-
1
-
-
84920837701
-
Cancer statistics, 2015
-
Siegel RL, Miller KD, Jemal A. Cancer statistics, 2015. CA Cancer J Clin. 2015;65(1):5-29.
-
(2015)
CA Cancer J Clin
, vol.65
, Issue.1
, pp. 5-29
-
-
Siegel, R.L.1
Miller, K.D.2
Jemal, A.3
-
2
-
-
77955080349
-
New therapies for castration-resistant prostate cancer
-
Longo DL. New therapies for castration-resistant prostate cancer. N Engl J Med. 2010;363(5):479-81.
-
(2010)
N Engl J Med
, vol.363
, Issue.5
, pp. 479-481
-
-
Longo, D.L.1
-
3
-
-
84872078210
-
COU-AA-302 Investigators. Abiraterone in metastatic prostate cancer without previous chemotherapy
-
Ryan CJ, Smith MR, de Bono JS, et al; COU-AA-302 Investigators. Abiraterone in metastatic prostate cancer without previous chemotherapy. N Engl J Med. 2013;368(2):138-48.
-
(2013)
N Engl J Med
, vol.368
, Issue.2
, pp. 138-148
-
-
Ryan, C.J.1
Smith, M.R.2
De Bono, J.S.3
-
4
-
-
3042784503
-
Hormonal impact of the 17alpha-hydroxylase/C(17,20)-lyase inhibitor abiraterone acetate (CB7630) in patients with prostate cancer
-
O’Donnell A, Judson I, Dowsett M, et al. Hormonal impact of the 17alpha-hydroxylase/C(17,20)-lyase inhibitor abiraterone acetate (CB7630) in patients with prostate cancer. Br J Cancer. 2004;90(12):2317-25.
-
(2004)
Br J Cancer
, vol.90
, Issue.12
, pp. 2317-2325
-
-
O’Donnell, A.1
Judson, I.2
Dowsett, M.3
-
5
-
-
53749090666
-
Phase I clinical trial of a selective inhibitor of CYP17, abiraterone acetate, confirms that castration-resistant prostate cancer commonly remains hormone driven
-
Attard G, Reid AH, Yap TA, et al. Phase I clinical trial of a selective inhibitor of CYP17, abiraterone acetate, confirms that castration-resistant prostate cancer commonly remains hormone driven. J Clin Oncol. 2008;26(28):4563-71.
-
(2008)
J Clin Oncol
, vol.26
, Issue.28
, pp. 4563-4571
-
-
Attard, G.1
Reid, A.H.2
Yap, T.A.3
-
6
-
-
65649090203
-
Development of a second-generation antiandrogen for treatment of advanced prostate cancer
-
Tran C, Ouk S, Clegg NJ, et al. Development of a second-generation antiandrogen for treatment of advanced prostate cancer. Science. 2009;324(5928):787-90.
-
(2009)
Science
, vol.324
, Issue.5928
, pp. 787-790
-
-
Tran, C.1
Ouk, S.2
Clegg, N.J.3
-
7
-
-
77952105685
-
Antitumour activity of MDV3100 in castration-resistant prostate cancer: A phase 1-2 study
-
Scher HI, Beer TM, Higano CS, et al. Antitumour activity of MDV3100 in castration-resistant prostate cancer: a phase 1-2 study. Lancet. 2010;375(9724):1437-46.
-
(2010)
Lancet
, vol.375
, Issue.9724
, pp. 1437-1446
-
-
Scher, H.I.1
Beer, T.M.2
Higano, C.S.3
-
8
-
-
84866770294
-
AFFIRM Investigators. Increased survival with enzalutamide in prostate cancer after chemotherapy
-
Scher HI, Fizazi K, Saad F, et al; AFFIRM Investigators. Increased survival with enzalutamide in prostate cancer after chemotherapy. N Engl J Med. 2012;367(13):1187-97.
-
(2012)
N Engl J Med
, vol.367
, Issue.13
, pp. 1187-1197
-
-
Scher, H.I.1
Fizazi, K.2
Saad, F.3
-
9
-
-
79957443342
-
COU-AA-301 Investigators. Abiraterone and increased survival in metastatic prostate cancer
-
de Bono JS, Logothetis CJ, Molina A, et al; COU-AA-301 Investigators. Abiraterone and increased survival in metastatic prostate cancer. N Engl J Med. 2011;364(21):1995-2005.
-
(2011)
N Engl J Med
, vol.364
, Issue.21
, pp. 1995-2005
-
-
De Bono, J.S.1
Logothetis, C.J.2
Molina, A.3
-
10
-
-
84922121997
-
Understanding the mechanisms of androgen deprivation resistance in prostate cancer at the molecular level
-
Karantanos T, Evans CP, Tombal B, Thompson TC, Montironi R, Isaacs WB. Understanding the mechanisms of androgen deprivation resistance in prostate cancer at the molecular level. Eur Urol. 2015;67(3):470-9.
