-
1
-
-
14744303986
-
Mucosal adjuvants
-
Freytag, L.C. & Clements, J.D. Mucosal adjuvants. Vaccine 23, 1804-1813 (2005).
-
(2005)
Vaccine
, vol.23
, pp. 1804-1813
-
-
Freytag, L.C.1
Clements, J.D.2
-
2
-
-
0021260553
-
Generalized systemic and mucosal immunity in mice after mucosal stimulation with cholera toxin
-
Elson, C.O. & Ealding, W. Generalized systemic and mucosal immunity in mice after mucosal stimulation with cholera toxin. J. Immunol. 132, 2736-2741 (1984).
-
(1984)
J. Immunol.
, vol.132
, pp. 2736-2741
-
-
Elson, C.O.1
Ealding, W.2
-
3
-
-
0031741198
-
Intranasal immunization with cytotoxic T lymphocyte epitope peptide and mucosal adjuvant cholera toxin: Selective augmentation of peptide-presenting dendritic cells in nasal-mucosa-associated lymphoid tissue
-
Porgador, A., Staats, H.F., Itoh, Y. & Kelsall, B.L. Intranasal immunization with cytotoxic T lymphocyte epitope peptide and mucosal adjuvant cholera toxin: selective augmentation of peptide-presenting dendritic cells in nasal-mucosa-associated lymphoid tissue. Infect. Immun. 66, 5876-5881 (1998).
-
(1998)
Infect. Immun.
, vol.66
, pp. 5876-5881
-
-
Porgador, A.1
Staats, H.F.2
Itoh, Y.3
Kelsall, B.L.4
-
5
-
-
0026699224
-
The adjuvant effect of Vibrio cholerae and Escherichia coli heat-labile enterotoxins is linked to their ADP-ribosyltransferase activity
-
Lycke, N., Tsuji, T. & Holmgren, J. The adjuvant effect of Vibrio cholerae and Escherichia coli heat-labile enterotoxins is linked to their ADP-ribosyltransferase activity. Eur. J. Immunol. 22, 2277-2281 (1992).
-
(1992)
Eur. J. Immunol.
, vol.22
, pp. 2277-2281
-
-
Lycke, N.1
Tsuji, T.2
Holmgren, J.3
-
6
-
-
0033213958
-
Modulating dendritic cells to optimize mucosal immunization protocols
-
Williamson, E., Westrich, G.M. & Viney, J.L. Modulating dendritic cells to optimize mucosal immunization protocols. J. Immunol. 163, 3668-3675 (1999).
-
(1999)
J. Immunol.
, vol.163
, pp. 3668-3675
-
-
Williamson, E.1
Westrich, G.M.2
Viney, J.L.3
-
7
-
-
77953768395
-
H17 cells and protects against inhalation anthrax
-
H17 cells and protects against inhalation anthrax. Proc. Natl. Acad. Sci. USA 107, 10638-10643 (2010).
-
(2010)
Proc. Natl. Acad. Sci. USA
, vol.107
, pp. 10638-10643
-
-
Datta, S.K.1
-
8
-
-
0033081332
-
Cholera toxin suppresses interleukin (IL)-12 production and IL-12 receptor β1 and β2 chain expression
-
Braun, M.C., He, J., Wu, C.Y. & Kelsall, B.L. Cholera toxin suppresses interleukin (IL)-12 production and IL-12 receptor β1 and β2 chain expression. J. Exp. Med. 189, 541-552 (1999).
-
(1999)
J. Exp. Med.
, vol.189
, pp. 541-552
-
-
Braun, M.C.1
He, J.2
Wu, C.Y.3
Kelsall, B.L.4
-
9
-
-
0027183310
-
H2 cells in mucosa-associated tissues
-
H2 cells in mucosa-associated tissues. J. Exp. Med. 178, 1309-1320 (1993).
-
(1993)
J. Exp. Med.
, vol.178
, pp. 1309-1320
-
-
Xu-Amano, J.1
-
10
-
-
0007205169
-
H2-type responses for enhanced mucosal immunity
-
H2-type responses for enhanced mucosal immunity. Proc. Natl. Acad. Sci. USA 94, 5267-5272 (1997).
-
(1997)
Proc. Natl. Acad. Sci. USA
, vol.94
, pp. 5267-5272
-
-
Yamamoto, S.1
-
11
-
-
67449124387
-
+ dendritic cell differentiation by cAMP-mediated inhibition of IRF8 function
-
+ dendritic cell differentiation by cAMP-mediated inhibition of IRF8 function. J. Exp. Med. 206, 1227-1235 (2009).
