메뉴 건너뛰기




Volumn 20, Issue 4, 2014, Pages 890-903

Rb loss is characteristic of prostatic small cell neuroendocrine carcinoma

Author keywords

[No Author keywords available]

Indexed keywords

PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; PROTEIN P53; RETINOBLASTOMA BINDING PROTEIN 1;

EID: 84896715260     PISSN: 10780432     EISSN: 15573265     Source Type: Journal    
DOI: 10.1158/1078-0432.CCR-13-1982     Document Type: Article
Times cited : (269)

References (56)
  • 2
    • 33846479832 scopus 로고    scopus 로고
    • Unusual and underappreciated: Small cell carcinoma of the prostate
    • Palmgren JS, Karavadia SS, Wakefield MR. Unusual and underappreciated: small cell carcinoma of the prostate. Semin Oncol 2007;34:22-9.
    • (2007) Semin Oncol , vol.34 , pp. 22-29
    • Palmgren, J.S.1    Karavadia, S.S.2    Wakefield, M.R.3
  • 3
    • 0034065893 scopus 로고    scopus 로고
    • Neuroendocrine expression in metastatic prostate cancer: Evaluation of high throughput tissue microarrays to detect heterogeneous protein expression
    • Mucci NR, Akdas G, Manely S, Rubin MA. Neuroendocrine expression in metastatic prostate cancer: evaluation of high throughput tissue microarrays to detect heterogeneous protein expression. Hum Pathol 2000;31:406-14.
    • (2000) Hum Pathol , vol.31 , pp. 406-414
    • Mucci, N.R.1    Akdas, G.2    Manely, S.3    Rubin, M.A.4
  • 5
    • 10844235652 scopus 로고    scopus 로고
    • Androgen-independent prostate cancer is a heterogeneous group of diseases: Lessons from a rapid autopsy program
    • Shah RB, Mehra R, Chinnaiyan AM, Shen R, Ghosh D, Zhou M, et al. Androgen-independent prostate cancer is a heterogeneous group of diseases: lessons from a rapid autopsy program. Cancer Res 2004;64: 9209-16.
    • (2004) Cancer Res , vol.64 , pp. 9209-9216
    • Shah, R.B.1    Mehra, R.2    Chinnaiyan, A.M.3    Shen, R.4    Ghosh, D.5    Zhou, M.6
  • 6
    • 0022330480 scopus 로고
    • Small-cell carcinoma of prostate. Transient complete remission with chemotherapy
    • Hindson DA, Knight LL, Ocker JM. Small-cell carcinoma of prostate. transient complete remission with chemotherapy. Urology 1985;26: 182-4.
    • (1985) Urology , vol.26 , pp. 182-184
    • Hindson, D.A.1    Knight, L.L.2    Ocker, J.M.3
  • 8
    • 0026628717 scopus 로고
    • Small cell carcinoma of prostate: Effectiveness of hormonal versus chemotherapy
    • Moore SR, Reinberg Y, Zhang G. Small cell carcinoma of prostate: effectiveness of hormonal versus chemotherapy. Urology 1992;39: 411-6.
    • (1992) Urology , vol.39 , pp. 411-416
    • Moore, S.R.1    Reinberg, Y.2    Zhang, G.3
  • 9
    • 0030811134 scopus 로고    scopus 로고
    • Small cell anaplastic carcinoma of the prostate: Seven new cases, review of the literature, and discussion of a therapeutic strategy
    • Rubenstein JH, Katin MJ, Mangano MM, Dauphin J, Salenius SA, Dosoretz DE, et al. Small cell anaplastic carcinoma of the prostate: seven new cases, review of the literature, and discussion of a therapeutic strategy. Am J Clin Oncol 1997;20:376-80.
    • (1997) Am J Clin Oncol , vol.20 , pp. 376-380
    • Rubenstein, J.H.1    Katin, M.J.2    Mangano, M.M.3    Dauphin, J.4    Salenius, S.A.5    Dosoretz, D.E.6
  • 10
    • 0037099524 scopus 로고    scopus 로고
    • Results of a phase II study with doxorubicin, etoposide, and cisplatin in patients with fully characterized small-cell carcinoma of the prostate
    • Papandreou CN, Daliani DD, Thall PF, Tu SM, Wang X, Reyes A, et al. Results of a phase II study with doxorubicin, etoposide, and cisplatin in patients with fully characterized small-cell carcinoma of the prostate. J Clin Oncol 2002;20:3072-80.