-
(2015)
Eur Urol
, vol.67
, Issue.3
, pp. 470-479
-
-
Karantanos, T.1
Evans, C.P.2
Tombal, B.3
Thompson, T.C.4
Montironi, R.5
Isaacs, W.B.6
-
11
-
-
84933557037
-
Androgen pathway resistance in prostate cancer and therapeutic implications
-
Maughan BL, Antonarakis ES. Androgen pathway resistance in prostate cancer and therapeutic implications. Expert Opin Pharmacother. 2015;16(10):1521-37.
-
(2015)
Expert Opin Pharmacother
, vol.16
, Issue.10
, pp. 1521-1537
-
-
Maughan, B.L.1
Antonarakis, E.S.2
-
12
-
-
0029011116
-
Mutation of the androgen-receptor gene in metastatic androgen-independent prostate cancer
-
Taplin ME, Bubley GJ, Shuster TD, et al. Mutation of the androgen-receptor gene in metastatic androgen-independent prostate cancer. N Engl J Med. 1995;332(21):1393-8.
-
(1995)
N Engl J Med
, vol.332
, Issue.21
, pp. 1393-1398
-
-
Taplin, M.E.1
Bubley, G.J.2
Shuster, T.D.3
-
13
-
-
80052827038
-
Resistance to CYP17A1 inhibition with abiraterone in castration-resistant prostate cancer: Induction of steroidogenesis and androgen receptor splice variants
-
Mostaghel EA, Marck BT, Plymate SR, et al. Resistance to CYP17A1 inhibition with abiraterone in castration-resistant prostate cancer: induction of steroidogenesis and androgen receptor splice variants. Clin Cancer Res. 2011;17(18):5913-25.
-
(2011)
Clin Cancer Res
, vol.17
, Issue.18
, pp. 5913-5925
-
-
Mostaghel, E.A.1
Marck, B.T.2
Plymate, S.R.3
-
14
-
-
84927671644
-
Generation 2.5 antisense oligonucleotides targeting the androgen receptor and its splice variants suppress enzalutamide-resistant prostate cancer cell growth
-
Yamamoto Y, Loriot Y, Beraldi E, et al. Generation 2.5 antisense oligonucleotides targeting the androgen receptor and its splice variants suppress enzalutamide-resistant prostate cancer cell growth. Clin Cancer Res. 2015;21(7):1675-87.
-
(2015)
Clin Cancer Res
, vol.21
, Issue.7
, pp. 1675-1687
-
-
Yamamoto, Y.1
Loriot, Y.2
Beraldi, E.3
-
15
-
-
84933510527
-
Androgen receptor gene aberrations in circulating cell-free DNA: Biomarkers of therapeutic resistance in castration-resistant prostate cancer
-
Azad AA, Volik SV, Wyatt AW, et al. Androgen receptor gene aberrations in circulating cell-free DNA: biomarkers of therapeutic resistance in castration-resistant prostate cancer. Clin Cancer Res. 2015;21(10):2315-24.
-
(2015)
Clin Cancer Res
, vol.21
, Issue.10
, pp. 2315-2324
-
-
Azad, A.A.1
Volik, S.V.2
Wyatt, A.W.3
-
16
-
-
84947245381
-
Plasma AR and abiraterone-resistant prostate cancer
-
312re10
-
Romanel A, Tandefelt DG, Conteduca V, et al. Plasma AR and abiraterone-resistant prostate cancer. Sci Transl Med. 2015;7(312):312re10.
-
(2015)
Sci Transl Med
, vol.7
, Issue.312
-
-
Romanel, A.1
Tandefelt, D.G.2
Conteduca, V.3
-
17
-
-
51049098138
-
Androgen levels increase by intratumoral de novo steroidogenesis during progression of castration-resistant prostate cancer
-
Locke JA, Guns ES, Lubik AA, et al. Androgen levels increase by intratumoral de novo steroidogenesis during progression of castration-resistant prostate cancer. Cancer Res. 2008;68(15):6407-15.
-
(2008)
Cancer Res
, vol.68
, Issue.15
, pp. 6407-6415
-
-
Locke, J.A.1
Guns, E.S.2
Lubik, A.A.3
-
18
-
-
84929292191
-
Circulating cell-free AR and CYP17A1 copy number variations may associate with outcome of metastatic castration-resistant prostate cancer patients treated with abiraterone
-
Salvi S, Casadio V, Conteduca V, et al. Circulating cell-free AR and CYP17A1 copy number variations may associate with outcome of metastatic castration-resistant prostate cancer patients treated with abiraterone. Br J Cancer. 2015;112(10):1717-24.
-
(2015)
Br J Cancer
, vol.112
, Issue.10
, pp. 1717-1724
-
-
Salvi, S.1
Casadio, V.2
Conteduca, V.3
-
19
-
-
78651492301
-
“Getting from here to there”-mechanisms and limitations to the activation of the androgen receptor in castration-resistant prostate cancer
-
Sharifi N, McPhaul MJ, Auchus RJ. “Getting from here to there”-mechanisms and limitations to the activation of the androgen receptor in castration-resistant prostate cancer. J Investig Med. 2010;58(8):938-44.
