Glandular proteome identifies antiprotease cystatin c as a critical modulator of airway hydration and clearance

American Journal of Respiratory Cell and Molecular Biology

Volumn 54, Issue 4, 2016, Pages 469-481

  Evans, T Idil Apak ^a   Joo, Nam Soo ^b   Keiser, Nicholas W ^a   Yan, Ziying ^a   Tyler, Scott R ^a   Xie, Weiliang ^a   Zhang, Yulong ^a   Hsiao, Jordy J ^a   Cho, Hyung Ju ^b   Wright, Michael E ^a   Wine, Jeffrey J ^b   Engelhardt, John F ^a  

^a UNIVERSITY OF IOWA   (United States)

^b STANFORD UNIVERSITY   (United States)

Author keywords

Airway clearance; Cystic fibrosis; Cystic fibrosis transmembrane conductance regulator; Epithelial sodium channel; Submucosal glands

Indexed keywords

ANTITHROMBIN III; CATHEPSIN B; CATHEPSIN H; CATHEPSIN S; CYSTATIN C; CYSTEINE PROTEINASE; CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR; DIPEPTIDYL PEPTIDASE; EPITHELIAL SODIUM CHANNEL; MUCIN 5AC; PROTEINASE INHIBITOR; PROTEOME;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONFOCAL MICROSCOPY; CYSTIC FIBROSIS; ENZYME ACTIVITY; LUNG CLEARANCE; MUCOCILIARY CLEARANCE; NONHUMAN; PIG; SECRETION (PROCESS); TRACHEA; ANIMAL; BRONCHUS; FERRET; HEK293 CELL LINE; HUMAN; PATHOPHYSIOLOGY; PHYSIOLOGY;

ANIMALS; BRONCHI; CYSTATIN C; CYSTIC FIBROSIS; FERRETS; HEK293 CELLS; HUMANS; PROTEOME; TRACHEA;

EID: 84963758290     PISSN: 10441549     EISSN: 15354989     Source Type: Journal    
DOI: 10.1165/rcmb.2015-0090OC     Document Type: Article

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