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Volumn 6, Issue , 2016, Pages

Neutrophil Elastase-mediated proteolysis activates the anti-inflammatory cytokine IL-36 Receptor antagonist

Author keywords

[No Author keywords available]

Indexed keywords

ANTIINFLAMMATORY AGENT; IL36RN PROTEIN, HUMAN; INTERLEUKIN DERIVATIVE; LEUKOCYTE ELASTASE;

EID: 84964277318     PISSN: None     EISSN: 20452322     Source Type: Journal    
DOI: 10.1038/srep24880     Document Type: Article
Times cited : (77)

References (27)
  • 2
    • 47049083783 scopus 로고    scopus 로고
    • Psoriasis and metabolic disease: Epidemiology and pathophysiology
    • Azfar, R. S. & Gelfand, J. M. Psoriasis and metabolic disease: epidemiology and pathophysiology. Curr Opin Rheumatol. 20, 416-422 (2008).
    • (2008) Curr Opin Rheumatol , vol.20 , pp. 416-422
    • Azfar, R.S.1    Gelfand, J.M.2
  • 3
    • 33751546237 scopus 로고    scopus 로고
    • IL-23 stimulates epidermal hyperplasia via TNF and IL-20R2-dependent mechanisms with implications for psoriasis pathogenesis
    • Chan, J. R. et al. IL-23 stimulates epidermal hyperplasia via TNF and IL-20R2-dependent mechanisms with implications for psoriasis pathogenesis. J Exp Med. 203, 2577-2587 (2006).
    • (2006) J Exp Med , vol.203 , pp. 2577-2587
    • Chan, J.R.1
  • 4
    • 38849187386 scopus 로고    scopus 로고
    • IL-22 is required for Th17 cell-mediated pathology in a mouse model of psoriasis-like skin inflammation
    • Ma, H. L. et al. IL-22 is required for Th17 cell-mediated pathology in a mouse model of psoriasis-like skin inflammation. J Clin Invest. 118, 597-607 (2008).
    • (2008) J Clin Invest , vol.118 , pp. 597-607
    • Ma, H.L.1
  • 5
    • 84925381286 scopus 로고    scopus 로고
    • IL-36gamma (IL-1F9) is a biomarker for psoriasis skin lesions
    • D'Erme, A. M. et al. IL-36gamma (IL-1F9) is a biomarker for psoriasis skin lesions. J Invest Dermatol. 135, 1025-1032 (2015).
    • (2015) J Invest Dermatol , vol.135 , pp. 1025-1032
    • D'Erme, A.M.1
  • 6
    • 1842640230 scopus 로고    scopus 로고
    • Interleukin (IL)-1F6, IL-1F8, and IL-1F9 signal through IL-1Rrp2 and IL-1RAcP to activate the pathway leading to NF-kappaB and MAPKs
    • Towne, J. E., Garka, K. E., Renshaw, B. R., Virca, G. D. & Sims, J. E. Interleukin (IL)-1F6, IL-1F8, and IL-1F9 signal through IL-1Rrp2 and IL-1RAcP to activate the pathway leading to NF-kappaB and MAPKs. J Biol Chem. 279, 13677-13688 (2004).
    • (2004) J Biol Chem , vol.279 , pp. 13677-13688
    • Towne, J.E.1    Garka, K.E.2    Renshaw, B.R.3    Virca, G.D.4    Sims, J.E.5
  • 7
    • 82755163088 scopus 로고    scopus 로고
    • Interleukin-36 (IL-36) ligands require processing for full agonist (IL-36alpha, IL-36beta, and IL-36gamma) or antagonist (IL-36Ra) activity
    • Towne, J. E. et al. Interleukin-36 (IL-36) ligands require processing for full agonist (IL-36alpha, IL-36beta, and IL-36gamma) or antagonist (IL-36Ra) activity. J Biol Chem. 286, 42594-42602 (2011).
    • (2011) J Biol Chem , vol.286 , pp. 42594-42602
    • Towne, J.E.1
  • 8
    • 35748940015 scopus 로고    scopus 로고
    • Opposing activities of two novel members of the IL-1 ligand family regulate skin inflammation
    • Blumberg, H. et al. Opposing activities of two novel members of the IL-1 ligand family regulate skin inflammation. J Exp Med. 204, 2603-2614 (2007).
    • (2007) J Exp Med , vol.204 , pp. 2603-2614
    • Blumberg, H.1
  • 9
    • 84860390352 scopus 로고    scopus 로고
    • Interleukin-36-receptor antagonist deficiency and generalized pustular psoriasis
    • Marrakchi, S. et al. Interleukin-36-receptor antagonist deficiency and generalized pustular psoriasis. N Engl J Med. 365, 620-628 (2011).