-
(2010)
J Investig Med
, vol.58
, Issue.8
, pp. 938-944
-
-
Sharifi, N.1
McPhaul, M.J.2
Auchus, R.J.3
-
20
-
-
48549089747
-
Splicing of a novel androgen receptor exon generates a constitutively active androgen receptor that mediates prostate cancer therapy resistance
-
Dehm SM, Schmidt LJ, Heemers HV, Vessella RL, Tindall DJ. Splicing of a novel androgen receptor exon generates a constitutively active androgen receptor that mediates prostate cancer therapy resistance. Cancer Res. 2008;68(13):5469-77.
-
(2008)
Cancer Res
, vol.68
, Issue.13
, pp. 5469-5477
-
-
Dehm, S.M.1
Schmidt, L.J.2
Heemers, H.V.3
Vessella, R.L.4
Tindall, D.J.5
-
21
-
-
84882274167
-
NF-kappaB2/p52 induces resistance to enzalutamide in prostate cancer: Role of androgen receptor and its variants
-
Nadiminty N, Tummala R, Liu C, et al. NF-kappaB2/p52 induces resistance to enzalutamide in prostate cancer: role of androgen receptor and its variants. Mol Cancer Ther. 2013;12(8):1629-37.
-
(2013)
Mol Cancer Ther
, vol.12
, Issue.8
, pp. 1629-1637
-
-
Nadiminty, N.1
Tummala, R.2
Liu, C.3
-
22
-
-
84901199317
-
Decoding the androgen receptor splice variants
-
Lu C, Luo J. Decoding the androgen receptor splice variants. Transl Androl Urol. 2013;2(3):178-86.
-
(2013)
Transl Androl Urol
, vol.2
, Issue.3
, pp. 178-186
-
-
Lu, C.1
Luo, J.2
-
23
-
-
84930225081
-
Integrative clinical genomics of advanced prostate cancer
-
Robinson D, Van Allen EM, Wu YM, et al. Integrative clinical genomics of advanced prostate cancer. Cell. 2015;161(5):1215-28.
-
(2015)
Cell
, vol.161
, Issue.5
, pp. 1215-1228
-
-
Robinson, D.1
Van Allen, E.M.2
Wu, Y.M.3
-
24
-
-
84869094406
-
AR intragenic deletions linked to androgen receptor splice variant expression and activity in models of prostate cancer progression
-
Li Y, Hwang TH, Oseth LA, et al. AR intragenic deletions linked to androgen receptor splice variant expression and activity in models of prostate cancer progression. Oncogene. 2012;31(45):4759-67.
-
(2012)
Oncogene
, vol.31
, Issue.45
, pp. 4759-4767
-
-
Li, Y.1
Hwang, T.H.2
Oseth, L.A.3
-
25
-
-
58249110391
-
Ligand-independent androgen receptor variants derived from splicing of cryptic exons signify hormone-refractory prostate cancer
-
Hu R, Dunn TA, Wei S, et al. Ligand-independent androgen receptor variants derived from splicing of cryptic exons signify hormone-refractory prostate cancer. Cancer Res. 2009;69(1):16-22.
-
(2009)
Cancer Res
, vol.69
, Issue.1
, pp. 16-22
-
-
Hu, R.1
Dunn, T.A.2
Wei, S.3
-
26
-
-
84863979005
-
Distinct transcriptional programs mediated by the ligand-dependent full-length androgen receptor and its splice variants in castration-resistant prostate cancer
-
Hu R, Lu C, Mostaghel EA, et al. Distinct transcriptional programs mediated by the ligand-dependent full-length androgen receptor and its splice variants in castration-resistant prostate cancer. Cancer Res. 2012;72(14):3457-62.
-
(2012)
Cancer Res
, vol.72
, Issue.14
, pp. 3457-3462
-
-
Hu, R.1
Lu, C.2
Mostaghel, E.A.3
-
27
-
-
84907057471
-
AR-V7 and resistance to enzalutamide and abiraterone in prostate cancer
-
Antonarakis ES, Lu C, Wang H, et al. AR-V7 and resistance to enzalutamide and abiraterone in prostate cancer. N Engl J Med. 2014;371(11):1028-38.
-
(2014)
N Engl J Med
, vol.371
, Issue.11
, pp. 1028-1038
-
-
Antonarakis, E.S.1
Lu, C.2
Wang, H.3
-
28
-
-
85068160367
-
Detecting predictive androgen receptor modifications in circulating prostate cancer cells
-
[Epub ahead of print]
-
Steinestel J, Luedeke M, Arndt A, et al. Detecting predictive androgen receptor modifications in circulating prostate cancer cells. Oncotarget. 2015. [Epub ahead of print]. Doi: 10.18632/oncotarget.3925
-
(2015)
Oncotarget
-
-
Steinestel, J.1
Luedeke, M.2
Arndt, A.3
-
29
-
-
84926160408
-
Molecular characterization of enzalutamide-treated bone metastatic castration-resistant prostate cancer
-
Efstathiou E, Titus M, Wen S, et al. Molecular characterization of enzalutamide-treated bone metastatic castration-resistant prostate cancer. Eur Urol. 2015;67(1):53-60.
