메뉴 건너뛰기




Volumn 34, Issue 8, 2016, Pages 627-637

Systems Biology Analysis of Heterocellular Signaling

Author keywords

cell signaling; cell cell communication; heterocellular; mass cytometry; phosphoproteomics; PTM; systems biology

Indexed keywords

BIOLOGY; CELL CULTURE; CELL PROLIFERATION; CELLS; CYTOLOGY; ISOTOPES; NEURODEGENERATIVE DISEASES; PULSE TIME MODULATION; SIGNALING;

EID: 84963632377     PISSN: 01677799     EISSN: 18793096     Source Type: Journal    
DOI: 10.1016/j.tibtech.2016.02.016     Document Type: Review
Times cited : (24)

References (75)
  • 1
    • 84887983173 scopus 로고    scopus 로고
    • An estimation of the number of cells in the human body
    • 1 Bianconi, E., et al. An estimation of the number of cells in the human body. Ann. Hum. Biol. 40 (2013), 463–471.
    • (2013) Ann. Hum. Biol. , vol.40 , pp. 463-471
    • Bianconi, E.1
  • 2
    • 34547623194 scopus 로고    scopus 로고
    • Common effector processing mediates cell-specific responses to stimuli
    • 2 Miller-Jensen, K., et al. Common effector processing mediates cell-specific responses to stimuli. Nature 448 (2007), 604–608.
    • (2007) Nature , vol.448 , pp. 604-608
    • Miller-Jensen, K.1
  • 3
    • 84956946896 scopus 로고    scopus 로고
    • Context-specific flow through the MEK/ERK module produces cell- and ligand-specific patterns of ERK single and double phosphorylation
    • 3 Iwamoto, N., et al. Context-specific flow through the MEK/ERK module produces cell- and ligand-specific patterns of ERK single and double phosphorylation. Sci. Signal., 9, 2016, ra13.
    • (2016) Sci. Signal. , vol.9 , pp. ra13
    • Iwamoto, N.1
  • 4
    • 0034676456 scopus 로고    scopus 로고
    • Feedback control of intercellular signalling in development
    • 4 Freeman, M., Feedback control of intercellular signalling in development. Nature 408 (2000), 313–319.
    • (2000) Nature , vol.408 , pp. 313-319
    • Freeman, M.1
  • 5
    • 77951620965 scopus 로고    scopus 로고
    • Spatial organization and signal transduction at intercellular junctions
    • 5 Manz, B.N., Groves, J.T., Spatial organization and signal transduction at intercellular junctions. Nat. Rev. Mol. Cell Biol. 11 (2010), 342–352.
    • (2010) Nat. Rev. Mol. Cell Biol. , vol.11 , pp. 342-352
    • Manz, B.N.1    Groves, J.T.2
  • 6
    • 0036500993 scopus 로고    scopus 로고
    • Systems biology: a brief overview
    • 6 Kitano, H., Systems biology: a brief overview. Science 295 (2002), 1662–1664.
    • (2002) Science , vol.295 , pp. 1662-1664
    • Kitano, H.1
  • 7
    • 7444253428 scopus 로고    scopus 로고
    • Systems biology and new technologies enable predictive and preventative medicine
    • 7 Hood, L., et al. Systems biology and new technologies enable predictive and preventative medicine. Science 306 (2004), 640–643.
    • (2004) Science , vol.306 , pp. 640-643
    • Hood, L.1
  • 8
    • 20444383859 scopus 로고    scopus 로고
    • Protein phosphorylation in signaling – 50 years and counting
    • 8 Pawson, T., Scott, J.D., Protein phosphorylation in signaling – 50 years and counting. Trends Biochem. Sci. 30 (2005), 286–290.
    • (2005) Trends Biochem. Sci. , vol.30 , pp. 286-290
    • Pawson, T.1    Scott, J.D.2
  • 9
    • 11144256544 scopus 로고    scopus 로고
    • Protein microarrays for multiplex analysis of signal transduction pathways
    • 9 Chan, S.M., et al. Protein microarrays for multiplex analysis of signal transduction pathways. Nat. Med. 10 (2004), 1390–1396.
