Hyper-variability in circulating insulin, high fat feeding outcomes, and effects of reducing ins2 dosage in male ins1-null mice in a specific pathogen-free facility

PLoS ONE

Volumn 11, Issue 4, 2016, Pages

  Templeman, Nicole M ^a   Mehran, Arya E ^a   Johnson, James D ^a  

^a UNIVERSITY OF BRITISH COLUMBIA   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

CORTICOSTERONE; INSULIN; GLUCOSE BLOOD LEVEL; INS1 PROTEIN, MOUSE; INS2 PROTEIN, MOUSE;

ANIMAL EXPERIMENT; ARTICLE; BODY MASS; CONTROLLED STUDY; GENE; GENE DOSAGE; GENE INACTIVATION; GERMFREE MOUSE; GLUCOSE HOMEOSTASIS; HYPERINSULINEMIA; INS1 GENE; INS2 GENE; INSULIN RELEASE; INSULIN SENSITIVITY; LIPID DIET; MALE; MOUSE; NONHUMAN; OBESITY; WEIGHT GAIN; ADVERSE EFFECTS; ANALYSIS; ANIMAL; BLOOD; BODY COMPOSITION; C57BL MOUSE; FEMALE; GERMFREE ANIMAL; GLUCOSE BLOOD LEVEL; HYPERINSULINISM; INSULIN RESISTANCE; KNOCKOUT MOUSE; METABOLISM; PANCREAS ISLET; PATHOLOGY; PHYSIOLOGY; RAT; SECRETION (PROCESS);

ANIMALS; BLOOD GLUCOSE; BODY COMPOSITION; DIET, HIGH-FAT; FEMALE; HYPERINSULINISM; INSULIN; INSULIN RESISTANCE; ISLETS OF LANGERHANS; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; OBESITY; RATS; SPECIFIC PATHOGEN-FREE ORGANISMS;

EID: 84963748029     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0153280     Document Type: Article

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