메뉴 건너뛰기




Volumn 34, Issue 1, 2014, Pages 2-18

Selective neuronal loss in ischemic stroke and cerebrovascular disease

Author keywords

11C flumazenil; carotid disease; cerebral ischemia; neuronal death; PET; vascular cognitive impairment

Indexed keywords

4 AMINOBUTYRIC ACID RECEPTOR STIMULATING AGENT; AMPA RECEPTOR ANTAGONIST; ANTIDEPRESSANT AGENT; FLUMAZENIL C 11; SEROTONIN UPTAKE INHIBITOR;

EID: 84891825730     PISSN: 0271678X     EISSN: 15597016     Source Type: Journal    
DOI: 10.1038/jcbfm.2013.188     Document Type: Review
Times cited : (181)

References (174)
  • 3
    • 0021367637 scopus 로고
    • Selective necrosis and total necrosis in focal cerebral ischemia. Neuropathologic observations on experimental middle cerebral artery occlusion in the macaque monkey
    • DeGirolami U, Crowell RM, Marcoux FW. Selective necrosis and total necrosis in focal cerebral ischemia. Neuropathologic observations on experimental middle cerebral artery occlusion in the macaque monkey. J Neuropathol Exp Neurol 1984; 43: 57-71.
    • (1984) J Neuropathol Exp Neurol , vol.43 , pp. 57-71
    • Degirolami, U.1    Crowell, R.M.2    Marcoux, F.W.3
  • 4
    • 0024204729 scopus 로고
    • Biological differences between ischemia, hypoglycemia, and epilepsy
    • Auer RN, Siesjo BK. Biological differences between ischemia, hypoglycemia, and epilepsy. Ann Neurol 1988; 24: 699-707.
    • (1988) Ann Neurol , vol.24 , pp. 699-707
    • Auer, R.N.1    Siesjo, B.K.2
  • 5
    • 0001360146 scopus 로고
    • Zur pathogenese örtlich elektiver gehirnveränderungen
    • Spielmeyer W. Zur pathogenese örtlich elektiver gehirnverä nderungen. Z Ges Neurol Psych 1925; 99: 756-776.
    • (1925) Z Ges Neurol Psych , vol.99 , pp. 756-776
    • Spielmeyer, W.1
  • 6
    • 0000209653 scopus 로고
    • Pathologische anatomie der kreislaufstörungen
    • Spatz H. Pathologische anatomie der kreislaufstörungen. Z Neurol 1939; 167: 301-324.
    • (1939) Z Neurol , vol.167 , pp. 301-324
    • Spatz, H.1
  • 7
    • 0020573697 scopus 로고
    • Functional recovery of cortical neurons as related to degree and duration of ischemia
    • Heiss WD, Rosner G. Functional recovery of cortical neurons as related to degree and duration of ischemia. Ann Neurol 1983; 14: 294-301.
    • (1983) Ann Neurol , vol.14 , pp. 294-301
    • Heiss, W.D.1    Rosner, G.2
  • 8
    • 0019983573 scopus 로고
    • Incomplete cerebral infarction-focal incomplete ischemic tissue necrosis not leading to emollision
    • Lassen NA. Incomplete cerebral infarction-focal incomplete ischemic tissue necrosis not leading to emollision. Stroke 1982; 13: 522-523.
    • (1982) Stroke , vol.13 , pp. 522-523
    • Lassen, N.A.1
  • 10
    • 0025083592 scopus 로고
    • Ischemia-induced slowly progressive neuronal damage in the rat brain
    • Nakano S, Kogure K, Fujikura H. Ischemia-induced slowly progressive neuronal damage in the rat brain. Neuroscience 1990; 38: 115-124.
    • (1990) Neuroscience , vol.38 , pp. 115-124
    • Nakano, S.1    Kogure, K.2    Fujikura, H.3
  • 11
    • 0030669916 scopus 로고    scopus 로고
    • Incomplete infarct and delayed neuronal death after transient middle cerebral artery occlusion in rats
    • Garcia JH, Liu KF, Ye ZR, Gutierrez JA. Incomplete infarct and delayed neuronal death after transient middle cerebral artery occlusion in rats. Stroke 1997; 28: 2303-2309.
    • (1997) Stroke , vol.28 , pp. 2303-2309
    • Garcia, J.H.1    Liu, K.F.2    Ye, Z.R.3    Gutierrez, J.A.4
  • 12
    • 0027717434 scopus 로고
    • The case of aphasia or neglect after striatocapsular infarction
    • Weiller C, Willmes K, Reiche W, Thron A, Isensee C, Buell U et al. The case of aphasia or neglect after striatocapsular infarction. Brain 1993; 116: 1509-1525.
    • (1993) Brain , vol.116 , pp. 1509-1525
    • Weiller, C.1    Willmes, K.2    Reiche, W.3    Thron, A.4    Isensee, C.5    Buell, U.6
  • 13
    • 0027495973 scopus 로고
    • In vivo mapping of brain benzodiazepine receptor changes by positron emission tomography after focal ischemia in the anesthetized baboon
    • Sette G, Baron JC, Young AR, Miyazawa H, Tillet I, Barre L et al. In vivo mapping of brain benzodiazepine receptor changes by positron emission tomography after focal ischemia in the anesthetized baboon. Stroke 1993; 24: 2046-2057.
    • (1993) Stroke , vol.24 , pp. 2046-2057
    • Sette, G.1    Baron, J.C.2    Young, A.R.3    Miyazawa, H.4    Tillet, I.5    Barre, L.6
  • 14
    • 26044457972 scopus 로고    scopus 로고
    • Curvilinear t1 hyperintense lesions representing cortical necrosis after cerebral infarction
    • Kinoshita T, Ogawa T, Yoshida Y, Tamura H, Kado H, Okudera T. Curvilinear t1 hyperintense lesions representing cortical necrosis after cerebral infarction. Neuroradiology 2005; 47: 647-651.
    • (2005) Neuroradiology , vol.47 , pp. 647-651
    • Kinoshita, T.1    Ogawa, T.2    Yoshida, Y.3    Tamura, H.4    Kado, H.5    Okudera, T.6
  • 16
    • 34247548768 scopus 로고    scopus 로고
    • Histopathology of cerebral ischemia
    • Mohr DC J. P, Grotta James Philip Wolf eds, London: Churchill Livingstone
    • Auer RN. Histopathology Of Cerebral Ischemia. In: Mohr DC J. P, Grotta James, Philip Wolf eds. Stroke: Pathophysiology, diagnosis and management London: Churchill Livingstone, 2004 821-828.
    • (2004) Stroke: Pathophysiology, Diagnosis and Management , pp. 821-828
    • Auer, R.N.1
  • 17
    • 84872781954 scopus 로고    scopus 로고
    • Characterizing infarction and selective neuronal loss following temporary focal cerebral ischemia in the rat: A multi-modality imaging study
    • Ejaz S, Williamson DJ, Ahmed T, Sitnikov S, Hong YT, Sawiak SJ et al. Characterizing infarction and selective neuronal loss following temporary focal cerebral ischemia in the rat: a multi-modality imaging study. Neurobiol Dis 2013; 51: 120-132.
    • (2013) Neurobiol Dis , vol.51 , pp. 120-132
    • Ejaz, S.1    Williamson, D.J.2    Ahmed, T.3    Sitnikov, S.4    Hong, Y.T.5    Sawiak, S.J.6
  • 18
    • 0020051129 scopus 로고
    • Delayed neuronal death in the gerbil hippocampus following ischemia
    • Kirino T. Delayed neuronal death in the gerbil hippocampus following ischemia. Brain Res 1982; 239: 57-69.
    • (1982) Brain Res , vol.239 , pp. 57-69
    • Kirino, T.1
  • 19
    • 0020067965 scopus 로고
    • Temporal profile of neuronal damage in a model of transient forebrain ischemia
    • Pulsinelli WA, Brierley JB, Plum F. Temporal profile of neuronal damage in a model of transient forebrain ischemia. Ann Neurol 1982; 11: 491-498.
    • (1982) Ann Neurol , vol.11 , pp. 491-498
    • Pulsinelli, W.A.1    Brierley, J.B.2    Plum, F.3
  • 20
    • 0023390566 scopus 로고
    • Delayed hippocampal damage in humans following cardiorespiratory arrest
    • Petito CK, Feldmann E, Pulsinelli WA, Plum F. Delayed hippocampal damage in humans following cardiorespiratory arrest. Neurology 1987; 37: 1281-1286.
    • (1987) Neurology , vol.37 , pp. 1281-1286
    • Petito, C.K.1    Feldmann, E.2    Pulsinelli, W.A.3    Plum, F.4
  • 21
    • 0022871903 scopus 로고
    • Human amnesia and the medial temporal region: Enduring memory impairment following a bilateral lesion limited to field ca1 of the hippocampus
    • Zola-Morgan S, Squire LR, Amaral DG. Human amnesia and the medial temporal region: enduring memory impairment following a bilateral lesion limited to field ca1 of the hippocampus. J Neurosci 1986; 6: 2950-2967.
    • (1986) J Neurosci , vol.6 , pp. 2950-2967
    • Zola-Morgan, S.1    Squire, L.R.2    Amaral, D.G.3
  • 23
    • 0028083253 scopus 로고
    • Specific changes in human brain following reperfusion after cardiac arrest
    • Fujioka M, Okuchi K, Sakaki T, Hiramatsu K, Miyamoto S, Iwasaki S. Specific changes in human brain following reperfusion after cardiac arrest. Stroke 1994; 25: 2091-2095.
    • (1994) Stroke , vol.25 , pp. 2091-2095
    • Fujioka, M.1    Okuchi, K.2    Sakaki, T.3    Hiramatsu, K.4    Miyamoto, S.5    Iwasaki, S.6
  • 25
    • 30944464200 scopus 로고    scopus 로고
    • Clinical significance of T1-weighted MR images following transient cerebral ischemia
    • Aoe H, Takeda Y, Kawahara H, Tanaka A, Morita K. Clinical significance of T1-weighted MR images following transient cerebral ischemia. J Neurol Sci 2006; 241: 19-24.
    • (2006) J Neurol Sci , vol.241 , pp. 19-24
    • Aoe, H.1    Takeda, Y.2    Kawahara, H.3    Tanaka, A.4    Morita, K.5
  • 27
    • 84869213443 scopus 로고    scopus 로고
    • Acute symptomatic hypoglycaemia mimicking ischaemic stroke on imaging: A systemic review
    • Yong AW, Morris Z, Shuler K, Smith C, Wardlaw J. Acute symptomatic hypoglycaemia mimicking ischaemic stroke on imaging: a systemic review. BMC Neurol 2012; 12: 139.
    • (2012) BMC Neurol , vol.12 , pp. 139
    • Yong, A.W.1    Morris, Z.2    Shuler, K.3    Smith, C.4    Wardlaw, J.5
  • 28
    • 84984763363 scopus 로고    scopus 로고
    • Mechanisms, challenges and opportunities in stroke
    • Lo EH, Dalkara T, Moskowitz MA. Mechanisms, challenges and opportunities in stroke. Nat Rev Neurosci 2003; 4: 399-415.