    • (2004) Nat. Med. , vol.10 , pp. 1390-1396
    • Chan, S.M.1
  • 10
    • 84879637572 scopus 로고    scopus 로고
    • Integrated proteomic analysis of post-translational modifications by serial enrichment
    • 10 Mertins, P., et al. Integrated proteomic analysis of post-translational modifications by serial enrichment. Nat. Methods 10 (2013), 634–637.
    • (2013) Nat. Methods , vol.10 , pp. 634-637
    • Mertins, P.1
  • 11
    • 84890641204 scopus 로고    scopus 로고
    • The coming of age of phosphoproteomics – from large data sets to inference of protein functions
    • 11 Roux, P.P., Thibault, P., The coming of age of phosphoproteomics – from large data sets to inference of protein functions. Mol. Cell. Proteomics 12 (2013), 3453–3464.
    • (2013) Mol. Cell. Proteomics , vol.12 , pp. 3453-3464
    • Roux, P.P.1    Thibault, P.2
  • 12
    • 33750351769 scopus 로고    scopus 로고
    • Data-driven modelling of signal-transduction networks
    • 12 Janes, K.A., Yaffe, M.B., Data-driven modelling of signal-transduction networks. Nat. Rev. Mol. Cell Biol. 7 (2006), 820–828.
    • (2006) Nat. Rev. Mol. Cell Biol. , vol.7 , pp. 820-828
    • Janes, K.A.1    Yaffe, M.B.2
  • 13
    • 84878668031 scopus 로고    scopus 로고
    • Models of signalling networks – what cell biologists can gain from them and give to them
    • 13 Janes, K.A., Lauffenburger, D.A., Models of signalling networks – what cell biologists can gain from them and give to them. J. Cell Sci. 126 (2013), 1913–1921.
    • (2013) J. Cell Sci. , vol.126 , pp. 1913-1921
    • Janes, K.A.1    Lauffenburger, D.A.2
  • 14
    • 84929129370 scopus 로고    scopus 로고
    • Multidimensional proteomics for cell biology
    • 14 Larance, M., Lamond, A.I., Multidimensional proteomics for cell biology. Nat. Rev. Mol. Cell Biol. 16 (2015), 269–280.
    • (2015) Nat. Rev. Mol. Cell Biol. , vol.16 , pp. 269-280
    • Larance, M.1    Lamond, A.I.2
  • 15
    • 84896989445 scopus 로고    scopus 로고
    • A screen for short-range paracrine interactions
    • 15 Spencer, K.H., et al. A screen for short-range paracrine interactions. Integr. Biol. (Camb.) 6 (2014), 382–387.
    • (2014) Integr. Biol. (Camb.) , vol.6 , pp. 382-387
    • Spencer, K.H.1
  • 16
    • 46049089698 scopus 로고    scopus 로고
    • Biochemical purification of pseudopodia from migratory cells
    • 16 Wang, Y., Klemke, R.L., Biochemical purification of pseudopodia from migratory cells. Methods Mol. Biol. 370 (2007), 55–66.
    • (2007) Methods Mol. Biol. , vol.370 , pp. 55-66
    • Wang, Y.1    Klemke, R.L.2
  • 17
    • 84946730720 scopus 로고    scopus 로고
    • Global analysis of mRNA, translation, and protein localization: local translation is a key regulator of cell protrusions
    • 17 Mardakheh, F.K., et al. Global analysis of mRNA, translation, and protein localization: local translation is a key regulator of cell protrusions. Dev. Cell 35 (2015), 344–357.
    • (2015) Dev. Cell , vol.35 , pp. 344-357
    • Mardakheh, F.K.1
  • 18
    • 84887444879 scopus 로고    scopus 로고
    • Microenvironmental regulation of tumor progression and metastasis
    • 18 Quail, D.F., Joyce, J.A., Microenvironmental regulation of tumor progression and metastasis. Nat. Med. 19 (2013), 1423–1437.
