-
1
-
-
0030831145
-
Long-term cytokine production from engineered primary human stromal cells influences human hematopoiesis in an in vivo xenograft model
-
9402657
-
M.A.Dao, K.A.Pepper, J.A.Nolta. Long-term cytokine production from engineered primary human stromal cells influences human hematopoiesis in an in vivo xenograft model. Stem Cells 1997; 15:443-54; PMID:9402657; http://dx.doi.org/10.1002/stem.150443
-
(1997)
Stem Cells
, vol.15
, pp. 443-454
-
-
Dao, M.A.1
Pepper, K.A.2
Nolta, J.A.3
-
2
-
-
0035575701
-
Transduction of an IL-2 gene into human melanoma-reactive lymphocytes results in their continued growth in the absence of exogenous IL-2 and maintenance of specific antitumor activity
-
K.Liu, S.A.Rosenberg. Transduction of an IL-2 gene into human melanoma-reactive lymphocytes results in their continued growth in the absence of exogenous IL-2 and maintenance of specific antitumor activity. J Immunol 2001; 167:6356-65; PMID:11714800; http://dx.doi.org/10.4049/jimmunol.167.11.6356
-
(2001)
J Immunol
, vol.167
, pp. 6356-6365
-
-
Liu, K.1
Rosenberg, S.A.2
-
3
-
-
0038176105
-
Interleukin-2-independent proliferation of human melanoma-reactive T lymphocytes transduced with an exogenous IL-2 gene is stimulation dependent
-
12806273
-
K.Liu, S.A.Rosenberg. Interleukin-2-independent proliferation of human melanoma-reactive T lymphocytes transduced with an exogenous IL-2 gene is stimulation dependent. J Immunother 2003; 26:190-201; PMID:12806273; http://dx.doi.org/10.1097/00002371-200305000-00003
-
(2003)
J Immunother
, vol.26
, pp. 190-201
-
-
Liu, K.1
Rosenberg, S.A.2
-
4
-
-
78650176839
-
Mesenchymal stem cells for the sustained in vivo delivery of bioactive factors
-
20920540
-
T.Meyerrose, S.Olson, S.Pontow, S.Kalomoiris, Y.Jung, G.Annett, G.Bauer, J.A.Nolta. Mesenchymal stem cells for the sustained in vivo delivery of bioactive factors. Adv Drug Deliv Rev 2010; 62:1167-74; PMID:20920540; http://dx.doi.org/10.1016/j.addr.2010.09.013
-
(2010)
Adv Drug Deliv Rev
, vol.62
, pp. 1167-1174
-
-
Meyerrose, T.1
Olson, S.2
Pontow, S.3
Kalomoiris, S.4
Jung, Y.5
Annett, G.6
Bauer, G.7
Nolta, J.A.8
-
5
-
-
0033678140
-
Human mesenchymal stem cells engraft and demonstrate site-specific differentiation after in utero transplantation in sheep
-
11062543
-
K.W.Liechty, T.C.MacKenzie, A.F.Shaaban, A.Radu, A.M.Moseley, R.Deans, D.R.Marshak, A.W.Flake. Human mesenchymal stem cells engraft and demonstrate site-specific differentiation after in utero transplantation in sheep. Nat Med 2000; 6:1282-6; PMID:11062543; http://dx.doi.org/10.1038/81395
-
(2000)
Nat Med
, vol.6
, pp. 1282-1286
-
-
Liechty, K.W.1
MacKenzie, T.C.2
Shaaban, A.F.3
Radu, A.4
Moseley, A.M.5
Deans, R.6
Marshak, D.R.7
Flake, A.W.8
-
6
-
-
84855438776
-
Non-hematopoietic stem cells as factories for in vivo therapeutic protein production
-
21562594
-
L.Sanz, M.Compte, I.Guijarro-Munoz, L.Alvarez-Vallina. Non-hematopoietic stem cells as factories for in vivo therapeutic protein production. Gene Ther 2012; 19:1-7; PMID:21562594; http://dx.doi.org/10.1038/gt.2011.68
-
(2012)
Gene Ther
, vol.19
, pp. 1-7
-
-
Sanz, L.1
Compte, M.2
Guijarro-Munoz, I.3
Alvarez-Vallina, L.4
-
7
-
-
84898466874
-
Mesenchymal stem cells: Immune evasive, not immune privileged
-
24561556
-
J.A.Ankrum, J.F.Ong, J.M.Karp. Mesenchymal stem cells: immune evasive, not immune privileged. Nat Biotechnol 2014; 32:252-60; PMID:24561556; http://dx.doi.org/10.1038/nbt.2816
-
(2014)
Nat Biotechnol
, vol.32
, pp. 252-260
-
-
Ankrum, J.A.1
Ong, J.F.2
Karp, J.M.3
-
8
-
-
43049122459
-
Cell vehicle targeting strategies
-
18369326
-
J.C.Roth, D.T.Curiel, L.Pereboeva. Cell vehicle targeting strategies. Gene Ther 2008; 15:716-29; PMID:18369326; http://dx.doi.org/10.1038/gt.2008.38
-
(2008)
Gene Ther
, vol.15
, pp. 716-729
-
-
Roth, J.C.1
Curiel, D.T.2
Pereboeva, L.3
-
9
-
-
84860639631
-
Mesenchymal stem cells engineered for cancer therapy
-
21740940
-
K.Shah. Mesenchymal stem cells engineered for cancer therapy. Adv Drug Deliv Rev 2012; 64:739-48; PMID:21740940; http://dx.doi.org/10.1016/j.addr.2011.06.010
-
(2012)
Adv Drug Deliv Rev
, vol.64
, pp. 739-748
-
-
Shah, K.1
-
10
-
-
84938979765
-
Bypassing the need for pre-sensitization of cancer cells for anticancer TRAIL therapy with secretion of novel cell penetrable form of Smac from hA-MSCs as cellular delivery vehicle
-
25586349
-
M.Khorashadizadeh, M.Soleimani, H.Khanahmad, A.Fallah, M.Naderi, M.Khorramizadeh. Bypassing the need for pre-sensitization of cancer cells for anticancer TRAIL therapy with secretion of novel cell penetrable form of Smac from hA-MSCs as cellular delivery vehicle. Tumour Biol 2015; 36:4213-21; PMID:25586349; http://dx.doi.org/10.1007/s13277-015-3058-2
-
(2015)
Tumour Biol
, vol.36
, pp. 4213-4221
-
-
Khorashadizadeh, M.1
Soleimani, M.2
Khanahmad, H.3
Fallah, A.4
Naderi, M.5
Khorramizadeh, M.6
-
11
-
-
77956245585
-
Endothelial lineage cell as a vehicle for systemic delivery of cancer gene therapy
-
20801410
-
A.Z.Dudek. Endothelial lineage cell as a vehicle for systemic delivery of cancer gene therapy. Transl Res 2010; 156:136-46; PMID:20801410; http://dx.doi.org/10.1016/j.trsl.2010.07.003
-
(2010)
Transl Res
, vol.156
, pp. 136-146
-
-
Dudek, A.Z.1
-
12
-
-
81555214653
-
Induction of erythropoiesis using human vascular networks genetically engineered for controlled erythropoietin release