    • (2002) J Clin Oncol , vol.20 , pp. 3072-3080
    • Papandreou, C.N.1    Daliani, D.D.2    Thall, P.F.3    Tu, S.M.4    Wang, X.5    Reyes, A.6
  • 11
    • 35048868879 scopus 로고    scopus 로고
    • Treatment outcomes of small cell carcinoma of the prostate: A single-center study
    • Spiess PE, Pettaway CA, Vakar-Lopez F, Kassouf W, Wang X, Busby JE, et al. Treatment outcomes of small cell carcinoma of the prostate: a single-center study. Cancer 2007;110:1729-37.
    • (2007) Cancer , vol.110 , pp. 1729-1737
    • Spiess, P.E.1    Pettaway, C.A.2    Vakar-Lopez, F.3    Kassouf, W.4    Wang, X.5    Busby, J.E.6
  • 13
    • 84873048485 scopus 로고    scopus 로고
    • Concurrent AURKA and MYCN gene amplifications are harbingers of lethal treatment-related neuroendocrine prostate cancer
    • Mosquera JM, Beltran H, Park K, MacDonald TY, Robinson BD, Tagawa ST, et al. Concurrent AURKA and MYCN gene amplifications are harbingers of lethal treatment-related neuroendocrine prostate cancer. Neoplasia 2013;15:1-10.
    • (2013) Neoplasia , vol.15 , pp. 1-10
    • Mosquera, J.M.1    Beltran, H.2    Park, K.3    Macdonald, T.Y.4    Robinson, B.D.5    Tagawa, S.T.6
  • 14
    • 79961031503 scopus 로고    scopus 로고
    • ERG-TMPRSS2 rearrangement is shared by concurrent prostatic adenocarcinoma and prostatic small cell carcinoma and absent in small cell carcinoma of the urinary bladder: Evidence supporting monoclonal origin
    • Williamson SR, Zhang S, Yao JL, Huang J, Lopez-Beltran A, Shen S, et al. ERG-TMPRSS2 rearrangement is shared by concurrent prostatic adenocarcinoma and prostatic small cell carcinoma and absent in small cell carcinoma of the urinary bladder: evidence supporting monoclonal origin. Mod Pathol 2011;24:1120-7.
    • (2011) Mod Pathol , vol.24 , pp. 1120-1127
    • Williamson, S.R.1    Zhang, S.2    Yao, J.L.3    Huang, J.4    Lopez-Beltran, A.5    Shen, S.6
  • 16
    • 84860168795 scopus 로고    scopus 로고
    • Molecular characterization of neuroendocrine prostate cancer and identification of new drug targets
    • Beltran H, Rickman DS, Park K, Chae SS, Sboner A, MacDonald TY, et al. Molecular characterization of neuroendocrine prostate cancer and identification of new drug targets. Cancer Discov 2011;1: 487-95.
    • (2011) Cancer Discov , vol.1 , pp. 487-495
    • Beltran, H.1    Rickman, D.S.2    Park, K.3    Chae, S.S.4    Sboner, A.5    Macdonald, T.Y.6
  • 17
    • 65549118291 scopus 로고    scopus 로고
    • Shared TP53 gene mutation in morphologically and phenotypically distinct concurrent primary small cell neuroendocrine carcinoma and adenocarcinoma of the prostate
    • Hansel DE, Nakayama M, Luo J, Abukhdeir AM, Park BH, Bieberich CJ, et al. Shared TP53 gene mutation in morphologically and phenotypically distinct concurrent primary small cell neuroendocrine carcinoma and adenocarcinoma of the prostate. Prostate 2009;69:603-9.
    • (2009) Prostate , vol.69 , pp. 603-609
    • Hansel, D.E.1    Nakayama, M.2    Luo, J.3    Abukhdeir, A.M.4    Park, B.H.5    Bieberich, C.J.6
  • 18
    • 37549037864 scopus 로고    scopus 로고
    • Small cell carcinoma of the prostate. A morphologic and immunohistochemical study of 95 cases
    • Wang W, Epstein JI. Small cell carcinoma of the prostate. A morphologic and immunohistochemical study of 95 cases. Am J Surg Pathol 2008;32:65-71.
    • (2008) Am J Surg Pathol , vol.32 , pp. 65-71
    • Wang, W.1    Epstein, J.I.2
  • 20
    • 84866851740 scopus 로고    scopus 로고
    • Integrative genome analyses identify key somatic driver mutations of small-cell lung cancer
    • Peifer M, Fernandez-Cuesta L, Sos ML, George J, Seidel D, Kasper LH, et al. Integrative genome analyses identify key somatic driver mutations of small-cell lung cancer. Nat Genet 2012;44:1104-10.
