SIRT3 is crucial for maintaining skeletal muscle insulin action and protects against severe insulin resistance in high-fat-fed mice

Diabetes

Volumn 64, Issue 9, 2015, Pages 3081-3092

  Lantier, Louise ^a,b   Williams, Ashley S ^a   Williams, Ian M ^a   Yang, Karen K ^a   Bracy, Deanna P ^a   Goelzer, Mickael ^a   James, Freyja D ^a   Gius, David ^c   Wasserman, David H ^a,b  

^a VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b VANDERBILT UNIVERSITY   (United States)

^c NORTHWESTERN UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

FATTY ACID; GLUCOSE; GLUCOSE TRANSPORTER 4; INSULIN; MITOCHONDRIAL PROTEIN; SIRTUIN 3; HEXOKINASE; SIRT3 PROTEIN, MOUSE;

ARTICLE; CITRIC ACID CYCLE; CONTROLLED STUDY; ENERGY; GENE DELETION; GLUCOSE TRANSPORT; HOMEOSTASIS; HYPERINSULINEMIC-EUGLYCEMIC CLAMP TECHNIQUE; IMMUNOHISTOCHEMISTRY; IMMUNOPRECIPITATION; INSULIN RESISTANCE; INSULIN SENSITIVITY; LIPID DIET; MALE; MITOCHONDRIAL RESPIRATION; MITOCHONDRION; MOUSE; MUSCLE CELL; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN ACETYLATION; RESPIROMETRY; SKELETAL MUSCLE; WESTERN BLOTTING; ACETYLATION; ANIMAL; GENETICS; GLUCOSE CLAMP TECHNIQUE; GLUCOSE INTOLERANCE; KNOCKOUT MOUSE; METABOLISM; PHYSIOLOGY;

ACETYLATION; ANIMALS; DIET, HIGH-FAT; GLUCOSE CLAMP TECHNIQUE; GLUCOSE INTOLERANCE; HEXOKINASE; INSULIN; INSULIN RESISTANCE; MICE; MICE, KNOCKOUT; MITOCHONDRIA; MUSCLE FIBERS, SKELETAL; MUSCLE, SKELETAL; SIRTUIN 3;

EID: 84962802960     PISSN: 00121797     EISSN: 1939327X     Source Type: Journal    
DOI: 10.2337/db14-1810     Document Type: Article

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