-
(2009)
J. Exp. Med.
, vol.206
, pp. 1227-1235
-
-
La Sala, A.1
-
12
-
-
84863271877
-
H subsets
-
H subsets. J. Clin. Invest. 122, 963-973 (2012).
-
(2012)
J. Clin. Invest.
, vol.122
, pp. 963-973
-
-
Li, X.1
-
14
-
-
48549102504
-
NOD-like receptors (NLRs): Bona fide intracellular microbial sensors
-
Shaw, M.H., Reimer, T., Kim, Y.G. & Nuñez, G. NOD-like receptors (NLRs): bona fide intracellular microbial sensors. Curr. Opin. Immunol. 20, 377-382 (2008).
-
(2008)
Curr. Opin. Immunol.
, vol.20
, pp. 377-382
-
-
Shaw, M.H.1
Reimer, T.2
Kim, Y.G.3
Nuñez, G.4
-
15
-
-
0037458665
-
Host recognition of bacterial muramyl dipeptide mediated through NOD2. Implications for Crohn's disease
-
Inohara, N. et al. Host recognition of bacterial muramyl dipeptide mediated through NOD2. Implications for Crohn's disease. J. Biol. Chem. 278, 5509-5512 (2003).
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 5509-5512
-
-
Inohara, N.1
-
16
-
-
0012722659
-
Nod2 is a general sensor of peptidoglycan through muramyl dipeptide (MDP) detection
-
Girardin, S.E. et al. Nod2 is a general sensor of peptidoglycan through muramyl dipeptide (MDP) detection. J. Biol. Chem. 278, 8869-8872 (2003).
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 8869-8872
-
-
Girardin, S.E.1
-
17
-
-
33846936219
-
RICK (RIP2) mediates innate immune responses induced through Nod1 and Nod2 but not TLRs
-
Park, J.H. et al. RICK (RIP2) mediates innate immune responses induced through Nod1 and Nod2 but not TLRs. J. Immunol. 178, 2380-2386 (2007).
-
(2007)
J. Immunol.
, vol.178
, pp. 2380-2386
-
-
Park, J.H.1
-
18
-
-
38549084725
-
κB activation
-
κB activation. EMBO J. 27, 373-383 (2008).
-
(2008)
EMBO J
, vol.27
, pp. 373-383
-
-
Hasegawa, M.1
-
19
-
-
84916900222
-
Cutting edge: New chimeric NOD2-TLR2 adjuvant drastically increases vaccine immunogenicity
-
Pavot, V. et al. Cutting edge: new chimeric NOD2-TLR2 adjuvant drastically increases vaccine immunogenicity. J. Immunol. 193, 5781-5785 (2014).
-
(2014)
J. Immunol.
, vol.193
, pp. 5781-5785
-
-
Pavot, V.1
-
20
-
-
71849108536
-
H2 polarization of antigen-specific immunity
-
H2 polarization of antigen-specific immunity. J. Immunol. 181, 7925-7935 (2008).
-
(2008)
J. Immunol.
, vol.181
, pp. 7925-7935
-
-
Magalhaes, J.G.1
-
21
-
-
34247254780
-
Nod1-mediated innate immune recognition of peptidoglycan contributes to the onset of adaptive immunity
-
Fritz, J.H. et al. Nod1-mediated innate immune recognition of peptidoglycan contributes to the onset of adaptive immunity. Immunity 26, 445-459 (2007).
-
(2007)
Immunity
, vol.26
, pp. 445-459
-
-
Fritz, J.H.1
-
22
-
-
84936948783
-
Characterization of the nasopharyngeal microbiota in health and during rhinovirus challenge
-
Allen, E.K. et al. Characterization of the nasopharyngeal microbiota in health and during rhinovirus challenge. Microbiome 2, 22 (2014).
-
(2014)
Microbiome
, vol.2
, pp. 22
-
-
Allen, E.K.1
-
23
-
-
84871839728
-
MyD88: A critical adaptor protein in innate immunity signal transduction
-
Warner, N. & Núñez, G. MyD88: a critical adaptor protein in innate immunity signal transduction. J. Immunol. 190, 3-4 (2013).
-
(2013)
J. Immunol.
, vol.190
, pp. 3-4
-
-
Warner, N.1
Núñez, G.2
-
24
-
-
79956300649
-
Toll-like receptors and their cross-talk with other innate receptors in infection and immunity
-
Kawai, T. & Akira, S. Toll-like receptors and their cross-talk with other innate receptors in infection and immunity. Immunity 34, 637-650 (2011).