    • (2012) Nat Genet , vol.44 , pp. 1104-1110
    • Peifer, M.1    Fernandez-Cuesta, L.2    Sos, M.L.3    George, J.4    Seidel, D.5    Kasper, L.H.6
  • 21
    • 0141523025 scopus 로고    scopus 로고
    • Induction of small cell lung cancer by somatic inactivation of both Trp53 and Rb1 in a conditional mouse model
    • Meuwissen R, Linn SC, Linnoila RI, Zevenhoven J, Mooi WJ, Berns A. Induction of small cell lung cancer by somatic inactivation of both Trp53 and Rb1 in a conditional mouse model. Cancer Cell 2003;4: 181-9.
    • (2003) Cancer Cell , vol.4 , pp. 181-189
    • Meuwissen, R.1    Linn, S.C.2    Linnoila, R.I.3    Zevenhoven, J.4    Mooi, W.J.5    Berns, A.6
  • 23
    • 33748078111 scopus 로고    scopus 로고
    • Synergy of p53 and rb deficiency in a conditional mouse model for metastatic prostate cancer
    • Zhou Z, Flesken-Nikitin A, Corney DC, Wang W, Goodrich DW, Roy-Burman P, et al. Synergy of p53 and rb deficiency in a conditional mouse model for metastatic prostate cancer. Cancer Res 2006;66: 7889-98.
    • (2006) Cancer Res , vol.66 , pp. 7889-7898
    • Zhou, Z.1    Flesken-Nikitin, A.2    Corney, D.C.3    Wang, W.4    Goodrich, D.W.5    Roy-Burman, P.6
  • 26
    • 84876064523 scopus 로고    scopus 로고
    • Targeted next-generation sequencing of advanced prostate cancer identifies potential therapeutic targets and disease heterogeneity
    • Beltran H, Yelensky R, Frampton GM,Park K, Downing SR, MacDonald TY, et al. Targeted next-generation sequencing of advanced prostate cancer identifies potential therapeutic targets and disease heterogeneity. Eur Urol 2013;63:920-6.
    • (2013) Eur Urol , vol.63 , pp. 920-926
    • Beltran, H.1    Yelensky, R.2    Frampton, G.M.3    Park, K.4    Downing, S.R.5    Macdonald, T.Y.6
  • 27
    • 84870659824 scopus 로고    scopus 로고
    • An immunohistochemical signature comprising PTEN, MYC, and Ki67 predicts progression in prostate cancer patients receiving adjuvant docetaxel after prostatectomy
    • Antonarakis ES, Keizman D, Zhang Z, Gurel B, Lotan TL, Hicks JL, et al. An immunohistochemical signature comprising PTEN, MYC, and Ki67 predicts progression in prostate cancer patients receiving adjuvant docetaxel after prostatectomy. Cancer 2012;118:6063-71.
    • (2012) Cancer , vol.118 , pp. 6063-6071
    • Antonarakis, E.S.1    Keizman, D.2    Zhang, Z.3    Gurel, B.4    Lotan, T.L.5    Hicks, J.L.6
  • 29
    • 34447311967 scopus 로고    scopus 로고
    • Immunohistochemical antibody cocktail staining (p63/HMWCK/AMACR) of ductal adenocarcinoma and Gleason pattern 4 cribriform and noncribriform acinar adenocarcinomas of the prostate
    • Herawi M, Epstein JI. Immunohistochemical antibody cocktail staining (p63/HMWCK/AMACR) of ductal adenocarcinoma and Gleason pattern 4 cribriform and noncribriform acinar adenocarcinomas of the prostate. Am J Surg Pathol 2007;31:889-94.
    • (2007) Am J Surg Pathol , vol.31 , pp. 889-894
    • Herawi, M.1    Epstein, J.I.2
  • 30
    • 67349257845 scopus 로고    scopus 로고
    • Copy number analysis indicates monoclonal origin of lethal metastatic prostate cancer
    • Liu W, Laitinen S, Khan S, Vihinen M, Kowalski J, Yu G, et al. Copy number analysis indicates monoclonal origin of lethal metastatic prostate cancer. Nat Med 2009;15:559-65.