-
21937702
-
R.Z.Lin, A.Dreyzin, K.Aamodt, D.Li, S.C.Jaminet, A.C.Dudley, J.M.Melero-Martin. Induction of erythropoiesis using human vascular networks genetically engineered for controlled erythropoietin release. Blood 2011; 118:5420-8; PMID:21937702; http://dx.doi.org/10.1182/blood-2011-08-372946
-
(2011)
Blood
, vol.118
, pp. 5420-5428
-
-
Lin, R.Z.1
Dreyzin, A.2
Aamodt, K.3
Li, D.4
Jaminet, S.C.5
Dudley, A.C.6
Melero-Martin, J.M.7
-
13
-
-
77953477857
-
Factory neovessels: Engineered human blood vessels secreting therapeutic proteins as a new drug delivery system
-
20336155
-
M.Compte, V.Alonso-Camino, P.Santos-Valle, A.M.Cuesta, D.Sanchez-Martin, M.R.Lopez, J.L.Vicario, C.Salas, L.Sanz, L.Alvarez-Vallina. Factory neovessels: engineered human blood vessels secreting therapeutic proteins as a new drug delivery system. Gene Ther 2010; 17:745-51; PMID:20336155; http://dx.doi.org/10.1038/gt.2010.33
-
(2010)
Gene Ther
, vol.17
, pp. 745-751
-
-
Compte, M.1
Alonso-Camino, V.2
Santos-Valle, P.3
Cuesta, A.M.4
Sanchez-Martin, D.5
Lopez, M.R.6
Vicario, J.L.7
Salas, C.8
Sanz, L.9
Alvarez-Vallina, L.10
-
14
-
-
33750580560
-
Microglia: A cellular vehicle for CNS gene therapy
-
17080190
-
H.Neumann. Microglia: a cellular vehicle for CNS gene therapy. J Clin Invest 2006; 116:2857-60; PMID:17080190; http://dx.doi.org/10.1172/JCI30230
-
(2006)
J Clin Invest
, vol.116
, pp. 2857-2860
-
-
Neumann, H.1
-
15
-
-
84870515082
-
Tumor-infiltrating lymphocytes in melanoma
-
22878966
-
S.Lee, K.Margolin. Tumor-infiltrating lymphocytes in melanoma. Curr Oncol Rep 2012; 14:468-74; PMID:22878966; http://dx.doi.org/10.1007/s11912-012-0257-5
-
(2012)
Curr Oncol Rep
, vol.14
, pp. 468-474
-
-
Lee, S.1
Margolin, K.2
-
16
-
-
85048925484
-
Clinical application of genetically modified T cells in cancer therapy
-
25505964
-
M.H.Kershaw, J.A.Westwood, C.Y.Slaney, P.K.Darcy. Clinical application of genetically modified T cells in cancer therapy. Clin Transl Immunol 2014; 3:e16; PMID:25505964; http://dx.doi.org/10.1038/cti.2014.7
-
(2014)
Clin Transl Immunol
, vol.3
-
-
Kershaw, M.H.1
Westwood, J.A.2
Slaney, C.Y.3
Darcy, P.K.4
-
17
-
-
65249101637
-
The promise and potential pitfalls of chimeric antigen receptors
-
19327974
-
M.Sadelain, R.Brentjens, I.Riviere. The promise and potential pitfalls of chimeric antigen receptors. Curr Opin Immunol 2009; 21:215-23; PMID:19327974; http://dx.doi.org/10.1016/j.coi.2009.02.009
-
(2009)
Curr Opin Immunol
, vol.21
, pp. 215-223
-
-
Sadelain, M.1
Brentjens, R.2
Riviere, I.3
-
18
-
-
84877669593
-
The basic principles of chimeric antigen receptor design
-
23550147
-
M.Sadelain, R.Brentjens, I.Riviere. The basic principles of chimeric antigen receptor design. Cancer Discov 2013; 3:388-98; PMID:23550147; http://dx.doi.org/10.1158/2159-8290.CD-12-0548
-
(2013)
Cancer Discov
, vol.3
, pp. 388-398
-
-
Sadelain, M.1
Brentjens, R.2
Riviere, I.3
-
19
-
-
84938963928
-
NY-ESO-1-specific TCR-engineered T cells mediate sustained antigen-specific antitumor effects in myeloma
-
26193344
-
A.P.Rapoport, E.A.Stadtmauer, G.K.Binder-Scholl, O.Goloubeva, D.T.Vogl, S.F.Lacey, A.Z.Badros, A.Garfall, B.Weiss, J.Finklestein et al. NY-ESO-1-specific TCR-engineered T cells mediate sustained antigen-specific antitumor effects in myeloma. Nat Med 2015; 21:914-21; PMID:26193344; http://dx.doi.org/10.1038/nm.3910
-
(2015)
Nat Med
, vol.21
, pp. 914-921
-
-
Rapoport, A.P.1
Stadtmauer, E.A.2
Binder-Scholl, G.K.3
Goloubeva, O.4
Vogl, D.T.5
Lacey, S.F.6
Badros, A.Z.7
Garfall, A.8
Weiss, B.9
Finklestein, J.10
-
20
-
-
84873205156
-
Strategies to improve the clinical performance of chimeric antigen receptor-modified T cells for cancer
-
23256743
-
Q.Zhang, H.Li, J.Yang, L.Li, B.Zhang, J.Li, J.Zheng. Strategies to improve the clinical performance of chimeric antigen receptor-modified T cells for cancer. Curr Gene Ther 2013; 13:65-70; PMID:23256743; http://dx.doi.org/10.2174/156652313804806570
-
(2013)
Curr Gene Ther
, vol.13
, pp. 65-70
-
-
Zhang, Q.1
Li, H.2
Yang, J.3
Li, L.4
Zhang, B.5
Li, J.6
Zheng, J.7
-
21
-
-
84880733312
-
Adoptive T cell transfer for cancer immunotherapy in the era of synthetic biology
-
23890063
-
M.Kalos, C.H.June. Adoptive T cell transfer for cancer immunotherapy in the era of synthetic biology. Immunity 2013; 39:49-60; PMID:23890063; http://dx.doi.org/10.1016/j.immuni.2013.07.002
-
(2013)
Immunity
, vol.39
, pp. 49-60
-
-
Kalos, M.1
June, C.H.2
-
22
-
-
77950475517
-
Case report of a serious adverse event following the administration of T cells transduced with a chimeric antigen receptor recognizing ERBB2
-
20179677
-
R.A.Morgan, J.C.Yang, M.Kitano, M.E.Dudley, C.M.Laurencot, S.A.Rosenberg. Case report of a serious adverse event following the administration of T cells transduced with a chimeric antigen receptor recognizing ERBB2. Mol Ther 2010; 18:843-51; PMID:20179677; http://dx.doi.org/10.1038/mt.2010.24
-
(2010)
Mol Ther
, vol.18
, pp. 843-851
-
-
Morgan, R.A.1
Yang, J.C.2
Kitano, M.3
Dudley, M.E.4
Laurencot, C.M.5
Rosenberg, S.A.6
-
23
-
-
84873991752
-
Cancer regression and neurological toxicity following anti-MAGE-A3 TCR gene therapy
-
23377668
-
R.A.Morgan, N.Chinnasamy, D.Abate-Daga, A.Gros, P.F.Robbins, Z.Zheng, M.E.Dudley, S.A.Feldman, J.C.Yang, R.M.Sherry et al. Cancer regression and neurological toxicity following anti-MAGE-A3 TCR gene therapy. J Immunother 2013; 36:133-51; PMID:23377668; http://dx.doi.org/10.1097/CJI.0b013e3182829903