    • (2013) Nat. Med. , vol.19 , pp. 1423-1437
    • Quail, D.F.1    Joyce, J.A.2
  • 19
    • 84875493834 scopus 로고    scopus 로고
    • Integrated view of genome structure and sequence of a single DNA molecule in a nanofluidic device
    • 19 Marie, R., et al. Integrated view of genome structure and sequence of a single DNA molecule in a nanofluidic device. Proc. Natl. Acad. Sci. U.S.A. 110 (2013), 4893–4898.
    • (2013) Proc. Natl. Acad. Sci. U.S.A. , vol.110 , pp. 4893-4898
    • Marie, R.1
  • 20
    • 84945973720 scopus 로고    scopus 로고
    • Cytometry-based single-cell analysis of intact epithelial signaling reveals MAPK activation divergent from TNF-α-induced apoptosis in vivo
    • 20 Simmons, A.J., et al. Cytometry-based single-cell analysis of intact epithelial signaling reveals MAPK activation divergent from TNF-α-induced apoptosis in vivo. Mol. Syst. Biol., 11, 2015, 835.
    • (2015) Mol. Syst. Biol. , vol.11 , pp. 835
    • Simmons, A.J.1
  • 21
    • 3242683662 scopus 로고    scopus 로고
    • Single cell profiling of potentiated phospho-protein networks in cancer cells
    • 21 Irish, J.M., et al. Single cell profiling of potentiated phospho-protein networks in cancer cells. Cell 118 (2004), 217–228.
    • (2004) Cell , vol.118 , pp. 217-228
    • Irish, J.M.1
  • 22
    • 68849103521 scopus 로고    scopus 로고
    • Mass cytometry: technique for real time single cell multitarget immunoassay based on inductively coupled plasma time-of-flight mass spectrometry
    • 22 Bandura, D.R., et al. Mass cytometry: technique for real time single cell multitarget immunoassay based on inductively coupled plasma time-of-flight mass spectrometry. Anal. Chem. 81 (2009), 6813–6822.
    • (2009) Anal. Chem. , vol.81 , pp. 6813-6822
    • Bandura, D.R.1
  • 23
    • 84921301669 scopus 로고    scopus 로고
    • Unraveling cell populations in tumors by single-cell mass cytometry
    • 23 Di Palma, S., Bodenmiller, B., Unraveling cell populations in tumors by single-cell mass cytometry. Curr. Opin. Biotechnol. 31 (2015), 122–129.
    • (2015) Curr. Opin. Biotechnol. , vol.31 , pp. 122-129
    • Di Palma, S.1    Bodenmiller, B.2
  • 24
    • 84866096861 scopus 로고    scopus 로고
    • Multiplexed mass cytometry profiling of cellular states perturbed by small-molecule regulators
    • 24 Bodenmiller, B., et al. Multiplexed mass cytometry profiling of cellular states perturbed by small-molecule regulators. Nat. Biotechnol. 30 (2012), 858–867.
    • (2012) Nat. Biotechnol. , vol.30 , pp. 858-867
    • Bodenmiller, B.1
  • 25
    • 84914127300 scopus 로고    scopus 로고
    • Systems biology. Conditional density-based analysis of T cell signaling in single-cell data
    • 25 Krishnaswamy, S., et al. Systems biology. Conditional density-based analysis of T cell signaling in single-cell data. Science, 346, 2014, 1250689.
    • (2014) Science , vol.346 , pp. 1250689
    • Krishnaswamy, S.1
  • 26
    • 84934442835 scopus 로고    scopus 로고
    • Data-driven phenotypic dissection of AML reveals progenitor-like cells that correlate with prognosis
    • 26 Levine, J.H., et al. Data-driven phenotypic dissection of AML reveals progenitor-like cells that correlate with prognosis. Cell 162 (2015), 184–197.
    • (2015) Cell , vol.162 , pp. 184-197
    • Levine, J.H.1
  • 27
    • 84942940566 scopus 로고    scopus 로고
    • Defining cell types and states with single-cell genomics
    • 27 Trapnell, C., Defining cell types and states with single-cell genomics. Genome Res. 25 (2015), 1491–1498.
    • (2015) Genome Res. , vol.25 , pp. 1491-1498
    • Trapnell, C.1
  • 28
    • 70349448552 scopus 로고    scopus 로고
    • Image analysis in high-content screening
    • 28 Niederlein, A., et al. Image analysis in high-content screening. Comb. Chem. High Throughput Screen. 12 (2009), 899–907.
