Diallyl disulfide enhances carbon ion beams- induced apoptotic cell death in cervical cancer cells through regulating Tap73 /ΔNp73

Cell Cycle

Volumn 14, Issue 23, 2015, Pages 3725-3733

  Di, Cuixia ^a,b,c   Sun, Chao ^a,b,c   Li, Hongyan ^a,b,c   Si, Jing ^a,b,c   Zhang, Hong ^a,b,c   Han, Lu ^a,b,c   Zhao, Qiuyue ^a,b,c   Liu, Yang ^a,b,c   Liu, Bin ^d   Miao, Guoying ^a,b,c   Gan, Lu ^a,b,c   Liu, Yuanyuan ^a,b,c  

^a INSTITUTE OF MODERN PHYSICS   (China)

^b INSTITUTE OF GEOLOGY AND GEOPHYSICS   (China)

^c Key Laboratory of Heavy Ion Radiation Medicine of Gansu Province   (China)

^d LANZHOU UNIVERSITY   (China)

Author keywords

Apoptosis; Cervical carcinoma; Diallyl disulfide; high LET carbon beam; Radiosensitivity; Tap73; Np73

Indexed keywords

APOPTOTIC PROTEASE ACTIVATING FACTOR 1; DIALLYL DISULFIDE; INTERLEUKIN 10; PROTEIN; PROTEIN FASLG; PROTEIN NP73; PROTEIN P53; PROTEIN PCBP1; PROTEIN TAP73; RADIOSENSITIZING AGENT; TRANSCRIPTION FACTOR; UNCLASSIFIED DRUG; ALLYL COMPOUND; DELTA NP73 PROTEIN, HUMAN; DISULFIDE; DNA BINDING PROTEIN; NUCLEAR PROTEIN; P73 PROTEIN, HUMAN; TUMOR PROTEIN P73; TUMOR SUPPRESSOR PROTEIN;

APOPTOSIS; ARTICLE; CANCER INHIBITION; CELL DEATH; CELL VIABILITY; CELLULAR DISTRIBUTION; CERVICAL CANCER CELL LINE; CONTROLLED STUDY; FEMALE; GENE EXPRESSION; HELA CELL LINE; HUMAN; HUMAN CELL; IMMUNOFLUORESCENCE; ION THERAPY; M PHASE CELL CYCLE CHECKPOINT; PROTEIN EXPRESSION; RADIATION RESPONSE; RADIOSENSITIVITY; REAL TIME POLYMERASE CHAIN REACTION; UPREGULATION; UTERINE CERVIX CANCER; WESTERN BLOTTING; CELL CYCLE CHECKPOINT; DRUG EFFECTS; GENETICS; UTERINE CERVICAL NEOPLASMS;

ALLYL COMPOUNDS; APOPTOSIS; CELL CYCLE CHECKPOINTS; DISULFIDES; DNA-BINDING PROTEINS; FEMALE; GENE EXPRESSION; HEAVY ION RADIOTHERAPY; HELA CELLS; HUMANS; NUCLEAR PROTEINS; TUMOR PROTEIN P73; TUMOR SUPPRESSOR PROTEINS; UTERINE CERVICAL NEOPLASMS;

EID: 84964089338     PISSN: 15384101     EISSN: 15514005     Source Type: Journal    
DOI: 10.1080/15384101.2015.1104438     Document Type: Article

References (45)