    • (2003) Nat Rev Neurosci , vol.4 , pp. 399-415
    • Lo, E.H.1    Dalkara, T.2    Moskowitz, M.A.3
  • 29
    • 84856460696 scopus 로고    scopus 로고
    • Visualizing cell death in experimental focal cerebral ischemia: Promises, problems, and perspectives
    • Zille M, Farr TD, Przesdzing I, Muller J, Sommer C, Dirnagl U et al. Visualizing cell death in experimental focal cerebral ischemia: promises, problems, and perspectives. J Cereb Blood Flow Metab 2012; 32: 213-231.
    • (2012) J Cereb Blood Flow Metab , vol.32 , pp. 213-231
    • Zille, M.1    Farr, T.D.2    Przesdzing, I.3    Muller, J.4    Sommer, C.5    Dirnagl, U.6
  • 30
    • 0037162691 scopus 로고    scopus 로고
    • Regeneration of hippocampal pyramidal neurons after ischemic brain injury by recruitment of endogenous neural progenitors
    • Nakatomi H, Kuriu T, Okabe S, Yamamoto S, Hatano O, Kawahara N et al. Regeneration of hippocampal pyramidal neurons after ischemic brain injury by recruitment of endogenous neural progenitors. Cell 2002; 110: 429-441.
    • (2002) Cell , vol.110 , pp. 429-441
    • Nakatomi, H.1    Kuriu, T.2    Okabe, S.3    Yamamoto, S.4    Hatano, O.5    Kawahara, N.6
  • 31
    • 0037148929 scopus 로고    scopus 로고
    • Treatment of comatose survivors of out-of-hospital cardiac arrest with induced hypothermia
    • Bernard SA, Gray TW, Buist MD, Jones BM, Silvester W, Gutteridge G et al. Treatment of comatose survivors of out-of-hospital cardiac arrest with induced hypothermia. N Engl J Med 2002; 346: 557-563.
    • (2002) N Engl J Med , vol.346 , pp. 557-563
    • Bernard, S.A.1    Gray, T.W.2    Buist, M.D.3    Jones, B.M.4    Silvester, W.5    Gutteridge, G.6
  • 32
    • 0037148926 scopus 로고    scopus 로고
    • Mild therapeutic hypothermia to improve the neurologic outcome after cardiac arrest
    • Group HaCAS. Mild therapeutic hypothermia to improve the neurologic outcome after cardiac arrest. N Engl J Med 2002; 346: 549-556.
    • (2002) N Engl J Med , vol.346 , pp. 549-556
  • 33
    • 33644807652 scopus 로고    scopus 로고
    • How healthy is the acutely reperfused ischemic penumbra?
    • Baron JC. How healthy is the acutely reperfused ischemic penumbra? Cere-brovasc Dis 2005; 20(Suppl 2): 25-31.
    • (2005) Cere-brovasc Dis , vol.20 , Issue.SUPPL. 2 , pp. 25-31
    • Baron, J.C.1
  • 34
    • 41249095350 scopus 로고    scopus 로고
    • Decreased chronic-stage cortical 11c-flumazenil binding after focal ischemia-reperfusion in baboons: A marker of selective neuronal loss?
    • Giffard C, Landeau B, Kerrouche N, Young AR, Barre L, Baron JC. Decreased chronic-stage cortical 11c-flumazenil binding after focal ischemia-reperfusion in baboons: a marker of selective neuronal loss? Stroke 2008; 39: 991-999.
    • (2008) Stroke , vol.39 , pp. 991-999
    • Giffard, C.1    Landeau, B.2    Kerrouche, N.3    Young, A.R.4    Barre, L.5    Baron, J.C.6
  • 35
    • 0032959527 scopus 로고    scopus 로고
    • Novel brain ischemic change on MRI. Delayed ischemic hyperintensity on T1-weighted images and selective neuronal death in the caudoputamen of rats after brief focal ischemia
    • Fujioka M, Taoka T, Matsuo Y, Hiramatsu KI, Sakaki T. Novel brain ischemic change on MRI. Delayed ischemic hyperintensity on T1-weighted images and selective neuronal death in the caudoputamen of rats after brief focal ischemia. Stroke 1999; 30: 1043-1046.
    • (1999) Stroke , vol.30 , pp. 1043-1046
    • Fujioka, M.1    Taoka, T.2    Matsuo, Y.3    Hiramatsu, K.I.4    Sakaki, T.5
  • 36
    • 0030769136 scopus 로고    scopus 로고
    • Microglial and macrophage reactions mark progressive changes and define the penumbra in the rat neocortex and striatum after transient middle cerebral artery occlusion
    • Lehrmann E, Christensen T, Zimmer J, Diemer NH, Finsen B. Microglial and macrophage reactions mark progressive changes and define the penumbra in the rat neocortex and striatum after transient middle cerebral artery occlusion. J Comp Neurol 1997; 386: 461-476.
    • (1997) J Comp Neurol , vol.386 , pp. 461-476
    • Lehrmann, E.1    Christensen, T.2    Zimmer, J.3    Diemer, N.H.4    Finsen, B.5
  • 37
    • 0032857920 scopus 로고    scopus 로고
    • Reversal of acute apparent diffusion coefficient abnormalities and delayed neuronal death following transient focal cerebral ischemia in rats
    • Li F, Han SS, Tatlisumak T, Liu KF, Garcia JH, Sotak CH et al. Reversal of acute apparent diffusion coefficient abnormalities and delayed neuronal death following transient focal cerebral ischemia in rats. Ann Neurol 1999; 46: 333-342.
    • (1999) Ann Neurol , vol.46 , pp. 333-342
    • Li, F.1    Han, S.S.2    Tatlisumak, T.3    Liu, K.F.4    Garcia, J.H.5    Sotak, C.H.6
  • 38
    • 52049112072 scopus 로고    scopus 로고
    • Very brief focal ischemia simulating transient ischemic attacks (TIAs) can injure brain and induce hsp70 protein
    • Zhan X, Kim C, Sharp FR. Very brief focal ischemia simulating transient ischemic attacks (TIAs) can injure brain and induce hsp70 protein. Brain Res 2008; 1234: 183-197.
    • (2008) Brain Res , vol.1234 , pp. 183-197
    • Zhan, X.1    Kim, C.2    Sharp, F.R.3
  • 39
    • 29144489188 scopus 로고    scopus 로고
    • Temporal profile of T2-weighted MRI distinguishes between pannecrosis and selective neuronal death after transient focal cerebral ischemia in the rat
    • Wegener S, Weber R, Ramos-Cabrer P, Uhlenkueken U, Sprenger C, Wiedermann D et al. Temporal profile of T2-weighted MRI distinguishes between pannecrosis and selective neuronal death after transient focal cerebral ischemia in the rat. J Cereb Blood Flow Metab 2006; 26: 38-47.
    • (2006) J Cereb Blood Flow Metab , vol.26 , pp. 38-47
    • Wegener, S.1    Weber, R.2    Ramos-Cabrer, P.3    Uhlenkueken, U.4    Sprenger, C.5    Wiedermann, D.6
  • 40
    • 0034093098 scopus 로고    scopus 로고
    • Transient and permanent resolution of ischemic lesions on diffusion-weighted imaging after brief periods of focal ischemia in rats: Correlation with histopathology
    • Li F, Liu KF, Silva MD, Omae T, Sotak CH, Fenstermacher JD et al. Transient and permanent resolution of ischemic lesions on diffusion-weighted imaging after brief periods of focal ischemia in rats: correlation with histopathology. Stroke 2000; 31: 946-954.
    • (2000) Stroke , vol.31 , pp. 946-954
    • Li, F.1    Liu, K.F.2    Silva, M.D.3    Omae, T.4    Sotak, C.H.5    Fenstermacher, J.D.6
  • 41
    • 0034788225 scopus 로고    scopus 로고
    • Reversal of early diffusion-weighted magnetic resonance imaging abnormalities does not necessarily reflect tissue salvage in experimental cerebral ischemia
    • Ringer TM, Neumann-Haefelin T, Sobel RA, Moseley ME, Yenari MA. Reversal of early diffusion-weighted magnetic resonance imaging abnormalities does not necessarily reflect tissue salvage in experimental cerebral ischemia. Stroke 2001; 32: 2362-2369.
    • (2001) Stroke , vol.32 , pp. 2362-2369
    • Ringer, T.M.1    Neumann-Haefelin, T.2    Sobel, R.A.3    Moseley, M.E.4    Yenari, M.A.5
  • 42
    • 33749031809 scopus 로고    scopus 로고
    • Long-term changes of functional MRI-based brain function, behavioral status, and histopathology after transient focal cerebral ischemia in rats
    • Sicard KM, Henninger N, Fisher M, Duong TQ, Ferris CF. Long-term changes of functional MRI-based brain function, behavioral status, and histopathology after transient focal cerebral ischemia in rats. Stroke 2006; 37: 2593-2600.
    • (2006) Stroke , vol.37 , pp. 2593-2600
    • Sicard, K.M.1    Henninger, N.2    Fisher, M.3    Duong, T.Q.4    Ferris, C.F.5
  • 43
    • 0031953599 scopus 로고    scopus 로고
    • Dynamics of cerebral tissue injury and perfusion after temporary hypoxia-ischemia in the rat: Evidence for region-specific sensitivity and delayed damage
    • Dijkhuizen RM, Knollema S, van der Worp HB, Ter Horst GJ, De Wildt DJ, Berkelbach van der Sprenkel JW et al. Dynamics of cerebral tissue injury and perfusion after temporary hypoxia-ischemia in the rat: evidence for region-specific sensitivity and delayed damage. Stroke 1998; 29: 695-704.
    • (1998) Stroke , vol.29 , pp. 695-704
    • Dijkhuizen, R.M.1    Knollema, S.2    Van Der Worp, H.B.3    Ter Horst, G.J.4    De Wildt, D.J.5    Berkelbach Van Der Sprenkel, J.W.6
  • 45
    • 0242499487 scopus 로고    scopus 로고
    • Selective neuronal vulnerability following mild focal brain ischemia in the mouse
    • Katchanov J, Waeber C, Gertz K, Gietz A, Winter B, Bruck W et al. Selective neuronal vulnerability following mild focal brain ischemia in the mouse. Brain Pathol 2003; 13: 452-464.
    • (2003) Brain Pathol , vol.13 , pp. 452-464
    • Katchanov, J.1    Waeber, C.2    Gertz, K.3    Gietz, A.4    Winter, B.5    Bruck, W.6
  • 46
  • 47
    • 15944417808 scopus 로고    scopus 로고
    • Subcortical lesions after transient thread occlusion in the rat: T2-weighted magnetic resonance imaging findings without corresponding sensorimotor deficits
    • Wegener S, Weber R, Ramos-Cabrer P, Uhlenkueken U, Wiedermann D, Kandal K et al. Subcortical lesions after transient thread occlusion in the rat: T2-weighted magnetic resonance imaging findings without corresponding sensorimotor deficits. J Magn Reson Imaging 2005; 21: 340-346.