    • (2009) Comb. Chem. High Throughput Screen. , vol.12 , pp. 899-907
    • Niederlein, A.1
  • 29
    • 77951975169 scopus 로고    scopus 로고
    • High content screening: seeing is believing
    • 29 Zanella, F., et al. High content screening: seeing is believing. Trends Biotechnol. 28 (2010), 237–245.
    • (2010) Trends Biotechnol. , vol.28 , pp. 237-245
    • Zanella, F.1
  • 30
    • 84880357794 scopus 로고    scopus 로고
    • Highly multiplexed single-cell analysis of formalin-fixed, paraffin-embedded cancer tissue
    • 30 Gerdes, M.J., et al. Highly multiplexed single-cell analysis of formalin-fixed, paraffin-embedded cancer tissue. Proc. Natl. Acad. Sci. U.S.A. 110 (2013), 11982–11987.
    • (2013) Proc. Natl. Acad. Sci. U.S.A. , vol.110 , pp. 11982-11987
    • Gerdes, M.J.1
  • 31
    • 84875902633 scopus 로고    scopus 로고
    • Quantum dot imaging platform for single-cell molecular profiling
    • 31 Zrazhevskiy, P., Gao, X., Quantum dot imaging platform for single-cell molecular profiling. Nat. Commun., 4, 2013, 1619.
    • (2013) Nat. Commun. , vol.4 , pp. 1619
    • Zrazhevskiy, P.1    Gao, X.2
  • 32
    • 84942133464 scopus 로고    scopus 로고
    • Highly multiplexed imaging of single cells using a high-throughput cyclic immunofluorescence method
    • 32 Lin, J.R., et al. Highly multiplexed imaging of single cells using a high-throughput cyclic immunofluorescence method. Nat. Commun., 6, 2015, 8390.
    • (2015) Nat. Commun. , vol.6 , pp. 8390
    • Lin, J.R.1
  • 33
    • 34250882643 scopus 로고    scopus 로고
    • Quantitative morphological signatures define local signaling networks regulating cell morphology
    • 33 Bakal, C., et al. Quantitative morphological signatures define local signaling networks regulating cell morphology. Science 316 (2007), 1753–1756.
    • (2007) Science , vol.316 , pp. 1753-1756
    • Bakal, C.1
  • 34
    • 84880328076 scopus 로고    scopus 로고
    • A screen for morphological complexity identifies regulators of switch-like transitions between discrete cell shapes
    • 34 Yin, Z., et al. A screen for morphological complexity identifies regulators of switch-like transitions between discrete cell shapes. Nat. Cell Biol. 15 (2013), 860–871.
    • (2013) Nat. Cell Biol. , vol.15 , pp. 860-871
    • Yin, Z.1
  • 35
    • 84958236911 scopus 로고    scopus 로고
    • A dynamical framework for the all-or-none G1/S transition
    • 35 Barr, A.R., et al. A dynamical framework for the all-or-none G1/S transition. Cell Systems 2 (2016), 27–37.
    • (2016) Cell Systems , vol.2 , pp. 27-37
    • Barr, A.R.1
  • 36
    • 84897954497 scopus 로고    scopus 로고
    • Highly multiplexed imaging of tumor tissues with subcellular resolution by mass cytometry
    • 36 Giesen, C., et al. Highly multiplexed imaging of tumor tissues with subcellular resolution by mass cytometry. Nat. Methods 11 (2014), 417–422.
    • (2014) Nat. Methods , vol.11 , pp. 417-422
    • Giesen, C.1
  • 37
    • 84898402897 scopus 로고    scopus 로고
    • Multiplexed ion beam imaging of human breast tumors
    • 37 Angelo, M., et al. Multiplexed ion beam imaging of human breast tumors. Nat. Med. 20 (2014), 436–442.
