F UNIVERSITY   (China)

^b AGRO ENVIRONMENTAL PROTECTION INSTITUTE   (China)

^c Shenzhen University School of Medicine   (China)

^d Shenzhen Engineering Laboratory of Synthetic Biology   (China)

Author keywords

Antivirus factor; ISGs; NF B; PRRSV; TLR7

Indexed keywords

3 (4 METHYLPHENYLSULFONYL) 2 PROPENENITRILE; ANTIVIRUS AGENT; CHLOROQUINE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MESSENGER RNA; SZU 101; TOLL LIKE RECEPTOR 7; UNCLASSIFIED DRUG; 3-(4-METHYLPHENYLSULFONYL)-2-PROPENENITRILE; ADENINE; ANTIAMEBIC AGENT; CYTOKINE; NITRILE; SUCCINIC ACID DERIVATIVE; SULFONE; SZU-101;

ANIMAL CELL; ANIMAL EXPERIMENT; ANTIVIRAL ACTIVITY; ARTICLE; CELL ACTIVATION; CELLULAR IMMUNITY; CONTROLLED STUDY; EXPERIMENTAL PIG; HUMORAL IMMUNITY; IN VITRO STUDY; LUNG ALVEOLUS MACROPHAGE; NONHUMAN; PORCINE REPRODUCTIVE AND RESPIRATORY SYNDROME; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; ANALOGS AND DERIVATIVES; ANIMAL; BIOSYNTHESIS; CHEMISTRY; DRUG EFFECTS; GENE EXPRESSION REGULATION; GENETICS; HOST PATHOGEN INTERACTION; IMMUNOLOGY; METABOLISM; PHYSIOLOGY; PIG; PORCINE REPRODUCTIVE AND RESPIRATORY SYNDROME VIRUS; SYNTHESIS; VIROLOGY;

ADENINE; AMEBICIDES; ANIMALS; ANTIVIRAL AGENTS; CHLOROQUINE; CYTOKINES; GENE EXPRESSION REGULATION; HOST-PATHOGEN INTERACTIONS; IMMUNITY, CELLULAR; IMMUNITY, HUMORAL; MACROPHAGES, ALVEOLAR; NF-KAPPA B; NITRILES; PORCINE RESPIRATORY AND REPRODUCTIVE SYNDROME VIRUS; SIGNAL TRANSDUCTION; SUCCINATES; SULFONES; SWINE; TOLL-LIKE RECEPTOR 7;

EID: 84964453160     PISSN: 01663542     EISSN: 18729096     Source Type: Journal    
DOI: 10.1016/j.antiviral.2016.04.005     Document Type: Article

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