Amphotericin primarily kills yeast by simply binding ergosterol

Proceedings of the National Academy of Sciences of the United States of America

Volumn 109, Issue 7, 2012, Pages 2234-2239

  Gray, Kaitlyn C ^a   Palacios, Daniel S ^a   Dailey, Ian ^a   Endo, Matthew M ^a   Uno, Brice E ^a   Wilcock, Brandon C ^a   Burke, Martin D ^a  

^a UNIVERSITY OF ILLINOIS AT URBANA CHAMPAIGN   (United States)

Author keywords

N methyliminodiacetic acid boronates; Protein like functions; Small molecules

Indexed keywords

2 OLEOYL 1 PALMITOYLPHOSPHATIDYLCHOLINE; AMPHOTERICIN B; AMPHOTERICIN B DERIVATIVE; ERGOSTEROL; ION CHANNEL; LIPOSOME; MACROLIDE; NATAMYCIN; POLYENE;

ANIMAL CELL; ARTICLE; CANDIDA ALBICANS; CELL FUNCTION; CELL VACUOLE; CHANNEL GATING; CONCENTRATION RESPONSE; CROSS COUPLING REACTION; CYCLIZATION; DEPROTECTION REACTION; DRUG POTENCY; FUNGICIDAL ACTIVITY; HYDROGEN BOND; LIPID BILAYER; MEMBRANE PERMEABILITY; MOLECULE; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; SACCHAROMYCES CEREVISIAE; SYNTHESIS; YEAST; YEAST CELL;

AMPHOTERICIN B; ANTIFUNGAL AGENTS; ERGOSTEROL; SACCHAROMYCES CEREVISIAE;

EUKARYOTA;

EID: 84857134391     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1117280109     Document Type: Article

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