    • (2014) Nat. Med. , vol.20 , pp. 436-442
    • Angelo, M.1
  • 38
    • 84926342669 scopus 로고    scopus 로고
    • Immunohistochemistry and mass spectrometry for highly multiplexed cellular molecular imaging
    • 38 Levenson, R.M., et al. Immunohistochemistry and mass spectrometry for highly multiplexed cellular molecular imaging. Lab. Invest. 95 (2015), 397–405.
    • (2015) Lab. Invest. , vol.95 , pp. 397-405
    • Levenson, R.M.1
  • 39
    • 84930207118 scopus 로고    scopus 로고
    • Reproducibility crisis: blame it on the antibodies
    • 39 Baker, M., Reproducibility crisis: blame it on the antibodies. Nature 521 (2015), 274–276.
    • (2015) Nature , vol.521 , pp. 274-276
    • Baker, M.1
  • 40
    • 0037435030 scopus 로고    scopus 로고
    • Mass spectrometry-based proteomics
    • 40 Aebersold, R., Mann, M., Mass spectrometry-based proteomics. Nature 422 (2003), 198–207.
    • (2003) Nature , vol.422 , pp. 198-207
    • Aebersold, R.1    Mann, M.2
  • 41
    • 84890644637 scopus 로고    scopus 로고
    • Status of large-scale analysis of post-translational modifications by mass spectrometry
    • 41 Olsen, J.V., Mann, M., Status of large-scale analysis of post-translational modifications by mass spectrometry. Mol. Cell Proteomics 12 (2013), 3444–3452.
    • (2013) Mol. Cell Proteomics , vol.12 , pp. 3444-3452
    • Olsen, J.V.1    Mann, M.2
  • 42
    • 0036583926 scopus 로고    scopus 로고
    • Stable isotope labeling by amino acids in cell culture, SILAC, as a simple and accurate approach to expression proteomics
    • 42 Ong, S.E., et al. Stable isotope labeling by amino acids in cell culture, SILAC, as a simple and accurate approach to expression proteomics. Mol. Cell Proteomics 1 (2002), 376–386.
    • (2002) Mol. Cell Proteomics , vol.1 , pp. 376-386
    • Ong, S.E.1
  • 43
    • 72149101924 scopus 로고    scopus 로고
    • Cell-specific information processing in segregating populations of Eph receptor ephrin-expressing cells
    • 43 Jørgensen, C., et al. Cell-specific information processing in segregating populations of Eph receptor ephrin-expressing cells. Science 326 (2009), 1502–1509.
    • (2009) Science , vol.326 , pp. 1502-1509
    • Jørgensen, C.1
  • 44
    • 84961292183 scopus 로고    scopus 로고
    • Combinatorial proteomic analysis of intercellular signaling applied to the CD28 T-cell costimulatory receptor
    • 44 Tian, R., et al. Combinatorial proteomic analysis of intercellular signaling applied to the CD28 T-cell costimulatory receptor. Proc. Natl. Acad. Sci. U.S.A. 112 (2015), E1594–E1603.
    • (2015) Proc. Natl. Acad. Sci. U.S.A. , vol.112 , pp. E1594-E1603
    • Tian, R.1
  • 45
    • 84958535067 scopus 로고    scopus 로고
    • Phosphoproteomic analysis of interacting tumor and endothelial cells identifies regulatory mechanisms of transendothelial migration
    • 45 Locard-Paulet, M., et al. Phosphoproteomic analysis of interacting tumor and endothelial cells identifies regulatory mechanisms of transendothelial migration. Sci. Signal., 9, 2016, ra15.
    • (2016) Sci. Signal. , vol.9 , pp. ra15
    • Locard-Paulet, M.1
  • 46
    • 84906071018 scopus 로고    scopus 로고
    • PKA-regulated VASP phosphorylation promotes extrusion of transformed cells from the epithelium
    • 46 Anton, K.A., et al. PKA-regulated VASP phosphorylation promotes extrusion of transformed cells from the epithelium. J. Cell Sci. 127 (2014), 3425–3433.
    • (2014) J. Cell Sci. , vol.127 , pp. 3425-3433
    • Anton, K.A.1
  • 47
    • 78049334902 scopus 로고    scopus 로고
    • Trans-SILAC: sorting out the non-cell-autonomous proteome
    • 47 Rechavi, O., et al. Trans-SILAC: sorting out the non-cell-autonomous proteome. Nat. Methods 7 (2010), 923–927.
