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Volumn 14, Issue 24, 2015, Pages 3830-3841

Micro(mi) RNA-34a targets protein phosphatase (PP)1γ to regulate DNA damage tolerance

Author keywords

ATM; Cancer; Cancer therapy; DNA damage response; Ionising radiation; MiR 34a; MiRNA; P53; Protein phosphatase; Protein phosphatase 1

Indexed keywords

ATM PROTEIN; CYCLIN DEPENDENT KINASE 6; DNA; HISTONE H2AX; MICRORNA 34A; PHOSPHOPROTEIN PHOSPHATASE 1; PHOSPHOPROTEIN PHOSPHATASE 1GAMMA; PROTEIN P53; UNCLASSIFIED DRUG; 3' UNTRANSLATED REGION; MICRORNA; MIRN34 MICRORNA, HUMAN;

EID: 84964048255     PISSN: 15384101     EISSN: 15514005     Source Type: Journal    
DOI: 10.1080/15384101.2015.1064202     Document Type: Article
Times cited : (8)

References (44)
  • 1
    • 78649336706 scopus 로고    scopus 로고
    • The DNA damage response: Making it safe to play with knives
    • 20965415
    • Ciccia A, Elledge SJ. The DNA damage response: making it safe to play with knives. Mol Cell 2010; 40:179-204; PMID:20965415; http://dx.doi.org/10.1016/j-molcel.2010.09.019
    • (2010) Mol Cell , vol.40 , pp. 179-204
    • Ciccia, A.1    Elledge, S.J.2
  • 2
    • 70350504453 scopus 로고    scopus 로고
    • The DNA-damage response in human biology and disease
    • 19847258
    • Jackson SP, Bartek J. The DNA-damage response in human biology and disease. Nature 2009; 461:1071-8; PMID:19847258; http://dx.doi.org/10.1038/nature08467
    • (2009) Nature , vol.461 , pp. 1071-1078
    • Jackson, S.P.1    Bartek, J.2
  • 4
    • 74249123570 scopus 로고    scopus 로고
    • The miR-34 family in cancer and apo-ptosis
    • Hermeking H. The miR-34 family in cancer and apo-ptosis. Cell Death Differ 2010a; 17:193-9; http://dx.doi.org/10.1038/cdd.2009.56
    • (2010) Cell Death Differ , vol.17 , pp. 193-199
    • Hermeking, H.1
  • 9
    • 49249121155 scopus 로고    scopus 로고
    • Epigenetic silencing of micro-RNA-34b/c and B-cell translocation gene 4 is associated with CpG island methylation in colorectal cancer
    • 18519671
    • Toyota M, Suzuki H, Sasaki Y, Maruyama R, Imai K, Shinomura Y, Tokino T. Epigenetic silencing of micro-RNA-34b/c and B-cell translocation gene 4 is associated with CpG island methylation in colorectal cancer. Cancer Res 2008; 68:4123-32; PMID:18519671; http://dx.doi.org/10.1158/0008-5472.CAN-08-0325
    • (2008) Cancer Res , vol.68 , pp. 4123-4132
    • Toyota, M.1    Suzuki, H.2    Sasaki, Y.3    Maruyama, R.4    Imai, K.5    Shinomura, Y.6    Tokino, T.7
  • 10
    • 42049104107 scopus 로고    scopus 로고
    • Exploration of tumor-suppressive microRNAs silenced by DNA hypermethylation in oral cancer
    • 18381414
    • Kozaki K, Imoto I, Mogi S, Omura K, Inazawa J. Exploration of tumor-suppressive microRNAs silenced by DNA hypermethylation in oral cancer. Cancer Res 2008; 68:2094-105; PMID:18381414; http://dx.doi.org/10.1158/0008-5472.CAN-07-5194
    • (2008) Cancer Res , vol.68 , pp. 2094-2105
    • Kozaki, K.1    Imoto, I.2    Mogi, S.3    Omura, K.4    Inazawa, J.5
  • 12