-
(2013)
J Immunother
, vol.36
, pp. 133-151
-
-
Morgan, R.A.1
Chinnasamy, N.2
Abate-Daga, D.3
Gros, A.4
Robbins, P.F.5
Zheng, Z.6
Dudley, M.E.7
Feldman, S.A.8
Yang, J.C.9
Sherry, R.M.10
-
24
-
-
84880730689
-
Cardiovascular toxicity and titin cross-reactivity of affinity-enhanced T cells in myeloma and melanoma
-
23770775
-
G.P.Linette, E.A.Stadtmauer, M.V.Maus, A.P.Rapoport, B.L.Levine, L.Emery, L.Litzky, A.Bagg, B.M.Carreno, P.J.Cimino et al. Cardiovascular toxicity and titin cross-reactivity of affinity-enhanced T cells in myeloma and melanoma. Blood 2013; 122:863-71; PMID:23770775; http://dx.doi.org/10.1182/blood-2013-03-490565
-
(2013)
Blood
, vol.122
, pp. 863-871
-
-
Linette, G.P.1
Stadtmauer, E.A.2
Maus, M.V.3
Rapoport, A.P.4
Levine, B.L.5
Emery, L.6
Litzky, L.7
Bagg, A.8
Carreno, B.M.9
Cimino, P.J.10
-
25
-
-
80051720194
-
Chimeric antigen receptor-modified T cells in chronic lymphoid leukemia
-
21830940
-
D.L.Porter, B.L.Levine, M.Kalos, A.Bagg, C.H.June. Chimeric antigen receptor-modified T cells in chronic lymphoid leukemia. N Engl J Med 2011; 365:725-33; PMID:21830940; http://dx.doi.org/10.1056/NEJMoa1103849
-
(2011)
N Engl J Med
, vol.365
, pp. 725-733
-
-
Porter, D.L.1
Levine, B.L.2
Kalos, M.3
Bagg, A.4
June, C.H.5
-
26
-
-
80051775476
-
T cells with chimeric antigen receptors have potent antitumor effects and can establish memory in patients with advanced leukemia
-
21832238
-
M.Kalos, B.L.Levine, D.L.Porter, S.Katz, S.A.Grupp, A.Bagg, C.H.June. T cells with chimeric antigen receptors have potent antitumor effects and can establish memory in patients with advanced leukemia. Sci Transl Med 2011; 3:95ra73; PMID:21832238; http://dx.doi.org/10.1126/scitranslmed.3002842
-
(2011)
Sci Transl Med
, vol.3
-
-
Kalos, M.1
Levine, B.L.2
Porter, D.L.3
Katz, S.4
Grupp, S.A.5
Bagg, A.6
June, C.H.7
-
27
-
-
84863337890
-
B-cell depletion and remissions of malignancy along with cytokine-associated toxicity in a clinical trial of anti-CD19 chimeric-antigen-receptor-transduced T cells
-
22160384
-
J.N.Kochenderfer, M.E.Dudley, S.A.Feldman, W.H.Wilson, D.E.Spaner, I.Maric, M.Stetler-Stevenson, G.Q.Phan, M.S.Hughes, R.M.Sherry et al. B-cell depletion and remissions of malignancy along with cytokine-associated toxicity in a clinical trial of anti-CD19 chimeric-antigen-receptor-transduced T cells. Blood 2012; 119:2709-20; PMID:22160384; http://dx.doi.org/10.1182/blood-2011-10-384388
-
(2012)
Blood
, vol.119
, pp. 2709-2720
-
-
Kochenderfer, J.N.1
Dudley, M.E.2
Feldman, S.A.3
Wilson, W.H.4
Spaner, D.E.5
Maric, I.6
Stetler-Stevenson, M.7
Phan, G.Q.8
Hughes, M.S.9
Sherry, R.M.10
-
28
-
-
84876005284
-
CD19-targeted T cells rapidly induce molecular remissions in adults with chemotherapy-refractory acute lymphoblastic leukemia
-
23515080
-
R.J.Brentjens, M.L.Davila, I.Riviere, J.Park, X.Wang, L.G.Cowell, S.Bartido, J.Stefanski, C.Taylor, M.Olszewska et al. CD19-targeted T cells rapidly induce molecular remissions in adults with chemotherapy-refractory acute lymphoblastic leukemia. Sci Transl Med 2013; 5:177ra38; PMID:23515080; http://dx.doi.org/10.1126/scitranslmed.3005930
-
(2013)
Sci Transl Med
, vol.5
-
-
Brentjens, R.J.1
Davila, M.L.2
Riviere, I.3
Park, J.4
Wang, X.5
Cowell, L.G.6
Bartido, S.7
Stefanski, J.8
Taylor, C.9
Olszewska, M.10
-
29
-
-
84884745916
-
Adoptive cell transfer for patients with metastatic melanoma: The potential and promise of cancer immunotherapy
-
24077405
-
G.Q.Phan, S.A.Rosenberg. Adoptive cell transfer for patients with metastatic melanoma: the potential and promise of cancer immunotherapy. Cancer Control 2013; 20:289-97; PMID:24077405
-
(2013)
Cancer Control
, vol.20
, pp. 289-297
-
-
Phan, G.Q.1
Rosenberg, S.A.2
-
30
-
-
41149097574
-
Adoptive cell transfer: A clinical path to effective cancer immunotherapy
-
18354418
-
S.A.Rosenberg, N.P.Restifo, J.C.Yang, R.A.Morgan, M.E.Dudley. Adoptive cell transfer: a clinical path to effective cancer immunotherapy. Nat Rev Cancer 2008; 8:299-308; PMID:18354418; http://dx.doi.org/10.1038/nrc2355
-
(2008)
Nat Rev Cancer
, vol.8
, pp. 299-308
-
-
Rosenberg, S.A.1
Restifo, N.P.2
Yang, J.C.3
Morgan, R.A.4
Dudley, M.E.5
-
31
-
-
80053567512
-
Cell transfer immunotherapy for metastatic solid cancer–what clinicians need to know
-
21808266
-
S.A.Rosenberg. Cell transfer immunotherapy for metastatic solid cancer–what clinicians need to know. Nat Rev Clin Oncol 2011; 8:577-85; PMID:21808266; http://dx.doi.org/10.1038/nrclinonc.2011.116
-
(2011)
Nat Rev Clin Oncol
, vol.8
, pp. 577-585
-
-
Rosenberg, S.A.1
-
32
-
-
84869885852
-
Capture, crawl, cross: The T cell code to breach the blood-brain barriers
-
22926201
-
B.Engelhardt, R.M.Ransohoff. Capture, crawl, cross: the T cell code to breach the blood-brain barriers. Trends Immunol 2012; 33:579-89; PMID:22926201; http://dx.doi.org/10.1016/j.it.2012.07.004
-
(2012)
Trends Immunol
, vol.33
, pp. 579-589
-
-
Engelhardt, B.1
Ransohoff, R.M.2
-
33
-
-
84880757177
-
Deciphering and reversing tumor immune suppression
-
23890064
-
G.T.Motz, G.Coukos. Deciphering and reversing tumor immune suppression. Immunity 2013; 39:61-73; PMID:23890064; http://dx.doi.org/10.1016/j.immuni.2013.07.005
-
(2013)
Immunity
, vol.39
, pp. 61-73
-
-
Motz, G.T.1
Coukos, G.2
-
34
-
-
33846482153