    • (2010) Nat. Methods , vol.7 , pp. 923-927
    • Rechavi, O.1
  • 48
    • 84927738514 scopus 로고    scopus 로고
    • Senescent cells communicate via intercellular protein transfer
    • 48 Biran, A., et al. Senescent cells communicate via intercellular protein transfer. Genes Dev. 29 (2015), 791–802.
    • (2015) Genes Dev. , vol.29 , pp. 791-802
    • Biran, A.1
  • 49
    • 84881475017 scopus 로고    scopus 로고
    • Cell-selective labeling using amino acid precursors for proteomic studies of multicellular environments
    • 49 Gauthier, N.P., et al. Cell-selective labeling using amino acid precursors for proteomic studies of multicellular environments. Nat. Methods 10 (2013), 768–773.
    • (2013) Nat. Methods , vol.10 , pp. 768-773
    • Gauthier, N.P.1
  • 50
    • 33947464968 scopus 로고
    • Racemization of lysine by Proteus vulgaris
    • 50 Huang, H.T., et al. Racemization of lysine by Proteus vulgaris. J. Am. Chem. Soc. 80 (1952), 1006–1007.
    • (1952) J. Am. Chem. Soc. , vol.80 , pp. 1006-1007
    • Huang, H.T.1
  • 51
    • 1842356696 scopus 로고
    • Diaminopimelic acid decarboxylase
    • 51 Dewey, D.L., Work, E., Diaminopimelic acid decarboxylase. Nature 169 (1952), 533–534.
    • (1952) Nature , vol.169 , pp. 533-534
    • Dewey, D.L.1    Work, E.2
  • 52
    • 84904106705 scopus 로고    scopus 로고
    • Cell-specific labeling enzymes for analysis of cell–cell communication in continuous co-culture
    • 52 Tape, C.J., et al. Cell-specific labeling enzymes for analysis of cell–cell communication in continuous co-culture. Mol. Cell Proteomics 13 (2014), 1866–1876.
    • (2014) Mol. Cell Proteomics , vol.13 , pp. 1866-1876
    • Tape, C.J.1
  • 53
    • 12444345515 scopus 로고    scopus 로고
    • Tandem mass tags: a novel quantification strategy for comparative analysis of complex protein mixtures by MS/MS
    • 53 Thompson, A., et al. Tandem mass tags: a novel quantification strategy for comparative analysis of complex protein mixtures by MS/MS. Anal. Chem. 75 (2003), 1895–1904.
    • (2003) Anal. Chem. , vol.75 , pp. 1895-1904
    • Thompson, A.1
  • 54
    • 84865718193 scopus 로고    scopus 로고
    • Increasing the multiplexing capacity of TMTs using reporter ion isotopologues with isobaric masses
    • 54 McAlister, G.C., et al. Increasing the multiplexing capacity of TMTs using reporter ion isotopologues with isobaric masses. Anal. Chem. 84 (2012), 7469–7478.
    • (2012) Anal. Chem. , vol.84 , pp. 7469-7478
    • McAlister, G.C.1
  • 55
    • 84910606524 scopus 로고    scopus 로고
    • Reproducible automated phosphopeptide enrichment using magnetic TiO2 and Ti-IMAC
    • 55 Tape, C.J., et al. Reproducible automated phosphopeptide enrichment using magnetic TiO2 and Ti-IMAC. Anal. Chem. 86 (2014), 10296–10302.
    • (2014) Anal. Chem. , vol.86 , pp. 10296-10302
    • Tape, C.J.1
  • 56
    • 84963502839 scopus 로고    scopus 로고
    • Oncogenic KRAS regulates tumor cell signaling via stromal reciprocation
    • 56 Tape, C.J., et al. Oncogenic KRAS regulates tumor cell signaling via stromal reciprocation. Cell, 2016, 10.1016/j.cell.2016.03.029.
    • (2016) Cell
    • Tape, C.J.1
  • 57
    • 80155124832 scopus 로고    scopus 로고
    • MS3 eliminates ratio distortion in isobaric multiplexed quantitative proteomics
    • 57 Ting, L., et al. MS3 eliminates ratio distortion in isobaric multiplexed quantitative proteomics. Nat. Methods 8 (2011), 937–940.
