Proton radiotherapy in the treatment of lung cancer

Translational Cancer Research

Volumn 1, Issue 4, 2012, Pages 264-270

  Skinner, Heath Devin ^a   Komaki, Ritsuko ^a  

^a UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

Author keywords

Lung cancer; Protons; Radiation therapy

Indexed keywords

CANCER THERAPY; HUMAN; LUNG CANCER; PROTON RADIATION; PROTON THERAPY; RADIATION PHYSICS; RANDOMIZED CONTROLLED TRIAL (TOPIC); REVIEW; UNITED STATES;

EID: 84962683387     PISSN: 2218676X     EISSN: 22196803     Source Type: Journal    
DOI: 10.3978/j.issn.2218-676X.2012.12.02     Document Type: Review

References (35)

1. Bragg W. On the ionization of various gasses by the alpha particles of radium. Proc Phys Soc 1907;20:523-50.
2. Paganetti H, Niemierko A, Ancukiewicz M, et al. Relative biological effectiveness (RBE) values for proton beam therapy. Int J Radiat Oncol Biol Phys 2002;53:407-21.
3. International Commission on Radiation Units and Measurements. Prescribing, recording, and reporting proton-beam therapy (ICRU report 78). Bethesda, MD.
4. Wouters BG, Lam GK, Oelfke U, et al. Measurements of relative biological effectiveness of the 70 MeV proton beam at TRIUMF using Chinese hamster V79 cells and the high-precision cell sorter assay. Radiat Res 1996;146:159-70.
5. Bettega D, Calzolari P, Chauvel P, et al. Radiobiological studies on the 65 MeV therapeutic proton beam at Nice using human tumour cells. Int J Radiat Biol 2000;76:1297-303.
6. Tang JT, Inoue T, Inoue T, et al. Comparison of radiobiological effective depths in 65-MeV modulated proton beams. Br J Cancer 1997;76:220-5.
7. Courdi A, Brassart N, Hérault J, et al. The depth-dependent radiation response of human melanoma cells exposed to 65 MeV protons. Br J Radiol 1994;67:800-4.
8. Matsuura T, Egashira Y, Nishio T, et al. Apparent absence of a proton beam dose rate effect and possible differences in RBE between Bragg peak and plateau. Med Phys 2010;37:5376-81.
9. Frese MC, Wilkens JJ, Huber PE, et al. Application of constant vs. variable relative biological effectiveness in treatment planning of intensity-modulated proton therapy. Int J Radiat Oncol Biol Phys 2011;79:80-8.
10. Carabe A, Moteabbed M, Depauw N, et al. Range uncertainty in proton therapy due to variable biological effectiveness. Phys Med Biol 2012;57:1159-72.
11. Jones B, Underwood TS, Dale RG. The potential impact of relative biological effectiveness uncertainty on charged particle treatment prescriptions. Br J Radiol 2011;84:S61-9.
12. O'Rourke N, Roqué I, Figuls M, et al. Concurrent chemoradiotherapy in non-small cell lung cancer. Cochrane Database Syst Rev 2010;(6):CD002140.
13. Partridge M, Ramos M, Sardaro A, et al. Dose escalation for non-small cell lung cancer: analysis and modelling of published literature. Radiother Oncol 2011;99:6-11.
14. Bradley JD, Paulus R, Komaki R, et al. A randomized phase III comparison of standard-dose (60 Gy) versus high-dose (74 Gy) conformal chemoradiotherapy +/-cetuximab for stage IIIa/IIIb non-small cell lung cancer: Preliminary findings on radiation dose in RTOG 0617. Int J Radiat Oncol Biol Phys 2011;81: abstr LBA2.
15. Chang JY, Zhang X, Wang X, et al. Significant reduction of normal tissue dose by proton radiotherapy compared with three-dimensional conformal or intensity-modulated radiation therapy in Stage I or Stage III non-small-cell lung cancer. Int J Radiat Oncol Biol Phys 2006;65:1087-96.
16. Lee CH, Tait D, Nahum AE, et al. Comparison of proton therapy and conformal X-ray therapy in non-small cell lung cancer (NSCLC). Br J Radiol 1999;72:1078-84.