    • (2009) Nat Med , vol.15 , pp. 559-565
    • Liu, W.1    Laitinen, S.2    Khan, S.3    Vihinen, M.4    Kowalski, J.5    Yu, G.6
  • 31
    • 80054111295 scopus 로고    scopus 로고
    • PTEN protein loss by immunostaining: Analytic validation and prognostic indicator for a high risk surgical cohort of prostate cancer patients
    • Lotan TL, Gurel B, Sutcliffe S, Esopi D, Liu W, Xu J, et al. PTEN protein loss by immunostaining: analytic validation and prognostic indicator for a high risk surgical cohort of prostate cancer patients. Clin Cancer Res 2011;17:6563-73.
    • (2011) Clin Cancer Res , vol.17 , pp. 6563-6573
    • Lotan, T.L.1    Gurel, B.2    Sutcliffe, S.3    Esopi, D.4    Liu, W.5    Xu, J.6
  • 34
    • 0034711299 scopus 로고    scopus 로고
    • Mullerian inhibiting substance inhibits ovarian cell growth through an rb-independent mechanism
    • Ha TU, Segev DL, Barbie D, Masiakos PT, Tran TT, Dombkowski D, et al. Mullerian inhibiting substance inhibits ovarian cell growth through an rb-independent mechanism. J Biol Chem 2000;275:37101-9.
    • (2000) J Biol Chem , vol.275 , pp. 37101-37109
    • Ha, T.U.1    Segev, D.L.2    Barbie, D.3    Masiakos, P.T.4    Tran, T.T.5    Dombkowski, D.6
  • 35
    • 10744226821 scopus 로고    scopus 로고
    • Proteomic profiling of the NCI-60 cancer cell lines using new high-density reverse-phase lysatemicroarrays
    • Nishizuka S, Charboneau L, Young L, Major S, Reinhold WC, Waltham M, et al. Proteomic profiling of the NCI-60 cancer cell lines using new high-density reverse-phase lysatemicroarrays. ProcNatl Acad SciUS A 2003;100:14229-34.
    • (2003) ProcNatl Acad SciUS A , vol.100 , pp. 14229-14234
    • Nishizuka, S.1    Charboneau, L.2    Young, L.3    Major, S.4    Reinhold, W.C.5    Waltham, M.6
  • 36
    • 79952713255 scopus 로고    scopus 로고
    • A unique spectrum of somatic PIK3CA (p110alpha) mutations within primary endometrial carcinomas
    • Rudd ML, Price JC, Fogoros S, Godwin AK, Sgroi DC, Merino MJ, et al. A unique spectrum of somatic PIK3CA (p110alpha) mutations within primary endometrial carcinomas. Clin Cancer Res 2011;17:1331-40.
    • (2011) Clin Cancer Res , vol.17 , pp. 1331-1340
    • Rudd, M.L.1    Price, J.C.2    Fogoros, S.3    Godwin, A.K.4    Sgroi, D.C.5    Merino, M.J.6
  • 37
    • 84905537957 scopus 로고    scopus 로고
    • DNA sequence profiles of the colorectal cancer critical gene set KRAS-BRAF-PIK3CA-PTEN-TP53 related to age at disease onset
    • Berg M, Danielsen SA, Ahlquist T, Merok MA, Agesen TH, Vatn MH, et al. DNA sequence profiles of the colorectal cancer critical gene set KRAS-BRAF-PIK3CA-PTEN-TP53 related to age at disease onset. PLoS ONE 2010;5:e13978.
    • (2010) PLoS ONE , vol.5
    • Berg, M.1    Danielsen, S.A.2    Ahlquist, T.3    Merok, M.A.4    Agesen, T.H.5    Vatn, M.H.6
  • 38
    • 0027942136 scopus 로고
    • The prostatic endocrine-paracrine (neuroendocrine) regulatory system and neuroendocrine differentiation in prostatic carcinoma: A review and future directions in basic research
    • Di Sant Agnese PA, Cockett AT. The prostatic endocrine-paracrine (neuroendocrine) regulatory system and neuroendocrine differentiation in prostatic carcinoma: a review and future directions in basic research. J Urol 1994;152(5 Pt 2):1927-31.
    • (1994) J Urol , vol.152 , Issue.5 PART 2 , pp. 1927-1931
    • Di Sant Agnese, P.A.1    Cockett, A.T.2
  • 39
    • 0032977146 scopus 로고    scopus 로고
    • Undifferentiated carcinoma of the prostate with small cell features: Immunohistochemical subtyping and reflections on histogenesis
    • Helpap B, Kollermann J. Undifferentiated carcinoma of the prostate with small cell features: immunohistochemical subtyping and reflections on histogenesis. Virchows Arch 1999;434:385-91.