1. Zagouri F, Sergentanis TN, Chrysikos D, Filipits M, Bartsch R. Molecularly targeted therapies in cervical cancer. A systematic review. Gynecol Oncol 2012; 126: 291-303; PMID: 22504292; http://dx.doi.org/10.1016/j.ygyno.2012.04.007
2. Nakano T, Ohno T, Ishikawa H, Suzuki Y, Takahashi T. Current advancement in radiation therapy for uterine cervical cancer. J Radiat Res 2010; 51: 1-8; PMID: 20173313; http://dx.doi.org/10.1269/jrr.09132
3. Liu SS, Chan KY, Cheung AN, Liao XY, Leung TW, Ngan HY. Expression of deltaNp73 and TAp73alpha independently associated with radiosensitivities and prognoses in cervical squamous cell carcinoma. Clin Cancer Res 2006; 12: 3922-7; PMID: 16818688; http://dx.doi.org/10.1158/1078-0432.CCR-05-2573
4. Safdie F, Brandhorst S, Wei M, Wang W, Lee C, Hwang S, Conti PS, Chen TC, Longo VD. Fasting enhances the response of glioma to chemo-and radiotherapy. PLoS One 2012; 7: e44603; PMID: 22984531; http://dx.doi.org/10.1371/journal.pone.0044603
5. Kamada T, Tsujii H, Blakely EA, Debus J, De NeveW, Durante M, Jakel O, Mayer R, Orecchia R, Potter R, et al. Carbon ion radiotherapy in Japan: an assessment of 20 years of clinical experience. Lancet Oncol 2015; 16: e93-e100; PMID: 25638685; http://dx.doi.org/10.1016/S1470-2045(14)70412-7
6. Liu SS, Chan KY, Leung RC, Law HK, Leung TW, Ngan HY. Enhancement of the radiosensitivity of cervical cancer cells by overexpressing p73alpha. Mol Cancer Ther 2006; 5: 1209-15; PMID: 16731753; http://dx.doi.org/10.1158/1535-7163.MCT-05-0451
7. Di CX, Yang LN, Zhang H, An LZ, Zhang X, Ma XF, Sun C, Wang XH, Yang R, Wu ZH, et al. Effects of carbon-ion beam or X-ray irradiation on anti-apoptosis DeltaNp73 expression in HeLa cells. Gene 2013; 515: 208-13; PMID: 23228853; http://dx.doi.org/10.1016/j.gene.2012.11.040
8. Durante M. Heavy ion radiobiology for hadrontherapy and space radiation protection. Radiother Oncol 2004; 73 Suppl 2: S158-60; PMID: 15971334; http://dx.doi.org/10.1016/S0167-8140(04)80040-9
9. DuranteM. New challenges in high-energy particle radiobiology. Br J Radiol 2014; 87: 20130626; PMID: 24198199; http://dx.doi.org/10.1259/bjr.20130626
10. Diaz-Padilla I, Monk BJ, Mackay HJ, Oaknin A. Treatment of metastatic cervical cancer: future directions involving targeted agents. Crit Rev Oncol Hematol 2013; 85: 303-14; PMID: 22883215; http://dx.doi.org/10.1016/j.critrevonc.2012.07.006
11. Xiao X, Chen B, Liu X, Liu P, Zheng G, Ye F, Tang H, Xie X. Diallyl disulfide suppresses SRC/Ras/ERK signaling-mediated proliferation and metastasis in human breast cancer by up-regulating miR-34a. PLoS One 2014; 9: e112720; PMID: 25396727; http://dx.doi.org/10.1371/journal.pone.0112720
12. Druesne-Pecollo N, Pagniez A, Thomas M, Cherbuy C, Duee PH, Martel P, Chaumontet C. Diallyl disulfide increases CDKN1A promoter-associated histone acetylation in human colon tumor cell lines. J Agric Food Chem 2006; 54: 7503-7; PMID: 17002414; http://dx.doi.org/10.1021/jf061369w
13. Huang J, Yang B, Xiang T, Peng W, Qiu Z, Wan J, Zhang L, Li H, Li H, Ren G. Diallyl disulfide inhibits growth and metastatic potential of human triple-negative breast cancer cells through inactivation of the betacatenin signaling pathway. Mol Nutr Food Res 2015; 59(6): 1063-75; PMID: 25755089; http://dx.doi.org/10.1002/mnfr.201400668
14. Tang H, Kong Y, Guo J, Tang Y, Xie X, Yang L, Su Q, Xie X. Diallyl disulfide suppresses proliferation and induces apoptosis in human gastric cancer through Wnt-1 signaling pathway by up-regulation of miR-200b and miR-22. Cancer Lett 2013; 340: 72-81; PMID: 23851184; http://dx.doi.org/10.1016/j.canlet.2013.06.027