    • (2005) J Magn Reson Imaging , vol.21 , pp. 340-346
    • Wegener, S.1    Weber, R.2    Ramos-Cabrer, P.3    Uhlenkueken, U.4    Wiedermann, D.5    Kandal, K.6
  • 48
    • 33747180092 scopus 로고    scopus 로고
    • Modification of the method of thread manufacture improves stroke induction rate and reduces mortality after thread-occlusion of the middle cerebral artery in young or aged rats
    • Spratt NJ, Fernandez J, Chen M, Rewell S, Cox S, van Raay L et al. Modification of the method of thread manufacture improves stroke induction rate and reduces mortality after thread-occlusion of the middle cerebral artery in young or aged rats. J Neurosci Methods 2006; 155: 285-290.
    • (2006) J Neurosci Methods , vol.155 , pp. 285-290
    • Spratt, N.J.1    Fernandez, J.2    Chen, M.3    Rewell, S.4    Cox, S.5    Van Raay, L.6
  • 49
    • 33749013358 scopus 로고    scopus 로고
    • Differential recovery of multimodal MRI and behavior after transient focal cerebral ischemia in rats
    • Sicard KM, Henninger N, Fisher M, Duong TQ, Ferris CF. Differential recovery of multimodal MRI and behavior after transient focal cerebral ischemia in rats. J Cereb Blood Flow Metab 2006; 26: 1451-1462.
    • (2006) J Cereb Blood Flow Metab , vol.26 , pp. 1451-1462
    • Sicard, K.M.1    Henninger, N.2    Fisher, M.3    Duong, T.Q.4    Ferris, C.F.5
  • 50
    • 0026508278 scopus 로고
    • A new model of temporary focal neocortical ischemia in the rat
    • Buchan AM, Xue D, Slivka A. A new model of temporary focal neocortical ischemia in the rat. Stroke 1992; 23: 273-279.
    • (1992) Stroke , vol.23 , pp. 273-279
    • Buchan, A.M.1    Xue, D.2    Slivka, A.3
  • 51
    • 0025913062 scopus 로고
    • Temporal thresholds for neocortical infarction in rats subjected to reversible focal cerebral ischemia
    • Kaplan B, Brint S, Tanabe J, Jacewicz M, Wang XJ, Pulsinelli W. Temporal thresholds for neocortical infarction in rats subjected to reversible focal cerebral ischemia. Stroke 1991; 22: 1032-1039.
    • (1991) Stroke , vol.22 , pp. 1032-1039
    • Kaplan, B.1    Brint, S.2    Tanabe, J.3    Jacewicz, M.4    Wang, X.J.5    Pulsinelli, W.6
  • 52
    • 70349971747 scopus 로고    scopus 로고
    • Mapping selective neuronal loss and microglial activation in the salvaged neocortical penumbra in the rat
    • Hughes JL, Beech JS, Jones PS, Wang D, Menon DK, Baron JC. Mapping selective neuronal loss and microglial activation in the salvaged neocortical penumbra in the rat. Neuroimage 2010; 49: 19-31.
    • (2010) Neuroimage , vol.49 , pp. 19-31
    • Hughes, J.L.1    Beech, J.S.2    Jones, P.S.3    Wang, D.4    Menon, D.K.5    Baron, J.C.6
  • 53
    • 84891834400 scopus 로고    scopus 로고
    • Development of a MCA occlusion rodent model of pure cortical selective neuronal loss: Neuropathological validation. XXVIth International Conference on Cerebral Blood Flow
    • Shanghai
    • Ejaz S, Williamson D.J, Jensen-Kondering U, Ahmed T, Sawiak S.J, Baron JC. Development of a MCA occlusion rodent model of pure cortical selective neuronal loss: neuropathological validation. XXVIth International Conference on Cerebral Blood Flow, Metabolism and Brain Function. Shanghai, 2013.
    • (2013) Metabolism and Brain Function
    • Ejaz, S.1    Williamson, D.J.2    Jensen-Kondering, U.3    Ahmed, T.4    Sawiak, S.J.5    Baron, J.C.6
  • 55
  • 56
    • 61649086903 scopus 로고    scopus 로고
    • TTC, fluoro-jade b and NeuN staining confirm evolving phases of infarction induced by middle cerebral artery occlusion
    • Liu F, Schafer DP, Mc Cullough LD. TTC, fluoro-jade b and NeuN staining confirm evolving phases of infarction induced by middle cerebral artery occlusion. J Neurosci Methods 2009; 179: 1-8.
    • (2009) J Neurosci Methods , vol.179 , pp. 1-8
    • Liu, F.1    Schafer, D.P.2    Mc Cullough, L.D.3
  • 57
    • 0023199154 scopus 로고
    • Neuronal injury in the infarct border: A neuropathological study in the rat
    • Nedergaard M. Neuronal injury in the infarct border: a neuropathological study in the rat. Acta Neuropathol 1987; 73: 267-274.
    • (1987) Acta Neuropathol , vol.73 , pp. 267-274
    • Nedergaard, M.1
  • 59
    • 10744220365 scopus 로고    scopus 로고
    • Magnetic resonance imaging shows delayed ischemic striatal neurodegeneration
    • Fujioka M, Taoka T, Matsuo Y, Mishima K, Ogoshi K, Kondo Y et al. Magnetic resonance imaging shows delayed ischemic striatal neurodegeneration. Ann Neurol 2003; 54: 732-747.
    • (2003) Ann Neurol , vol.54 , pp. 732-747
    • Fujioka, M.1    Taoka, T.2    Matsuo, Y.3    Mishima, K.4    Ogoshi, K.5    Kondo, Y.6
  • 60
    • 0020695009 scopus 로고
    • Flow and neuronal density in tissue surrounding chronic infarction
    • Mies G, Auer LM, Ebhardt G, Traupe H, Heiss WD. Flow and neuronal density in tissue surrounding chronic infarction. Stroke 1983; 14: 22-27.
    • (1983) Stroke , vol.14 , pp. 22-27
    • Mies, G.1    Auer, L.M.2    Ebhardt, G.3    Traupe, H.4    Heiss, W.D.5
  • 61
    • 0022899052 scopus 로고
    • Cell density in the border zone around old small human brain infarcts
    • Nedergaard M, Vorstrup S, Astrup J. Cell density in the border zone around old small human brain infarcts. Stroke 1986; 17: 1129-1137.
    • (1986) Stroke , vol.17 , pp. 1129-1137
    • Nedergaard, M.1    Vorstrup, S.2    Astrup, J.3
  • 62
    • 0023032869 scopus 로고
    • Is there a transitional zone between brain infarcts and the surrounding brain? A histological study
    • Torvik A, Svindland A. Is there a transitional zone between brain infarcts and the surrounding brain? A histological study. Acta Neurol Scand 1986; 74: 365-370.
    • (1986) Acta Neurol Scand , vol.74 , pp. 365-370
    • Torvik, A.1    Svindland, A.2
  • 63
    • 0021721978 scopus 로고
    • Cell density and cortex thickness in the border zone surrounding old infarcts in the human brain
    • Nedergaard M, Astrup J, Klinken L. Cell density and cortex thickness in the border zone surrounding old infarcts in the human brain. Stroke 1984; 15: 1033-1039.
    • (1984) Stroke , vol.15 , pp. 1033-1039
    • Nedergaard, M.1    Astrup, J.2    Klinken, L.3
  • 64
    • 0026582547 scopus 로고
    • Central benzodiazepine receptors in human brain: Estimation of regional BMAX and KD values with positron emission tomography
    • Abadie P, Baron JC, Bisserbe JC, Boulenger JP, Rioux P, Travere JM et al. Central benzodiazepine receptors in human brain: estimation of regional BMAX and KD values with positron emission tomography. Eur J Pharmacol 1992; 213: 107-115.
    • (1992) Eur J Pharmacol , vol.213 , pp. 107-115
    • Abadie, P.1    Baron, J.C.2    Bisserbe, J.C.3    Boulenger, J.P.4    Rioux, P.5    Travere, J.M.6
  • 65
    • 0023925694 scopus 로고
    • Regional specific binding of [11c]ro 15 1788 to central type benzodiazepine receptors in human brain: Quantitative evaluation by pet
    • Pappata S, Samson Y, Chavoix C, Prenant C, Maziere M, Baron JC. Regional specific binding of [11c]ro 15 1788 to central type benzodiazepine receptors in human brain: quantitative evaluation by pet. J Cereb Blood Flow Metab 1988; 8: 304-313.
    • (1988) J Cereb Blood Flow Metab , vol.8 , pp. 304-313
    • Pappata, S.1    Samson, Y.2    Chavoix, C.3    Prenant, C.4    Maziere, M.5    Baron, J.C.6
  • 66
    • 0027515749 scopus 로고
    • Benzo-diazepine receptor equilibrium constants for flumazenil and midazolam determined in humans with the single photon emission computer tomography tracer [123i]iomazenil
    • Videbaek C, Friberg L, Holm S, Wammen S, Foged C, Andersen JV et al. Benzo-diazepine receptor equilibrium constants for flumazenil and midazolam determined in humans with the single photon emission computer tomography tracer [123i]iomazenil. Eur J Pharmacol 1993; 249: 43-51.
    • (1993) Eur J Pharmacol , vol.249 , pp. 43-51
    • Videbaek, C.1    Friberg, L.2    Holm, S.3    Wammen, S.4    Foged, C.5    Andersen, J.V.6
  • 67
    • 0034028551 scopus 로고    scopus 로고
    • Detection of viable cortical neurons using benzodiazepine receptor imaging after reversible focal ischaemia in rats: Comparison with regional cerebral blood flow
    • Watanabe Y, Nakano T, Yutani K, Nishimura H, Kusuoka H, Nakamura H et al. Detection of viable cortical neurons using benzodiazepine receptor imaging after reversible focal ischaemia in rats: comparison with regional cerebral blood flow. Eur J Nucl Med 2000; 27: 308-313.
    • (2000) Eur J Nucl Med , vol.27 , pp. 308-313
    • Watanabe, Y.1    Nakano, T.2    Yutani, K.3    Nishimura, H.4    Kusuoka, H.5    Nakamura, H.6
  • 68
    • 0031017130 scopus 로고    scopus 로고
    • Incomplete brain infarction of reperfused cortex may be quantitated with iomazenil
    • Nakagawara J, Sperling B, Lassen NA. Incomplete brain infarction of reperfused cortex may be quantitated with iomazenil. Stroke 1997; 28: 124-132.
    • (1997) Stroke , vol.28 , pp. 124-132
    • Nakagawara, J.1    Sperling, B.2    Lassen, N.A.3
  • 69
    • 3843059189 scopus 로고    scopus 로고
    • Discrepancy between cell injury and benzodiazepine receptor binding after transient middle cerebral artery occlusion in rats
    • Abe K, Kashiwagi Y, Tokumura M, Hosoi R, Hatazawa J, Inoue O. Discrepancy between cell injury and benzodiazepine receptor binding after transient middle cerebral artery occlusion in rats. Synapse 2004; 53: 234-239.