-
(2015)
Eur Urol
, vol.67
, Issue.1
, pp. 53-60
-
-
Efstathiou, E.1
Titus, M.2
Wen, S.3
-
30
-
-
84861581164
-
Exome sequencing identifies recurrent SPOP, FOXA1 and MED12 mutations in prostate cancer
-
Barbieri CE, Baca SC, Lawrence MS, et al. Exome sequencing identifies recurrent SPOP, FOXA1 and MED12 mutations in prostate cancer. Nat Genet. 2012;44(6):685-9.
-
(2012)
Nat Genet
, vol.44
, Issue.6
, pp. 685-689
-
-
Barbieri, C.E.1
Baca, S.C.2
Lawrence, M.S.3
-
31
-
-
0042130389
-
Cancer and Leukemia Group B Study 9663. Androgen receptor mutations in androgen-independent prostate cancer: Cancer and leukemia group B study 9663
-
Taplin ME, Rajeshkumar B, Halabi S, et al; Cancer and Leukemia Group B Study 9663. Androgen receptor mutations in androgen-independent prostate cancer: cancer and leukemia group B study 9663. J Clin Oncol. 2003;21(14):2673-8.
-
(2003)
J Clin Oncol
, vol.21
, Issue.14
, pp. 2673-2678
-
-
Taplin, M.E.1
Rajeshkumar, B.2
Halabi, S.3
-
32
-
-
77954255681
-
Integrative genomic profiling of human prostate cancer
-
Taylor BS, Schultz N, Hieronymus H, et al. Integrative genomic profiling of human prostate cancer. Cancer Cell. 2010;18(1):11-22.
-
(2010)
Cancer Cell
, vol.18
, Issue.1
, pp. 11-22
-
-
Taylor, B.S.1
Schultz, N.2
Hieronymus, H.3
-
33
-
-
84863723010
-
The mutational landscape of lethal castration-resistant prostate cancer
-
Grasso CS, Wu YM, Robinson DR, et al. The mutational landscape of lethal castration-resistant prostate cancer. Nature. 2012;487(7406):239-43.
-
(2012)
Nature
, vol.487
, Issue.7406
, pp. 239-243
-
-
Grasso, C.S.1
Wu, Y.M.2
Robinson, D.R.3
-
34
-
-
84857713667
-
The impact of point mutations in the human androgen receptor: Classification of mutations on the basis of transcriptional activity
-
Hay CW, McEwan IJ. The impact of point mutations in the human androgen receptor: classification of mutations on the basis of transcriptional activity. PLoS One. 2012;7(3):e32514.
-
(2012)
Plos One
, vol.7
, Issue.3
, pp. e32514
-
-
Hay, C.W.1
McEwan, I.J.2
-
35
-
-
84864356765
-
The androgen receptor gene mutations database: 2012 update
-
Gottlieb B, Beitel LK, Nadarajah A, Paliouras M, Trifiro M. The androgen receptor gene mutations database: 2012 update. Hum Mutat. 2012;33(5):887-94.
-
(2012)
Hum Mutat
, vol.33
, Issue.5
, pp. 887-894
-
-
Gottlieb, B.1
Beitel, L.K.2
Nadarajah, A.3
Paliouras, M.4
Trifiro, M.5
-
36
-
-
0033152164
-
Selection for androgen receptor mutations in prostate cancers treated with androgen antagonist
-
Taplin ME, Bubley GJ, Ko YJ, et al. Selection for androgen receptor mutations in prostate cancers treated with androgen antagonist. Cancer Res. 1999;59(11):2511-5.
-
(1999)
Cancer Res
, vol.59
, Issue.11
, pp. 2511-2515
-
-
Taplin, M.E.1
Bubley, G.J.2
Ko, Y.J.3
-
37
-
-
0037143096
-
Broadened ligand responsiveness of androgen receptor mutants obtained by random amino acid substitution of H874 and mutation hot spot T877 in prostate cancer
-
Steketee K, Timmerman L, Ziel-VanderMade AC, Doesburg P, Brinkmann AO, Trapman J. Broadened ligand responsiveness of androgen receptor mutants obtained by random amino acid substitution of H874 and mutation hot spot T877 in prostate cancer. Int J Cancer. 2002;100(3):309-17.
-
(2002)
Int J Cancer
, vol.100
, Issue.3
, pp. 309-317
-
-
Steketee, K.1
Timmerman, L.2
Ziel-Vandermade, A.C.3
Doesburg, P.4
Brinkmann, A.O.5
Trapman, J.6
-
38
-
-
85003173512
-
Mutant androgen receptor detected in an advanced-stage prostatic carcinoma is activated by adrenal androgens and progesterone
-
Culig Z, Hobisch A, Cronauer MV, et al. Mutant androgen receptor detected in an advanced-stage prostatic carcinoma is activated by adrenal androgens and progesterone. Mol Endocrinol. 1993;7(12):1541-50.