17. Nichols RC, Huh SN, Henderson RH, et al. Proton radiation therapy offers reduced normal lung and bone marrow exposure for patients receiving dose-escalated radiation therapy for unresectable stage iii non-small-cell lung cancer: a dosimetric study. Clin Lung Cancer 2011;12:252-7.
18. Macdonald OK, Kruse JJ, Miller JM, et al. Proton beam radiotherapy versus three-dimensional conformal stereotactic body radiotherapy in primary peripheral, early-stage non-small-cell lung carcinoma: a comparative dosimetric analysis. Int J Radiat Oncol Biol Phys 2009;75:950-8.
19. Hoppe BS, Huh S, Flampouri S, et al. Double-scattered proton-based stereotactic body radiotherapy for stage I lung cancer: a dosimetric comparison with photon-based stereotactic body radiotherapy. Radiother Oncol 2010;97:425-30.
20. Wang C, Nakayama H, Sugahara S, et al. Comparisons of dose-volume histograms for proton-beam versus 3-D conformal x-ray therapy in patients with stage I non-small cell lung cancer. Strahlenther Onkol 2009;185:231-4.
21. Seco J, Panahandeh HR, Westover K, et al. Treatment of non-small cell lung cancer patients with proton beam-based stereotactic body radiotherapy: dosimetric comparison with photon plans highlights importance of range uncertainty. Int J Radiat Oncol Biol Phys 2012;83:354-61.
22. Zhang X, Li Y, Pan X, et al. Intensity-modulated proton therapy reduces the dose to normal tissue compared with intensity-modulated radiation therapy or passive scattering proton therapy and enables individualized radical radiotherapy for extensive stage IIIB non-small-cell lung cancer: a virtual clinical study. Int J Radiat Oncol Biol Phys 2010;77:357-66.
23. Bush DA, Slater JD, Bonnet R, et al. Proton-beam radiotherapy for early-stage lung cancer. Chest 1999;116:1313-9.
24. Bush DA, Slater JD, Shin BB, et al. Hypofractionated proton beam radiotherapy for stage I lung cancer. Chest 2004;126:1198-203.
25. Iwata H, Murakami M, Demizu Y, et al. High-dose proton therapy and carbon-ion therapy for stage I nonsmall cell lung cancer. Cancer 2010;116:2476-85.
26. Nihei K, Ogino T, Ishikura S, et al. High-dose proton beam therapy for Stage I non-small-cell lung cancer. Int J Radiat Oncol Biol Phys 2006;65:107-11.
27. Chang JY, Komaki R, Wen HY, et al. Toxicity and patterns of failure of adaptive/ablative proton therapy for early-stage, medically inoperable non-small cell lung cancer. Int J Radiat Oncol Biol Phys 2011;80:1350-7.
28. Sejpal S, Komaki R, Tsao A, et al. Early findings on toxicity of proton beam therapy with concurrent chemotherapy for nonsmall cell lung cancer. Cancer 2011;117:3004-13.
29. Chang JY, Komaki R, Lu C, et al. Phase 2 study of high-dose proton therapy with concurrent chemotherapy for unresectable stage III nonsmall cell lung cancer. Cancer 2011;117:4707-13.
30. Liao Z, Lin SH, Cox JD. Status of particle therapy for lung cancer. Acta Oncol 2011;50:745-56.
31. Mohan R, Zhang X, Matney J, et al. IMRT vs. passively scattered proton therapy (PSPT) for locally advanced non-small cell lung cancer (LA NSCLC) randomized trial-is there equipoise? Int J Radiat Oncol Biol Phys 2010;78:S201-2.
32. Schippers JM, Lomax AJ. Emerging technologies in proton therapy. Acta Oncol 2011;50:838-50.
33. Brenner DJ, Hall EJ. Secondary neutrons in clinical proton radiotherapy: a charged issue. Radiother Oncol 2008;86:165-70.
34. Paganetti H, Bortfeld T, Delaney TF. Neutron dose in proton radiation therapy: in regard to Eric J. Hall (Int J Radiat Oncol Biol Phys 2006;65:1-7). Int J Radiat Oncol Biol Phys 2006;66:1594-5; author reply 1595.
35. Grutters JP, Pijls-Johannesma M, Ruysscher DD, et al. The cost-effectiveness of particle therapy in non-small cell lung cancer: exploring decision uncertainty and areas for future research. Cancer Treat Rev 2010;36:468-76.