    • (2004) Synapse , vol.53 , pp. 234-239
    • Abe, K.1    Kashiwagi, Y.2    Tokumura, M.3    Hosoi, R.4    Hatazawa, J.5    Inoue, O.6
  • 70
    • 78650641650 scopus 로고    scopus 로고
    • Multiparametric assessment of acute and subacute ischemic neuronal damage: A small animal positron emission tomography study with rat photochemically induced thrombosis model
    • Fukumoto D, Hosoya T, Nishiyama S, Harada N, Iwata H, Yamamoto S et al. Multiparametric assessment of acute and subacute ischemic neuronal damage: a small animal positron emission tomography study with rat photochemically induced thrombosis model. Synapse 2011; 65: 207-214.
    • (2011) Synapse , vol.65 , pp. 207-214
    • Fukumoto, D.1    Hosoya, T.2    Nishiyama, S.3    Harada, N.4    Iwata, H.5    Yamamoto, S.6
  • 71
    • 79955464540 scopus 로고    scopus 로고
    • Positron emission tomography with 11c-flumazenil in the rat shows preservation of binding sites during the acute phase after 2 h-transient focal ischemia
    • Rojas S, Martin A, Pareto D, Herance JR, Abad S, Ruiz A et al. Positron emission tomography with 11c-flumazenil in the rat shows preservation of binding sites during the acute phase after 2 h-transient focal ischemia. Neuroscience 2011; 182: 208-216.
    • (2011) Neuroscience , vol.182 , pp. 208-216
    • Rojas, S.1    Martin, A.2    Pareto, D.3    Herance, J.R.4    Abad, S.5    Ruiz, A.6
  • 72
    • 0027070539 scopus 로고
    • Electron microscopic investigation of the cerebral cortex after cerebral ischemia and reperfusion in the gerbil
    • Tomimoto H, Yanagihara T. Electron microscopic investigation of the cerebral cortex after cerebral ischemia and reperfusion in the gerbil. Brain Res 1992; 598: 87-97.
    • (1992) Brain Res , vol.598 , pp. 87-97
    • Tomimoto, H.1    Yanagihara, T.2
  • 73
    • 20044374010 scopus 로고    scopus 로고
    • Rapid reversible changes in dendritic spine structure in vivo gated by the degree of ischemia
    • Zhang S, Boyd J, Delaney K, Murphy TH. Rapid reversible changes in dendritic spine structure in vivo gated by the degree of ischemia. J Neurosci 2005; 25: 5333-5338.
    • (2005) J Neurosci , vol.25 , pp. 5333-5338
    • Zhang, S.1    Boyd, J.2    Delaney, K.3    Murphy, T.H.4
  • 74
    • 0030880667 scopus 로고    scopus 로고
    • Assessment of benzodiazepine receptors using iodine-123-labeled iomazenil single-photon emission computed tomography in patients with ischemic cere-brovascular disease. A comparison with PET study
    • Dong Y, Fukuyama H, Nabatame H, Yamauchi H, Shibasaki H, Yonekura Y. Assessment of benzodiazepine receptors using iodine-123-labeled iomazenil single-photon emission computed tomography in patients with ischemic cere-brovascular disease. A comparison with PET study. Stroke 1997; 28: 1776-1782.
    • (1997) Stroke , vol.28 , pp. 1776-1782
    • Dong, Y.1    Fukuyama, H.2    Nabatame, H.3    Yamauchi, H.4    Shibasaki, H.5    Yonekura, Y.6
  • 76
    • 0030667356 scopus 로고    scopus 로고
    • Benzodiaze-pine receptors in chronic cerebrovascular disease: Comparison with blood flow and metabolism
    • Sasaki M, Ichiya Y, Kuwabara Y, Yoshida T, Fukumura T, Masuda K. Benzodiaze-pine receptors in chronic cerebrovascular disease: comparison with blood flow and metabolism. J Nucl Med 1997; 38: 1693-1698.
    • (1997) J Nucl Med , vol.38 , pp. 1693-1698
    • Sasaki, M.1    Ichiya, Y.2    Kuwabara, Y.3    Yoshida, T.4    Fukumura, T.5    Masuda, K.6
  • 77
    • 0030779269 scopus 로고    scopus 로고
    • Mechanism of reduction of cortical blood flow in striatocapsular infarction: Studies using [123i]iomazenil spect
    • Takahashi W, Ohnuki Y, Ohta T, Hamano H, Yamamoto M, Shinohara Y. Mechanism of reduction of cortical blood flow in striatocapsular infarction: studies using [123i]iomazenil spect. Neuroimage 1997; 6: 75-80.
    • (1997) Neuroimage , vol.6 , pp. 75-80
    • Takahashi, W.1    Ohnuki, Y.2    Ohta, T.3    Hamano, H.4    Yamamoto, M.5    Shinohara, Y.6
  • 78
    • 33750948090 scopus 로고    scopus 로고
    • Iomazenil-single-photon emission computed tomography reveals selective neuronal loss in magnetic resonance-defined mismatch areas
    • Saur D, Buchert R, Knab R, Weiller C, Rother J. Iomazenil-single-photon emission computed tomography reveals selective neuronal loss in magnetic resonance-defined mismatch areas. Stroke 2006; 37: 2713-2719.
    • (2006) Stroke , vol.37 , pp. 2713-2719
    • Saur, D.1    Buchert, R.2    Knab, R.3    Weiller, C.4    Rother, J.5
  • 79
    • 54949110630 scopus 로고    scopus 로고
    • Selective neuronal loss in rescued penumbra relates to initial hypoperfusion
    • Guadagno JV, Jones PS, Aigbirhio FI, Wang D, Fryer TD, Day DJ et al. Selective neuronal loss in rescued penumbra relates to initial hypoperfusion. Brain 2008; 131: 2666-2678.
    • (2008) Brain , vol.131 , pp. 2666-2678
    • Guadagno, J.V.1    Jones, P.S.2    Aigbirhio, F.I.3    Wang, D.4    Fryer, T.D.5    Day, D.J.6
  • 80
    • 84878830382 scopus 로고    scopus 로고
    • Is neural activation within the rescued penumbra impeded by selective neuronal loss?
    • Carrera E, Jones PS, Morris RS, Alawneh J, Hong YT, Aigbirhio FI et al. Is neural activation within the rescued penumbra impeded by selective neuronal loss? Brain 2013; 136: 1816-1829.
    • (2013) Brain , vol.136 , pp. 1816-1829
    • Carrera, E.1    Jones, P.S.2    Morris, R.S.3    Alawneh, J.4    Hong, Y.T.5    Aigbirhio, F.I.6
  • 81
    • 0032935852 scopus 로고    scopus 로고
    • Delayed ischemic hyperintensity on t1-weighted MRI in the caudoputamen and cerebral cortex of humans after spectacular shrinking deficit
    • Fujioka M, Taoka T, Hiramatsu KI, Sakaguchi S, Sakaki T. Delayed ischemic hyperintensity on t1-weighted MRI in the caudoputamen and cerebral cortex of humans after spectacular shrinking deficit. Stroke 1999; 30: 1038-1042.
    • (1999) Stroke , vol.30 , pp. 1038-1042
    • Fujioka, M.1    Taoka, T.2    Hiramatsu, K.I.3    Sakaguchi, S.4    Sakaki, T.5
  • 82
    • 33748369466 scopus 로고    scopus 로고
    • Delayed changes in T1-weighted signal intensity in a rat model of 15-minute transient focal ischemia studied by magnetic resonance imaging/spectroscopy and synchrotron radiation X-ray fluorescence
    • Wang X, Qian J, He R, Wei L, Liu N, Zhang Z et al. Delayed changes in T1-weighted signal intensity in a rat model of 15-minute transient focal ischemia studied by magnetic resonance imaging/spectroscopy and synchrotron radiation X-ray fluorescence. Magn Reson Med 2006; 56: 474-480.
    • (2006) Magn Reson Med , vol.56 , pp. 474-480
    • Wang, X.1    Qian, J.2    He, R.3    Wei, L.4    Liu, N.5    Zhang, Z.6
  • 83
    • 0036141115 scopus 로고    scopus 로고
    • Severe ADC decreases do not predict irreversible tissue damage in humans
    • Fiehler J, Foth M, Kucinski T, Knab R, von Bezold M, Weiller C et al. Severe ADC decreases do not predict irreversible tissue damage in humans. Stroke 2002; 33: 79-86.
    • (2002) Stroke , vol.33 , pp. 79-86
    • Fiehler, J.1    Foth, M.2    Kucinski, T.3    Knab, R.4    Von Bezold, M.5    Weiller, C.6
  • 84
    • 0034117736 scopus 로고    scopus 로고
    • Thrombolytic reversal of acute human cerebral ischemic injury shown by dif-fusion/perfusion magnetic resonance imaging
    • Kidwell CS, Saver JL, Mattiello J, Starkman S, Vinuela F, Duckwiler G et al. Thrombolytic reversal of acute human cerebral ischemic injury shown by dif-fusion/perfusion magnetic resonance imaging. Ann Neurol 2000; 47: 462-469.
    • (2000) Ann Neurol , vol.47 , pp. 462-469
    • Kidwell, C.S.1    Saver, J.L.2    Mattiello, J.3    Starkman, S.4    Vinuela, F.5    Duckwiler, G.6
  • 85
    • 0036895552 scopus 로고    scopus 로고
    • Late secondary ischemic injury in patients receiving intraarterial thrombolysis
    • Kidwell CS, Saver JL, Starkman S, Duckwiler G, Jahan R, Vespa P et al. Late secondary ischemic injury in patients receiving intraarterial thrombolysis. Ann Neurol 2002; 52: 698-703.
    • (2002) Ann Neurol , vol.52 , pp. 698-703
    • Kidwell, C.S.1    Saver, J.L.2    Starkman, S.3    Duckwiler, G.4    Jahan, R.5    Vespa, P.6
  • 86
    • 0029814808 scopus 로고    scopus 로고
    • Spontaneous neurological recovery after stroke and the fate of the ischemic penumbra
    • Furlan M, Marchal G, Viader F, Derlon JM, Baron JC. Spontaneous neurological recovery after stroke and the fate of the ischemic penumbra. Ann Neurol 1996; 40: 216-226.
    • (1996) Ann Neurol , vol.40 , pp. 216-226
    • Furlan, M.1    Marchal, G.2    Viader, F.3    Derlon, J.M.4    Baron, J.C.5
  • 89
    • 18744390510 scopus 로고    scopus 로고
    • Vicarious function within the human primary motor cortex? A longitudinal fmri stroke study
    • Jaillard A, Martin CD, Garambois K, Lebas JF, Hommel M. Vicarious function within the human primary motor cortex? A longitudinal fmri stroke study. Brain 2005; 128: 1122-1138.