-
(1993)
Mol Endocrinol
, vol.7
, Issue.12
, pp. 1541-1550
-
-
Culig, Z.1
Hobisch, A.2
Cronauer, M.V.3
-
39
-
-
0032883932
-
Switch from antagonist to agonist of the androgen receptor bicalutamide is associated with prostate tumour progression in a new model system
-
Culig Z, Hoffmann J, Erdel M, et al. Switch from antagonist to agonist of the androgen receptor bicalutamide is associated with prostate tumour progression in a new model system. Br J Cancer. 1999;81(2):242-51.
-
(1999)
Br J Cancer
, vol.81
, Issue.2
, pp. 242-251
-
-
Culig, Z.1
Hoffmann, J.2
Erdel, M.3
-
40
-
-
84927655173
-
Abiraterone treatment in castration-resistant prostate cancer selects for progesterone responsive mutant androgen receptors
-
Chen EJ, Sowalsky AG, Gao S, et al. Abiraterone treatment in castration-resistant prostate cancer selects for progesterone responsive mutant androgen receptors. Clin Cancer Res. 2015;21(6):1273-80.
-
(2015)
Clin Cancer Res
, vol.21
, Issue.6
, pp. 1273-1280
-
-
Chen, E.J.1
Sowalsky, A.G.2
Gao, S.3
-
41
-
-
0031986409
-
High dose bicalutamide for androgen independent prostate cancer: Effect of prior hormonal therapy
-
Joyce R, Fenton MA, Rode P, et al. High dose bicalutamide for androgen independent prostate cancer: effect of prior hormonal therapy. J Urol. 1998;159(1):149-53.
-
(1998)
J Urol
, vol.159
, Issue.1
, pp. 149-153
-
-
Joyce, R.1
Fenton, M.A.2
Rode, P.3
-
42
-
-
84879067087
-
Overcoming mutation-based resistance to antiandrogens with rational drug design
-
Balbas MD, Evans MJ, Hosfield DJ, et al. Overcoming mutation-based resistance to antiandrogens with rational drug design. Elife. 2013;2:e00499.
-
(2013)
Elife
, vol.2
-
-
Balbas, M.D.1
Evans, M.J.2
Hosfield, D.J.3
-
43
-
-
84885214146
-
An F876 L mutation in androgen receptor confers genetic and phenotypic resistance to MDV3100 (Enzalutamide)
-
Korpal M, Korn JM, Gao X, et al. An F876 L mutation in androgen receptor confers genetic and phenotypic resistance to MDV3100 (enzalutamide). Cancer Discov. 2013;3(9):1030-43.
-
(2013)
Cancer Discov
, vol.3
, Issue.9
, pp. 1030-1043
-
-
Korpal, M.1
Korn, J.M.2
Gao, X.3
-
44
-
-
84885210324
-
A clinically relevant androgen receptor mutation confers resistance to second-generation antiandrogens enzalutamide and ARN-509
-
Joseph JD, Lu N, Qian J, et al. A clinically relevant androgen receptor mutation confers resistance to second-generation antiandrogens enzalutamide and ARN-509. Cancer Discov. 2013;3(9):1020-9.
-
(2013)
Cancer Discov
, vol.3
, Issue.9
, pp. 1020-1029
-
-
Joseph, J.D.1
Lu, N.2
Qian, J.3
-
45
-
-
84890078624
-
Glucocorticoid receptor confers resistance to antiandrogens by bypassing androgen receptor blockade
-
Arora VK, Schenkein E, Murali R, et al. Glucocorticoid receptor confers resistance to antiandrogens by bypassing androgen receptor blockade. Cell. 2013;155(6):1309-22.
-
(2013)
Cell
, vol.155
, Issue.6
, pp. 1309-1322
-
-
Arora, V.K.1
Schenkein, E.2
Murali, R.3
-
46
-
-
84860523917
-
Interactions of abiraterone, eplerenone, and prednisolone with wild-type and mutant androgen receptor: A rationale for increasing abiraterone exposure or combining with MDV3100
-
Richards J, Lim AC, Hay CW, et al. Interactions of abiraterone, eplerenone, and prednisolone with wild-type and mutant androgen receptor: a rationale for increasing abiraterone exposure or combining with MDV3100. Cancer Res. 2012;72(9):2176-82.
-
(2012)
Cancer Res
, vol.72
, Issue.9
, pp. 2176-2182
-
-
Richards, J.1
Lim, A.C.2
Hay, C.W.3
-
47
-
-
84907285681
-
Tumor clone dynamics in lethal prostate cancer
-
254ra125
-
Carreira S, Romanel A, Goodall J, et al. Tumor clone dynamics in lethal prostate cancer. Sci Transl Med. 2014;6(254):254ra125.
-
(2014)
Sci Transl Med
, vol.6
, Issue.254
-
-
Carreira, S.1
Romanel, A.2
Goodall, J.3
-
48
-
-
84874918445
-
FoxA1 specifies unique androgen and glucocorticoid receptor binding events in prostate cancer cells
-
Sahu B, Laakso M, Pihlajamaa P, et al. FoxA1 specifies unique androgen and glucocorticoid receptor binding events in prostate cancer cells. Cancer Res. 2013;73(5):1570-80.