    • (1999) Virchows Arch , vol.434 , pp. 385-391
    • Helpap, B.1    Kollermann, J.2
  • 40
  • 41
    • 58149116823 scopus 로고    scopus 로고
    • CD44 expression is a feature of prostatic small cell carcinoma and distinguishes it from its mimickers
    • Simon RA, di Sant'Agnese PA, Huang LS, Xu H, Yao JL, Yang Q, et al. CD44 expression is a feature of prostatic small cell carcinoma and distinguishes it from its mimickers. Hum Pathol 2009;40:252-8.
    • (2009) Hum Pathol , vol.40 , pp. 252-258
    • Simon, R.A.1    Di Sant'Agnese, P.A.2    Huang, L.S.3    Xu, H.4    Yao, J.L.5    Yang, Q.6
  • 42
    • 0033616597 scopus 로고    scopus 로고
    • RB-mediated suppression of spontaneous multiple neuroendocrine neoplasia and lung metastases in rb+/- mice
    • Nikitin AY, Juarez-Perez MI, Li S, Huang L, Lee WH. RB-mediated suppression of spontaneous multiple neuroendocrine neoplasia and lung metastases in rb+/- mice. Proc Natl Acad Sci U S A 1999;96: 3916-21.
    • (1999) Proc Natl Acad Sci U S A , vol.96 , pp. 3916-3921
    • Nikitin, A.Y.1    Juarez-Perez, M.I.2    Li, S.3    Huang, L.4    Lee, W.H.5
  • 43
    • 79958761641 scopus 로고    scopus 로고
    • Cell of origin of small cell lung cancer: Inactivation of Trp53 and Rb1 in distinct cell types of adult mouse lung
    • Sutherland KD, Proost N, Brouns I, Adriaensen D, Song JY, Berns A. Cell of origin of small cell lung cancer: inactivation of Trp53 and Rb1 in distinct cell types of adult mouse lung. Cancer Cell 2011;19: 754-64.
    • (2011) Cancer Cell , vol.19 , pp. 754-764
    • Sutherland, K.D.1    Proost, N.2    Brouns, I.3    Adriaensen, D.4    Song, J.Y.5    Berns, A.6
  • 45
    • 28544436228 scopus 로고    scopus 로고
    • Heterogeneous tumor evolution initiated by loss of pRb function in a preclinical prostate cancer model
    • Hill R, Song Y, Cardiff RD, Van Dyke T. Heterogeneous tumor evolution initiated by loss of pRb function in a preclinical prostate cancer model. Cancer Res 2005;65:10243-54.
    • (2005) Cancer Res , vol.65 , pp. 10243-10254
    • Hill, R.1    Song, Y.2    Cardiff, R.D.3    Van Dyke, T.4
  • 46
    • 34250822389 scopus 로고    scopus 로고
    • Prostate cancer associated with p53 and rb deficiency arises from the stem/progenitor cellenriched proximal region of prostatic ducts
    • Zhou Z, Flesken-Nikitin A, Nikitin AY. Prostate cancer associated with p53 and rb deficiency arises from the stem/progenitor cellenriched proximal region of prostatic ducts. Cancer Res 2007;67: 5683-90.
    • (2007) Cancer Res , vol.67 , pp. 5683-5690
    • Zhou, Z.1    Flesken-Nikitin, A.2    Nikitin, A.Y.3
  • 48
    • 84863013857 scopus 로고    scopus 로고
    • Modeling a lethal prostate cancer variant with small-cell carcinoma features
    • Tzelepi V, Zhang J, Lu JF, Kleb B, Wu G, Wan X, et al. Modeling a lethal prostate cancer variant with small-cell carcinoma features. Clin Cancer Res 2012;18:666-77.
    • (2012) Clin Cancer Res , vol.18 , pp. 666-677
    • Tzelepi, V.1    Zhang, J.2    Lu, J.F.3    Kleb, B.4    Wu, G.5    Wan, X.6
  • 49
    • 84879088895 scopus 로고    scopus 로고
    • Genetic markers associated with early cancer-specific mortality following prostatectomy
    • Liu W, Xie CC, Thomas CY, Kim ST, Lindberg J, Egevad L, et al. Genetic markers associated with early cancer-specific mortality following prostatectomy. Cancer 2013;119:2405-12.