    • (2005) Brain , vol.128 , pp. 1122-1138
    • Jaillard, A.1    Martin, C.D.2    Garambois, K.3    Lebas, J.F.4    Hommel, M.5
  • 90
    • 34047121167 scopus 로고    scopus 로고
    • Multi-modal characterization of the neocortical clip model of focal cerebral ischaemia by MRI, behaviour and immunohistochemistry
    • Ashioti M, Beech JS, Lowe AS, Hesselink MB, Modo M, Williams SC. Multi-modal characterization of the neocortical clip model of focal cerebral ischaemia by MRI, behaviour and immunohistochemistry. Brain Res 2007; 1145: 177-189.
    • (2007) Brain Res , vol.1145 , pp. 177-189
    • Ashioti, M.1    Beech, J.S.2    Lowe, A.S.3    Hesselink, M.B.4    Modo, M.5    Williams, S.C.6
  • 91
    • 84872809579 scopus 로고    scopus 로고
    • Characterization of long-term functional outcome in a murine model of mild brain ischemia
    • Balkaya M, Krober J, Gertz K, Peruzzaro S, Endres M. Characterization of long-term functional outcome in a murine model of mild brain ischemia. J Neurosci Methods 2013; 213: 179-187.
    • (2013) J Neurosci Methods , vol.213 , pp. 179-187
    • Balkaya, M.1    Krober, J.2    Gertz, K.3    Peruzzaro, S.4    Endres, M.5
  • 92
  • 93
    • 0347986834 scopus 로고    scopus 로고
    • Dysexecutive syndrome after mild cerebral ischemia? Mice learn normally but have deficits in strategy switching
    • Winter B, Bert B, Fink H, Dirnagl U, Endres M. Dysexecutive syndrome after mild cerebral ischemia? Mice learn normally but have deficits in strategy switching. Stroke 2004; 35: 191-195.
    • (2004) Stroke , vol.35 , pp. 191-195
    • Winter, B.1    Bert, B.2    Fink, H.3    Dirnagl, U.4    Endres, M.5
  • 94
    • 35648934983 scopus 로고    scopus 로고
    • Identification of alzheimer and vascular lesion thresholds for mixed dementia
    • Gold G, Giannakopoulos P, Herrmann FR, Bouras C, Kovari E. Identification of alzheimer and vascular lesion thresholds for mixed dementia. Brain 2007; 130: 2830-2836.
    • (2007) Brain , vol.130 , pp. 2830-2836
    • Gold, G.1    Giannakopoulos, P.2    Herrmann, F.R.3    Bouras, C.4    Kovari, E.5
  • 95
    • 84872093859 scopus 로고    scopus 로고
    • Telephone assessment of cognition after transient ischemic attack and stroke: Modified telephone interview of cognitive status and telephone Montreal cognitive assessment versus face-to-face Montreal cognitive assessment and neuropsychological battery
    • Pendlebury ST, Welch SJ, Cuthbertson FC, Mariz J, Mehta Z, Rothwell PM. Telephone assessment of cognition after transient ischemic attack and stroke: modified telephone interview of cognitive status and telephone Montreal cognitive assessment versus face-to-face Montreal cognitive assessment and neuropsychological battery. Stroke 2012; 44: 227-229.
    • (2012) Stroke , vol.44 , pp. 227-229
    • Pendlebury, S.T.1    Welch, S.J.2    Cuthbertson, F.C.3    Mariz, J.4    Mehta, Z.5    Rothwell, P.M.6
  • 97
    • 0026608454 scopus 로고
    • The CBF threshold and dynamics for focal cerebral infarction in spontaneously hypertensive rats
    • Jacewicz M, Tanabe J, Pulsinelli WA. The CBF threshold and dynamics for focal cerebral infarction in spontaneously hypertensive rats. J Cereb Blood Flow Metab 1992; 12: 359-370.
    • (1992) J Cereb Blood Flow Metab , vol.12 , pp. 359-370
    • Jacewicz, M.1    Tanabe, J.2    Pulsinelli, W.A.3
  • 99
    • 28044434413 scopus 로고    scopus 로고
    • Nestin-expressing cells divide and adopt a complex electrophysiologic phenotype after transient brain ischemia
    • Kronenberg G, Wang LP, Synowitz M, Gertz K, Katchanov J, Glass R et al. Nestin-expressing cells divide and adopt a complex electrophysiologic phenotype after transient brain ischemia. J Cereb Blood Flow Metab 2005; 25: 1613-1624.
    • (2005) J Cereb Blood Flow Metab , vol.25 , pp. 1613-1624
    • Kronenberg, G.1    Wang, L.P.2    Synowitz, M.3    Gertz, K.4    Katchanov, J.5    Glass, R.6
  • 100
    • 51349124043 scopus 로고    scopus 로고
    • Mild brain ischemia induces unique physiological properties in striatal astrocytes
    • Wang LP, Cheung G, Kronenberg G, Gertz K, Ji S, Kempermann G et al. Mild brain ischemia induces unique physiological properties in striatal astrocytes. Glia 2008; 56: 925-934.
    • (2008) Glia , vol.56 , pp. 925-934
    • Wang, L.P.1    Cheung, G.2    Kronenberg, G.3    Gertz, K.4    Ji, S.5    Kempermann, G.6
  • 101
    • 84855461934 scopus 로고    scopus 로고
    • A micropet study of the regional distribution of [(11)c]-pk11195 binding following temporary focal cerebral ischemia in the rat. Correlation with postmortem mapping of microglia activation
    • Hughes JL, Jones PS, Beech JS, Wang D, Menon DK, Aigbirhio FI et al. A micropet study of the regional distribution of [(11)c]-pk11195 binding following temporary focal cerebral ischemia in the rat. Correlation with postmortem mapping of microglia activation. Neuroimage 2012; 59: 2007-2016.
    • (2012) Neuroimage , vol.59 , pp. 2007-2016
    • Hughes, J.L.1    Jones, P.S.2    Beech, J.S.3    Wang, D.4    Menon, D.K.5    Aigbirhio, F.I.6
  • 102
    • 64549119716 scopus 로고    scopus 로고
    • Inflammation, plasticity and real-time imaging after cerebral ischemia
    • Kriz J, Lalancette-Hebert M. Inflammation, plasticity and real-time imaging after cerebral ischemia. Acta Neuropathol 2009; 117: 497-509.
    • (2009) Acta Neuropathol , vol.117 , pp. 497-509
    • Kriz, J.1    Lalancette-Hebert, M.2
  • 103
    • 84868209611 scopus 로고    scopus 로고
    • Microglia/macrophage polarization dynamics reveal novel mechanism of injury expansion after focal cerebral ischemia
    • Hu X, Li P, Guo Y, Wang H, Leak RK, Chen S et al. Microglia/macrophage polarization dynamics reveal novel mechanism of injury expansion after focal cerebral ischemia. Stroke 2012; 43: 3063-3070.
    • (2012) Stroke , vol.43 , pp. 3063-3070
    • Hu, X.1    Li, P.2    Guo, Y.3    Wang, H.4    Leak, R.K.5    Chen, S.6
  • 104
    • 33750923721 scopus 로고    scopus 로고
    • Physical activity improves long-term stroke outcome via endothelial nitric oxide synthase-dependent augmentation of neovascularization and cerebral blood flow
    • Gertz K, Priller J, Kronenberg G, Fink KB, Winter B, Schrock H et al. Physical activity improves long-term stroke outcome via endothelial nitric oxide synthase-dependent augmentation of neovascularization and cerebral blood flow. Circ Res 2006; 99: 1132-1140.
    • (2006) Circ Res , vol.99 , pp. 1132-1140
    • Gertz, K.1    Priller, J.2    Kronenberg, G.3    Fink, K.B.4    Winter, B.5    Schrock, H.6
  • 106
  • 107
    • 0031718374 scopus 로고    scopus 로고
    • Prolonged therapeutic window for ischemic brain damage caused by delayed caspase activation
    • Fink K, Zhu J, Namura S, Shimizu-Sasamata M, Endres M, Ma J et al. Prolonged therapeutic window for ischemic brain damage caused by delayed caspase activation. J Cereb Blood Flow Metab 1998; 18: 1071-1076.
    • (1998) J Cereb Blood Flow Metab , vol.18 , pp. 1071-1076
    • Fink, K.1    Zhu, J.2    Namura, S.3    Shimizu-Sasamata, M.4    Endres, M.5    Ma, J.6
  • 108
    • 0032525260 scopus 로고    scopus 로고
    • Activation and cleavage of caspase-3 in apoptosis induced by experimental cerebral ischemia
    • Namura S, Zhu J, Fink K, Endres M, Srinivasan A, Tomaselli KJ et al. Activation and cleavage of caspase-3 in apoptosis induced by experimental cerebral ischemia. J Neurosci 1998; 18: 3659-3668.
    • (1998) J Neurosci , vol.18 , pp. 3659-3668
    • Namura, S.1    Zhu, J.2    Fink, K.3    Endres, M.4    Srinivasan, A.5    Tomaselli, K.J.6
  • 109
    • 0035879076 scopus 로고    scopus 로고
    • Mild cerebral ischemia induces loss of cyclin-dependent kinase inhibitors and activation of cell cycle machinery before delayed neuronal cell death
    • Katchanov J, Harms C, Gertz K, Hauck L, Waeber C, Hirt L et al. Mild cerebral ischemia induces loss of cyclin-dependent kinase inhibitors and activation of cell cycle machinery before delayed neuronal cell death. J Neurosci 2001; 21: 5045-5053.
    • (2001) J Neurosci , vol.21 , pp. 5045-5053
    • Katchanov, J.1    Harms, C.2    Gertz, K.3    Hauck, L.4    Waeber, C.5    Hirt, L.6
  • 110
    • 0018763304 scopus 로고
    • Local cerebral glucose metabolism during controlled hypoxemia in rats
    • Pulsinelli WA, Duffy TE. Local cerebral glucose metabolism during controlled hypoxemia in rats. Science 1979; 204: 626-629.
    • (1979) Science , vol.204 , pp. 626-629
    • Pulsinelli, W.A.1    Duffy, T.E.2
  • 112
    • 84861592073 scopus 로고    scopus 로고
    • Secondary neurodegeneration in remote regions after focal cerebral infarction: A new target for stroke management?
    • Zhang J, Zhang Y, Xing S, Liang Z, Zeng J. Secondary neurodegeneration in remote regions after focal cerebral infarction: a new target for stroke management? Stroke 2012; 43: 1700-1705.
    • (2012) Stroke , vol.43 , pp. 1700-1705
    • Zhang, J.1    Zhang, Y.2    Xing, S.3    Liang, Z.4    Zeng, J.5
  • 113
    • 1042289610 scopus 로고
    • Aphasie und diaschisis
    • von Monakow C. Aphasie und diaschisis. Neurol Centralbl 1906; 25: 1026-1038.