-
(2013)
Cancer Res
, vol.73
, Issue.5
, pp. 1570-1580
-
-
Sahu, B.1
Laakso, M.2
Pihlajamaa, P.3
-
49
-
-
0025110831
-
Association of glucocorticoid receptors with prostate nuclear sites for androgen receptors and with androgen response elements
-
Davies P, Rushmere NK. Association of glucocorticoid receptors with prostate nuclear sites for androgen receptors and with androgen response elements. J Mol Endocrinol. 1990;5(2):117-27.
-
(1990)
J Mol Endocrinol
, vol.5
, Issue.2
, pp. 117-127
-
-
Davies, P.1
Rushmere, N.K.2
-
50
-
-
0037064106
-
Ligand-independent activation of the androgen receptor by interleukin-6 and the role of steroid receptor coactivator-1 in prostate cancer cells
-
Ueda T, Mawji NR, Bruchovsky N, Sadar MD. Ligand-independent activation of the androgen receptor by interleukin-6 and the role of steroid receptor coactivator-1 in prostate cancer cells. J Biol Chem. 2002;277(41):38087-94.
-
(2002)
J Biol Chem
, vol.277
, Issue.41
, pp. 38087-38094
-
-
Ueda, T.1
Mawji, N.R.2
Bruchovsky, N.3
Sadar, M.D.4
-
51
-
-
66449085018
-
Interleukin-6 increases prostate cancer cells resistance to bicalutamide via TIF2
-
Feng S, Tang Q, Sun M, Chun JY, Evans CP, Gao AC. Interleukin-6 increases prostate cancer cells resistance to bicalutamide via TIF2. Mol Cancer Ther. 2009;8(3):665-71.
-
(2009)
Mol Cancer Ther
, vol.8
, Issue.3
, pp. 665-671
-
-
Feng, S.1
Tang, Q.2
Sun, M.3
Chun, J.Y.4
Evans, C.P.5
Gao, A.C.6
-
52
-
-
0028113415
-
Androgen receptor activation in prostatic tumor cell lines by insulin-like growth factor-I, keratinocyte growth factor, and epidermal growth factor
-
Culig Z, Hobisch A, Cronauer MV, et al. Androgen receptor activation in prostatic tumor cell lines by insulin-like growth factor-I, keratinocyte growth factor, and epidermal growth factor. Cancer Res. 1994;54(20):5474-8.
-
(1994)
Cancer Res
, vol.54
, Issue.20
, pp. 5474-5478
-
-
Culig, Z.1
Hobisch, A.2
Cronauer, M.V.3
-
53
-
-
7944234374
-
HER2/neu kinase-dependent modulation of androgen receptor function through effects on DNA binding and stability
-
Mellinghoff IK, Vivanco I, Kwon A, Tran C, Wongvipat J, Sawyers CL. HER2/neu kinase-dependent modulation of androgen receptor function through effects on DNA binding and stability. Cancer Cell. 2004;6(5):517-27.
-
(2004)
Cancer Cell
, vol.6
, Issue.5
, pp. 517-527
-
-
Mellinghoff, I.K.1
Vivanco, I.2
Kwon, A.3
Tran, C.4
Wongvipat, J.5
Sawyers, C.L.6
-
54
-
-
80053506738
-
Dual EGFR/HER2 inhibition sensitizes prostate cancer cells to androgen withdrawal by suppressing ErbB3
-
Chen L, Mooso BA, Jathal MK, et al. Dual EGFR/HER2 inhibition sensitizes prostate cancer cells to androgen withdrawal by suppressing ErbB3. Clin Cancer Res. 2011;17(19):6218-28.
-
(2011)
Clin Cancer Res
, vol.17
, Issue.19
, pp. 6218-6228
-
-
Chen, L.1
Mooso, B.A.2
Jathal, M.K.3
-
55
-
-
79955975429
-
Reciprocal feedback regulation of PI3K and androgen receptor signaling in PTEN-deficient prostate cancer
-
Carver BS, Chapinski C, Wongvipat J, et al. Reciprocal feedback regulation of PI3K and androgen receptor signaling in PTEN-deficient prostate cancer. Cancer Cell. 2011;19(5):575-86.
-
(2011)
Cancer Cell
, vol.19
, Issue.5
, pp. 575-586
-
-
Carver, B.S.1
Chapinski, C.2
Wongvipat, J.3
-
56
-
-
70349731660
-
Inhibition of tumor growth progression by antiandrogens and mTOR inhibitor in a pten-deficient mouse model of prostate cancer
-
Zhang W, Zhu J, Efferson CL, et al. Inhibition of tumor growth progression by antiandrogens and mTOR inhibitor in a pten-deficient mouse model of prostate cancer. Cancer Res. 2009;69(18):7466-72.
-
(2009)
Cancer Res
, vol.69
, Issue.18
, pp. 7466-7472
-
-
Zhang, W.1
Zhu, J.2
Efferson, C.L.3
-
57
-
-
51349111250
-
Targeting AKT/mTOR and ERK MAPK signaling inhibits hormone-refractory prostate cancer in a preclinical mouse model
-
Kinkade CW, Castillo-Martin M, Puzio-Kuter A, et al. Targeting AKT/mTOR and ERK MAPK signaling inhibits hormone-refractory prostate cancer in a preclinical mouse model. J Clin Invest. 2008;118(9):3051-64.