    • 84916920091 scopus 로고    scopus 로고
    • Benassi MS. P53-Dependent Activation of microRNA-34a in Response to Etoposide-Induced DNA Damage in Osteosarcoma Cell Lines Not Impaired by Dominant Negative p53 Expression
    • 25490093
    • Novello C, Pazzaglia L, Conti A, Quattrini I, Pollino S, Perego P, Picci P, Benassi MS. p53-Dependent Activation of microRNA-34a in Response to Etoposide-Induced DNA Damage in Osteosarcoma Cell Lines Not Impaired by Dominant Negative p53 Expression. PLoS One 2014; 9:e114757; PMID:25490093; http://dx.doi.org/10.1371/journal.pone.0114757
    • (2014) Plos One , vol.9
    • Novello, C.1    Pazzaglia, L.2    Conti, A.3    Quattrini, I.4    Pollino, S.5    Perego, P.6    Picci, P.7
  • 13
    • 84907445475 scopus 로고    scopus 로고
    • Venkitaraman AR. P53 shapes genome-wide and cell type-specific changes in microRNA expression during the human DNA damage response
    • 25486198
    • Hattori H, Janky R, Nietfeld W, Aerts S, Madan Babu M, Venkitaraman AR. p53 shapes genome-wide and cell type-specific changes in microRNA expression during the human DNA damage response. Cell Cycle 2014; 13:2572-86; PMID:25486198; http://dx.doi.org/10.4161/15384101.2015.942209
    • (2014) Cell Cycle , vol.13 , pp. 2572-2586
    • Hattori, H.1    Janky, R.2    Nietfeld, W.3    Aerts, S.4    Madan Babu, M.5
  • 14
    • 33847199801 scopus 로고    scopus 로고
    • Emerging roles of nuclear protein phosphatases
    • 17318227
    • Moorhead GB, Trinkle-Mulcahy L, Ulke-Lemee A. Emerging roles of nuclear protein phosphatases. Nat Rev Mol Cell Biol 2007; 8:234-44; PMID:17318227; http://dx.doi.org/10.1038/nrm2126
    • (2007) Nat Rev Mol Cell Biol , vol.8 , pp. 234-244
    • Moorhead, G.B.1    Trinkle-Mulcahy, L.2    Ulke-Lemee, A.3
  • 15
    • 61649127812 scopus 로고    scopus 로고
    • From promiscuity to precision: Protein phosphatases get a makeover
    • 19285938
    • Virshup DM, Shenolikar S. From promiscuity to precision: protein phosphatases get a makeover. Mol Cell 2009; 33:537-45; PMID:19285938; http://dx.doi.org/10.1016/j.molcel.2009.02.015
    • (2009) Mol Cell , vol.33 , pp. 537-545
    • Virshup, D.M.1    Shenolikar, S.2
  • 16
    • 0037081563 scopus 로고    scopus 로고
    • Protein phosphatase 1-targeted in many directions
    • 11839776
    • Cohen PT. Protein phosphatase 1-targeted in many directions. J Cell Sci 2002; 115:241-56; PMID:11839776
    • (2002) J Cell Sci , vol.115 , pp. 241-256
    • Cohen, P.T.1
  • 17
    • 0032944179 scopus 로고    scopus 로고
    • Spermiogenesis is impaired in mice bearing a targeted mutation in the protein phosphatase 1c gamma gene
    • 9882500
    • Varmuza S, Jurisicova A, Okano K, Hudson J, Boekel-heide K, Shipp EB. Spermiogenesis is impaired in mice bearing a targeted mutation in the protein phosphatase 1c gamma gene. Dev Biol 1999; 205:98-110; PMID:9882500; http://dx.doi.org/10.1006/dbio.1998.9100
    • (1999) Dev Biol , vol.205 , pp. 98-110
    • Varmuza, S.1    Jurisicova, A.2    Okano, K.3    Hudson, J.4    Boekel-Heide, K.5    Shipp, E.B.6