-
Effects of vascular endothelial growth factor on the lymphocyte-endothelium interactions: Identification of caveolin-1 and nitric oxide as control points of endothelial cell anergy
-
C.Bouzin, A.Brouet, J.De Vriese, J.Dewever, O.Feron. Effects of vascular endothelial growth factor on the lymphocyte-endothelium interactions: identification of caveolin-1 and nitric oxide as control points of endothelial cell anergy. J Immunol 2007; 178:1505-11; PMID:17237399; http://dx.doi.org/10.4049/jimmunol.178.3.1505
-
(2007)
J Immunol
, vol.178
, pp. 1505-1511
-
-
Bouzin, C.1
Brouet, A.2
De Vriese, J.3
Dewever, J.4
Feron, O.5
-
35
-
-
84871186557
-
Role of chemokines and chemokine receptors in shaping the effector phase of the antitumor immune response
-
23222302
-
K.Franciszkiewicz, A.Boissonnas, M.Boutet, C.Combadiere, F.Mami-Chouaib. Role of chemokines and chemokine receptors in shaping the effector phase of the antitumor immune response. Cancer Res 2012; 72:6325-32; PMID:23222302; http://dx.doi.org/10.1158/0008-5472.CAN-12-2027
-
(2012)
Cancer Res
, vol.72
, pp. 6325-6332
-
-
Franciszkiewicz, K.1
Boissonnas, A.2
Boutet, M.3
Combadiere, C.4
Mami-Chouaib, F.5
-
36
-
-
84908155316
-
Enhancement of T cell recruitment and infiltration into tumours
-
24828133
-
C.Oelkrug, J.M.Ramage. Enhancement of T cell recruitment and infiltration into tumours. Clin Exp Immunol 2014; 178:1-8; PMID:24828133; http://dx.doi.org/10.1111/cei.12382
-
(2014)
Clin Exp Immunol
, vol.178
, pp. 1-8
-
-
Oelkrug, C.1
Ramage, J.M.2
-
37
-
-
0031594280
-
TNFalpha regulation of Fas ligand expression on the vascular endothelium modulates leukocyte extravasation
-
9546786
-
M.Sata, K.Walsh. TNFalpha regulation of Fas ligand expression on the vascular endothelium modulates leukocyte extravasation. Nat Med 1998; 4:415-20; PMID:9546786; http://dx.doi.org/10.1038/nm0498-415
-
(1998)
Nat Med
, vol.4
, pp. 415-420
-
-
Sata, M.1
Walsh, K.2
-
38
-
-
0242559053
-
Endothelial expression of PD-L1 and PD-L2 down-regulates CD8+ T cell activation and cytolysis
-
14579280
-
N.Rodig, T.Ryan, J.A.Allen, H.Pang, N.Grabie, T.Chernova, E.A.Greenfield, S.C.Liang, A.H.Sharpe, A.H.Lichtman et al. Endothelial expression of PD-L1 and PD-L2 down-regulates CD8+ T cell activation and cytolysis. Eur J Immunol 2003; 33:3117-26; PMID:14579280; http://dx.doi.org/10.1002/eji.200324270
-
(2003)
Eur J Immunol
, vol.33
, pp. 3117-3126
-
-
Rodig, N.1
Ryan, T.2
Allen, J.A.3
Pang, H.4
Grabie, N.5
Chernova, T.6
Greenfield, E.A.7
Liang, S.C.8
Sharpe, A.H.9
Lichtman, A.H.10
-
39
-
-
61349100687
-
Myeloid-derived suppressor cells as regulators of the immune system
-
19197294
-
D.I.Gabrilovich, S.Nagaraj. Myeloid-derived suppressor cells as regulators of the immune system. Nat Rev Immunol 2009; 9:162-74; PMID:19197294; http://dx.doi.org/10.1038/nri2506
-
(2009)
Nat Rev Immunol
, vol.9
, pp. 162-174
-
-
Gabrilovich, D.I.1
Nagaraj, S.2
-
40
-
-
84863691003
-
Macrophages in tumor microenvironments and the progression of tumors
-
22778768
-
N.B.Hao, M.H.Lu, Y.H.Fan, Y.L.Cao, Z.R.Zhang, S.M.Yang. Macrophages in tumor microenvironments and the progression of tumors. Clin Dev Immunol 2012; 2012:948098; PMID:22778768; http://dx.doi.org/10.1155/2012/948098
-
(2012)
Clin Dev Immunol
, vol.2012
, pp. 948098
-
-
Hao, N.B.1
Lu, M.H.2
Fan, Y.H.3
Cao, Y.L.4
Zhang, Z.R.5
Yang, S.M.6
-
41
-
-
84880922175
-
Dendritic cells in the cancer microenvironment
-
23386903
-
Y.Ma, G.V.Shurin, Z.Peiyuan, M.R.Shurin. Dendritic cells in the cancer microenvironment. J Cancer 2013; 4:36-44; PMID:23386903; http://dx.doi.org/10.7150/jca.5046
-
(2013)
J Cancer
, vol.4
, pp. 36-44
-
-
Ma, Y.1
Shurin, G.V.2
Peiyuan, Z.3
Shurin, M.R.4
-
42
-
-
84896724633
-
Tumor-induced perturbations of cytokines and immune cell networks
-
24440852
-
B.Burkholder, R.Y.Huang, R.Burgess, S.Luo, V.S.Jones, W.Zhang, Z.Q.Lv, C.Y.Gao, B.L.Wang, Y.M.Zhang et al. Tumor-induced perturbations of cytokines and immune cell networks. Biochim Biophys Acta 2014; 1845:182-201; PMID:24440852; http://dx.doi.org/10.1016/j.bbcan.2014.01.004
-
(2014)
Biochim Biophys Acta
, vol.1845
, pp. 182-201
-
-
Burkholder, B.1
Huang, R.Y.2
Burgess, R.3
Luo, S.4
Jones, V.S.5
Zhang, W.6
Lv, Z.Q.7
Gao, C.Y.8
Wang, B.L.9
Zhang, Y.M.10
-
43
-
-
84877004454
-
Cytokine patterns in patients with cancer: A systematic review
-
23639322
-
B.E.Lippitz. Cytokine patterns in patients with cancer: a systematic review. Lancet Oncol 2013; 14:e218–28; PMID:23639322; http://dx.doi.org/10.1016/S1470-2045(12)70582-X
-
(2013)
Lancet Oncol
, vol.14
-
-
Lippitz, B.E.1
-
44
-
-
0034596948
-
Engagement of the PD-1 immunoinhibitory receptor by a novel B7 family member leads to negative regulation of lymphocyte activation
-
11015443
-
G.J.Freeman, A.J.Long, Y.Iwai, K.Bourque, T.Chernova, H.Nishimura, L.J.Fitz, N.Malenkovich, T.Okazaki, M.C.Byrne et al. Engagement of the PD-1 immunoinhibitory receptor by a novel B7 family member leads to negative regulation of lymphocyte activation. J Exp Med 2000; 192:1027-34; PMID:11015443; http://dx.doi.org/10.1084/jem.192.7.1027
-
(2000)
J Exp Med
, vol.192
, pp. 1027-1034
-
-
Freeman, G.J.1
Long, A.J.2
Iwai, Y.3
Bourque, K.4
Chernova, T.5
Nishimura, H.6
Fitz, L.J.7
Malenkovich, N.8
Okazaki, T.9
Byrne, M.C.10
-
45
-
-
84858766182
-
The blockade of immune checkpoints in cancer immunotherapy
-
22437870
-