-
(2008)
J Clin Invest
, vol.118
, Issue.9
, pp. 3051-3064
-
-
Kinkade, C.W.1
Castillo-Martin, M.2
Puzio-Kuter, A.3
-
58
-
-
84896518278
-
P300 acetyltransferase regulates androgen receptor degradation and PTEN-deficient prostate tumorigenesis
-
Zhong J, Ding L, Bohrer LR, et al. p300 acetyltransferase regulates androgen receptor degradation and PTEN-deficient prostate tumorigenesis. Cancer Res. 2014;74(6):1870-80.
-
(2014)
Cancer Res
, vol.74
, Issue.6
, pp. 1870-1880
-
-
Zhong, J.1
Ding, L.2
Bohrer, L.R.3
-
59
-
-
0037108955
-
P300 mediates androgen-independent transactivation of the androgen receptor by interleukin 6
-
Debes JD, Schmidt LJ, Huang H, Tindall DJ. P300 mediates androgen-independent transactivation of the androgen receptor by interleukin 6. Cancer Res. 2002;62(20):5632-6.
-
(2002)
Cancer Res
, vol.62
, Issue.20
, pp. 5632-5636
-
-
Debes, J.D.1
Schmidt, L.J.2
Huang, H.3
Tindall, D.J.4
-
60
-
-
44849135184
-
Stat3 promotes metastatic progression of prostate cancer
-
Abdulghani J, Gu L, Dagvadorj A, et al. Stat3 promotes metastatic progression of prostate cancer. Am J Pathol. 2008;172(6):1717-28.
-
(2008)
Am J Pathol
, vol.172
, Issue.6
, pp. 1717-1728
-
-
Abdulghani, J.1
Gu, L.2
Dagvadorj, A.3
-
61
-
-
84894284619
-
Loss of androgen receptor expression promotes a stem-like cell phenotype in prostate cancer through STAT3 signaling
-
Schroeder A, Herrmann A, Cherryholmes G, et al. Loss of androgen receptor expression promotes a stem-like cell phenotype in prostate cancer through STAT3 signaling. Cancer Res. 2014;74(4):1227-37.
-
(2014)
Cancer Res
, vol.74
, Issue.4
, pp. 1227-1237
-
-
Schroeder, A.1
Herrmann, A.2
Cherryholmes, G.3
-
62
-
-
84891160894
-
Inhibition of constitutively active Stat3 reverses enzalutamide resistance in LNCaP derivative prostate cancer cells
-
Liu C, Zhu Y, Lou W, Cui Y, Evans CP, Gao AC. Inhibition of constitutively active Stat3 reverses enzalutamide resistance in LNCaP derivative prostate cancer cells. Prostate. 2014;74(2):201-9.
-
(2014)
Prostate
, vol.74
, Issue.2
, pp. 201-209
-
-
Liu, C.1
Zhu, Y.2
Lou, W.3
Cui, Y.4
Evans, C.P.5
Gao, A.C.6
-
63
-
-
0042978480
-
Androgen receptor gene amplification and protein expression in hormone refractory prostate cancer
-
Edwards J, Krishna NS, Grigor KM, Bartlett JM. Androgen receptor gene amplification and protein expression in hormone refractory prostate cancer. Br J Cancer. 2003;89(3):552-6.
-
(2003)
Br J Cancer
, vol.89
, Issue.3
, pp. 552-556
-
-
Edwards, J.1
Krishna, N.S.2
Grigor, K.M.3
Bartlett, J.M.4
-
64
-
-
77956849003
-
New tricks from an old oncogene: Gene fusion and copy number alterations of MYB in human cancer
-
Stenman G, Andersson MK, Andren Y. New tricks from an old oncogene: gene fusion and copy number alterations of MYB in human cancer. Cell Cycle. 2010;9(15):2986-95.
-
(2010)
Cell Cycle
, vol.9
, Issue.15
, pp. 2986-2995
-
-
Stenman, G.1
Ersson, M.K.2
Ren, Y.3
-
65
-
-
84901244617
-
Targeting poly(ADP-ribose) polymerase and the c-myb-regulated DNA damage response pathway in castration-resistant prostate cancer
-
ra47
-
Li L, Chang W, Yang G, et al. Targeting poly(ADP-ribose) polymerase and the c-myb-regulated DNA damage response pathway in castration-resistant prostate cancer. Sci Signal. 2014;7(326):ra47.
-
(2014)
Sci Signal
, vol.7
, Issue.326
-
-
Li, L.1
Chang, W.2
Yang, G.3
-
66
-
-
84866683064
-
Understanding the lethal variant of prostate cancer: Power of examining extremes
-
Aparicio A, Logothetis CJ, Maity SN. Understanding the lethal variant of prostate cancer: power of examining extremes. Cancer Discov. 2011;1(6):466-8.
