Protostadienol synthase from Aspergillus fumigatus: Functional conversion into lanosterol synthase

Biochemical and Biophysical Research Communications

Volumn 391, Issue 1, 2010, Pages 899-902

  Kimura, Miki ^a   Kushiro, Tetsuo ^a   Shibuya, Masaaki ^a   Ebizuka, Yutaka ^a   Abe, Ikuro ^a  

^a UNIVERSITY OF TOKYO   (Japan)

Author keywords

Helvolic acid; Lanosterol synthase; Oxidosqualene cyclase; Protostadienol synthase; Steroidal antibiotics

Indexed keywords

CATION; FUNGAL ENZYME; LANOSTEROL; LANOSTEROL SYNTHASE; OXIDOSQUALENE CYCLASE; PROTOSTADIENOL CYCLASE; UNCLASSIFIED DRUG;

ARTICLE; ASPERGILLUS FUMIGATUS; BINDING AFFINITY; CARBOXY TERMINAL SEQUENCE; CONTROLLED STUDY; ENZYME ACTIVE SITE; ENZYME ANALYSIS; ENZYME SUBSTRATE; MOLECULAR INTERACTION; MOLECULAR MODEL; MUTANT; NONHUMAN; PRIORITY JOURNAL; STRUCTURE ACTIVITY RELATION;

AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; ASPERGILLUS FUMIGATUS; CYCLIZATION; FUSIDIC ACID; INTRAMOLECULAR TRANSFERASES; MOLECULAR SEQUENCE DATA; SQUALENE; TRITERPENES;

ASPERGILLUS FUMIGATUS; FUNGI;

EID: 72949113214     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2009.11.160     Document Type: Article

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