-
(2011)
Immunity
, vol.34
, pp. 637-650
-
-
Kawai, T.1
Akira, S.2
-
25
-
-
62849090439
-
Cytokine-secreting follicular T cells shape the antibody repertoire
-
Reinhardt, R.L., Liang, H.E. & Locksley, R.M. Cytokine-secreting follicular T cells shape the antibody repertoire. Nat. Immunol. 10, 385-393 (2009).
-
(2009)
Nat. Immunol.
, vol.10
, pp. 385-393
-
-
Reinhardt, R.L.1
Liang, H.E.2
Locksley, R.M.3
-
26
-
-
79952637807
-
FH) differentiation
-
FH) differentiation. PLoS One 6, e17739 (2011).
-
(2011)
PLoS One
, vol.6
-
-
Eto, D.1
-
27
-
-
84870283741
-
B and T cells collaborate in antiviral responses via IL-6, IL-21, and transcriptional activator and coactivator, Oct2 and OBF-1
-
Karnowski, A. et al. B and T cells collaborate in antiviral responses via IL-6, IL-21, and transcriptional activator and coactivator, Oct2 and OBF-1. J. Exp. Med. 209, 2049-2064 (2012).
-
(2012)
J. Exp. Med.
, vol.209
, pp. 2049-2064
-
-
Karnowski, A.1
-
28
-
-
0032480888
-
Epac is a Rap1 guanine-nucleotide exchange factor directly activated by cyclic AMP
-
de Rooij, J. et al. Epac is a Rap1 guanine-nucleotide exchange factor directly activated by cyclic AMP. Nature 396, 474-477 (1998).
-
(1998)
Nature
, vol.396
, pp. 474-477
-
-
De Rooij, J.1
-
29
-
-
84872506952
-
A genome-wide siRNA screen reveals positive and negative regulators of the NOD2 and NF-κB signaling pathways
-
Warner, N. et al. A genome-wide siRNA screen reveals positive and negative regulators of the NOD2 and NF-κB signaling pathways. Sci. Signal. 6, rs3 (2013).
-
(2013)
Sci. Signal
, vol.6
, pp. rs3
-
-
Warner, N.1
-
30
-
-
53349173070
-
Specific microbiota direct the differentiation of IL-17-producing T helper cells in the mucosa of the small intestine
-
Ivanov, I.I. et al. Specific microbiota direct the differentiation of IL-17-producing T helper cells in the mucosa of the small intestine. Cell Host Microbe 4, 337-349 (2008).
-
(2008)
Cell Host Microbe
, vol.4
, pp. 337-349
-
-
Ivanov, I.I.1
-
31
-
-
84856083002
-
Cross-talk between B lymphocytes, microbiota and the intestinal epithelium governs immunity versus metabolism in the gut
-
Shulzhenko, N. et al. Cross-talk between B lymphocytes, microbiota and the intestinal epithelium governs immunity versus metabolism in the gut. Nat. Med. 17, 1585-1593 (2011).
-
(2011)
Nat. Med.
, vol.17
, pp. 1585-1593
-
-
Shulzhenko, N.1
-
32
-
-
84864311450
-
Commensal bacteria calibrate the activation threshold of innate antiviral immunity
-
Abt, M.C. et al. Commensal bacteria calibrate the activation threshold of innate antiviral immunity. Immunity 37, 158-170 (2012).
-
(2012)
Immunity
, vol.37
, pp. 158-170
-
-
Abt, M.C.1
-
33
-
-
44449106055
-
A microbial symbiosis factor prevents intestinal inflammatory disease
-
Mazmanian, S.K., Round, J.L. & Kasper, D.L. A microbial symbiosis factor prevents intestinal inflammatory disease. Nature 453, 620-625 (2008).
-
(2008)
Nature
, vol.453
, pp. 620-625
-
-
Mazmanian, S.K.1
Round, J.L.2
Kasper, D.L.3
-
34
-
-
0016200846
-
Minimal structural requirements for adjuvant activity of bacterial peptidoglycan derivatives
-
Ellouz, F., Adam, A., Ciorbaru, R. & Lederer, E. Minimal structural requirements for adjuvant activity of bacterial peptidoglycan derivatives. Biochem. Biophys. Res. Commun. 59, 1317-1325 (1974).
-
(1974)
Biochem. Biophys. Res. Commun.
, vol.59
, pp. 1317-1325
-
-
Ellouz, F.1
Adam, A.2
Ciorbaru, R.3
Lederer, E.4
-
35
-
-
80052556040
-
Nucleotide-oligomerization-domain-containing proteins instruct T cell helper type 2 immunity through stromal activation
-
Magalhaes, J.G. et al. Nucleotide-oligomerization-domain-containing proteins instruct T cell helper type 2 immunity through stromal activation. Proc. Natl. Acad. Sci. USA 108, 14896-14901 (2011).
