Long-term cytokine production from engineered primary human stromal cells influences human hematopoiesis in an in vivo xenograft model

Stem Cells

Volumn 15, Issue 6, 1997, Pages 443-454

  Dao, Mo A ^a   Pepper, Karen A ^a   Nolta, Jan A ^a  

^a UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

Author keywords

Differentiation; Marrow stroma immune deficient mice; Retroviral mediated transduction; Stem cells; Xenotransplantation

Indexed keywords

CD34 ANTIGEN; CYTOKINE; ERYTHROPOIETIN; INTERLEUKIN 2; INTERLEUKIN 3; INTERLEUKIN 7; STEM CELL FACTOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; B LYMPHOCYTE; BURST FORMING UNIT E; CELL TRANSPLANTATION; CONTROLLED STUDY; ERYTHROPOIESIS; GENETIC ENGINEERING; HEMATOCRIT; HEMATOPOIESIS; HUMAN; HUMAN CELL; LYMPHOCYTE DIFFERENTIATION; MOUSE; NONHUMAN; STROMA CELL; T LYMPHOCYTE; XENOGRAFT;

ANIMALIA; MURINAE;

EID: 0030831145     PISSN: 10665099     EISSN: None     Source Type: Journal    
DOI: 10.1002/stem.150443     Document Type: Article

References (23)

1. Andriole GL, Mule JJ, Hansen CT et al. Evidence that lymphokine-activated killer cells and natural killer cells are distinct based on an analysis of congenitally immunodeficient mice. J Immunol 1985;135:2911-2920.
2. Pantelouris EM. Absence of thymus in a mouse mutant. Nature 1968;217:370-373.
3. Speiser DE, Stubi U, Zinkernagel R. Extrathymic positive selection of αβT-cell precursors in nude mice. Nature 1990;355:170-173.
4. Holland JM. Serotonin deficiency and prolonged bleeding in beige mice. Proc Soc Exp Biol Med 1976;151:32-38.
5. Roder J, Duwe A. The beige mutation in the mouse selectively impairs natural killer cell function. Nature 1979;278:451-454.
6. Smith HR, Yaffe LJ, Kastner DL et al. Evidence that Lyb-5 is a differentiation antigen in normal and xid mice. J Immunol 1986;136:1194-1201.
7. Karagogeos D, Rosenberg N, Wortis HH. Early arrest of B cell development in nude, X-linked immunodeficient mice. Eur J Immunol 1986;16:1125-1132.
8. Nolta JA, Hanley MB, Kohn DB. Sustained human hematopoiesis in immunodeficient mice by co-transplantation of marrow stroma expressing human IL-3: analysis of gene transduction of long-lived progenitors. Blood 1994;83:3041-3049.
9. Nolta JA, Dao MA, Wells S et al. Transduction of pluripotent human hematopoietic stem cells demonstrated by clonal analysis after engraftment in immune-deficient mice. Proc Natl Acad Sci USA 1996;93:2414-2419.
10. Ball TC, Hirayama F, Ogawa M. Modulation of early B lymphopoiesis by interleukin-3. Exp Hematol 1996;24:1225-1231.
11. Yonemura Y, Ku H, Hirayama F et al. Interleukin 3 or interleukin 1 abrogates the reconstituting ability of hematopoietic stem cells. Proc Natl Acad Sci USA 1996;93:4040-4047.
12. Miller AD, Rosman GJ. Improved retroviral vectors for gene transfer and expression. Biotechniques 1989;7:980-988.
13. Hannum C, Culpepper J, Campbell D et al. Ligand for FLT3/FLK2 receptor tyrosine kinase regulates growth of hematopoietic stem cells and is encoded by variant RNAs. Nature 1994;368:643-647.
14. Miller AD, Buttimore C. Redesign of retrovirus packaging cell lines to avoid recombination leading to helper virus production. Mol Cell Biol 1986;6:2895-2905.
15. Morgan RA, Cornetta K, Anderson WF. Applications of the polymerase chain reaction in retroviral mediated gene transfer and the analysis of gene marked human TIL cells. Hum Gene Ther 1990;1:257-264.
16. + cells from HTV-1 infected donors using retroviral vectors containing anti-HIV-1 genes. Blood 1997;89:7-13.
17. - thymocytes. J Immunol 1991;146:3068-3077.
18. Godfrey DI, Zlotnik A. Control points in early T-cell development. Immunol Today 1993;14:547-553.
19. Jacobsen FW, Veiby OP, Skjonsberg C et al. Novel role of interleukin 7 in myelopoiesis: stimulation of primitive hematopoietic progenitor cells. J Exp Med 1993;178:1777-1782.
20. Anderson DM, Lyman SD, Baird A et al. Molecular cloning of mast cell growth factor, a hematopoietin that is active in membrane bound and soluble forms. Cell 1990;63:235-243.
21. Caruana G, Ashman LK, Fujita J et al. Responses of the murine myeloid cell line FDC-P1 to soluble and membrane-bound forms of steel factor (SLF). Exp Hematol 1993;21:761-768.
22. Greiner DL, Shultz LD, Yates J et al. Improved engraftment of human spleen cells in NOD/LtSz-scid/scid mice as compared with C.B-17-scid/scid mice. Am J Pathol 1995;146:888-902.
23. Dexter TM, Garland JM, Testa NG, eds. Colony Stimulating Factors: Immunology Series. Volume 49. New York: Marcel Dekker, Inc., 1990:177-203.