  • 18
    • 77649178662 scopus 로고    scopus 로고
    • Repo-man controls a protein phosphatase 1-dependent threshold for DNA damage checkpoint activation
    • Peng A, Lewellyn AL, Schiemann WP, Maller JL. Repo-man controls a protein phosphatase 1-dependent threshold for DNA damage checkpoint activation. Curr Biol 2010a; 20:387-96; http://dx.doi.org/10.1016/j.cub.2010.01.020
    • (2010) Curr Biol , vol.20 , pp. 387-396
    • Peng, A.1    Lewellyn, A.L.2    Schiemann, W.P.3    Maller, J.L.4
  • 20
    • 79955666642 scopus 로고    scopus 로고
    • PP1/Repo-Man Dephosphorylates Mitotic Histone H3 at T3 and Regulates Chromosomal Aurora B Targeting
    • Qian JB, Lesage B, Beullens M, Van Eynde A, Bollen M. PP1/Repo-Man Dephosphorylates Mitotic Histone H3 at T3 and Regulates Chromosomal Aurora B Targeting. Curr Biol, 2011; 21:766-73; http://dx.doi.org/10.1016/j.cub.2011.03.047
    • (2011) Curr Biol , vol.21 , pp. 766-773
    • Qian, J.B.1    Lesage, B.2    Beullens, M.3    Van Eynde, A.4    Bollen, M.5
  • 21
    • 84865034968 scopus 로고    scopus 로고
    • Sds22 and Repo-Man stabilize chromosome segregation by counteracting Aurora B on anaphase kinetochores
    • 22801782
    • Wurzenberger C, Held M, Lampson MA, Poser I, Hyman AA, Gerlich DW. Sds22 and Repo-Man stabilize chromosome segregation by counteracting Aurora B on anaphase kinetochores. J Cell Biol 2012; 198:173-83; PMID:22801782; http://dx.doi.org/10.1083/jcb.201112112
    • (2012) J Cell Biol , vol.198 , pp. 173-183
    • Wurzenberger, C.1    Held, M.2    Lampson, M.A.3    Poser, I.4    Hyman, A.A.5    Gerlich, D.W.6
  • 22
    • 33644524404 scopus 로고    scopus 로고
    • Repo-Man recruits PP1 gamma to chromatin and is essential for cell viability
    • 16492807
    • Trinkle-Mulcahy L, Andersen J, Lam YW, Moorhead G, Mann M, Lamond AI. Repo-Man recruits PP1 gamma to chromatin and is essential for cell viability. J Cell Biol 2006; 172:679-92; PMID:16492807; http://dx.doi.org/10.1083/jcb.200508154
    • (2006) J Cell Biol , vol.172 , pp. 679-692
    • Trinkle-Mulcahy, L.1    Ersen, J.2    Lam, Y.W.3    Moorhead, G.4    Mann, M.5    Lamond, A.I.6
  • 23
    • 38549124383 scopus 로고    scopus 로고
    • The microRNA.Org resource: Targets and expression
    • 18158296
    • Betel D, Wilson M, Gabow A, Marks DS, Sander C. The microRNA.org resource: targets and expression. Nucleic Acids Res 2008; 36:D149-53; PMID:18158296; http://dx.doi.org/10.1093/nar/gkm995
    • (2008) Nucleic Acids Res , vol.36
    • Betel, D.1    Wilson, M.2    Gabow, A.3    Marks, D.S.4    Sander, C.5
  • 24
    • 33751520430 scopus 로고    scopus 로고
    • Natural selection on human microRNA binding sites inferred from SNP data
    • 17072316
    • Chen K, Rajewsky N. Natural selection on human microRNA binding sites inferred from SNP data. Nat Genet 2006; 38:1452-6; PMID:17072316; http://dx.doi.org/10.1038/ng1910
    • (2006) Nat Genet , vol.38 , pp. 1452-1456
    • Chen, K.1    Rajewsky, N.2
  • 25
    • 77955963884 scopus 로고    scopus 로고