    • (1906) Neurol Centralbl , vol.25 , pp. 1026-1038
    • Von Monakow, C.1
  • 115
    • 84864279791 scopus 로고    scopus 로고
    • Exofocal dopami-nergic degeneration as antidepressant target in mouse model of poststroke depression
    • Kronenberg G, Balkaya M, Prinz V, Gertz K, Ji S, Kirste I et al. Exofocal dopami-nergic degeneration as antidepressant target in mouse model of poststroke depression. Biol Psychiatry 2012; 72: 273-281.
    • (2012) Biol Psychiatry , vol.72 , pp. 273-281
    • Kronenberg, G.1    Balkaya, M.2    Prinz, V.3    Gertz, K.4    Ji, S.5    Kirste, I.6
  • 116
    • 0025134004 scopus 로고
    • Atrophy of the ipsilateral substantia nigra following middle cerebral artery occlusion in the rat
    • Tamura A, Kirino T, Sano K, Takagi K, Oka H. Atrophy of the ipsilateral substantia nigra following middle cerebral artery occlusion in the rat. Brain Res 1990; 510: 154-157.
    • (1990) Brain Res , vol.510 , pp. 154-157
    • Tamura, A.1    Kirino, T.2    Sano, K.3    Takagi, K.4    Oka, H.5
  • 117
    • 0023135167 scopus 로고
    • Delayed transneuronal death of substantia nigra neurons prevented by gamma-aminobutyric acid agonist
    • Saji M, Reis DJ. Delayed transneuronal death of substantia nigra neurons prevented by gamma-aminobutyric acid agonist. Science 1987; 235: 66-69.
    • (1987) Science , vol.235 , pp. 66-69
    • Saji, M.1    Reis, D.J.2
  • 118
    • 0029279177 scopus 로고
    • Delayed histopathological neuronal damage in the substantia nigra compacta (nucleus a9) after transient forebrain ischaemia
    • Volpe BT, Blau AD, Wessel TC, Saji M. Delayed histopathological neuronal damage in the substantia nigra compacta (nucleus a9) after transient forebrain ischaemia. Neurobiol Dis 1995; 2: 119-127.
    • (1995) Neurobiol Dis , vol.2 , pp. 119-127
    • Volpe, B.T.1    Blau, A.D.2    Wessel, T.C.3    Saji, M.4
  • 119
    • 0031461307 scopus 로고    scopus 로고
    • Striatal infarction in the rat causes a transient reduction of tyrosine hydroxylase immunoreactivity in the ipsilateral substantia nigra
    • Soriano MA, Justicia C, Ferrer I, Rodriguez-Farre E, Planas AM. Striatal infarction in the rat causes a transient reduction of tyrosine hydroxylase immunoreactivity in the ipsilateral substantia nigra. Neurobiol Dis 1997; 4: 376-385.
    • (1997) Neurobiol Dis , vol.4 , pp. 376-385
    • Soriano, M.A.1    Justicia, C.2    Ferrer, I.3    Rodriguez-Farre, E.4    Planas, A.M.5
  • 120
    • 80051513901 scopus 로고    scopus 로고
    • Activation of cerebral peroxisome proliferator-activated receptors gamma (ppargamma) reduces neuronal damage in the substantia nigra after transient focal cerebral ischaemia in the rat
    • Zuhayra M, Zhao Y, von Forstner C, Henze E, Gohlke P, Culman J et al. Activation of cerebral peroxisome proliferator-activated receptors gamma (ppargamma) reduces neuronal damage in the substantia nigra after transient focal cerebral ischaemia in the rat. Neuropathol Appl Neurobiol 2011; 37: 738-752.
    • (2011) Neuropathol Appl Neurobiol , vol.37 , pp. 738-752
    • Zuhayra, M.1    Zhao, Y.2    Von Forstner, C.3    Henze, E.4    Gohlke, P.5    Culman, J.6
  • 121
    • 0027286473 scopus 로고
    • Delayed histologic damage and neuron death in the substantia nigra reticulata following transient forebrain ischemia depends on the extent of initial striatal injury
    • Saji M, Volpe BT. Delayed histologic damage and neuron death in the substantia nigra reticulata following transient forebrain ischemia depends on the extent of initial striatal injury. Neurosci Lett 1993; 155: 47-50.
    • (1993) Neurosci Lett , vol.155 , pp. 47-50
    • Saji, M.1    Volpe, B.T.2
  • 122
    • 34948907309 scopus 로고    scopus 로고
    • Long-term alterations in MU, delta and kappa opioidergic receptors following middle cerebral artery occlusion in mice
    • Boutin H, Catherine A, Mackenzie ET, Jauzac P, Dauphin F. Long-term alterations in MU, delta and kappa opioidergic receptors following middle cerebral artery occlusion in mice. Acta Neuropathol 2007; 114: 491-500.
    • (2007) Acta Neuropathol , vol.114 , pp. 491-500
    • Boutin, H.1    Catherine, A.2    Mackenzie, E.T.3    Jauzac, P.4    Dauphin, F.5
  • 123
    • 0030566729 scopus 로고    scopus 로고
    • Neuroprotective effects of the dopamine d2/d3 agonist pramipexole against postischemic or methamphetamine-induced degeneration of nigrostriatal neurons
    • Hall ED, Andrus PK, Oostveen JA, Althaus JS, VonVoigtlander PF. Neuroprotective effects of the dopamine d2/d3 agonist pramipexole against postischemic or methamphetamine-induced degeneration of nigrostriatal neurons. Brain Res 1996; 742: 80-88.
    • (1996) Brain Res , vol.742 , pp. 80-88
    • Hall, E.D.1    Andrus, P.K.2    Oostveen, J.A.3    Althaus, J.S.4    Vonvoigtlander, P.F.5
  • 124
    • 34547659257 scopus 로고    scopus 로고
    • Neuroi-maging and histopathological evaluation of delayed neurological damage produced by artificial occlusion of the middle cerebral artery in cynomolgus monkeys: Establishment of a monkey model for delayed cerebral ischemia
    • Hirouchi Y, Suzuki E, Mitsuoka C, Jin H, Kitajima S, Kohjimoto Y et al. Neuroi-maging and histopathological evaluation of delayed neurological damage produced by artificial occlusion of the middle cerebral artery in cynomolgus monkeys: establishment of a monkey model for delayed cerebral ischemia. Exp Toxicol Pathol 2007; 59: 9-16.
    • (2007) Exp Toxicol Pathol , vol.59 , pp. 9-16
    • Hirouchi, Y.1    Suzuki, E.2    Mitsuoka, C.3    Jin, H.4    Kitajima, S.5    Kohjimoto, Y.6
  • 125
    • 0021041430 scopus 로고
    • Reaction of the substantia nigra to massive basal ganglia infarction
    • Forno LS. Reaction of the substantia nigra to massive basal ganglia infarction. Acta Neuropathol 1983; 62: 96-102.
    • (1983) Acta Neuropathol , vol.62 , pp. 96-102
    • Forno, L.S.1
  • 126
    • 0024947317 scopus 로고
    • Secondary degeneration of substantia nigra following massive basal ganglia infarction
    • Ohara S, Kondo K, Kagoshima M, Yanagisawa N. [secondary degeneration of substantia nigra following massive basal ganglia infarction]. Rinsho Shinkeigaku 1989; 29: 1352-1356.
    • (1989) Rinsho Shinkeigaku , vol.29 , pp. 1352-1356
    • Ohara, S.1    Kondo, K.2    Kagoshima, M.3    Yanagisawa, N.4
  • 127
    • 0035052530 scopus 로고    scopus 로고
    • Astrocytic swelling in the ipsilateral substantia nigra after occlusion of the middle cerebral artery in rats
    • Nakane M, Tamura A, Miyasaka N, Nagaoka T, Kuroiwa T. Astrocytic swelling in the ipsilateral substantia nigra after occlusion of the middle cerebral artery in rats. AJNR Am J Neuroradiol 2001; 22: 660-663.
    • (2001) AJNR Am J Neuroradiol , vol.22 , pp. 660-663
    • Nakane, M.1    Tamura, A.2    Miyasaka, N.3    Nagaoka, T.4    Kuroiwa, T.5
  • 128
    • 0030756467 scopus 로고    scopus 로고
    • Degeneration of the ipsilateral substantia nigra after striatal infarction: Evaluation with MR imaging
    • Ogawa T, Okudera T, Inugami A, Noguchi K, Kado H, Yoshida Y et al. Degeneration of the ipsilateral substantia nigra after striatal infarction: evaluation with MR imaging. Radiology 1997; 204: 847-851.
    • (1997) Radiology , vol.204 , pp. 847-851
    • Ogawa, T.1    Okudera, T.2    Inugami, A.3    Noguchi, K.4    Kado, H.5    Yoshida, Y.6
  • 129
    • 33745080965 scopus 로고    scopus 로고
    • Increased thalamic neurodegeneration following ischaemic cortical stroke in osteopontin-deficient mice
    • Schroeter M, Zickler P, Denhardt DT, Hartung HP, Jander S. Increased thalamic neurodegeneration following ischaemic cortical stroke in osteopontin-deficient mice. Brain 2006; 129: 1426-1437.
    • (2006) Brain , vol.129 , pp. 1426-1437
    • Schroeter, M.1    Zickler, P.2    Denhardt, D.T.3    Hartung, H.P.4    Jander, S.5
  • 130
    • 0025838155 scopus 로고
    • Thalamic atrophy following cerebral infarction in the territory of the middle cerebral artery
    • Tamura A, Tahira Y, Nagashima H, Kirino T, Gotoh O, Hojo S et al. Thalamic atrophy following cerebral infarction in the territory of the middle cerebral artery. Stroke 1991; 22: 615-618.
    • (1991) Stroke , vol.22 , pp. 615-618
    • Tamura, A.1    Tahira, Y.2    Nagashima, H.3    Kirino, T.4    Gotoh, O.5    Hojo, S.6
  • 131
    • 0026525979 scopus 로고
    • Degeneration of the ipsilateral substantia nigra following cerebral infarction in the striatum
    • Nakane M, Teraoka A, Asato R, Tamura A. Degeneration of the ipsilateral substantia nigra following cerebral infarction in the striatum. Stroke 1992; 23: 328-332.
    • (1992) Stroke , vol.23 , pp. 328-332
    • Nakane, M.1    Teraoka, A.2    Asato, R.3    Tamura, A.4
  • 132
    • 0018132248 scopus 로고
    • Topographical organization of the striatonigral pathway revealed by anterograde and retrograde neuroanatomical tracing techniques
    • Tulloch IF, Arbuthnott GW, Wright AK. Topographical organization of the striatonigral pathway revealed by anterograde and retrograde neuroanatomical tracing techniques. J Anat 1978; 127: 425-441.
    • (1978) J Anat , vol.127 , pp. 425-441
    • Tulloch, I.F.1    Arbuthnott, G.W.2    Wright, A.K.3
  • 133
    • 0025598059 scopus 로고
    • Time-sequential change of amino acid neurotransmitters-gaba, aspartate and glutamate-in the rat basal ganglia following middle cerebral artery occlusion
    • Nakayama H, Tamura A, Kanazawa I, Sano K. Time-sequential change of amino acid neurotransmitters-gaba, aspartate and glutamate-in the rat basal ganglia following middle cerebral artery occlusion. Neurol Res 1990; 12: 231-235.