-
(2011)
Proc. Natl. Acad. Sci. USA
, vol.108
, pp. 14896-14901
-
-
Magalhaes, J.G.1
-
36
-
-
78649824846
-
H2-driven allergic inflammation
-
H2-driven allergic inflammation. J. Allergy Clin. Immunol. 126, 1284-1293.e10 (2010).
-
(2010)
J. Allergy Clin. Immunol.
, vol.126
, pp. 1284-1293.e10
-
-
Duan, W.1
-
37
-
-
70450265288
-
+ T cells to the T follicular helper (TFH ) cell lineage is induced by IL-12
-
+ T cells to the T follicular helper (TFH ) cell lineage is induced by IL-12. Immunol. Cell Biol. 87, 590-600 (2009).
-
(2009)
Immunol. Cell Biol.
, vol.87
, pp. 590-600
-
-
Ma, C.S.1
-
38
-
-
68249158536
-
Human dendritic cells induce the differentiation of interleukin-21-producing T follicular helper-like cells through interleukin-12
-
Schmitt, N. et al. Human dendritic cells induce the differentiation of interleukin-21-producing T follicular helper-like cells through interleukin-12. Immunity 31, 158-169 (2009).
-
(2009)
Immunity
, vol.31
, pp. 158-169
-
-
Schmitt, N.1
-
39
-
-
77956990501
-
Performance of rotavirus vaccines in developed and developing countries
-
Jiang, V., Jiang, B., Tate, J., Parashar, U.D. & Patel, M.M. Performance of rotavirus vaccines in developed and developing countries. Hum. Vaccin. 6, 532-542 (2010).
-
(2010)
Hum. Vaccin
, vol.6
, pp. 532-542
-
-
Jiang, V.1
Jiang, B.2
Tate, J.3
Parashar, U.D.4
Patel, M.M.5
-
40
-
-
77957375946
-
Immunogenicity and efficacy of oral vaccines in developing countries: Lessons from a live cholera vaccine
-
Levine, M.M. Immunogenicity and efficacy of oral vaccines in developing countries: lessons from a live cholera vaccine. BMC Biol. 8, 129 (2010).
-
(2010)
BMC Biol.
, vol.8
, pp. 129
-
-
Levine, M.M.1
-
41
-
-
84864721137
-
Understanding reduced rotavirus vaccine efficacy in low socioeconomic settings
-
Lopman, B.A. et al. Understanding reduced rotavirus vaccine efficacy in low socioeconomic settings. PLoS One 7, e41720 (2012).
-
(2012)
PLoS One
, vol.7
-
-
Lopman, B.A.1
-
42
-
-
70349314774
-
Mucosal immunity after vaccination with monovalent and trivalent oral poliovirus vaccine in India
-
Grassly, N.C. et al. Mucosal immunity after vaccination with monovalent and trivalent oral poliovirus vaccine in India. J. Infect. Dis. 200, 794-801 (2009).
-
(2009)
J. Infect. Dis.
, vol.200
, pp. 794-801
-
-
Grassly, N.C.1
-
43
-
-
84868231122
-
Comparison of immune responses to the O-specific polysaccharide and lipopolysaccharide of Vibrio cholerae O1 in Bangladeshi adult patients with cholera
-
Johnson, R.A. et al. Comparison of immune responses to the O-specific polysaccharide and lipopolysaccharide of Vibrio cholerae O1 in Bangladeshi adult patients with cholera. Clin. Vaccine Immunol. 19, 1712-1721 (2012).
-
(2012)
Clin. Vaccine Immunol.
, vol.19
, pp. 1712-1721
-
-
Johnson, R.A.1
-
44
-
-
79961120436
-
Comparison of memory B cell, antibody-secreting cell and plasma antibody responses in young children, older children and adults with infection caused by Vibrio cholerae O1 El Tor Ogawa in Bangladesh
-
Leung, D.T. et al. Comparison of memory B cell, antibody-secreting cell and plasma antibody responses in young children, older children and adults with infection caused by Vibrio cholerae O1 El Tor Ogawa in Bangladesh. Clin. Vaccine Immunol. 18, 1317-1325 (2011).
-
(2011)
Clin. Vaccine Immunol.