    • Comprehensive modeling of microRNA targets predicts functional non-conserved and non-canonical sites
    • 20799968
    • Betel D, Koppal A, Agius P, Sander C, Leslie C. Comprehensive modeling of microRNA targets predicts functional non-conserved and non-canonical sites. Genome Biol 2010; 11:R90; PMID:20799968; http://dx.doi.org/10.1186/gb-2010-11-8-r90
    • (2010) Genome Biol , vol.11
    • Betel, D.1    Koppal, A.2    Agius, P.3    Sander, C.4    Leslie, C.5
  • 26
  • 27
    • 77649178662 scopus 로고    scopus 로고
    • Repo-man controls a protein phosphatase 1-dependent threshold for DNA damage checkpoint activation
    • Peng A, Lewellyn AL, Schiemann WP, Maller JL. Repo-man controls a protein phosphatase 1-dependent threshold for DNA damage checkpoint activation. Curr Biol 2010b; 20:387-96; http://dx.doi.org/10.1016/j.cub.2010.01.020
    • (2010) Curr Biol , vol.20 , pp. 387-396
    • Peng, A.1    Lewellyn, A.L.2    Schiemann, W.P.3    Maller, J.L.4
  • 28
    • 42049092138 scopus 로고    scopus 로고
    • Downregulation of CCND1 and CDK6 by miR-34a induces cell cycle arrest
    • 18406353
    • Sun F, Fu H, Liu Q, Tie Y, Zhu J, Xing R, Sun Z, Zheng X. Downregulation of CCND1 and CDK6 by miR-34a induces cell cycle arrest. FEBS Lett 2008; 582:1564-8; PMID:18406353; http://dx.doi.org/10.1016/j.febslet.2008.03.057
    • (2008) FEBS Lett , vol.582 , pp. 1564-1568
    • Sun, F.1    Fu, H.2    Liu, Q.3    Tie, Y.4    Zhu, J.5    Xing, R.6    Sun, Z.7    Zheng, X.8
  • 29
    • 78751477191 scopus 로고    scopus 로고
    • Gene silencing by micro-RNAs: Contributions of translational repression and mRNA decay
    • 21245828
    • Huntzinger E, Izaurralde E. Gene silencing by micro-RNAs: contributions of translational repression and mRNA decay. Nat Rev Genet 2011; 12:99-110; PMID:21245828; http://dx.doi.org/10.1038/nrg2936
    • (2011) Nat Rev Genet , vol.12 , pp. 99-110
    • Huntzinger, E.1    Izaurralde, E.2
  • 32
    • 0035545996 scopus 로고    scopus 로고
    • Mammalian G1- and S-phase checkpoints in response to DNA damage
    • 11698191
    • Bartek J, Lukas J. Mammalian G1- and S-phase checkpoints in response to DNA damage. Curr Opin Cell Biol 2001; 13:738-47; PMID:11698191; http://dx.doi.org/10.1016/S0955-0674(00)00280-5
    • (2001) Curr Opin Cell Biol , vol.13 , pp. 738-747
    • Bartek, J.1    Lukas, J.2
  • 33
    • 0343280013 scopus 로고    scopus 로고
    • A critical role for histone H2AX in recruitment of repair factors to nuclear foci after DNA damage
    • 10959836
    • Paull TT, Rogakou EP, Yamazaki V, Kirchgessner CU, Gellert M, Bonner WM. A critical role for histone H2AX in recruitment of repair factors to nuclear foci after DNA damage. Curr Biol 2000; 10:886-95; PMID:10959836; http://dx.doi.org/10.1016/S0960-9822(00)00610-2
    • (2000) Curr Biol , vol.10 , pp. 886-895
    • Paull, T.T.1    Rogakou, E.P.2    Yamazaki, V.3    Kirchgessner, C.U.4    Gellert, M.5    Bonner, W.M.6
  • 35
    • 0037472924 scopus 로고    scopus 로고
    • DNA damage activates ATM through intermolecular autophosphorylation and dimer dissociation