    • (2011) Nat. Methods , vol.8 , pp. 937-940
    • Ting, L.1
  • 58
    • 84875716859 scopus 로고    scopus 로고
    • Neutron-encoded mass signatures for multiplexed proteome quantification
    • 58 Hebert, A.S., et al. Neutron-encoded mass signatures for multiplexed proteome quantification. Nat. Methods 10 (2013), 332–334.
    • (2013) Nat. Methods , vol.10 , pp. 332-334
    • Hebert, A.S.1
  • 59
    • 84907221170 scopus 로고    scopus 로고
    • NeuCode labels for relative protein quantification
    • 59 Merrill, A.E., et al. NeuCode labels for relative protein quantification. Mol. Cell Proteomics 13 (2014), 2503–2512.
    • (2014) Mol. Cell Proteomics , vol.13 , pp. 2503-2512
    • Merrill, A.E.1
  • 60
    • 77956234847 scopus 로고    scopus 로고
    • Identification of biological tissues by rapid evaporative ionization mass spectrometry
    • 60 Balog, J., et al. Identification of biological tissues by rapid evaporative ionization mass spectrometry. Anal. Chem. 82 (2010), 7343–7350.
    • (2010) Anal. Chem. , vol.82 , pp. 7343-7350
    • Balog, J.1
  • 61
    • 84880525703 scopus 로고    scopus 로고
    • Intraoperative tissue identification using rapid evaporative ionization mass spectrometry
    • 61 Balog, J., et al. Intraoperative tissue identification using rapid evaporative ionization mass spectrometry. Sci. Transl. Med., 5, 2013, 194ra93.
    • (2013) Sci. Transl. Med. , vol.5 , pp. 194ra93
    • Balog, J.1
  • 62
    • 84944909550 scopus 로고    scopus 로고
    • Proteomic analysis of neurons microdissected from formalin-fixed, paraffin-embedded Alzheimer's disease brain tissue
    • 62 Drummond, E.S., et al. Proteomic analysis of neurons microdissected from formalin-fixed, paraffin-embedded Alzheimer's disease brain tissue. Sci. Rep., 5, 2015, 15456.
    • (2015) Sci. Rep. , vol.5 , pp. 15456
    • Drummond, E.S.1
  • 63
    • 84949104386 scopus 로고    scopus 로고
    • Cell type- and brain region-resolved mouse brain proteome
    • 63 Sharma, K., et al. Cell type- and brain region-resolved mouse brain proteome. Nat. Neurosci. 18 (2015), 1819–1831.
    • (2015) Nat. Neurosci. , vol.18 , pp. 1819-1831
    • Sharma, K.1
  • 64
    • 84901928401 scopus 로고    scopus 로고
    • Cross-species proteomics reveals specific modulation of signaling in cancer and stromal cells by phosphoinositide 3-kinase (PI3K) inhibitors
    • 64 Rajeeve, V., et al. Cross-species proteomics reveals specific modulation of signaling in cancer and stromal cells by phosphoinositide 3-kinase (PI3K) inhibitors. Mol. Cell Proteomics 13 (2014), 1457–1470.
    • (2014) Mol. Cell Proteomics , vol.13 , pp. 1457-1470
    • Rajeeve, V.1
  • 65
    • 33645736793 scopus 로고    scopus 로고
    • Genetically engineered models have advantages over xenografts for preclinical studies
    • Discussion, 3358-3359
    • 65 Becher, O.J., Holland, E.C., Genetically engineered models have advantages over xenografts for preclinical studies. Cancer Res. 66 (2006), 3355–3358 Discussion, 3358-3359.
    • (2006) Cancer Res. , vol.66 , pp. 3355-3358
    • Becher, O.J.1    Holland, E.C.2
  • 66
    • 34548217651 scopus 로고    scopus 로고
    • Maximizing mouse cancer models
    • 66 Frese, K.K., Tuveson, D.A., Maximizing mouse cancer models. Nat. Rev. Cancer 7 (2007), 645–658.