    • (2013) Cancer , vol.119 , pp. 2405-2412
    • Liu, W.1    Xie, C.C.2    Thomas, C.Y.3    Kim, S.T.4    Lindberg, J.5    Egevad, L.6
  • 50
    • 78649888666 scopus 로고    scopus 로고
    • The retinoblastoma tumor suppressor controls androgen signaling and human prostate cancer progression
    • Sharma A, Yeow WS, Ertel A, Coleman I, Clegg N, Thangavel C, et al. The retinoblastoma tumor suppressor controls androgen signaling and human prostate cancer progression. J Clin Invest 2010;120:4478-92.
    • (2010) J Clin Invest , vol.120 , pp. 4478-4492
    • Sharma, A.1    Yeow, W.S.2    Ertel, A.3    Coleman, I.4    Clegg, N.5    Thangavel, C.6
  • 51
    • 84856530618 scopus 로고    scopus 로고
    • Common structural and epigenetic changes in the genome of castration-resistant prostate cancer
    • Friedlander TW, Roy R, Tomlins SA, Ngo VT, Kobayashi Y, Azameera A, et al. Common structural and epigenetic changes in the genome of castration-resistant prostate cancer. Cancer Res 2012;72:616-25.
    • (2012) Cancer Res , vol.72 , pp. 616-625
    • Friedlander, T.W.1    Roy, R.2    Tomlins, S.A.3    Ngo, V.T.4    Kobayashi, Y.5    Azameera, A.6
  • 52
    • 84856041279 scopus 로고    scopus 로고
    • TP53 mutations in serous tubal intraepithelial carcinoma and concurrent pelvic high-grade serous carcinoma-evidence supporting the clonal relationship of the two lesions
    • Kuhn E, Kurman RJ, Vang R, Sehdev AS, Han G, Soslow R, et al. TP53 mutations in serous tubal intraepithelial carcinoma and concurrent pelvic high-grade serous carcinoma-evidence supporting the clonal relationship of the two lesions. J Pathol 2012;226:421-6.
    • (2012) J Pathol , vol.226 , pp. 421-426
    • Kuhn, E.1    Kurman, R.J.2    Vang, R.3    Sehdev, A.S.4    Han, G.5    Soslow, R.6
  • 53
    • 84862650290 scopus 로고    scopus 로고
    • Pathogenesis of prostatic small cell carcinoma involves the inactivation of the P53 pathway
    • Chen H, Sun Y, Wu C, Magyar CE, Li X, Cheng L, et al. Pathogenesis of prostatic small cell carcinoma involves the inactivation of the P53 pathway. Endocr Relat Cancer 2012;19:321-31.
    • (2012) Endocr Relat Cancer , vol.19 , pp. 321-331
    • Chen, H.1    Sun, Y.2    Wu, C.3    Magyar, C.E.4    Li, X.5    Cheng, L.6
  • 54
    • 80054051518 scopus 로고    scopus 로고
    • Time to stratify? the retinoblastoma protein in castrate-resistant prostate cancer
    • Aparicio A, Den RB, Knudsen KE. Time to stratify? the retinoblastoma protein in castrate-resistant prostate cancer. Nat Rev Urol 2011;8: 562-8.
    • (2011) Nat Rev Urol , vol.8 , pp. 562-568
    • Aparicio, A.1    Den, R.B.2    Knudsen, K.E.3
  • 55
    • 3242715058 scopus 로고    scopus 로고
    • Hyperphosphorylation of pRb: A mechanism for RB tumour suppressor pathway inactivation in bladder cancer
    • Chatterjee SJ, George B, Goebell PJ, Alavi-Tafreshi M, Shi SR, Fung YK, et al. Hyperphosphorylation of pRb: a mechanism for RB tumour suppressor pathway inactivation in bladder cancer. J Pathol 2004;203: 762-70.
    • (2004) J Pathol , vol.203 , pp. 762-770
    • Chatterjee, S.J.1    George, B.2    Goebell, P.J.3    Alavi-Tafreshi, M.4    Shi, S.R.5    Fung, Y.K.6
  • 56
    • 4644257541 scopus 로고    scopus 로고
    • Rb family proteins differentially regulate distinct cell lineages during epithelial development
    • Wikenheiser-Brokamp KA. Rb family proteins differentially regulate distinct cell lineages during epithelial development. Development 2004;131:4299-310.
    • (2004) Development , vol.131 , pp. 4299-4310
    • Wikenheiser-Brokamp, K.A.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.