D.M.Pardoll. The blockade of immune checkpoints in cancer immunotherapy. Nat Rev Cancer 2012; 12:252-64; PMID:22437870; http://dx.doi.org/10.1038/nrc3239
-
(2012)
Nat Rev Cancer
, vol.12
, pp. 252-264
-
-
Pardoll, D.M.1
-
46
-
-
35549007239
-
Co-expression of cytokine and suicide genes to enhance the activity and safety of tumor-specific cytotoxic T lymphocytes
-
17638856
-
C.Quintarelli, J.F.Vera, B.Savoldo, G.M.Giordano Attianese, M.Pule, A.E.Foster, H.E.Heslop, C.M.Rooney, M.K.Brenner, G.Dotti. Co-expression of cytokine and suicide genes to enhance the activity and safety of tumor-specific cytotoxic T lymphocytes. Blood 2007; 110:2793-802; PMID:17638856; http://dx.doi.org/10.1182/blood-2007-02-072843
-
(2007)
Blood
, vol.110
, pp. 2793-2802
-
-
Quintarelli, C.1
Vera, J.F.2
Savoldo, B.3
Giordano Attianese, G.M.4
Pule, M.5
Foster, A.E.6
Heslop, H.E.7
Rooney, C.M.8
Brenner, M.K.9
Dotti, G.10
-
47
-
-
44349117909
-
Adoptive cell therapy for patients with melanoma, using tumor-infiltrating lymphocytes genetically engineered to secrete interleukin-2
-
18444786
-
B.Heemskerk, K.Liu, M.E.Dudley, L.A.Johnson, A.Kaiser, S.Downey, Z.Zheng, T.E.Shelton, K.Matsuda, P.F.Robbins et al. Adoptive cell therapy for patients with melanoma, using tumor-infiltrating lymphocytes genetically engineered to secrete interleukin-2. Hum Gene Ther 2008; 19:496-510; PMID:18444786; http://dx.doi.org/10.1089/hum.2007.0171
-
(2008)
Hum Gene Ther
, vol.19
, pp. 496-510
-
-
Heemskerk, B.1
Liu, K.2
Dudley, M.E.3
Johnson, L.A.4
Kaiser, A.5
Downey, S.6
Zheng, Z.7
Shelton, T.E.8
Matsuda, K.9
Robbins, P.F.10
-
48
-
-
10744226452
-
IL-15 enhances the in vivo antitumor activity of tumor-reactive CD8+ T cells
-
14762166
-
C.A.Klebanoff, S.E.Finkelstein, D.R.Surman, M.K.Lichtman, L.Gattinoni, M.R.Theoret, N.Grewal, P.J.Spiess, P.A.Antony, D.C.Palmer et al. IL-15 enhances the in vivo antitumor activity of tumor-reactive CD8+ T cells. Proc Natl Acad Sci U S A 2004; 101:1969-74; PMID:14762166; http://dx.doi.org/10.1073/pnas.0307298101
-
(2004)
Proc Natl Acad Sci U S A
, vol.101
, pp. 1969-1974
-
-
Klebanoff, C.A.1
Finkelstein, S.E.2
Surman, D.R.3
Lichtman, M.K.4
Gattinoni, L.5
Theoret, M.R.6
Grewal, N.7
Spiess, P.J.8
Antony, P.A.9
Palmer, D.C.10
-
49
-
-
28244460980
-
Primary human T lymphocytes engineered with a codon-optimized IL-15 gene resist cytokine withdrawal-induced apoptosis and persist long-term in the absence of exogenous cytokine
-
C.Hsu, M.S.Hughes, Z.Zheng, R.B.Bray, S.A.Rosenberg, R.A.Morgan. Primary human T lymphocytes engineered with a codon-optimized IL-15 gene resist cytokine withdrawal-induced apoptosis and persist long-term in the absence of exogenous cytokine. J Immunol 2005; 175:7226-34; PMID:16301627; http://dx.doi.org/10.4049/jimmunol.175.11.7226
-
(2005)
J Immunol
, vol.175
, pp. 7226-7234
-
-
Hsu, C.1
Hughes, M.S.2
Zheng, Z.3
Bray, R.B.4
Rosenberg, S.A.5
Morgan, R.A.6
-
50
-
-
34250023777
-
Cytokine-independent growth and clonal expansion of a primary human CD8+ T-cell clone following retroviral transduction with the IL-15 gene
-
17353346
-
C.Hsu, S.A.Jones, C.J.Cohen, Z.Zheng, K.Kerstann, J.Zhou, P.F.Robbins, P.D.Peng, X.Shen, T.J.Gomes et al. Cytokine-independent growth and clonal expansion of a primary human CD8+ T-cell clone following retroviral transduction with the IL-15 gene. Blood 2007; 109:5168-77; PMID:17353346; http://dx.doi.org/10.1182/blood-2006-06-029173
-
(2007)
Blood
, vol.109
, pp. 5168-5177
-
-
Hsu, C.1
Jones, S.A.2
Cohen, C.J.3
Zheng, Z.4
Kerstann, K.5
Zhou, J.6
Robbins, P.F.7
Peng, P.D.8
Shen, X.9
Gomes, T.J.10
-
51
-
-
77954590000
-
Engineering CD19-specific T lymphocytes with interleukin-15 and a suicide gene to enhance their anti-lymphoma/leukemia effects and safety
-
20428207
-
V.Hoyos, B.Savoldo, C.Quintarelli, A.Mahendravada, M.Zhang, J.Vera, H.E.Heslop, C.M.Rooney, M.K.Brenner, G.Dotti. Engineering CD19-specific T lymphocytes with interleukin-15 and a suicide gene to enhance their anti-lymphoma/leukemia effects and safety. Leukemia 2010; 24:1160-70; PMID:20428207; http://dx.doi.org/10.1038/leu.2010.75
-
(2010)
Leukemia
, vol.24
, pp. 1160-1170
-
-
Hoyos, V.1
Savoldo, B.2
Quintarelli, C.3
Mahendravada, A.4
Zhang, M.5
Vera, J.6
Heslop, H.E.7
Rooney, C.M.8
Brenner, M.K.9
Dotti, G.10
-
52
-
-
0942290542
-
A strategy for treatment of Epstein-Barr virus-positive Hodgkin's disease by targeting interleukin 12 to the tumor environment using tumor antigen-specific T cells
-
14685154
-
H.J.Wagner, C.M.Bollard, S.Vigouroux, M.H.Huls, R.Anderson, H.G.Prentice, M.K.Brenner, H.E.Heslop, C.M.Rooney. A strategy for treatment of Epstein-Barr virus-positive Hodgkin's disease by targeting interleukin 12 to the tumor environment using tumor antigen-specific T cells. Cancer Gene Ther 2004; 11:81-91; PMID:14685154; http://dx.doi.org/10.1038/sj.cgt.7700664
-
(2004)
Cancer Gene Ther
, vol.11
, pp. 81-91
-
-
Wagner, H.J.1
Bollard, C.M.2
Vigouroux, S.3
Huls, M.H.4
Anderson, R.5
Prentice, H.G.6
Brenner, M.K.7
Heslop, H.E.8
Rooney, C.M.9
-
53
-
-
77956280888
-
Tumor-specific CD8+ T cells expressing interleukin-12 eradicate established cancers in lymphodepleted hosts
-
20647327
-
S.P.Kerkar, P.Muranski, A.Kaiser, A.Boni, L.Sanchez-Perez, Z.Yu, D.C.Palmer, R.N.Reger, Z.A.Borman, L.Zhang et al. Tumor-specific CD8+ T cells expressing interleukin-12 eradicate established cancers in lymphodepleted hosts. Cancer Res 2010; 70:6725-34; PMID:20647327; http://dx.doi.org/10.1158/0008-5472.CAN-10-0735