    • (2007) Nat. Rev. Cancer , vol.7 , pp. 645-658
    • Frese, K.K.1    Tuveson, D.A.2
  • 67
    • 84900339887 scopus 로고    scopus 로고
    • Proteome labeling and protein identification in specific tissues and at specific developmental stages in an animal
    • 67 Elliott, T.S., et al. Proteome labeling and protein identification in specific tissues and at specific developmental stages in an animal. Nat. Biotechnol. 32 (2014), 465–472.
    • (2014) Nat. Biotechnol. , vol.32 , pp. 465-472
    • Elliott, T.S.1
  • 68
    • 84956675430 scopus 로고    scopus 로고
    • Genetic code expansion in stable cell lines enables encoded chromatin modification
    • 68 Elsasser, S.J., et al. Genetic code expansion in stable cell lines enables encoded chromatin modification. Nat. Methods 13 (2016), 158–164.
    • (2016) Nat. Methods , vol.13 , pp. 158-164
    • Elsasser, S.J.1
  • 69
    • 80054768631 scopus 로고    scopus 로고
    • Extracting a cellular hierarchy from high-dimensional cytometry data with SPADE
    • 69 Qiu, P., et al. Extracting a cellular hierarchy from high-dimensional cytometry data with SPADE. Nat. Biotechnol. 29 (2011), 886–891.
    • (2011) Nat. Biotechnol. , vol.29 , pp. 886-891
    • Qiu, P.1
  • 70
    • 84880280631 scopus 로고    scopus 로고
    • viSNE enables visualization of high dimensional single-cell data and reveals phenotypic heterogeneity of leukemia
    • 70 Amir el, A.D., et al. viSNE enables visualization of high dimensional single-cell data and reveals phenotypic heterogeneity of leukemia. Nat. Biotechnol. 31 (2013), 545–552.
    • (2013) Nat. Biotechnol. , vol.31 , pp. 545-552
    • Amir el, A.D.1
  • 71
    • 84941362528 scopus 로고    scopus 로고
    • Automated analysis and classification of histological tissue features by multi-dimensional microscopic molecular profiling
    • 71 Riordan, D.P., et al. Automated analysis and classification of histological tissue features by multi-dimensional microscopic molecular profiling. PLoS ONE, 10, 2015, e0128975.
    • (2015) PLoS ONE , vol.10 , pp. e0128975
    • Riordan, D.P.1
  • 72
    • 34648834682 scopus 로고    scopus 로고
    • The third dimension bridges the gap between cell culture and live tissue
    • 72 Pampaloni, F., et al. The third dimension bridges the gap between cell culture and live tissue. Nat. Rev. Mol. Cell Biol. 8 (2007), 839–845.
    • (2007) Nat. Rev. Mol. Cell Biol. , vol.8 , pp. 839-845
    • Pampaloni, F.1
  • 73
    • 34547931078 scopus 로고    scopus 로고
    • Modeling tissue morphogenesis and cancer in 3D
    • 73 Yamada, K.M., Cukierman, E., Modeling tissue morphogenesis and cancer in 3D. Cell 130 (2007), 601–610.
    • (2007) Cell , vol.130 , pp. 601-610
    • Yamada, K.M.1    Cukierman, E.2
  • 74
    • 84904396621 scopus 로고    scopus 로고
    • Organogenesis in a dish: modeling development and disease using organoid technologies
    • 74 Lancaster, M.A., Knoblich, J.A., Organogenesis in a dish: modeling development and disease using organoid technologies. Science, 345, 2014, 1247125.
    • (2014) Science , vol.345 , pp. 1247125
    • Lancaster, M.A.1    Knoblich, J.A.2
  • 75
    • 79551583353 scopus 로고    scopus 로고
    • Engineering systems for the generation of patterned co-cultures for controlling cell–cell interactions
    • 75 Kaji, H., et al. Engineering systems for the generation of patterned co-cultures for controlling cell–cell interactions. Biochim. Biophys. Acta 1810 (2011), 239–250.
    • (2011) Biochim. Biophys. Acta , vol.1810 , pp. 239-250
    • Kaji, H.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.