15. Aoki M, Furusawa Y, Yamada T. LET dependency of heavy-ion induced apoptosis in V79 cells. J Radiat Res 2000; 41: 163-75; PMID: 11037583; http://dx.doi.org/10.1269/jrr.41.163
16. Di C, Yang L, Zhang H, Ma X, Zhang X, Sun C, Li H, Xu S, An L, Li X, et al. Mechanisms, function and clinical applications of DNp73. Cell Cycle 2013; 12: 1861-7; PMID: 23708520; http://dx.doi.org/10.4161/cc.24967
17. Irwin MS. Family feud in chemosensitvity: p73 and mutant p53. Cell Cycle 2004; 3: 319-23; PMID: 14739781; http://dx.doi.org/10.4161/cc.3.3.768
18. Taebunpakul P, Sayan BS, Flinterman M, Klanrit P, Gaken J, Odell EW, Melino G, Tavassoli M. Apoptin induces apoptosis by changing the equilibrium between the stability of TAp73 and DeltaNp73 isoforms through ubiquitin ligase PIR2. Apoptosis 2012; 17: 762-76; PMID: 22484480; http://dx.doi.org/10.1007/s10495-012-0720-7
19. Qian Y, Zhang J, Jung YS, Chen X. DEC1 coordinates with HDAC8 to differentially regulate TAp73 and DeltaNp73 expression. PLoS One 2014; 9: e84015; PMID: 24404147; http://dx.doi.org/10.1371/journal. pone.0084015
20. Leung TH, Ngan HY. Interaction of TAp73 and breast cancer-associated gene 3 enhances the sensitivity of cervical cancer cells in response to irradiation-induced apoptosis. Cancer Res 2010; 70: 6486-96; PMID: 20647320; http://dx.doi.org/10.1158/0008-5472.CAN-10-0688
21. Liu SS, Leung RC, Chan KY, Chiu PM, Cheung AN, Tam KF, Ng TY, Wong LC, Ngan HY. p73 expression is associated with the cellular radiosensitivity in cervical cancer after radiotherapy. Clin Cancer Res 2004; 10: 3309-16; PMID: 15161684; http://dx.doi.org/10.1158/1078-0432.CCR-03-0119
22. Debus J, Jackel O, Kraft G, Wannenmacher M. Is there a role for heavy ion beam therapy? Recent Results Cancer Res 1998; 150: 170-82; PMID: 9670291; http://dx.doi.org/10.1007/978-3-642-78774-4_11
23. Kamada T. Clinical evidence of particle beam therapy (carbon). Int J Clin Oncol 2012; 17: 85-8; PMID: 22426888; http://dx.doi.org/10.1007/s10147-012-0388-6
24. Suzuki Y, Nakano T, Ohno T, Oka K. Comparison of the radiobiological effect of carbon ion beam therapy and conventional radiation therapy on cervical cancer. J Radiat Res 2008; 49: 473-9; PMID: 18622131; http://dx.doi.org/10.1269/jrr.07107
25. Suman S, Jain S, Chandna S. Recent patents in the field of radioprotector development: opportunities and challenges. Recent Pat Biotechnol 2013; 7: 219-27; PMID: 24182320; http://dx.doi.org/10.2174/18722083113076660012
26. Devrim E, Durak I. Is garlic a promising food for benign prostatic hyperplasia and prostate cancer? Mol Nutr Food Res 2007; 51: 1319-23; PMID: 17918170; http://dx.doi.org/10.1002/mnfr.200600302
27. Kim SH, Lee IC, Baek HS, Shin IS, Moon C, Bae CS, Kim SH, Kim JC, Kim HC. Mechanism for the protective effect of diallyl disulfide against cyclophosphamide acute urotoxicity in rats. Food Chem Toxicol 2014; 64: 110-8; PMID: 24291451; http://dx.doi.org/10.1016/j.fct.2013.11.023
28. Yi L, Su Q. Molecular mechanisms for the anti-cancer effects of diallyl disulfide. Food Chem Toxicol 2013; 57: 362-70; PMID: 23583486; http://dx.doi.org/10.1016/j.fct.2013.04.001
29. Milner JA. Garlic: its anticarcinogenic and antitumorigenic properties. Nutr Rev 1996; 54: S82-6; PMID: 9110580; http://dx.doi.org/10.1111/j.1753-4887.1996.tb03823.x
30. Nagaraj NS, Anilakumar KR, Singh OV. Diallyl disulfide causes caspase-dependent apoptosis in human cancer cells through a Bax-triggered mitochondrial pathway. J Nutr Biochem 2010; 21: 405-12; PMID: 19423321; http://dx.doi.org/10.1016/j.jnutbio.2009.01.015
