Extranuclear estrogen receptor-α stimulates NeuroD1 binding to the insulin promoter and favors insulin synthesis

Proceedings of the National Academy of Sciences of the United States of America

Volumn 107, Issue 29, 2010, Pages 13057-13062

  Wong, Winifred P S ^a   Tiano, Joseph P ^a   Liu, Suhuan ^a   Hewitt, Sylvia C ^b   Le May, Cedric ^a   Dalle, Stéphane ^c   Katzenellenbogen, John A ^d   Katzenellenbogen, Benita S ^e   Korach, Kenneth S ^b   Mauvais Jarvis, Franck ^a  

^a NORTHWESTERN UNIVERSITY   (United States)

^b NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES   (United States)

^c INSERM   (France)

^d UNIVERSITY OF ILLINOIS AT URBANA CHAMPAIGN   (United States)

^e UNIVERSITY OF ILLINOIS AT URBANA CHAMPAIGN   (United States)

Author keywords

Diabetes; Islet

Indexed keywords

ESTRADIOL; ESTROGEN RECEPTOR ALPHA; ESTROGEN RECEPTOR BETA; INSULIN; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; NEUROGENIC DIFFERENTIATION FACTOR; PROTEIN TYROSINE KINASE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; ESTROGEN RESPONSIVE ELEMENT; GENETIC TRANSCRIPTION; INSULIN SYNTHESIS; MOUSE; NONHUMAN; NUCLEAR LOCALIZATION SIGNAL; PANCREAS ISLET BETA CELL; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION;

ANIMALS; BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTORS; CELL NUCLEUS; ESTRADIOL; ESTROGEN RECEPTOR ALPHA; GLUCOSE; INSULIN; ISLETS OF LANGERHANS; MICE; MICE, KNOCKOUT; MITOGEN-ACTIVATED PROTEIN KINASES; NERVE TISSUE PROTEINS; ORGAN SPECIFICITY; PROMOTER REGIONS, GENETIC; PROTEIN BINDING; PROTEIN TRANSPORT; RESPONSE ELEMENTS; SIGNAL TRANSDUCTION; SRC-FAMILY KINASES; TRANSCRIPTION, GENETIC;

MUS;

EID: 77955606282     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.0914501107     Document Type: Article

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