, vol.18
, pp. 1317-1325
-
-
Leung, D.T.1
-
45
-
-
84862141704
-
Human gut microbiome viewed across age and geography
-
Yatsunenko, T. et al. Human gut microbiome viewed across age and geography. Nature 486, 222-227 (2012).
-
(2012)
Nature
, vol.486
, pp. 222-227
-
-
Yatsunenko, T.1
-
46
-
-
84861879505
-
Environmental enteropathy: Critical implications of a poorly understood condition
-
Korpe, P.S. & Petri, W.A. Jr. Environmental enteropathy: critical implications of a poorly understood condition. Trends Mol. Med. 18, 328-336 (2012).
-
(2012)
Trends Mol. Med.
, vol.18
, pp. 328-336
-
-
Korpe, P.S.1
Petri, W.A.2
-
47
-
-
84883405129
-
Divergent immunomodulating effects of probiotics on T cell responses to oral attenuated human rotavirus vaccine and virulent human rotavirus infection in a neonatal gnotobiotic piglet disease model
-
Chattha, K.S., Vlasova, A.N., Kandasamy, S., Rajashekara, G. & Saif, L.J. Divergent immunomodulating effects of probiotics on T cell responses to oral attenuated human rotavirus vaccine and virulent human rotavirus infection in a neonatal gnotobiotic piglet disease model. J. Immunol. 191, 2446-2456 (2013).
-
(2013)
J. Immunol.
, vol.191
, pp. 2446-2456
-
-
Chattha, K.S.1
Vlasova, A.N.2
Kandasamy, S.3
Rajashekara, G.4
Saif, L.J.5
-
48
-
-
84908003512
-
TLR5-mediated sensing of gut microbiota is necessary for antibody responses to seasonal influenza vaccination
-
Oh, J.Z. et al. TLR5-mediated sensing of gut microbiota is necessary for antibody responses to seasonal influenza vaccination. Immunity 41, 478-492 (2014).
-
(2014)
Immunity
, vol.41
, pp. 478-492
-
-
Oh, J.Z.1
-
49
-
-
65549119322
-
Suppression of allergic diarrhea in murine ovalbumin-induced allergic diarrhea model by PG102, a water-soluble extract prepared from Actinidia arguta
-
Kim, D. et al. Suppression of allergic diarrhea in murine ovalbumin-induced allergic diarrhea model by PG102, a water-soluble extract prepared from Actinidia arguta. Int. Arch. Allergy Immunol. 150, 164-171 (2009).
-
(2009)
Int. Arch. Allergy Immunol.
, vol.150
, pp. 164-171
-
-
Kim, D.1
-
50
-
-
0030701953
-
Nasal lymphoid tissue (NALT) as a mucosal immune-inductive site
-
Wu, H.Y., Nguyen, H.H. & Russell, M.W. Nasal lymphoid tissue (NALT) as a mucosal immune-inductive site. Scand. J. Immunol. 46, 506-513 (1997).
-
(1997)
Scand. J. Immunol.
, vol.46
, pp. 506-513
-
-
Wu, H.Y.1
Nguyen, H.H.2
Russell, M.W.3
-
51
-
-
70249110860
-
Cutting edge: TNF-α mediates sensitization to ATP and silica via the NLRP3 inflammasome in the absence of microbial stimulation
-
Franchi, L., Eigenbrod, T. & Núñez, G. Cutting edge: TNF-α mediates sensitization to ATP and silica via the NLRP3 inflammasome in the absence of microbial stimulation. J. Immunol. 183, 792-796 (2009).
-
(2009)
J. Immunol.
, vol.183
, pp. 792-796
-
-
Franchi, L.1
Eigenbrod, T.2
Núñez, G.3
-
52
-
-
76749110853
-
Transitions in oral and intestinal microflora composition and innate-immune-receptor-dependent stimulation during mouse development
-
Hasegawa, M. et al. Transitions in oral and intestinal microflora composition and innate-immune-receptor-dependent stimulation during mouse development. Infect. Immun. 78, 639-650 (2010).
-
(2010)
Infect. Immun.
, vol.78
, pp. 639-650
-
-
Hasegawa, M.1
-
53
-
-
78649895980
-
Vancomycin-resistant Enterococcus domination of intestinal microbiota is enabled by antibiotic treatment in mice and precedes bloodstream invasion in humans
-
Ubeda, C. et al. Vancomycin-resistant Enterococcus domination of intestinal microbiota is enabled by antibiotic treatment in mice and precedes bloodstream invasion in humans. J. Clin. Invest. 120, 4332-4341 (2010).
-
(2010)
J. Clin. Invest.
, vol.120
, pp. 4332-4341
-
-
Ubeda, C.1
|