31. Arunkumar R, Sharmila G, Elumalai P, Senthilkumar K, Banudevi S, Gunadharini DN, Benson CS, Daisy P, Arunakaran J. Effect of diallyl disulfide on insulin-like growth factor signaling molecules involved in cell survival and proliferation of human prostate cancer cells in vitro and in silico approach through docking analysis. Phytomedicine 2012; 19: 912-23; PMID: 22739413; http://dx.doi.org/10.1016/j.phymed.2012.04.009
32. Wang HC, Yang JH, Hsieh SC, Sheen LY. Allyl sulfides inhibit cell growth of skin cancer cells through induction of DNA damage mediated G2/Marrest and apoptosis. J Agric Food Chem 2010; 58: 7096-103; PMID: 20459099; http://dx.doi.org/10.1021/jf100613x
33. HakemR. DNA-damage repair; the good, the bad, and the ugly. EMBO J 2008; 27: 589-605; PMID: 18285820; http://dx.doi.org/10.1038/emboj.2008.15
34. Fulda S, Debatin KM. Extrinsic versus intrinsic apoptosis pathways in anticancer chemotherapy. Oncogene 2006; 25: 4798-811; PMID: 16892092; http://dx.doi.org/10.1038/sj.onc.1209608
35. Yoshida H, Kong YY, Yoshida R, Elia AJ, Hakem A, Hakem R, Penninger JM, Mak TW. Apaf1 is required for mitochondrial pathways of apoptosis and brain development. Cell 1998; 94: 739-50; PMID: 9753321; http://dx.doi.org/10.1016/S0092-8674(00)81733-X
36. Cecconi F, Alvarez-Bolado G, Meyer BI, Roth KA, Gruss P. Apaf1 (CED-4 homolog) regulates programmed cell death in mammalian development. Cell 1998; 94: 727-37; PMID: 9753320; http://dx.doi.org/10.1016/S0092-8674(00)81732-8
37. Cecconi F. Apaf1 and the apoptotic machinery. Cell Death Differ 1999; 6: 1087-98; PMID: 10578178; http://dx.doi.org/10.1038/sj.cdd.4400602
38. Yang X, Sun B, Wang H, Yin C, Wang X, Ji X. Increased serum IL-10 in lupus patients promotes apoptosis of T cell subsets via the caspase 8 pathway initiated by Fas signaling. J Biomed Res 2015; 29: 232-40; PMID: 26060447
39. Nagata S. Apoptosis by death factor. Cell 1997; 88: 355-65; PMID: 9039262; http://dx.doi.org/10.1016/S0092-8674(00)81874-7
40. Jost CA, Marin MC, Kaelin WG, Jr. p73 is a simian; correction of human p53-related protein that can induce apoptosis. Nature 1997; 389: 191-4; PMID: 9296498; http://dx.doi.org/10.1038/38298
41. Stiewe T, Putzer BM. p73 in apoptosis. Apoptosis 2001; 6: 447-52; PMID: 11595834; http://dx.doi.org/10.1023/A: 1012433522902
42. Holcakova J, Ceskova P, Hrstka R, Muller P, Dubska L, Coates PJ, Palecek E, Vojtesek B. The cell type-specific effect of TAp73 isoforms on the cell cycle and apoptosis. Cell Mol Biol Lett 2008; 13: 404-20; PMID: 18350258; http://dx.doi.org/10.2478/s11658-008-0011-z
43. Ramadan S, Terrinoni A, Catani MV, Sayan AE, Knight RA, Mueller M, Krammer PH, Melino G, Candi E. p73 induces apoptosis by different mechanisms. Biochem Biophys Res Commun 2005; 331: 713-7; PMID: 15865927; http://dx.doi.org/10.1016/j.bbrc.2005.03.156
44. Petrova V, Mancini M, Agostini M, Knight RA, Annicchiarico-Petruzzelli M, Barlev NA, Melino G, Amelio I. TAp73 transcriptionally represses BNIP3 expression. Cell Cycle 2015; 14: 2484-93; PMID: 25950386; http://dx.doi.org/10.1080/15384101.2015.1044178
45. Schuster A, Schilling T, De Laurenzi V, Koch AF, Seitz S, Staib F, Teufel A, Thorgeirsson SS, Galle P, Melino G, et al. DeltaNp73beta is oncogenic in hepatocellular carcinoma by blocking apoptosis signaling via death receptors and mitochondria. Cell Cycle 2010; 9: 2629-39; PMID: 20581467; http://dx.doi.org/10.4161/cc.9.13.12110