    • (2011) N Engl J Med , vol.365 , pp. 620-628
    • Marrakchi, S.1
  • 10
    • 84904264198 scopus 로고    scopus 로고
    • Molecular Determinants of Agonist and Antagonist Signaling through the IL-36 Receptor
    • Gunther, S. & Sundberg, E. J. Molecular Determinants of Agonist and Antagonist Signaling through the IL-36 Receptor. J Immunol. 193, 921-930 (2014).
    • (2014) J Immunol , vol.193 , pp. 921-930
    • Gunther, S.1    Sundberg, E.J.2
  • 11
    • 84871608956 scopus 로고    scopus 로고
    • Mutation analysis of the IL36RN gene in 14 Japanese patients with generalized pustular psoriasis
    • Farooq, M. et al. Mutation analysis of the IL36RN gene in 14 Japanese patients with generalized pustular psoriasis. Hum Mutat. 34, 176-183 (2013).
    • (2013) Hum Mutat , vol.34 , pp. 176-183
    • Farooq, M.1
  • 12
    • 84958115094 scopus 로고    scopus 로고
    • Neutrophil-Derived Proteases Escalate Inflammation through Activation of IL-36 Family Cytokines
    • Henry, C. M. et al. Neutrophil-Derived Proteases Escalate Inflammation through Activation of IL-36 Family Cytokines. Cell Rep. 14, 708-722 (2016).
    • (2016) Cell Rep , vol.14 , pp. 708-722
    • Henry, C.M.1
  • 13
    • 82155183309 scopus 로고    scopus 로고
    • IL-36R ligands are potent regulators of dendritic and T cells
    • Vigne, S. et al. IL-36R ligands are potent regulators of dendritic and T cells. Blood. 118, 5813-5823 (2011).
    • (2011) Blood , vol.118 , pp. 5813-5823
    • Vigne, S.1
  • 14
    • 84902130454 scopus 로고    scopus 로고
    • IL-36 Promotes Myeloid Cell Infiltration, Activation, and Inflammatory Activity in Skin
    • Foster, A. M. et al. IL-36 Promotes Myeloid Cell Infiltration, Activation, and Inflammatory Activity in Skin. J Immunol. 192, 6053-6061 (2014).
    • (2014) J Immunol , vol.192 , pp. 6053-6061
    • Foster, A.M.1
  • 15
    • 80855137955 scopus 로고    scopus 로고
    • Inter-regulation of Th17 cytokines and the IL-36 cytokines in vitro and in vivo: Implications in psoriasis pathogenesis
    • Carrier, Y. et al. Inter-regulation of Th17 cytokines and the IL-36 cytokines in vitro and in vivo: implications in psoriasis pathogenesis. J Invest Dermatol. 131, 2428-2437 (2011).
    • (2011) J Invest Dermatol , vol.131 , pp. 2428-2437
    • Carrier, Y.1
  • 16
    • 84859485590 scopus 로고    scopus 로고
    • Expression of IL-1Rrp2 by human myelomonocytic cells is unique to DCs and facilitates DC maturation by IL-1F8 and IL-1F9
    • Mutamba, S., Allison, A., Mahida, Y., Barrow, P. & Foster, N. Expression of IL-1Rrp2 by human myelomonocytic cells is unique to DCs and facilitates DC maturation by IL-1F8 and IL-1F9. Eur J Immunol. 42, 607-617 (2012).
    • (2012) Eur J Immunol , vol.42 , pp. 607-617
    • Mutamba, S.1    Allison, A.2    Mahida, Y.3    Barrow, P.4    Foster, N.5
  • 17
    • 84925650548 scopus 로고    scopus 로고
    • IL-36gamma sustains a proinflammatory self-amplifying loop with IL-17C in anti-TNF-induced psoriasiform skin lesions of patients with Crohn's disease
    • Friedrich, M., Tillack, C., Wollenberg, A., Schauber, J. & Brand, S. IL-36gamma sustains a proinflammatory self-amplifying loop with IL-17C in anti-TNF-induced psoriasiform skin lesions of patients with Crohn's disease. Inflamm Bowel Dis. 20, 1891-1901 (2014).
    • (2014) Inflamm Bowel Dis , vol.20 , pp. 1891-1901
    • Friedrich, M.1    Tillack, C.2    Wollenberg, A.3    Schauber, J.4    Brand, S.5
  • 18
    • 57149094731 scopus 로고    scopus 로고
    • Distinct regulatory profiles of interleukins and chemokines in response to cigarette smoke condensate in normal human bronchial epithelial (NHBE) cells