    • 12556884
    • Bakkenist CJ, Kastan MB. DNA damage activates ATM through intermolecular autophosphorylation and dimer dissociation. Nature 2003; 421:499-506; PMID:12556884; http://dx.doi.org/10.1038/nature01368
    • (2003) Nature , vol.421 , pp. 499-506
    • Bakkenist, C.J.1    Kastan, M.B.2
  • 37
    • 84874668158 scopus 로고    scopus 로고
    • The miR-99 family regulates the DNA damage response through its target SNF2H
    • 22525276
    • Mueller AC, Sun D, Dutta A. The miR-99 family regulates the DNA damage response through its target SNF2H. Oncogene 2013; 32:1164-72; PMID:22525276; http://dx.doi.org/10.1038/onc.2012.131
    • (2013) Oncogene , vol.32 , pp. 1164-1172
    • Mueller, A.C.1    Sun, D.2    Dutta, A.3
  • 38
    • 74249123570 scopus 로고    scopus 로고
    • The miR-34 family in cancer and apo-ptosis
    • Hermeking H. The miR-34 family in cancer and apo-ptosis. Cell Death Differ 2010b; 17:193-9; http://dx.doi.org/10.1038/cdd.2009.56
    • (2010) Cell Death Differ , vol.17 , pp. 193-199
    • Hermeking, H.1
  • 40
    • 31544456413 scopus 로고    scopus 로고
    • Insights into the kinetics of siRNA-mediated gene silencing from live-cell and live-animal bioluminescent imaging
    • 16410612
    • Bartlett DW, Davis ME. Insights into the kinetics of siRNA-mediated gene silencing from live-cell and live-animal bioluminescent imaging. Nucleic Acids Res 2006; 34:322-33; PMID:16410612; http://dx.doi.org/10.1093/nar/gkj439
    • (2006) Nucleic Acids Res , vol.34 , pp. 322-333
    • Bartlett, D.W.1    Davis, M.E.2
  • 41
    • 0033756308 scopus 로고    scopus 로고
    • Chromatin association of human origin recognition complex, cdc6, and mini-chromosome maintenance proteins during the cell cycle: Assembly of prereplication complexes in late mitosis
    • 11046155
    • Mendez J, Stillman B. Chromatin association of human origin recognition complex, cdc6, and mini-chromosome maintenance proteins during the cell cycle: assembly of prereplication complexes in late mitosis. Mol Cell Biol 2000; 20:8602-12; PMID:11046155; http://dx.doi.org/10.1128/MCB.20.22.8602-8612.2000
    • (2000) Mol Cell Biol , vol.20 , pp. 8602-8612
    • Mendez, J.1    Stillman, B.2
  • 43
    • 80052632447 scopus 로고    scopus 로고
    • MiR-34a targeting of Notch ligand delta-like 1 impairs CD15+/CD133+ tumor-propagating cells and supports neural differentiation in medulloblastoma
    • de Antonellis P, Medaglia C, Cusanelli E, Andolfo I, Liguori L, De Vita G, Carotenuto M, Bello A, Formig-gini F, Galeone A, et al. MiR-34a targeting of Notch ligand delta-like 1 impairs CD15+/CD133+ tumor-propagating cells and supports neural differentiation in medulloblastoma. PLoS One 2011; 6(9):e24584; http://dx.doi.org/10.1371/journal.pone.0024584
    • (2011) Plos One , vol.6 , Issue.9
    • De Antonellis, P.1    Medaglia, C.2    Cusanelli, E.3    Olfo, I.4    Liguori, L.5    De Vita, G.6    Carotenuto, M.7    Bello, A.8    Formig-Gini, F.9    Galeone, A.10


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