-
(2011)
Cancer Discov
, vol.1
, Issue.6
, pp. 466-468
-
-
Aparicio, A.1
Logothetis, C.J.2
Maity, S.N.3
-
67
-
-
84873048485
-
Concurrent AURKA and MYCN gene amplifications are harbingers of lethal treatment-related neuroendocrine prostate cancer
-
Mosquera JM, Beltran H, Park K, et al. Concurrent AURKA and MYCN gene amplifications are harbingers of lethal treatment-related neuroendocrine prostate cancer. Neoplasia. 2013;15(1):1-10.
-
(2013)
Neoplasia
, vol.15
, Issue.1
, pp. 1-10
-
-
Mosquera, J.M.1
Beltran, H.2
Park, K.3
-
68
-
-
84860168795
-
Molecular characterization of neuroendocrine prostate cancer and identification of new drug targets
-
Beltran H, Rickman DS, Park K, et al. Molecular characterization of neuroendocrine prostate cancer and identification of new drug targets. Cancer Discov. 2011;1(6):487-95.
-
(2011)
Cancer Discov
, vol.1
, Issue.6
, pp. 487-495
-
-
Beltran, H.1
Rickman, D.S.2
Park, K.3
-
69
-
-
84893296911
-
REST mediates androgen receptor actions on gene repression and predicts early recurrence of prostate cancer
-
Svensson C, Ceder J, Iglesias-Gato D, et al. REST mediates androgen receptor actions on gene repression and predicts early recurrence of prostate cancer. Nucleic Acids Res. 2014;42(2):999-1015.
-
(2014)
Nucleic Acids Res
, vol.42
, Issue.2
, pp. 999-1015
-
-
Svensson, C.1
Ceder, J.2
Iglesias-Gato, D.3
-
70
-
-
84896715260
-
Rb loss is characteristic of prostatic small cell neuroendocrine carcinoma
-
Tan HL, Sood A, Rahimi HA, et al. Rb loss is characteristic of prostatic small cell neuroendocrine carcinoma. Clin Cancer Res. 2014;20(4):890-903.
-
(2014)
Clin Cancer Res
, vol.20
, Issue.4
, pp. 890-903
-
-
Tan, H.L.1
Sood, A.2
Rahimi, H.A.3
-
71
-
-
84962304309
-
Combined tumor suppressor defects characterize clinically defined aggressive variant prostate cancers
-
[Epub ahead of print]
-
Aparicio AM, Shen L, Li Ning Tapia EM, et al. Combined tumor suppressor defects characterize clinically defined aggressive variant prostate cancers. Clin Cancer Res. 2015. [Epub ahead of print]. Doi: 10.1158/1078-0432.CCR-15-1259
-
(2015)
Clin Cancer Res
-
-
Aparicio, A.M.1
Shen, L.2
Li Ning Tapia, E.M.3
-
72
-
-
84962609323
-
Androgen receptor (AR) amplification in patients (pts) with metastatic castration resistant prostate cancer (mCRPC) resistant to abiraterone (abi) and enzalutamide (enz): Preliminary results from the SU2C/PCF/AACR West Coast Prostate Cancer Dream Team (WCDT)
-
abstr5068
-
Aggarwal RR, Thomas G, Youngren J, et al. Androgen receptor (AR) amplification in patients (pts) with metastatic castration resistant prostate cancer (mCRPC) resistant to abiraterone (abi) and enzalutamide (enz): Preliminary results from the SU2C/PCF/AACR West Coast Prostate Cancer Dream Team (WCDT). J Clin Oncol. 2015;33(suppl):abstr5068.
-
(2015)
J Clin Oncol
, vol.33
-
-
Aggarwal, R.R.1
Thomas, G.2
Youngren, J.3
-
73
-
-
84921371152
-
PD-L1 is highly expressed in enzalutamide resistant prostate cancer
-
Bishop JL, Sio A, Angeles A, et al. PD-L1 is highly expressed in enzalutamide resistant prostate cancer. Oncotarget. 2015;6(1):234-42.
-
(2015)
Oncotarget
, vol.6
, Issue.1
, pp. 234-242
-
-
Bishop, J.L.1
Sio, A.2
Angeles, A.3
-
74
-
-
84878632550
-
What are the molecules involved in regulatory T-cells induction by dendritic cells in cancer?
-
Ramos RN, de Moraes CJ, Zelante B, Barbuto JA. What are the molecules involved in regulatory T-cells induction by dendritic cells in cancer? Clin Dev Immunol. 2013;2013:806025.
-
(2013)
Clin Dev Immunol
, vol.2013
, pp. 806025
-
-
Ramos, R.N.1
De Moraes, C.J.2
Zelante, B.3
Barbuto, J.A.4
-
75
-
-
84947213601
-
Liquid biopsy: Clues on prostate cancer drug resistance
-
312fs45
-
Schweizer MT, Antonarakis ES. Liquid biopsy: clues on prostate cancer drug resistance. Sci Transl Med. 2015;7(312):312fs45.
-
(2015)
Sci Transl Med
, vol.7
, Issue.312
-
-
Schweizer, M.T.1
Antonarakis, E.S.2
|