    • (1990) Neurol Res , vol.12 , pp. 231-235
    • Nakayama, H.1    Tamura, A.2    Kanazawa, I.3    Sano, K.4
  • 134
    • 0027407015 scopus 로고
    • Chronic intranigral administration of brain-derived neurotrophic factor produces striatal dopami-nergic hypofunction in unlesioned adult rats and fails to attenuate the decline of striatal dopaminergic function following medial forebrain bundle transection
    • Lapchak PA, Beck KD, Araujo DM, Irwin I, Langston JW, Hefti F. Chronic intranigral administration of brain-derived neurotrophic factor produces striatal dopami-nergic hypofunction in unlesioned adult rats and fails to attenuate the decline of striatal dopaminergic function following medial forebrain bundle transection. Neuroscience 1993; 53: 639-650.
    • (1993) Neuroscience , vol.53 , pp. 639-650
    • Lapchak, P.A.1    Beck, K.D.2    Araujo, D.M.3    Irwin, I.4    Langston, J.W.5    Hefti, F.6
  • 135
    • 0036897551 scopus 로고    scopus 로고
    • Widespread and long-lasting alterations in GABA(a)-receptor subtypes after focal cortical infarcts in rats: Mediation by NMDA-dependent processes
    • Redecker C, Wang W, Fritschy JM, Witte OW. Widespread and long-lasting alterations in GABA(a)-receptor subtypes after focal cortical infarcts in rats: mediation by NMDA-dependent processes. J Cereb Blood Flow Metab 2002; 22: 1463-1475.
    • (2002) J Cereb Blood Flow Metab , vol.22 , pp. 1463-1475
    • Redecker, C.1    Wang, W.2    Fritschy, J.M.3    Witte, O.W.4
  • 136
    • 24144440460 scopus 로고    scopus 로고
    • Secondary degeneration of the substantia nigra and corticospinal tract after hemorrhagic middle cerebral artery infarction: Diffusion-weighted MR findings
    • Kinoshita T, Moritani T, Shrier DA, Wang HZ, Hiwatashi A, Numaguchi Y et al. Secondary degeneration of the substantia nigra and corticospinal tract after hemorrhagic middle cerebral artery infarction: diffusion-weighted MR findings. Magn Reson Med Sci 2002; 1: 175-178.
    • (2002) Magn Reson Med Sci , vol.1 , pp. 175-178
    • Kinoshita, T.1    Moritani, T.2    Shrier, D.A.3    Wang, H.Z.4    Hiwatashi, A.5    Numaguchi, Y.6
  • 137
    • 74549213830 scopus 로고    scopus 로고
    • Signal change of the substantia nigra on diffusion-weighted imaging following striatal infarction
    • Nakajima M, Hirano T, Terasaki T, Uchino M. Signal change of the substantia nigra on diffusion-weighted imaging following striatal infarction. Intern Med 2010; 49: 65-68.
    • (2010) Intern Med , vol.49 , pp. 65-68
    • Nakajima, M.1    Hirano, T.2    Terasaki, T.3    Uchino, M.4
  • 138
    • 0042130037 scopus 로고    scopus 로고
    • MR imaging of postischemic neuronal death in the substantia nigra and thala-mus following middle cerebral artery occlusion in rats
    • Abe O, Nakane M, Aoki S, Hayashi N, Masumoto T, Kunimatsu A et al. MR imaging of postischemic neuronal death in the substantia nigra and thala-mus following middle cerebral artery occlusion in rats. NMR Biomed 2003; 16: 152-159.
    • (2003) NMR Biomed , vol.16 , pp. 152-159
    • Abe, O.1    Nakane, M.2    Aoki, S.3    Hayashi, N.4    Masumoto, T.5    Kunimatsu, A.6
  • 141
    • 0034633791 scopus 로고    scopus 로고
    • Thalamic microglial activation in ischemic stroke detected in vivo by pet and [11c]pk1195
    • Pappata S, Levasseur M, Gunn RN, Myers R, Crouzel C, Syrota A et al. Thalamic microglial activation in ischemic stroke detected in vivo by pet and [11c]pk1195. Neurology 2000; 55: 1052-1054.
    • (2000) Neurology , vol.55 , pp. 1052-1054
    • Pappata, S.1    Levasseur, M.2    Gunn, R.N.3    Myers, R.4    Crouzel, C.5    Syrota, A.6
  • 142
    • 84855461934 scopus 로고    scopus 로고
    • A micropet study of the regional distribution of [11c]-pk11195 binding following temporary focal cerebral ischemia in the rat. Correlation with postmortem mapping of microglia activation
    • Hughes JL, Jones PS, Beech JS, Wang D, Menon DK, Aigbirhio FI et al. A micropet study of the regional distribution of [11c]-pk11195 binding following temporary focal cerebral ischemia in the rat. Correlation with postmortem mapping of microglia activation. Neuroimage 2012; 59: 2007-2016.
    • (2012) Neuroimage , vol.59 , pp. 2007-2016
    • Hughes, J.L.1    Jones, P.S.2    Beech, J.S.3    Wang, D.4    Menon, D.K.5    Aigbirhio, F.I.6
  • 143
    • 0013640839 scopus 로고    scopus 로고
    • Effects of ym872 on atrophy of substantia nigra reticulata after focal ischemia in rats
    • Ni JW, Takahashi M, Yatsugi S, Shimizu-Sasamata M, Yamaguchi T. Effects of ym872 on atrophy of substantia nigra reticulata after focal ischemia in rats. Neuroreport 1998; 9: 3719-3724.
    • (1998) Neuroreport , vol.9 , pp. 3719-3724
    • Ni, J.W.1    Takahashi, M.2    Yatsugi, S.3    Shimizu-Sasamata, M.4    Yamaguchi, T.5
  • 144
    • 0030451205 scopus 로고    scopus 로고
    • Involvement of N-methyl-D-aspartate receptor in the delayed transneuronal regression of substantia nigra neurons in rats
    • Yamada K, Goto S, Yoshikawa M, Okamura A, Ushio Y. Involvement of N-methyl-D-aspartate receptor in the delayed transneuronal regression of substantia nigra neurons in rats. Brain Res 1996; 743: 233-239.
    • (1996) Brain Res , vol.743 , pp. 233-239
    • Yamada, K.1    Goto, S.2    Yoshikawa, M.3    Okamura, A.4    Ushio, Y.5
  • 145
    • 0031974191 scopus 로고    scopus 로고
    • Transient increase of manganese-superoxide dismutase in remote brain areas after focal photo-thrombotic cortical lesion
    • Bidmon HJ, Kato K, Schleicher A, Witte OW, Zilles K. Transient increase of manganese-superoxide dismutase in remote brain areas after focal photo-thrombotic cortical lesion. Stroke 1998; 29: 203-210.
    • (1998) Stroke , vol.29 , pp. 203-210
    • Bidmon, H.J.1    Kato, K.2    Schleicher, A.3    Witte, O.W.4    Zilles, K.5
  • 147
    • 0018225006 scopus 로고
    • Carotid artery occlusion and computed tomography. A clinicoradiological study
    • Radu EW, Moseley IF. Carotid artery occlusion and computed tomography. A clinicoradiological study. Neuroradiology 1978; 17: 7-12.
    • (1978) Neuroradiology , vol.17 , pp. 7-12
    • Radu, E.W.1    Moseley, I.F.2
  • 149
    • 0027472490 scopus 로고
    • Callosal atrophy with reduced cortical oxygen metabolism in carotid artery disease
    • Yamauchi H, Fukuyama H, Nabatame H, Harada K, Kimura J. Callosal atrophy with reduced cortical oxygen metabolism in carotid artery disease. Stroke 1993; 24: 88-93.
    • (1993) Stroke , vol.24 , pp. 88-93
    • Yamauchi, H.1    Fukuyama, H.2    Nabatame, H.3    Harada, K.4    Kimura, J.5
  • 150
    • 0029088287 scopus 로고
    • Progression of atrophy of the corpus callosum with deterioration of cerebral cortical oxygen metabolism after carotid artery occlusion: A follow up study with MRI and pet
    • Yamauchi H, Pagani M, Fukuyama H, Ouchi Y, Nagahama Y, Matsuzaki S et al. Progression of atrophy of the corpus callosum with deterioration of cerebral cortical oxygen metabolism after carotid artery occlusion: a follow up study with MRI and pet. J Neurol Neurosurg Psychiatry 1995; 59: 420-426.
    • (1995) J Neurol Neurosurg Psychiatry , vol.59 , pp. 420-426
    • Yamauchi, H.1    Pagani, M.2    Fukuyama, H.3    Ouchi, Y.4    Nagahama, Y.5    Matsuzaki, S.6
  • 151
    • 0029824351 scopus 로고    scopus 로고
    • Atrophy of the corpus callosum associated with cognitive impairment and widespread cortical hypometabolism in carotid artery occlusive disease
    • Yamauchi H, Fukuyama H, Nagahama Y, Katsumi Y, Dong Y, Konishi J et al. Atrophy of the corpus callosum associated with cognitive impairment and widespread cortical hypometabolism in carotid artery occlusive disease. Arch Neurol 1996; 53: 1103-1109.
    • (1996) Arch Neurol , vol.53 , pp. 1103-1109
    • Yamauchi, H.1    Fukuyama, H.2    Nagahama, Y.3    Katsumi, Y.4    Dong, Y.5    Konishi, J.6
  • 152
    • 0034643833 scopus 로고    scopus 로고
    • Long-term changes of hemodynamics and metabolism after carotid artery occlusion
    • Yamauchi H, Fukuyama H, Nagahama Y, Oyanagi C, Okazawa H, Ueno M et al. Long-term changes of hemodynamics and metabolism after carotid artery occlusion. Neurology 2000; 54: 2095-2102.
    • (2000) Neurology , vol.54 , pp. 2095-2102
    • Yamauchi, H.1    Fukuyama, H.2    Nagahama, Y.3    Oyanagi, C.4    Okazawa, H.5    Ueno, M.6
  • 154
    • 0025165723 scopus 로고
    • Hemodynamics in internal carotid artery occlusion examined by positron emission tomography
    • Yamauchi H, Fukuyama H, Kimura J, Konishi J, Kameyama M. Hemodynamics in internal carotid artery occlusion examined by positron emission tomography. Stroke 1990; 21: 1400-1406.
    • (1990) Stroke , vol.21 , pp. 1400-1406
    • Yamauchi, H.1    Fukuyama, H.2    Kimura, J.3    Konishi, J.4    Kameyama, M.5
  • 155
    • 0031855647 scopus 로고    scopus 로고
    • Iodine-123-iomazenil and iodine-123-iodoamphetamine spect in major cerebral artery occlusive disease
    • Moriwaki H, Matsumoto M, Hashikawa K, Oku N, Ishida M, Seike Y et al. Iodine-123-iomazenil and iodine-123-iodoamphetamine spect in major cerebral artery occlusive disease. J Nucl Med 1998; 39: 1348-1353.
