Forebrain neuronal specific ablation of p53 gene provides protection in a cortical ischemic stroke model

Neuroscience

Volumn 295, Issue , 2015, Pages 1-10

  Filichia, E ^a   Shen, H ^b   Zhou, X ^a   Qi, X ^c   Jin, K ^a   Greig, N ^d   Hoffer, B ^a   Luo, Y ^a  

^a CASE WESTERN RESERVE UNIVERSITY   (United States)

^b National Institute on Drug Abuse   (United States)

^c CASE WESTERN RESERVE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d NATIONAL INSTITUTE ON AGING   (United States)

Author keywords

Conditional p53 knockout; Neuroprotection; Stroke

Indexed keywords

ACTIN BINDING PROTEIN; AIF1 PROTEIN, MOUSE; CALCIUM BINDING PROTEIN; CALCIUM CALMODULIN DEPENDENT PROTEIN KINASE KINASE; CAMKK2 PROTEIN, MOUSE; ENOLASE; GLIAL FIBRILLARY ACIDIC PROTEIN; MICROTUBULE ASSOCIATED PROTEIN; MTAP2 PROTEIN, MOUSE; PROTEIN P53;

ADULT; ANALYSIS OF VARIANCE; ANIMAL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BEHAVIOR DISORDER; BRAIN INFARCTION SIZE; BRAIN ISCHEMIA; BRAIN TISSUE; CELL DEATH; CELL SURVIVAL; COMPLICATION; CONTROLLED STUDY; DEFICIENCY; DISEASE MODEL; ETIOLOGY; FOREBRAIN; GENE DELETION; GENE EXPRESSION REGULATION; GENE FUNCTION; GENETIC MANIPULATION; GENETICS; IMMUNOHISTOCHEMISTRY; KNOCKOUT MOUSE; LOCOMOTION; MALE; METABOLISM; MOTOR DYSFUNCTION; MOUSE; NERVE CELL; NERVE CELL NECROSIS; NEUROPROTECTION; NONHUMAN; P53 GENE; PATHOLOGY; PHYSIOLOGY; PREVENTION; PRIORITY JOURNAL; PROTEIN EXPRESSION; STROKE; UPREGULATION; WILD TYPE MOUSE;

ANALYSIS OF VARIANCE; ANIMALS; BRAIN ISCHEMIA; CALCIUM-BINDING PROTEINS; CALCIUM-CALMODULIN-DEPENDENT PROTEIN KINASE KINASE; CELL DEATH; COMPLICATIONS; DEFICIENCY; DISEASE MODELS, ANIMAL; ETIOLOGY; GENETICS; GLIAL FIBRILLARY ACIDIC PROTEIN; LOCOMOTION; MALE; METABOLISM; MICE; MICE, KNOCKOUT; MICROFILAMENT PROTEINS; MICROTUBULE-ASSOCIATED PROTEINS; NEURONS; PATHOLOGY; PHOSPHOPYRUVATE HYDRATASE; PHYSIOLOGY; PREVENTION AND CONTROL; PROSENCEPHALON; STROKE; TUMOR SUPPRESSOR PROTEIN P53; UP-REGULATION;

EID: 84964284793     PISSN: 03064522     EISSN: 18737544     Source Type: Journal    
DOI: 10.1016/j.neuroscience.2015.03.018     Document Type: Article

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