    • Parsanejad, R., Fields, W. R., Steichen, T. J., Bombick, B. R. & Doolittle, D. J. Distinct regulatory profiles of interleukins and chemokines in response to cigarette smoke condensate in normal human bronchial epithelial (NHBE) cells. J Interferon Cytokine Res. 28, 703-712 (2008).
    • (2008) J Interferon Cytokine Res , vol.28 , pp. 703-712
    • Parsanejad, R.1    Fields, W.R.2    Steichen, T.J.3    Bombick, B.R.4    Doolittle, D.J.5
  • 19
    • 77249119309 scopus 로고    scopus 로고
    • Rhinovirus-induced modulation of gene expression in bronchial epithelial cells from subjects with asthma
    • Bochkov, Y. A. et al. Rhinovirus-induced modulation of gene expression in bronchial epithelial cells from subjects with asthma. Mucosal Immunol. 3, 69-80 (2010).
    • (2010) Mucosal Immunol , vol.3 , pp. 69-80
    • Bochkov, Y.A.1
  • 20
    • 21244442629 scopus 로고    scopus 로고
    • Transcriptional response of bronchial epithelial cells to Pseudomonas aeruginosa: Identification of early mediators of host defense
    • Vos, J. B. et al. Transcriptional response of bronchial epithelial cells to Pseudomonas aeruginosa: identification of early mediators of host defense. Physiol Genomics. 21, 324-336 (2005).
    • (2005) Physiol Genomics , vol.21 , pp. 324-336
    • Vos, J.B.1
  • 22
    • 84873749349 scopus 로고    scopus 로고
    • The IL-36 receptor pathway regulates Aspergillus fumigatus-induced Th1 and Th17 responses
    • Gresnigt, M. S. et al. The IL-36 receptor pathway regulates Aspergillus fumigatus-induced Th1 and Th17 responses. Eur J Immunol. 43, 416-426 (2013).
    • (2013) Eur J Immunol , vol.43 , pp. 416-426
    • Gresnigt, M.S.1
  • 23
    • 82455175456 scopus 로고    scopus 로고
    • Granzyme B-dependent proteolysis acts as a switch to enhance the proinflammatory activity of IL-1alpha
    • Afonina, I. S. et al. Granzyme B-dependent proteolysis acts as a switch to enhance the proinflammatory activity of IL-1alpha. Mol Cell. 44, 265-278 (2011).
    • (2011) Mol Cell , vol.44 , pp. 265-278
    • Afonina, I.S.1
  • 24
    • 0023947763 scopus 로고
    • Generation of biologically active interleukin-1 beta by proteolytic cleavage of the inactive precursor
    • Black, R. A. et al. Generation of biologically active interleukin-1 beta by proteolytic cleavage of the inactive precursor. J Biol Chem. 263, 9437-9442 (1988).
    • (1988) J Biol Chem , vol.263 , pp. 9437-9442
    • Black, R.A.1
  • 25
    • 0025220123 scopus 로고
    • Processing of precursor interleukin 1 beta and inflammatory disease
    • Hazuda, D. J., Strickler, J., Kueppers, F., Simon, P. L. & Young, P. R. Processing of precursor interleukin 1 beta and inflammatory disease. J Biol Chem. 265, 6318-6322 (1990).
    • (1990) J Biol Chem , vol.265 , pp. 6318-6322
    • Hazuda, D.J.1    Strickler, J.2    Kueppers, F.3    Simon, P.L.4    Young, P.R.5
  • 26
    • 73249144903 scopus 로고    scopus 로고
    • Inflammatory arthritis in caspase 1 gene-deficient mice: Contribution of proteinase 3 to caspase 1-independent production of bioactive interleukin-1beta
    • Joosten, L. A. et al. Inflammatory arthritis in caspase 1 gene-deficient mice: contribution of proteinase 3 to caspase 1-independent production of bioactive interleukin-1beta. Arthritis Rheum. 60, 3651-3662 (2009).
    • (2009) Arthritis Rheum , vol.60 , pp. 3651-3662
    • Joosten, L.A.1
  • 27
    • 84857134135 scopus 로고    scopus 로고
    • IL-33 is processed into mature bioactive forms by neutrophil elastase and cathepsin G
    • Lefrancais, E. et al. IL-33 is processed into mature bioactive forms by neutrophil elastase and cathepsin G. Proc Natl Acad Sci USA 109, 1673-1678 (2012).
    • (2012) Proc Natl Acad Sci USA , vol.109 , pp. 1673-1678
    • Lefrancais, E.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.