    • (1998) J Nucl Med , vol.39 , pp. 1348-1353
    • Moriwaki, H.1    Matsumoto, M.2    Hashikawa, K.3    Oku, N.4    Ishida, M.5    Seike, Y.6
  • 156
    • 0034055138 scopus 로고    scopus 로고
    • Atrophy of the corpus callosum associated with a decrease in cortical benzo-diazepine receptor in large cerebral arterial occlusive diseases
    • Yamauchi H, Fukuyama H, Dong Y, Nabatame H, Nagahama Y, Nishizawa S et al. Atrophy of the corpus callosum associated with a decrease in cortical benzo-diazepine receptor in large cerebral arterial occlusive diseases. J Neurol Neuro-surg Psychiatry 2000; 68: 317-322.
    • (2000) J Neurol Neuro-surg Psychiatry , vol.68 , pp. 317-322
    • Yamauchi, H.1    Fukuyama, H.2    Dong, Y.3    Nabatame, H.4    Nagahama, Y.5    Nishizawa, S.6
  • 157
    • 3242733242 scopus 로고    scopus 로고
    • Reduced blood flow and preserved vasoreactivity characterize oxygen hypometabolism due to incomplete infarction in occlusive carotid artery diseases
    • Kuroda S, Shiga T, Ishikawa T, Houkin K, Narita T, Katoh C et al. Reduced blood flow and preserved vasoreactivity characterize oxygen hypometabolism due to incomplete infarction in occlusive carotid artery diseases. J Nucl Med 2004; 45: 943-949.
    • (2004) J Nucl Med , vol.45 , pp. 943-949
    • Kuroda, S.1    Shiga, T.2    Ishikawa, T.3    Houkin, K.4    Narita, T.5    Katoh, C.6
  • 158
    • 33644859807 scopus 로고    scopus 로고
    • Cerebral oxygen hypometabolism and neuronal integrity in patients with impaired vasoreactivity attributable to occlusive carotid artery diseases
    • Kuroda S, Shiga T, Houkin K, Ishikawa T, Katoh C, Tamaki N et al. Cerebral oxygen hypometabolism and neuronal integrity in patients with impaired vasoreactivity attributable to occlusive carotid artery diseases. Stroke 2006; 37: 393-398.
    • (2006) Stroke , vol.37 , pp. 393-398
    • Kuroda, S.1    Shiga, T.2    Houkin, K.3    Ishikawa, T.4    Katoh, C.5    Tamaki, N.6
  • 160
    • 34249945751 scopus 로고    scopus 로고
    • Selective neuronal damage and chronic hemodynamic cerebral ischemia
    • Yamauchi H, Kudoh T, Kishibe Y, Iwasaki J, Kagawa S. Selective neuronal damage and chronic hemodynamic cerebral ischemia. Ann Neurol 2007; 61: 454-465.
    • (2007) Ann Neurol , vol.61 , pp. 454-465
    • Yamauchi, H.1    Kudoh, T.2    Kishibe, Y.3    Iwasaki, J.4    Kagawa, S.5
  • 161
    • 73449086287 scopus 로고    scopus 로고
    • Hemodynamic compromise as a cause of internal border-zone infarction and cortical neuronal damage in atherosclerotic middle cerebral artery disease
    • Yamauchi H, Nishii R, Higashi T, Kagawa S, Fukuyama H. Hemodynamic compromise as a cause of internal border-zone infarction and cortical neuronal
    • (2009) Stroke , vol.40 , pp. 3730-3735
    • Yamauchi, H.1    Nishii, R.2    Higashi, T.3    Kagawa, S.4    Fukuyama, H.5
  • 162
    • 78751529698 scopus 로고    scopus 로고
    • Selective neuronal damage and Wisconsin card sorting test performance in atherosclerotic occlu-sive disease of the major cerebral artery
    • Yamauchi H, Nishii R, Higashi T, Kagawa S, Fukuyama H. Selective neuronal damage and Wisconsin card sorting test performance in atherosclerotic occlu-sive disease of the major cerebral artery. J Neurol Neurosurg Psychiatry 2011; 82: 150-156.
    • (2011) J Neurol Neurosurg Psychiatry , vol.82 , pp. 150-156
    • Yamauchi, H.1    Nishii, R.2    Higashi, T.3    Kagawa, S.4    Fukuyama, H.5
  • 163
    • 85027925608 scopus 로고    scopus 로고
    • Silent cortical neuronal damage in atherosclerotic disease of the major cerebral arteries
    • Yamauchi H, Nishii R, Higashi T, Kagawa S, Fukuyama H. Silent cortical neuronal damage in atherosclerotic disease of the major cerebral arteries. J Cereb Blood Flow Metab 2011; 31: 953-961.
    • (2011) J Cereb Blood Flow Metab , vol.31 , pp. 953-961
    • Yamauchi, H.1    Nishii, R.2    Higashi, T.3    Kagawa, S.4    Fukuyama, H.5
  • 165
    • 0026063830 scopus 로고
    • Cerebral hemodynamics in ischemic cerebrovascular disease
    • Powers WJ. Cerebral hemodynamics in ischemic cerebrovascular disease. Ann Neurol 1991; 29: 231-240.
    • (1991) Ann Neurol , vol.29 , pp. 231-240
    • Powers, W.J.1
  • 166
    • 0026551717 scopus 로고
    • Significance of low perfusion with increased oxygen extraction fraction in a case of internal carotid artery stenosis
    • Yamauchi H, Fukuyama H, Fujimoto N, Nabatame H, Kimura J. Significance of low perfusion with increased oxygen extraction fraction in a case of internal carotid artery stenosis. Stroke 1992; 23: 431-432.
    • (1992) Stroke , vol.23 , pp. 431-432
    • Yamauchi, H.1    Fukuyama, H.2    Fujimoto, N.3    Nabatame, H.4    Kimura, J.5
  • 167
    • 77956832375 scopus 로고    scopus 로고
    • Haemodynamic stroke: Clinical features, prognosis, and management
    • Klijn CJ, Kappelle LJ. Haemodynamic stroke: clinical features, prognosis, and management. Lancet Neurol. 2010; 9: 1008-1017.
    • (2010) Lancet Neurol. , vol.9 , pp. 1008-1017
    • Klijn, C.J.1    Kappelle, L.J.2
  • 168
    • 84864658307 scopus 로고    scopus 로고
    • Is misery perfusion still a predictor of stroke in symptomatic major cerebral artery disease?
    • Yamauchi H, Higashi T, Kagawa S, Nishii R, Kudo T, Sugimoto K et al. Is misery perfusion still a predictor of stroke in symptomatic major cerebral artery disease? Brain 2012; 135: 2515-2526.
    • (2012) Brain , vol.135 , pp. 2515-2526
    • Yamauchi, H.1    Higashi, T.2    Kagawa, S.3    Nishii, R.4    Kudo, T.5    Sugimoto, K.6
  • 169
    • 77954177565 scopus 로고    scopus 로고
    • Watershed infarcts in transient ischemic attack/minor stroke withXor 50% carotid stenosis: Hemodynamic or embolic?
    • Moustafa RR, Izquierdo-Garcia D, Jones PS, Graves MJ, Fryer TD, Gillard JH et al. Watershed infarcts in transient ischemic attack/minor stroke withXor 50% carotid stenosis: hemodynamic or embolic? Stroke 2010; 41: 1410-1416.
    • (2010) Stroke , vol.41 , pp. 1410-1416
    • Moustafa, R.R.1    Izquierdo-Garcia, D.2    Jones, P.S.3    Graves, M.J.4    Fryer, T.D.5    Gillard, J.H.6
  • 170
    • 80054997768 scopus 로고    scopus 로고
    • Microembolism versus hemodynamic impairment in rosary-like deep watershed infarcts: A combined positron emission tomography and transcranial Doppler study
    • Moustafa RR, Momjian-Mayor I, Jones PS, Morbelli S, Day DJ, Aigbirhio FI et al. Microembolism versus hemodynamic impairment in rosary-like deep watershed infarcts: a combined positron emission tomography and transcranial Doppler study. Stroke 2011; 42: 3138-3143.
    • (2011) Stroke , vol.42 , pp. 3138-3143
    • Moustafa, R.R.1    Momjian-Mayor, I.2    Jones, P.S.3    Morbelli, S.4    Day, D.J.5    Aigbirhio, F.I.6
  • 171
    • 60549083260 scopus 로고    scopus 로고
    • Postoperative cortical neural loss associated with cerebral hyperperfusion and cognitive impairment after carotid endarterectomy: 123i-iomazenil spect study
    • Chida K, Ogasawara K, Suga Y, Saito H, Kobayashi M, Yoshida K et al. Postoperative cortical neural loss associated with cerebral hyperperfusion and cognitive impairment after carotid endarterectomy: 123i-iomazenil spect study. Stroke 2009; 40: 448-453.
    • (2009) Stroke , vol.40 , pp. 448-453
    • Chida, K.1    Ogasawara, K.2    Suga, Y.3    Saito, H.4    Kobayashi, M.5    Yoshida, K.6
  • 172
    • 75549088752 scopus 로고    scopus 로고
    • Postcarotid endarterectomy improvement in cognition is associated with resolution of crossed cerebellar hypoperfusion and increase in 123i-iomazenil uptake in the cerebral cortex: A spect study
    • Chida K, Ogasawara K, Aso K, Suga Y, Kobayashi M, Yoshida K et al. Postcarotid endarterectomy improvement in cognition is associated with resolution of crossed cerebellar hypoperfusion and increase in 123i-iomazenil uptake in the cerebral cortex: a spect study. Cerebrovasc Dis 2010; 29: 343-351.
    • (2010) Cerebrovasc Dis , vol.29 , pp. 343-351
    • Chida, K.1    Ogasawara, K.2    Aso, K.3    Suga, Y.4    Kobayashi, M.5    Yoshida, K.6
  • 173
    • 79958277837 scopus 로고    scopus 로고
    • Surgical revascularization reverses cerebral cortical thinning in patients with severe cerebrovascular steno-occlusive disease
    • Fierstra J, Maclean DB, Fisher JA, Han JS, Mandell DM, Conklin J et al. Surgical revascularization reverses cerebral cortical thinning in patients with severe cerebrovascular steno-occlusive disease. Stroke 2011; 42: 1631-1637.
    • (2011) Stroke , vol.42 , pp. 1631-1637
    • Fierstra, J.1    Maclean, D.B.2    Fisher, J.A.3    Han, J.S.4    Mandell, D.M.5    Conklin, J.6
  • 174
    • 84874948266 scopus 로고    scopus 로고
    • Antihypertensive treatment can prevent stroke and cognitive decline
    • Soros P, Whitehead S, Spence JD, Hachinski V. Antihypertensive treatment can prevent stroke and cognitive decline. Nat Rev Neurol 2013; 9: 174-178.
    • (2013) Nat Rev Neurol , vol.9 , pp. 174-178
    • Soros, P.1    Whitehead, S.2    Spence, J.D.3    Hachinski, V.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.