-
(2010)
Cancer Res
, vol.70
, pp. 6725-6734
-
-
Kerkar, S.P.1
Muranski, P.2
Kaiser, A.3
Boni, A.4
Sanchez-Perez, L.5
Yu, Z.6
Palmer, D.C.7
Reger, R.N.8
Borman, Z.A.9
Zhang, L.10
-
54
-
-
84863230570
-
Local delivery of interleukin-12 using T cells targeting VEGF receptor-2 eradicates multiple vascularized tumors in mice
-
22291136
-
D.Chinnasamy, Z.Yu, S.P.Kerkar, L.Zhang, R.A.Morgan, N.P.Restifo, S.A.Rosenberg. Local delivery of interleukin-12 using T cells targeting VEGF receptor-2 eradicates multiple vascularized tumors in mice. Clin Cancer Res 2012; 18:1672-83; PMID:22291136; http://dx.doi.org/10.1158/1078-0432.CCR-11-3050
-
(2012)
Clin Cancer Res
, vol.18
, pp. 1672-1683
-
-
Chinnasamy, D.1
Yu, Z.2
Kerkar, S.P.3
Zhang, L.4
Morgan, R.A.5
Restifo, N.P.6
Rosenberg, S.A.7
-
55
-
-
79953325686
-
Improving adoptive T cell therapy by targeting and controlling IL-12 expression to the tumor environment
-
21285960
-
L.Zhang, S.P.Kerkar, Z.Yu, Z.Zheng, S.Yang, N.P.Restifo, S.A.Rosenberg, R.A.Morgan. Improving adoptive T cell therapy by targeting and controlling IL-12 expression to the tumor environment. Mol Ther 2011; 19:751-9; PMID:21285960; http://dx.doi.org/10.1038/mt.2010.313
-
(2011)
Mol Ther
, vol.19
, pp. 751-759
-
-
Zhang, L.1
Kerkar, S.P.2
Yu, Z.3
Zheng, Z.4
Yang, S.5
Restifo, N.P.6
Rosenberg, S.A.7
Morgan, R.A.8
-
56
-
-
84861229798
-
Evaluation of gamma-retroviral vectors that mediate the inducible expression of IL-12 for clinical application
-
22576348
-
L.Zhang, S.A.Feldman, Z.Zheng, N.Chinnasamy, H.Xu, A.V.Nahvi, M.E.Dudley, S.A.Rosenberg, R.A.Morgan. Evaluation of gamma-retroviral vectors that mediate the inducible expression of IL-12 for clinical application. J Immunother 2012; 35:430-9; PMID:22576348; http://dx.doi.org/10.1097/CJI.0b013e31825898e8
-
(2012)
J Immunother
, vol.35
, pp. 430-439
-
-
Zhang, L.1
Feldman, S.A.2
Zheng, Z.3
Chinnasamy, N.4
Xu, H.5
Nahvi, A.V.6
Dudley, M.E.7
Rosenberg, S.A.8
Morgan, R.A.9
-
57
-
-
84858759305
-
Tumor-targeted T cells modified to secrete IL-12 eradicate systemic tumors without need for prior conditioning
-
22354001
-
H.J.Pegram, J.C.Lee, E.G.Hayman, G.H.Imperato, T.F.Tedder, M.Sadelain, R.J.Brentjens. Tumor-targeted T cells modified to secrete IL-12 eradicate systemic tumors without need for prior conditioning. Blood 2012; 119:4133-41; PMID:22354001; http://dx.doi.org/10.1182/blood-2011-12-400044
-
(2012)
Blood
, vol.119
, pp. 4133-4141
-
-
Pegram, H.J.1
Lee, J.C.2
Hayman, E.G.3
Imperato, G.H.4
Tedder, T.F.5
Sadelain, M.6
Brentjens, R.J.7
-
58
-
-
84954534981
-
IL-12 secreting tumor-targeted chimeric antigen receptor T cells eradicate ovarian tumors
-
25949921
-
M.Koneru, T.J.Purdon, D.Spriggs, S.Koneru, R.J.Brentjens. IL-12 secreting tumor-targeted chimeric antigen receptor T cells eradicate ovarian tumors. Oncoimmunology 2015; 4:e994446; PMID:25949921; http://dx.doi.org/10.4161/2162402X.2014.994446
-
(2015)
Oncoimmunology
, vol.4
-
-
Koneru, M.1
Purdon, T.J.2
Spriggs, D.3
Koneru, S.4
Brentjens, R.J.5
-
59
-
-
84922544653
-
IL-12-secreting CD19-targeted cord blood-derived T cells for the immunotherapy of B-cell acute lymphoblastic leukemia
-
25005243
-
H.J.Pegram, T.J.Purdon, D.G.van Leeuwen, K.J.Curran, S.A.Giralt, J.N.Barker, R.J.Brentjens. IL-12-secreting CD19-targeted cord blood-derived T cells for the immunotherapy of B-cell acute lymphoblastic leukemia. Leukemia 2015; 29:415-22; PMID:25005243; http://dx.doi.org/10.1038/leu.2014.215
-
(2015)
Leukemia
, vol.29
, pp. 415-422
-
-
Pegram, H.J.1
Purdon, T.J.2
van Leeuwen, D.G.3
Curran, K.J.4
Giralt, S.A.5
Barker, J.N.6
Brentjens, R.J.7
-
60
-
-
84929433571
-
Tumor-infiltrating lymphocytes genetically engineered with an inducible gene encoding interleukin-12 for the immunotherapy of metastatic melanoma
-
25695689
-
L.Zhang, R.A.Morgan, J.D.Beane, Z.Zheng, M.E.Dudley, S.H.Kassim, A.V.Nahvi, L.T.Ngo, R.M.Sherry, G.Q.Phan et al. Tumor-infiltrating lymphocytes genetically engineered with an inducible gene encoding interleukin-12 for the immunotherapy of metastatic melanoma. Clin Cancer Res 2015; 21:2278-88; PMID:25695689; http://dx.doi.org/10.1158/1078-0432.CCR-14-2085
-
(2015)
Clin Cancer Res
, vol.21
, pp. 2278-2288
-
-
Zhang, L.1
Morgan, R.A.2
Beane, J.D.3
Zheng, Z.4
Dudley, M.E.5
Kassim, S.H.6
Nahvi, A.V.7
Ngo, L.T.8
Sherry, R.M.9
Phan, G.Q.10
-
61
-
-
77951746241
-
IL-7 and IL-21 are superior to IL-2 and IL-15 in promoting human T cell-mediated rejection of systemic lymphoma in immunodeficient mice
-
20190192
-
J.C.Markley, M.Sadelain. IL-7 and IL-21 are superior to IL-2 and IL-15 in promoting human T cell-mediated rejection of systemic lymphoma in immunodeficient mice. Blood 2010; 115:3508-19; PMID:20190192; http://dx.doi.org/10.1182/blood-2009-09-241398
-
(2010)
Blood
, vol.115
, pp. 3508-3519
-
-
Markley, J.C.1
Sadelain, M.2
-
62
-
-
33947264398
-
Inhibition of tumor growth in vivo by in situ secretion of bispecific anti-CEA x anti-CD3 diabodies from lentivirally transduced human lymphocytes
-
17218946
-
M.Compte, B.Blanco, F.Serrano, A.M.Cuesta, L.Sanz, A.Bernad, P.Holliger, L.Alvarez-Vallina. Inhibition of tumor growth in vivo by in situ secretion of bispecific anti-CEA x anti-CD3 diabodies from lentivirally transduced human lymphocytes. Cancer Gene Ther 2007; 14:380-8; PMID:17218946; http://dx.doi.org/10.1038/sj.cgt.7701021
-
(2007)
Cancer Gene Ther
, vol.14
, pp. 380-388
-
-
Compte, M.1
Blanco, B.2
Serrano, F.3
Cuesta, A.M.4
Sanz, L.5
Bernad, A.6
Holliger, P.7
Alvarez-Vallina, L.8
-
63
-
-
84920691639
-
Engager T cells: A new class of antigen-specific T cells that redirect bystander T cells
-
25142939
-
K.Iwahori, S.Kakarla, M.P.Velasquez, F.Yu, Z.Yi, C.Gerken, X.T.Song, S.Gottschalk. Engager T cells: a new class of antigen-specific T cells that redirect bystander T cells. Mol Ther 2015; 23:171-8; PMID:25142939; http://dx.doi.org/10.1038/mt.2014.156
-
(2015)
Mol Ther
, vol.23
, pp. 171-178
-
-
Iwahori, K.1
Kakarla, S.2
Velasquez, M.P.3
Yu, F.4
Yi, Z.5
Gerken, C.6
Song, X.T.7
Gottschalk, S.8
-
64
-
-
84862339754
-
Tumor microenvironment and lymphocyte infiltration
-
22488275
-
G.Rahir, M.Moser. Tumor microenvironment and lymphocyte infiltration. Cancer Immunol Immunother 2012; 61:751-9; PMID:22488275; http://dx.doi.org/10.1007/s00262-012-1253-1
-
(2012)
Cancer Immunol Immunother
, vol.61
, pp. 751-759
-
-
Rahir, G.1
Moser, M.2
-
65
-
-
33748743268
-
CNS immune privilege: Hiding in plain sight
-
16972896
-
M.J.Carson, J.M.Doose, B.Melchior, C.D.Schmid, C.C.Ploix. CNS immune privilege: hiding in plain sight. Immunol Rev 2006; 213:48-65; PMID:16972896; http://dx.doi.org/10.1111/j.1600-065X.2006.00441.x
-
(2006)
Immunol Rev
, vol.213
, pp. 48-65
-
-
Carson, M.J.1
Doose, J.M.2
Melchior, B.3
Schmid, C.D.4
Ploix, C.C.5
-
66
-
-
33748748036
-
The testis in immune privilege
-
16972897
-
M.Fijak, A.Meinhardt. The testis in immune privilege. Immunol Rev 2006; 213:66-81; PMID:16972897; http://dx.doi.org/10.1111/j.1600-065X.2006.00438.x
-
(2006)
Immunol Rev
, vol.213
, pp. 66-81
-
-
Fijak, M.1
Meinhardt, A.2
-
67
-
-
33845626675
-
T-cell migration: A naive paradigm?
-
17233737
-
S.Cose. T-cell migration: a naive paradigm? Immunology 2007; 120:1-7; PMID:17233737; http://dx.doi.org/10.1111/j.1365-2567.2006.02511.x
-
(2007)
Immunology
, vol.120
, pp. 1-7
-
-
Cose, S.1
-
68
-
-
84869507166
-
Finding the optimal balance: Challenges of improving conventional cancer chemotherapy using suitable combinations with nano-sized drug delivery systems
-
22705248
-
F.Kratz, A.Warnecke. Finding the optimal balance: challenges of improving conventional cancer chemotherapy using suitable combinations with nano-sized drug delivery systems. J Control Release 2012; 164:221-35; PMID:22705248; http://dx.doi.org/10.1016/j.jconrel.2012.05.045
-
(2012)
J Control Release
, vol.164
, pp. 221-235
-
-
Kratz, F.1
Warnecke, A.2
-
69
-
-
0034661529
-
NFAT-controlled expression of GFP permits visualization and isolation of antigen-stimulated primary human T cells
-
10887106
-
E.Hooijberg, A.Q.Bakker, J.J.Ruizendaal, H.Spits. NFAT-controlled expression of GFP permits visualization and isolation of antigen-stimulated primary human T cells. Blood 2000; 96:459-66; PMID:10887106
-
(2000)
Blood
, vol.96
, pp. 459-466
-
-
Hooijberg, E.1
Bakker, A.Q.2
Ruizendaal, J.J.3
Spits, H.4
-
70
-
-
0033178680
-
Interleukin-12 therapy of cutaneous T-cell lymphoma induces lesion regression and cytotoxic T-cell responses
-
10419880
-
A.H.Rook, G.S.Wood, E.K.Yoo, R.Elenitsas, D.M.Kao, M.L.Sherman, W.K.Witmer, K.A.Rockwell, R.B.Shane, S.R.Lessin et al. Interleukin-12 therapy of cutaneous T-cell lymphoma induces lesion regression and cytotoxic T-cell responses. Blood 1999; 94:902-8; PMID:10419880
-
(1999)
Blood
, vol.94
, pp. 902-908
-
-
Rook, A.H.1
Wood, G.S.2
Yoo, E.K.3
Elenitsas, R.4
Kao, D.M.5
Sherman, M.L.6
Witmer, W.K.7
Rockwell, K.A.8
Shane, R.B.9
Lessin, S.R.10
-
71
-
-
33749684290
-
A phase II open-label study of recombinant human interleukin-12 in patients with stage IA, IB, or IIA mycosis fungoides
-
17052486
-
M.Duvic, M.L.Sherman, G.S.Wood, T.M.Kuzel, E.Olsen, F.Foss, R.J.Laliberte, J.L.Ryan, K.Zonno, A.H.Rook. A phase II open-label study of recombinant human interleukin-12 in patients with stage IA, IB, or IIA mycosis fungoides. J Am Acad Dermatol 2006; 55:807-13; PMID:17052486; PMID:12391195; http://dx.doi.org/10.1016/j.jaad.2006.06.038
-
(2006)
J Am Acad Dermatol
, vol.55
, pp. 807-813
-
-
Duvic, M.1
Sherman, M.L.2
Wood, G.S.3
Kuzel, T.M.4
Olsen, E.5
Foss, F.6
Laliberte, R.J.7
Ryan, J.L.8
Zonno, K.9
Rook, A.H.10
-
72
-
-
0036839102
-
Homeostasis of peripheral CD4+ T cells: IL-2R α and IL-2 shape a population of regulatory cells that controls CD4+ T cell numbers
-
A.R.Almeida, N.Legrand, M.Papiernik, A.A.Freitas. Homeostasis of peripheral CD4+ T cells: IL-2R α and IL-2 shape a population of regulatory cells that controls CD4+ T cell numbers. J Immunol 2002; 169:4850-60; PMID:12391195; http://dx.doi.org/10.4049/jimmunol.169.9.4850
-
(2002)
J Immunol
, vol.169
, pp. 4850-4860
-
-
Almeida, A.R.1
Legrand, N.2
Papiernik, M.3
Freitas, A.A.4
-
73
-
-
84929392967
-
A phase I clinical trial of adoptive T cell therapy using IL-12 secreting MUC-16(ecto) directed chimeric antigen receptors for recurrent ovarian cancer
-
25890361
-
M.Koneru, R.O'Cearbhaill, S.Pendharkar, D.R.Spriggs, R.J.Brentjens. A phase I clinical trial of adoptive T cell therapy using IL-12 secreting MUC-16(ecto) directed chimeric antigen receptors for recurrent ovarian cancer. J Transl Med 2015; 13:102; PMID:25890361; http://dx.doi.org/10.1186/s12967-015-0460-x
-
(2015)
J Transl Med
, vol.13
, pp. 102
-
-
Koneru, M.1
O'Cearbhaill, R.2
Pendharkar, S.3
Spriggs, D.R.4
Brentjens, R.J.5
-
74
-
-
0036428790
-
Redirecting migration of T cells to chemokine secreted from tumors by genetic modification with CXCR2
-
12427307
-
M.H.Kershaw, G.Wang, J.A.Westwood, R.K.Pachynski, H.L.Tiffany, F.M.Marincola, E.Wang, H.A.Young, P.M.Murphy, P.Hwu. Redirecting migration of T cells to chemokine secreted from tumors by genetic modification with CXCR2. Hum Gene Ther 2002; 13:1971-80; PMID:12427307; http://dx.doi.org/10.1089/10430340260355374
-
(2002)
Hum Gene Ther
, vol.13
, pp. 1971-1980
-
-
Kershaw, M.H.1
Wang, G.2
Westwood, J.A.3
Pachynski, R.K.4
Tiffany, H.L.5
Marincola, F.M.6
Wang, E.7
Young, H.A.8
Murphy, P.M.9
Hwu, P.10
-
75
-
-
77958063691
-
Enhanced tumor trafficking of GD2 chimeric antigen receptor T cells by expression of the chemokine receptor CCR2b
-
20842059
-
J.A.Craddock, A.Lu, A.Bear, M.Pule, M.K.Brenner, C.M.Rooney, A.E.Foster. Enhanced tumor trafficking of GD2 chimeric antigen receptor T cells by expression of the chemokine receptor CCR2b. J Immunother 2010; 33:780-8; PMID:20842059; http://dx.doi.org/10.1097/CJI.0b013e3181ee6675
-
(2010)
J Immunother
, vol.33
, pp. 780-788
-
-
Craddock, J.A.1
Lu, A.2
Bear, A.3
Pule, M.4
Brenner, M.K.5
Rooney, C.M.6
Foster, A.E.7
-
76
-
-
55249117972
-
Antitumor activity of EBV-specific T lymphocytes transduced with a dominant negative TGF-β receptor
-
18463534
-
A.E.Foster, G.Dotti, A.Lu, M.Khalil, M.K.Brenner, H.E.Heslop, C.M.Rooney, C.M.Bollard. Antitumor activity of EBV-specific T lymphocytes transduced with a dominant negative TGF-β receptor. J Immunother 2008; 31:500-5; PMID:18463534; http://dx.doi.org/10.1097/CJI.0b013e318177092b
-
(2008)
J Immunother
, vol.31
, pp. 500-505
-
-
Foster, A.E.1
Dotti, G.2
Lu, A.3
Khalil, M.4
Brenner, M.K.5
Heslop, H.E.6
Rooney, C.M.7
Bollard, C.M.8
-
77
-
-
84884230890
-
Blockade of TGF-β signaling greatly enhances the efficacy of TCR gene therapy of cancer
-
G.M.Bendle, C.Linnemann, L.Bies, J.Y.Song, T.N.Schumacher. Blockade of TGF-β signaling greatly enhances the efficacy of TCR gene therapy of cancer. J Immunol 2013; 191:3232-9; PMID:23940272; http://dx.doi.org/10.4049/jimmunol.1301270
-
(2013)
J Immunol
, vol.191
, pp. 3232-3239
-
-
Bendle, G.M.1
Linnemann, C.2
Bies, L.3
Song, J.Y.4
Schumacher, T.N.5
-
78
-
-
70350500225
-
STATs in cancer inflammation and immunity: A leading role for STAT3
-
19851315
-
H.Yu, D.Pardoll, R.Jove. STATs in cancer inflammation and immunity: a leading role for STAT3. Nat Rev Cancer 2009; 9:798-809; PMID:19851315; http://dx.doi.org/10.1038/nrc2734
-
(2009)
Nat Rev Cancer
, vol.9
, pp. 798-809
-
-
Yu, H.1
Pardoll, D.2
Jove, R.3
-
79
-
-
84891824280
-
STAT3 activation: A key factor in tumor immunoescape
-
24058791
-
C.Rebe, F.Vegran, H.Berger, F.Ghiringhelli. STAT3 activation: A key factor in tumor immunoescape. Jak-Stat 2013; 2:e23010; PMID:24058791; http://dx.doi.org/10.4161/jkst.23010
-
(2013)
Jak-Stat
, vol.2
-
-
Rebe, C.1
Vegran, F.2
Berger, H.3
Ghiringhelli, F.4
-
80
-
-
84860630975
-
Targeting the interleukin-6/Jak/stat pathway in human malignancies
-
22355058
-
P.Sansone, J.Bromberg. Targeting the interleukin-6/Jak/stat pathway in human malignancies. J Clin Oncol 2012; 30:1005-14; PMID:22355058; http://dx.doi.org/10.1200/JCO.2010.31.8907
-
(2012)
J Clin Oncol
, vol.30
, pp. 1005-1014
-
-
Sansone, P.1
Bromberg, J.2
-
81
-
-
84878414390
-
TLR agonists: Our best frenemy in cancer immunotherapy
-
23475577
-
S.Kaczanowska, A.M.Joseph, E.Davila. TLR agonists: our best frenemy in cancer immunotherapy. J Leukoc Biol 2013; 93:847-63; PMID:23475577; http://dx.doi.org/10.1189/jlb.1012501
-
(2013)
J Leukoc Biol
, vol.93
, pp. 847-863
-
-
Kaczanowska, S.1
Joseph, A.M.2
Davila, E.3
-
82
-
-
84941756058
-
TLR5 Ligand-Secreting T Cells Reshape the Tumor Microenvironment and Enhance Antitumor Activity
-
25795705
-
D.Geng, S.Kaczanowska, A.Tsai, K.Younger, A.Ochoa, A.P.Rapoport, S.Ostrand-Rosenberg, E.Davila. TLR5 Ligand-Secreting T Cells Reshape the Tumor Microenvironment and Enhance Antitumor Activity. Cancer Res 2015; 75:1959-71; PMID:25795705; http://dx.doi.org/10.1158/0008-5472.CAN-14-2467
-
(2015)
Cancer Res
, vol.75
, pp. 1959-1971
-
-
Geng, D.1
Kaczanowska, S.2
Tsai, A.3
Younger, K.4
Ochoa, A.5
Rapoport, A.P.6
Ostrand-Rosenberg, S.7
Davila, E.8
-
83
-
-
80455162464
-
Inducible apoptosis as a safety switch for adoptive cell therapy
-
22047558
-
A.Di Stasi, S.K.Tey, G.Dotti, Y.Fujita, A.Kennedy-Nasser, C.Martinez, K.Straathof, E.Liu, A.G.Durett, B.Grilley et al. Inducible apoptosis as a safety switch for adoptive cell therapy. N Engl J Med 2011; 365:1673-83; PMID:22047558; http://dx.doi.org/10.1056/NEJMoa1106152
-
(2011)
N Engl J Med
, vol.365
, pp. 1673-1683
-
-
Di Stasi, A.1
Tey, S.K.2
Dotti, G.3
Fujita, Y.4
Kennedy-Nasser, A.5
Martinez, C.6
Straathof, K.7
Liu, E.8
Durett, A.G.9
Grilley, B.10
-
84
-
-
84880183222
-
On employing a translationally controlled tumor protein-derived protein transduction domain analog for transmucosal delivery of drugs
-
23791976
-
H.D.Bae, K.Lee. On employing a translationally controlled tumor protein-derived protein transduction domain analog for transmucosal delivery of drugs. J Control Release 2013; 170:358-64; PMID:23791976; http://dx.doi.org/10.1016/j.jconrel.2013.06.010
-
(2013)
J Control Release
, vol.170
, pp. 358-364
-
-
Bae, H.D.1
Lee, K.2
|